Indium tin oxide （ITO） nano-particles were prepared directly using waste ITO target, which had been coated by magnetron controlled sputtering. The waste ITO target was cleaned with de-ionized water, and then dissolv...Indium tin oxide （ITO） nano-particles were prepared directly using waste ITO target, which had been coated by magnetron controlled sputtering. The waste ITO target was cleaned with de-ionized water, and then dissolved in acid, filtrated, neutralized, manipulated through azeotropic distillation and finally dried, and in this way the precursor of indium tin hydroxide was obtained. The nanosized rio composite powder was prepared after the precursor heat-treated at 500℃ for 2 h. TEM images show a narrow distribution of particle size is 5-20 nm and the particle size can be controlled. Its granule has a spherical shape and the dispersion of the particle is well. X-ray diffraction （XRD） patterns indicate the only cubic In2O3 phase in the ITO powder hot-treated at 500℃. The purity of ITO composite powder is 99.9907%. The content of radium within filtrate was detected by using the EDTA titration of determination of indium in the ITO powder and ITO target. Appropriate amount of SnCl4.5H2O was dissolved in the filtrate, and then ITO powder containing 10 wt.% SnO2 was successfully prepared by heat-treating.展开更多
目的:基于网络药理学与分子对接探究五子散治疗宫腔镜术后疼痛的作用机制。方法:在中药系统药理学数据库与分析平台(Traditional Chinese Medicine Systems Pharmacology,TCMSP)检索五子散活性成分,利用Swiss Target Prediction平台预...目的:基于网络药理学与分子对接探究五子散治疗宫腔镜术后疼痛的作用机制。方法:在中药系统药理学数据库与分析平台(Traditional Chinese Medicine Systems Pharmacology,TCMSP)检索五子散活性成分,利用Swiss Target Prediction平台预测靶点。采用GeneCards、OMIM等数据库获取宫腔镜术后疼痛相关疾病靶点。基于String平台构建蛋白互作网络。通过David数据库,进行基因本体论(Gene ontology,GO)与京都基因与基因组百科全书(Kyoto encyclopedia of genes and genomes,KEGG)富集分析。最后,利用分子对接验证核心靶点及成分。结果:筛选出20种有效活性成分,获得1582个相关疾病靶点,确定治疗宫腔镜术后疼痛的潜在靶点153个。治疗宫腔镜术后疼痛的主要活性成分为槲皮素(Quercetin)、6-羟基吴茱萸次碱(6-OH-Luteolin)、木犀草素(Luteolin)、异鼠李素(Isorhamnetin)和山柰酚(Kaempferol),预测关键靶点为甘油醛-3-磷酸脱氢酶(glyceraldehyde-3-phosphate dehydrogenase,GAPDH)、AKT丝氨酸/苏氨酸激酶1(AKT serine/threonine kinase 1,AKT1)、信号传导及转录激活因子3(Signal transducer and activator of transcription3,STAT3)、表皮生长因子受体(Epidermal growth factor receptor,EGFR)和半胱天冬酶3(Caspase 3,apoptosis-related cysteine peptidase,CASP3)。治疗宫腔镜术后疼痛主要通过调控AGE-RAGE信号通路发挥抗炎、抗氧化及镇痛等作用。结论:五子散通过多成分协同-多靶点-多通路协同介导镇痛,初步揭示五子散治疗宫腔镜术后疼痛的机制。展开更多
Ba-Al-S-Eu sputtering target for blue emitting phosphors was prepared by powder sintering method. XRD patterns showed that the main components of the target were barium tetra aluminum sulfide （BaAl4S7）, bariutm sulf...Ba-Al-S-Eu sputtering target for blue emitting phosphors was prepared by powder sintering method. XRD patterns showed that the main components of the target were barium tetra aluminum sulfide （BaAl4S7）, bariutm sulfide （BaS）, and europium sulfide （EuS）. In the samples, part of the barium and aluminum are formed into barium aluminum oxide （BaAl2O4） with the impurity element of oxygen. The PL characteristic spectra of the target showed the 470 nm blue emission obviously, and the Ba-Al-S thin films also transmitted a purple-blue emission at the position of 440 nm.The results indicated that this method was suitable for the fabrication of the Ba-Al-S：Eu sputtering target.展开更多
对铟锡氧化物ITO(Indium Tin Oxide)纳米粉末的制备方法如均相共沉淀法,水溶液共沉淀法,电解法,溶胶-凝胶法,喷雾燃烧法,喷雾热分解法等以及ITO磁控溅射靶的现有几种制备工艺进行了综合评述。阐述了各种制备工艺过程和工作原理,比较和...对铟锡氧化物ITO(Indium Tin Oxide)纳米粉末的制备方法如均相共沉淀法,水溶液共沉淀法,电解法,溶胶-凝胶法,喷雾燃烧法,喷雾热分解法等以及ITO磁控溅射靶的现有几种制备工艺进行了综合评述。阐述了各种制备工艺过程和工作原理,比较和分析了各工艺方法的优缺点,并提出了制备高品质ITO粉末及ITO靶的努力方向。展开更多
黑火药是一种经典的点火药,但其在低气压环境(高空)下的燃烧性能却鲜有研究。为了了解黑火药的低压燃烧性能,采用光-电靶法测试了不同药柱密度、不同温度和不同低压条件下高密度压实黑火药柱的燃速。研究结果表明,黑火药柱的燃速随环境...黑火药是一种经典的点火药,但其在低气压环境(高空)下的燃烧性能却鲜有研究。为了了解黑火药的低压燃烧性能,采用光-电靶法测试了不同药柱密度、不同温度和不同低压条件下高密度压实黑火药柱的燃速。研究结果表明,黑火药柱的燃速随环境压力的下降快速变小,燃速与环境压力呈线性关系。当环境压力下降到20 k Pa时,黑火药柱会出现瞎火或断火的现象;药柱密度增大,黑火药柱燃速逐渐变小,药柱密度对黑火药柱燃速的影响会随着环境压力的降低逐渐变大;温度升高,黑火药柱的燃速缓慢变大,同时温度对黑火药柱燃速的影响会随着环境压力的降低逐渐变小。也就是说,低压环境中,环境压力对黑火药柱燃速的影响比药柱密度和温度对黑火药柱燃速的影响要更大。通过双因素的数学拟合,建立了黑火药柱的燃速随环境压力和温度的变化规律。展开更多
基金This work was financially supported by the National "863 " program of China (No. 2004AA303542).
文摘Indium tin oxide （ITO） nano-particles were prepared directly using waste ITO target, which had been coated by magnetron controlled sputtering. The waste ITO target was cleaned with de-ionized water, and then dissolved in acid, filtrated, neutralized, manipulated through azeotropic distillation and finally dried, and in this way the precursor of indium tin hydroxide was obtained. The nanosized rio composite powder was prepared after the precursor heat-treated at 500℃ for 2 h. TEM images show a narrow distribution of particle size is 5-20 nm and the particle size can be controlled. Its granule has a spherical shape and the dispersion of the particle is well. X-ray diffraction （XRD） patterns indicate the only cubic In2O3 phase in the ITO powder hot-treated at 500℃. The purity of ITO composite powder is 99.9907%. The content of radium within filtrate was detected by using the EDTA titration of determination of indium in the ITO powder and ITO target. Appropriate amount of SnCl4.5H2O was dissolved in the filtrate, and then ITO powder containing 10 wt.% SnO2 was successfully prepared by heat-treating.
文摘目的:基于网络药理学与分子对接探究五子散治疗宫腔镜术后疼痛的作用机制。方法:在中药系统药理学数据库与分析平台(Traditional Chinese Medicine Systems Pharmacology,TCMSP)检索五子散活性成分,利用Swiss Target Prediction平台预测靶点。采用GeneCards、OMIM等数据库获取宫腔镜术后疼痛相关疾病靶点。基于String平台构建蛋白互作网络。通过David数据库,进行基因本体论(Gene ontology,GO)与京都基因与基因组百科全书(Kyoto encyclopedia of genes and genomes,KEGG)富集分析。最后,利用分子对接验证核心靶点及成分。结果:筛选出20种有效活性成分,获得1582个相关疾病靶点,确定治疗宫腔镜术后疼痛的潜在靶点153个。治疗宫腔镜术后疼痛的主要活性成分为槲皮素(Quercetin)、6-羟基吴茱萸次碱(6-OH-Luteolin)、木犀草素(Luteolin)、异鼠李素(Isorhamnetin)和山柰酚(Kaempferol),预测关键靶点为甘油醛-3-磷酸脱氢酶(glyceraldehyde-3-phosphate dehydrogenase,GAPDH)、AKT丝氨酸/苏氨酸激酶1(AKT serine/threonine kinase 1,AKT1)、信号传导及转录激活因子3(Signal transducer and activator of transcription3,STAT3)、表皮生长因子受体(Epidermal growth factor receptor,EGFR)和半胱天冬酶3(Caspase 3,apoptosis-related cysteine peptidase,CASP3)。治疗宫腔镜术后疼痛主要通过调控AGE-RAGE信号通路发挥抗炎、抗氧化及镇痛等作用。结论:五子散通过多成分协同-多靶点-多通路协同介导镇痛,初步揭示五子散治疗宫腔镜术后疼痛的机制。
基金supported by Provincial Natural Science Foundation of Beijing (3063022)
文摘Ba-Al-S-Eu sputtering target for blue emitting phosphors was prepared by powder sintering method. XRD patterns showed that the main components of the target were barium tetra aluminum sulfide （BaAl4S7）, bariutm sulfide （BaS）, and europium sulfide （EuS）. In the samples, part of the barium and aluminum are formed into barium aluminum oxide （BaAl2O4） with the impurity element of oxygen. The PL characteristic spectra of the target showed the 470 nm blue emission obviously, and the Ba-Al-S thin films also transmitted a purple-blue emission at the position of 440 nm.The results indicated that this method was suitable for the fabrication of the Ba-Al-S：Eu sputtering target.
文摘对铟锡氧化物ITO(Indium Tin Oxide)纳米粉末的制备方法如均相共沉淀法,水溶液共沉淀法,电解法,溶胶-凝胶法,喷雾燃烧法,喷雾热分解法等以及ITO磁控溅射靶的现有几种制备工艺进行了综合评述。阐述了各种制备工艺过程和工作原理,比较和分析了各工艺方法的优缺点,并提出了制备高品质ITO粉末及ITO靶的努力方向。
文摘黑火药是一种经典的点火药,但其在低气压环境(高空)下的燃烧性能却鲜有研究。为了了解黑火药的低压燃烧性能,采用光-电靶法测试了不同药柱密度、不同温度和不同低压条件下高密度压实黑火药柱的燃速。研究结果表明,黑火药柱的燃速随环境压力的下降快速变小,燃速与环境压力呈线性关系。当环境压力下降到20 k Pa时,黑火药柱会出现瞎火或断火的现象;药柱密度增大,黑火药柱燃速逐渐变小,药柱密度对黑火药柱燃速的影响会随着环境压力的降低逐渐变大;温度升高,黑火药柱的燃速缓慢变大,同时温度对黑火药柱燃速的影响会随着环境压力的降低逐渐变小。也就是说,低压环境中,环境压力对黑火药柱燃速的影响比药柱密度和温度对黑火药柱燃速的影响要更大。通过双因素的数学拟合,建立了黑火药柱的燃速随环境压力和温度的变化规律。
