In eukaryotes, crossovers together with sister chromatid cohesion maintain physical association between homologous chromosomes, ensuring accurate chromosome segregation during meiosis I and resulting in exchange of ge...In eukaryotes, crossovers together with sister chromatid cohesion maintain physical association between homologous chromosomes, ensuring accurate chromosome segregation during meiosis I and resulting in exchange of genetic information between homologues. The Arabidopsis PTD （Parting Dancers） gene affects the level of meiotic crossover formation, but its functional relationships with other core meiotic genes, such as AtSP011-1, AtRAD51, and AtMSH4, are unclear; whether PTD has other functions in meiosis is also unknown. To further analyze PTD function and to test for epistatic relationships, we compared the meiotic chromosome behaviors ofAtspoll-1 ptd and Atrad51 ptd double mutants with the relevant single mutants. The results suggest that PTD functions downstream of AtSP011-1 and AtRAD51 in the meiotic recombination pathway. Furthermore, we found that meiotic defects in rck pM and Atmsh4 ptd double mutants showed similar meiotic phenotypes to those of the relevant single mutants, providing genetic evidences for roles of PTD and RCK in the type I crossovers pathway. Moreover, we employed a pollen tetrad-based fluorescence method and found that the meiotic crossover frequencies in two genetic intervals were significantly reduced from 6.63% and 22.26% in wild-type to 1.14% and 6.36%, respectively, in the ptd^2 mutant. These results revealed new aspects of PTD function in meiotic crossover formation.展开更多
The open-loop crossover frequency is pointed as an important parameter for practical autopilot design. Since different gain designs may achieve the same open-loop crossover frequency, it should be neither considered a...The open-loop crossover frequency is pointed as an important parameter for practical autopilot design. Since different gain designs may achieve the same open-loop crossover frequency, it should be neither considered as a performance objective of the optimal autopilot design-schemes nor neglected. Besides, the main assignment of the autopilot is to drive the missile to track the acceleration commands, so the autopilot gain design should be evaluated directly according to the resultant tracking performance. For this purpose, an optimal design methodology of the three-loop missile autopilot is introduced based on constraint optimization technique, where the tracking performance is established analytically as the design objective and the open-loop crossover frequency is formed as inequality constraint function, both are manipulated in terms of stable characteristic parameters of the autopilot closed-loop. The proposed technique is implemented with the assistance of a numerical optimization algorithm which automatically adjusts the design parameters. Finally, numerical simulation results are provided to demonstrate the effectiveness and feasibility of the proposed approach compared with that in some references.展开更多
A predictive model of meiotic crossover engineering would increase precision in crop breeding.We review the biological principles underlying crossover formation and chromosomal distribution,hierarchical control mechan...A predictive model of meiotic crossover engineering would increase precision in crop breeding.We review the biological principles underlying crossover formation and chromosomal distribution,hierarchical control mechanisms enforcing crossover assurance,and an emerging phase-separation model determining crossover interference patterning.展开更多
In this paper, a new numerical simulation approach is proposed for the study of open-loop frequency response of a chaotic masking system. Using Chua＇s circuit and the Lorenz system as illustrative examples, we have s...In this paper, a new numerical simulation approach is proposed for the study of open-loop frequency response of a chaotic masking system. Using Chua＇s circuit and the Lorenz system as illustrative examples, we have shown that one can employ chaos synchronization to separate the feedback network from a chaotic masking system, and then use numerical simulation to obtain the open-loop synchronization response, the phase response, and the amplitude response of a chaotic masking system. Based on the analysis of the frequency response, we have also proved that changing the amplitude of the exciting （input） signal within normal working domain does not influence the frequency response of the chaotic masking system. The new numerical simulation method developed in this paper can be extended to consider the open-loop frequency response of other systems described by differential or difference equations.展开更多
Micrometric-thin cells(MCs)with alkali vapor atoms have been valuable for research and applications of hyperfine Zeeman splitting and atomic magnetometers under strong magnetic fields.We theoretically and experimental...Micrometric-thin cells(MCs)with alkali vapor atoms have been valuable for research and applications of hyperfine Zeeman splitting and atomic magnetometers under strong magnetic fields.We theoretically and experimentally study the saturated absorption spectra using a 100-μm cesium MC,where the pump and probe beams are linearly polarized with mutually perpendicular polarizations,and the magnetic field is along the pump beam.Because of the distinctive thin chamber of the MC,crossover spectral lines in saturated absorption spectra are largely suppressed leading to clear splittings of hyperfine Zeeman transitions in experiments,and the effect of spatial magnetic field gradient is expected to be reduced.A calculation method is proposed to achieve good agreements between theoretical calculations and experimental results.This method successfully explains the suppression of crossover lines in MCs,as well as the effects of magnetic field direction,propagation and polarization directions of the pump/probe beam on saturated absorption spectrum.The saturated absorption spectrum with suppressed crossover lines is used for laser frequency stabilization,which may provide the potential value of MCs for high spatial resolution strong-field magnetometry with high sensitivity.展开更多
系统的大功率缺额易引起较大的频率偏移。频率偏移过大可能导致直流系统(high voltage DC transmission,HVDC)触发脉冲异常,进而引发运行问题。以实际系统MACH2(modular advanced control hardware 2)为例,分析了触发控制原理及锁相环...系统的大功率缺额易引起较大的频率偏移。频率偏移过大可能导致直流系统(high voltage DC transmission,HVDC)触发脉冲异常,进而引发运行问题。以实际系统MACH2(modular advanced control hardware 2)为例,分析了触发控制原理及锁相环工作原理,重点研究了系统频率变化对锁相环工作及换相电压过零点判断的影响。在PSCAD/EMTDC仿真平台中搭建了MACH2触发环节的简化模型,仿真结果表明,频率变化会影响系统触发脉冲的产生,导致实际触发延迟角无法及时跟踪指令值,但对系统运行的影响不大。由于控制系统触发延迟角幅值限制环节的影响,系统频率升高及降低两种情况对直流系统的影响程度也有差别。展开更多
针对直流调速系统,设计了一种模糊自整定的分数阶内模控制器。首先将分数阶理论与内模控制(internal model control,IM C)相结合设计分数阶内模控制器,其参数可根据系统的相角裕度和穿越频率进行解析整定;然后在分析了相角裕度和穿越频...针对直流调速系统,设计了一种模糊自整定的分数阶内模控制器。首先将分数阶理论与内模控制(internal model control,IM C)相结合设计分数阶内模控制器,其参数可根据系统的相角裕度和穿越频率进行解析整定;然后在分析了相角裕度和穿越频率对系统性能影响的基础上,设计出模糊控制器,实现了系统根据转速偏差和偏差变化对控制器参数的在线自整定,克服了系统性能对相角裕度和穿越频率选择的依赖。仿真和试验结果表明模糊自整定分数阶内模控制器可使系统具有良好的动态响应、干扰抑制特性以及克服参数摄动的鲁棒性。展开更多
基金supported by funds from Fudan Universityfunds from Rijk Zwaan,the Netherlands,and the Biology Department and the Huck Institutes of the Life Sciences at the Pennsylvania State University in USA
文摘In eukaryotes, crossovers together with sister chromatid cohesion maintain physical association between homologous chromosomes, ensuring accurate chromosome segregation during meiosis I and resulting in exchange of genetic information between homologues. The Arabidopsis PTD （Parting Dancers） gene affects the level of meiotic crossover formation, but its functional relationships with other core meiotic genes, such as AtSP011-1, AtRAD51, and AtMSH4, are unclear; whether PTD has other functions in meiosis is also unknown. To further analyze PTD function and to test for epistatic relationships, we compared the meiotic chromosome behaviors ofAtspoll-1 ptd and Atrad51 ptd double mutants with the relevant single mutants. The results suggest that PTD functions downstream of AtSP011-1 and AtRAD51 in the meiotic recombination pathway. Furthermore, we found that meiotic defects in rck pM and Atmsh4 ptd double mutants showed similar meiotic phenotypes to those of the relevant single mutants, providing genetic evidences for roles of PTD and RCK in the type I crossovers pathway. Moreover, we employed a pollen tetrad-based fluorescence method and found that the meiotic crossover frequencies in two genetic intervals were significantly reduced from 6.63% and 22.26% in wild-type to 1.14% and 6.36%, respectively, in the ptd^2 mutant. These results revealed new aspects of PTD function in meiotic crossover formation.
文摘The open-loop crossover frequency is pointed as an important parameter for practical autopilot design. Since different gain designs may achieve the same open-loop crossover frequency, it should be neither considered as a performance objective of the optimal autopilot design-schemes nor neglected. Besides, the main assignment of the autopilot is to drive the missile to track the acceleration commands, so the autopilot gain design should be evaluated directly according to the resultant tracking performance. For this purpose, an optimal design methodology of the three-loop missile autopilot is introduced based on constraint optimization technique, where the tracking performance is established analytically as the design objective and the open-loop crossover frequency is formed as inequality constraint function, both are manipulated in terms of stable characteristic parameters of the autopilot closed-loop. The proposed technique is implemented with the assistance of a numerical optimization algorithm which automatically adjusts the design parameters. Finally, numerical simulation results are provided to demonstrate the effectiveness and feasibility of the proposed approach compared with that in some references.
基金funded by the National Natural Science Foundation of China(U2102219 and 32370901)the Project of Zhongshan Biological Breeding Laboratory(ZSBBL-KY2023-06-3).
文摘A predictive model of meiotic crossover engineering would increase precision in crop breeding.We review the biological principles underlying crossover formation and chromosomal distribution,hierarchical control mechanisms enforcing crossover assurance,and an emerging phase-separation model determining crossover interference patterning.
文摘In this paper, a new numerical simulation approach is proposed for the study of open-loop frequency response of a chaotic masking system. Using Chua＇s circuit and the Lorenz system as illustrative examples, we have shown that one can employ chaos synchronization to separate the feedback network from a chaotic masking system, and then use numerical simulation to obtain the open-loop synchronization response, the phase response, and the amplitude response of a chaotic masking system. Based on the analysis of the frequency response, we have also proved that changing the amplitude of the exciting （input） signal within normal working domain does not influence the frequency response of the chaotic masking system. The new numerical simulation method developed in this paper can be extended to consider the open-loop frequency response of other systems described by differential or difference equations.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61571018 and 61531003).
文摘Micrometric-thin cells(MCs)with alkali vapor atoms have been valuable for research and applications of hyperfine Zeeman splitting and atomic magnetometers under strong magnetic fields.We theoretically and experimentally study the saturated absorption spectra using a 100-μm cesium MC,where the pump and probe beams are linearly polarized with mutually perpendicular polarizations,and the magnetic field is along the pump beam.Because of the distinctive thin chamber of the MC,crossover spectral lines in saturated absorption spectra are largely suppressed leading to clear splittings of hyperfine Zeeman transitions in experiments,and the effect of spatial magnetic field gradient is expected to be reduced.A calculation method is proposed to achieve good agreements between theoretical calculations and experimental results.This method successfully explains the suppression of crossover lines in MCs,as well as the effects of magnetic field direction,propagation and polarization directions of the pump/probe beam on saturated absorption spectrum.The saturated absorption spectrum with suppressed crossover lines is used for laser frequency stabilization,which may provide the potential value of MCs for high spatial resolution strong-field magnetometry with high sensitivity.
文摘系统的大功率缺额易引起较大的频率偏移。频率偏移过大可能导致直流系统(high voltage DC transmission,HVDC)触发脉冲异常,进而引发运行问题。以实际系统MACH2(modular advanced control hardware 2)为例,分析了触发控制原理及锁相环工作原理,重点研究了系统频率变化对锁相环工作及换相电压过零点判断的影响。在PSCAD/EMTDC仿真平台中搭建了MACH2触发环节的简化模型,仿真结果表明,频率变化会影响系统触发脉冲的产生,导致实际触发延迟角无法及时跟踪指令值,但对系统运行的影响不大。由于控制系统触发延迟角幅值限制环节的影响,系统频率升高及降低两种情况对直流系统的影响程度也有差别。
文摘针对直流调速系统,设计了一种模糊自整定的分数阶内模控制器。首先将分数阶理论与内模控制(internal model control,IM C)相结合设计分数阶内模控制器,其参数可根据系统的相角裕度和穿越频率进行解析整定;然后在分析了相角裕度和穿越频率对系统性能影响的基础上,设计出模糊控制器,实现了系统根据转速偏差和偏差变化对控制器参数的在线自整定,克服了系统性能对相角裕度和穿越频率选择的依赖。仿真和试验结果表明模糊自整定分数阶内模控制器可使系统具有良好的动态响应、干扰抑制特性以及克服参数摄动的鲁棒性。
