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BP230-IgG抗体阳性的大疱性类天疱疮患者致病特征的初步探究
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作者 刘玮 曾志良 +1 位作者 马玲 陈柳青 《临床皮肤科杂志》 北大核心 2026年第1期36-40,共5页
目的探讨BP230-IgG抗体阳性的大疱性类天疱疮(BP)患者的致病特征。方法根据BP230-IgG和BP180-IgG抗体表达水平,将患者分为BP230-IgG+BP180-IgG-组(单阳组,4例)、BP230-IgG+BP180-IgG+组(双阳组,30例)和BP230-IgG-BP180-IgG+组(阴性组,30... 目的探讨BP230-IgG抗体阳性的大疱性类天疱疮(BP)患者的致病特征。方法根据BP230-IgG和BP180-IgG抗体表达水平,将患者分为BP230-IgG+BP180-IgG-组(单阳组,4例)、BP230-IgG+BP180-IgG+组(双阳组,30例)和BP230-IgG-BP180-IgG+组(阴性组,30例),分析3组患者治疗前基线临床特征、实验室检查结果、治疗后反应、BP180-IgG及BP230-IgG抗体表达水平等。结果双阳组tIgE水平[(1323.38±972.26)kIU/L]均高于单阳组及阴性组,差异均有统计学意义(P<0.05);双阳组合并症发生率(73.30%)高于阴性组(36.67%),差异有统计学意义(P<0.05);双阳组皮损平均控制时间较长,但3组比较差异无统计学意义(P>0.05)。单阳性4例患者均为轻中度BP,未出现黏膜受累,治疗仅单一口服或外用糖皮质激素。三组患者皮损均伴瘙痒及炎症反应剧烈,基线BP180-IgG和BP230-IgG抗体表达水平均与tIgE水平成正相关(P<0.05)。结论单独BP230-IgG诱发的BP临床发病率低、病情较轻及治疗反应好;BP230-IgG+BP180-IgG+双阳组患者合并症发生率较高、tIgE水平升高、炎症反应更强烈及控制新发水疱难度更大;但BP230-IgG致病的详细分子机制仍有待进一步研究证实。 展开更多
关键词 大疱性类天疱疮 BP230 igg抗体 嗜酸性粒细胞 总IGE
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实验室确诊风疹病例风疹病毒IgG抗体亲和力特征
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作者 秦月 张增峰 +5 位作者 邓丽丽 韦一知 韦敬航 刘静 马宇燕 梁亮 《热带医学杂志》 2026年第1期101-104,142,共5页
目的分析风疹病例风疹病毒(RuV)IgG抗体亲和力的性别、年龄和免疫史分布特征,为风疹防控提供亲和力数据。方法运用基于酶联免疫吸附试验的尿素变性亲和力检测方法,检测2018-2023年广西壮族自治区风疹监测网络实验室确诊风疹病例RuV IgG... 目的分析风疹病例风疹病毒(RuV)IgG抗体亲和力的性别、年龄和免疫史分布特征,为风疹防控提供亲和力数据。方法运用基于酶联免疫吸附试验的尿素变性亲和力检测方法,检测2018-2023年广西壮族自治区风疹监测网络实验室确诊风疹病例RuV IgG阳性者血清IgG抗体亲和力,分析相对亲和力指数(RAI)均值和高/中/低亲和力比例。结果在291例RuV IgG阳性的风疹病例中,RuV IgG RAI均值为34.47%,高、中、低亲和力病例占比分别为24.05%(70/291)、26.46%(77/291)、49.48%(144/291)。RuV IgG RAI均值由<8月龄的20.44%上升至3~<10岁的60.11%(F=10.85,P<0.001),10~<15岁下降为29.96%,随后保持在较低水平(F=1.65,P=0.18)。RuV IgG高亲和力病例占比由<8月龄0.00%上升至3~<10岁66.67%,差异有统计学意义(趋势χ^(2)=6.66,P<0.05),10~<15岁下降为19.57%。含风疹成分疫苗(RCV)由0剂次到2剂次,RuV IgG RAI均值由29.86%升高至66.22%,差异有统计学意义(F=42.63,P<0.001);RuV IgG高亲和力占比由19.10%升高至77.78%,差异有统计学意义(趋势χ^(2)=10.10,P<0.05)。结论风疹抗体亲和力随RCV免疫剂次增加呈升高趋势,应按免疫程序全程接种疫苗。3~<10岁病例亲和力最高,10~<15岁及20~<30岁病例的抗体亲和力下降或较低,有必要在小学生或中学生入学时再接种1剂RCV,以及对育龄期妇女加强接种1剂RCV。 展开更多
关键词 风疹病毒 igg抗体 亲和力
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Accumulative-Error-Based Event-Triggered Control for Discrete-Time Linear Systems:A Discrete-Time Looped Functional Method 被引量:1
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作者 Xian-Ming Zhang Qing-Long Han +1 位作者 Xiaohua Ge Bao-Lin Zhang 《IEEE/CAA Journal of Automatica Sinica》 2025年第4期683-693,共11页
This paper is concerned with event-triggered control of discrete-time systems with or without input saturation.First,an accumulative-error-based event-triggered scheme is devised for control updates.When the accumulat... This paper is concerned with event-triggered control of discrete-time systems with or without input saturation.First,an accumulative-error-based event-triggered scheme is devised for control updates.When the accumulated error between the current state and the latest control update exceeds a certain threshold,an event is triggered.Such a scheme can ensure the event-generator works at a relatively low rate rather than falls into hibernation especially after the system steps into its steady state.Second,the looped functional method for continuous-time systems is extended to discrete-time systems.By introducing an innovative looped functional that links the event-triggered scheme,some sufficient conditions for the co-design of control gain and event-triggered parameters are obtained in terms of linear matrix inequalities with a couple of tuning parameters.Then,the proposed method is applied to discrete-time systems with input saturation.As a result,both suitable control gains and event-triggered parameters are also co-designed to ensure the system trajectories converge to the region of attraction.Finally,an unstable reactor system and an inverted pendulum system are given to show the effectiveness of the proposed method. 展开更多
关键词 Discrete-time linear systems event-triggered control input saturation looped functional method
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基于血清IgM及IgG抗体水平探讨儿童肺炎支原体肺炎的病情预测及药物治疗
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作者 舒玲 王宏勇 李蓬 《儿科药学杂志》 2026年第1期30-33,共4页
目的:基于血清肺炎支原体(MP)IgM抗体(MP-IgM)、MP-IgG表达探讨儿童肺炎支原体肺炎(MPP)的病情预测及诊治策略。方法:选取2024年4-10月于我院就诊的120例MPP患儿(疾病组)和100例体检健康的儿童(健康组),疾病组分为重度组52例与轻度组68... 目的:基于血清肺炎支原体(MP)IgM抗体(MP-IgM)、MP-IgG表达探讨儿童肺炎支原体肺炎(MPP)的病情预测及诊治策略。方法:选取2024年4-10月于我院就诊的120例MPP患儿(疾病组)和100例体检健康的儿童(健康组),疾病组分为重度组52例与轻度组68例。磁微粒化学发光法分析血清MP-IgM、MP-IgG表达水平,并以受试者工作特征(ROC)分析其对重症MPP的预测价值。结果:疾病组血清MP-IgM、MP-IgG水平高于健康组,且重度组高于轻度组(P均<0.05)。重度组发热时间、C反应蛋白高于轻度组,氧合指数低于轻度组(P均<0.05)。血清MP-IgM、MP-IgG联合预测重症MPP的AUC高于单独预测(P<0.05)。结论:血清MP-IGM、MP-IGG表达水平是预测重症MPP的高效生物学标志物,且联合预测效能更高;通过量化MP-IgM、MP-IgG预测效能,可根据疾病严重程度制定合理的分级干预方案,为个体化治疗提供参考。 展开更多
关键词 肺炎支原体肺炎 儿童 肺炎支原体IGM抗体 肺炎支原体igg抗体 病情预测 诊治策略
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肾透明细胞肾细胞癌合并IgG4相关性疾病1例
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作者 张博 仲林 《临床与实验病理学杂志》 北大核心 2026年第1期132-134,共3页
IgG4相关性疾病(immunoglobulin-G4 related disease,IgG4-RD)是一种免疫介导的慢性纤维炎性疾病,可累及多个系统及器官。目前IgG4-RD合并恶性肿瘤且累及同一部位的病例鲜有报道。本文报道1例72岁男性患者,以肾脏肿瘤入院,结合镜检、免... IgG4相关性疾病(immunoglobulin-G4 related disease,IgG4-RD)是一种免疫介导的慢性纤维炎性疾病,可累及多个系统及器官。目前IgG4-RD合并恶性肿瘤且累及同一部位的病例鲜有报道。本文报道1例72岁男性患者,以肾脏肿瘤入院,结合镜检、免疫表型及血清学测定最终诊断为肾透明细胞肾细胞癌合并IgG4-RD。由于IgG4-RD缺少临床特异性,容易在诊治过程中被忽略,本例意在提示IgG4-RD与肿瘤同时存在的可能性,且两者之间的发生可能存在相关性,为诊断及研究提供新的思路,避免漏诊及误诊。 展开更多
关键词 igg4相关性疾病 肾细胞癌 免疫球蛋白G 病例报道
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1例IgG4相关性硬化性胆管炎并胰腺炎
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作者 雷凤 黄志华 周美云 《中国CT和MRI杂志》 2026年第1期203-206,共4页
IgG4相关性硬化性胆管炎(IgG4-associated sclerosing cholangitis,IgG4-SC)属于硬化性胆管炎的一种^([1]),它亦被证实为IgG4相关性疾病(IgG4-related disease,IgG4-RD)的一部分^([2])。血清学检测方法常以IgG4升高为特征。IgG4-SC与PS... IgG4相关性硬化性胆管炎(IgG4-associated sclerosing cholangitis,IgG4-SC)属于硬化性胆管炎的一种^([1]),它亦被证实为IgG4相关性疾病(IgG4-related disease,IgG4-RD)的一部分^([2])。血清学检测方法常以IgG4升高为特征。IgG4-SC与PSC、继发性硬化性胆管炎、肝门区胆管恶性肿瘤等存在异病同症、异病同影现象,不少患者被误诊行不必要的手术。现将我院收治的一例误诊的IgG4相关性胆管炎并胰腺炎进行病例报道。 展开更多
关键词 igg4相关性疾病 igg4相关性硬化性胆管炎 自身免疫性胰腺炎
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IgG4相关硬化性胆管炎一例病例报告并文献复习
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作者 杨舵 李丽鑫 +2 位作者 王晓彤 蒋盈盈 白玉萍 《磁共振成像》 北大核心 2026年第2期139-141,168,共4页
本研究遵守《赫尔辛基宣言》,经兰州大学第二医院伦理委员会审核批准,免除受试者知情同意,批准文号:2025A-1333。患者女,60岁,两周前无明显诱因出现上腹部胀痛不适,以右上腹为著,就诊于当地医院,行相关检查诊断肝占位性病变,未完全缓解... 本研究遵守《赫尔辛基宣言》,经兰州大学第二医院伦理委员会审核批准,免除受试者知情同意,批准文号:2025A-1333。患者女,60岁,两周前无明显诱因出现上腹部胀痛不适,以右上腹为著,就诊于当地医院,行相关检查诊断肝占位性病变,未完全缓解。患者为求进一步治疗遂来我院。既往有高血压,糖尿病病史,入院体格检查未见明显异常,未触及腹部肿块及肿大淋巴结。 展开更多
关键词 igg4 igg4相关硬化性胆管炎 胆管癌 肿块型igg4相关硬化性胆管炎 磁共振成像
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自身免疫性肝炎患者血清多反应性IgG水平变化及其临床意义探讨
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作者 张旭晖 张会品 《实用肝脏病杂志》 2026年第2期221-224,共4页
目的探讨自身免疫性肝炎(AIH)患者血清多反应性IgG(pIgG)水平变化及其临床意义,旨在为临床诊疗提供参考依据。方法2022年9月~2024年9月我院诊治的AIH患者48例,均接受肝活检和标准免疫抑制治疗6个月。常规检测血清IgG水平,采用ELISA试剂... 目的探讨自身免疫性肝炎(AIH)患者血清多反应性IgG(pIgG)水平变化及其临床意义,旨在为临床诊疗提供参考依据。方法2022年9月~2024年9月我院诊治的AIH患者48例,均接受肝活检和标准免疫抑制治疗6个月。常规检测血清IgG水平,采用ELISA试剂盒检测并自动计算pIgG水平。结果29例临床重度AIH患者血清ALT、AST、TBIL和pIgG水平分别为(152.8±35.2)U/L、(128.3±32.6)U/L、(73.1±23.5)μmol/L和(83.5±23.2)mg/L,均显著高于19例轻中度患者【分别为(72.5±15.6)U/L、(68.3±16.8)U/L、(27.8±6.3)μmol/L和(45.4±15.8)mg/L,P<0.05】,而两组血清IgG水平比较差异不具有统计学意义(P>0.05);31例肝组织炎症活动度G3/G4患者血清pIgG水平为(84.6±25.0)mg/L,显著高于17例G1/G2患者【(44.5±16.3)mg/L,P<0.05】;在治疗6个月末,38例(79.2%)获得生化学应答完全,获得不完全10例(20.8%);应答完全患者基线血清pIgG水平为(42.0±11.7)mg/L,显著低于应答不完全患者【(81.8±17.2)mg/L,P<0.05】,完全应答与不完全应答组血清IgG水平比较,差异不具有统计学意义(P>0.05)。结论血清pIgG水平可能帮助评估AIH患者疾病活动度和预测治疗应答,是否可作为新型生物标志物应用于临床,值得深入研究。 展开更多
关键词 自身免疫性肝炎 免疫抑制治疗 多反应性igg 治疗
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以占位性病变为主要表现的胃IgG4相关性疾病1例
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作者 卢瑶 游黎虹 +2 位作者 刘睿 王英 朱明华 《临床与实验病理学杂志》 北大核心 2026年第1期130-131,共2页
胃窦小弯侧纤维包块型IgG4相关性疾病(IgG4-related diseases,IgG4-RD)临床表现多样且相对少见,累及脏器众多,常表现为局部肿块形成,影像学检查多疑为占位性肿瘤。IgG4-RD的胃部占位较为罕见。病理诊断和血清学检查是诊断IgG4-RD的金标... 胃窦小弯侧纤维包块型IgG4相关性疾病(IgG4-related diseases,IgG4-RD)临床表现多样且相对少见,累及脏器众多,常表现为局部肿块形成,影像学检查多疑为占位性肿瘤。IgG4-RD的胃部占位较为罕见。病理诊断和血清学检查是诊断IgG4-RD的金标准。病变占位者多采取手术切除为主,术后通过药物辅助治疗。本文报道1例IgG4-RD的临床病理学特征、诊断及鉴别诊断,并复习相关文献,旨在进一步提高对这种罕见病变的认识。 展开更多
关键词 胃肿瘤 igg4相关疾病 病例报道
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新生儿溶血病患儿IgG型ABO血型系统抗体效价及血细胞参数与胆红素、住院时间的关系
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作者 胡文文 陈珂 杨兵 《临床和实验医学杂志》 2026年第2期172-176,共5页
目的探讨新生儿溶血病(HDN)患儿IgG型ABO血型系统抗体效价及血细胞参数与胆红素、住院时间的关系。方法采用回顾性研究,选取2021年2月至2024年8月安徽省阜阳市人民医院收治的120例HDN患儿,分析所有患儿游离试验与放散试验结果,并实施Ig... 目的探讨新生儿溶血病(HDN)患儿IgG型ABO血型系统抗体效价及血细胞参数与胆红素、住院时间的关系。方法采用回顾性研究,选取2021年2月至2024年8月安徽省阜阳市人民医院收治的120例HDN患儿,分析所有患儿游离试验与放散试验结果,并实施IgG型抗体效价测定,收集患儿临床资料。在放散试验中,比较不同IgG型抗体效价患儿红细胞计数、血红蛋白、白蛋白、总胆红素(STB)、非结合胆红素(UCB)水平;采用Spearman或Pearson相关性分析探讨放散试验中IgG型抗体效价、血细胞参数与血清STB、UCB、住院时间之间的关系。结果放散试验HDN阳性率(77.50%)显著高于游离试验(71.25%),差异有统计学意义(P<0.05)。在放散试验中,HDN阳性患儿体内IgG型抗体效价为1∶1~1∶32,其中抗体效价最高为1∶32,抗体效价1∶1占比最高(24.73%);在游离试验中,HDN阳性患儿体内IgG型抗体效价为1∶1~1∶2,其中抗体效价最高为1∶2,抗体效价1∶1占比最高(82.67%)。在放散试验中,不同IgG型抗体效价HDN患儿日龄、住院时间、红细胞计数、血红蛋白、白蛋白及血清STB、UCB水平比较,差异均有统计学意义(P<0.05),随着抗体效价升高,患儿日龄、红细胞计数、血红蛋白、白蛋白均逐渐下降,住院时间及血清STB、UCB水平均逐渐升高,差异均有统计学意义(P<0.05)。Spearman相关性分析结果显示,放散试验中IgG型抗体效价与血清STB、UCB、住院时间均呈正相关(P<0.05)。Pearson相关性分析结果显示,红细胞计数、血红蛋白、白蛋白与血清STB、UCB、住院时间均呈负相关(P<0.05)。结论IgG型ABO血型系统抗体效价及血细胞参数与HDN患儿STB、UCB、住院时间存在显著相关性,有助于评估病情及预后。 展开更多
关键词 新生儿溶血病 血细胞参数 igg型抗体效价 严重程度 预后
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孕妇血清IgG抗A(B)抗体效价积分联合其他血液指标在ABO血型不合新生儿溶血病早期诊断中的应用
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作者 赵德芳 赵晓丽 +3 位作者 朱雪 王二梅 李玲 侯菊玲 《西部医学》 2026年第2期297-301,共5页
目的探讨孕妇血清IgG抗A(B)抗体效价积分联合其他血液指标在ABO血型不合新生儿溶血病(HDN)早期诊断中的应用。方法选取2020年3月-2023年12月在本院分娩的O型高效价足月孕产妇112例为研究对象,孕产妇产前抽取抗凝血检测血清IgG抗A(B)抗... 目的探讨孕妇血清IgG抗A(B)抗体效价积分联合其他血液指标在ABO血型不合新生儿溶血病(HDN)早期诊断中的应用。方法选取2020年3月-2023年12月在本院分娩的O型高效价足月孕产妇112例为研究对象,孕产妇产前抽取抗凝血检测血清IgG抗A(B)抗体效价和其他血液指标[总胆红素(TBil)、平均血小板体积(MPV)、血小板计数(PLT)、中性粒细胞比例(NEUT%)、血红蛋白(Hb)、平均红细胞体积(MCV)、平均红细胞血红蛋白浓度(MCHC)],并抽取新生儿静脉血确定HDN患病情况,依据HDN患病与否分为HDN组(n=60)和非HDN组(n=52),比较两组临床资料、血清IgG抗A(B)抗体效价积分及其他血液指标,受试者工作特征曲线(ROC)分析血清IgG抗A(B)抗体效价积分联合其他血液指标早期诊断ABO血型不合HDN的效能。结果与非HDN组相比较,HDN组孕妇血清IgG抗A(B)抗体效价≤1:64比率更低,≥1∶1024比率更高,血清IgG抗A(B)抗体效价积分更高(均P<0.05)。与非HDN组相比较,HDN组TBil、NEUT%、MCHC水平均更高,Hb水平更低(均P<0.05)。根据ROC曲线下AUC预测价值,孕妇血清IgG抗A(B)抗体效价积分、TBil、NEUT%、MCHC、Hb早期诊断ABO血型不合HDN的AUC分别为0.846、0.819、0.759、0.754、0.742(P<0.05),孕妇血清IgG抗A(B)抗体效价积分联合其他血液指标早期诊断ABO血型不合HDN的AUC为0.964(95%CI:0.929~1.000)(P<0.05)。结论孕妇血清IgG抗A(B)抗体效价积分联合其他血液指标检测具备良好早期诊断ABO血型不合HDN效能,各指标联合评价在产前产检中有重要应用价值。 展开更多
关键词 igg抗A(B)抗体效价 血液指标 早期诊断 ABO血型不合新生儿溶血病
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Study on the effect of preparation method on denitration performance of Co-modified Ce/TiO_(2) catalyst
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作者 YU Chao ZHANG Boya +2 位作者 SHEN Kai HAN Yuxuan ZHANG Yaping 《燃料化学学报(中英文)》 北大核心 2026年第3期79-91,共13页
This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s... This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s low-temperature denitrification activity.After identifying optimal preparation parameters via condition screening,multiple characterization techniques-including BET,XRD,XPS,H_(2)-TPR and in situ DRIFTS-were employed to deeply analyze the catalyst’s physicochemical properties and reaction mechanism.Results demonstrated that compared to the impregnation and co-precipitation methods,the Ce-Co_(0.025)/TiO_(2)-SG catalyst(prepared by the sol-gel method with a Co/Ti mass ratio of 0.025)exhibited significantly superior denitrification activity:NO conversion remained stably above 95%in the 225−350℃ temperature range,and it displayed high N_(2) selectivity.Characterization analysis revealed that abundant surface oxygen vacancies,a high proportion of Ce^(3+) species,and prominent acidic sites collectively contributed to enhancing its low-temperature denitrification performance.This work provides reference value for the development of highly efficient low-temperature denitrification catalysts. 展开更多
关键词 preparation method Co Ce/TiO_(2) low-temperature denitration NH3-SCR
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A New Inversion-free Iterative Method for Solving the Nonlinear Matrix Equation and Its Application in Optimal Control
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作者 GAO Xiangyu XIE Weiwei ZHANG Lina 《应用数学》 北大核心 2026年第1期143-150,共8页
In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to ... In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method. 展开更多
关键词 Nonlinear matrix equation Maximal positive definite solution Inversion-free iterative method Optimal control
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Broadband ground motion simulation and analysis of a near-fault 3D basin-mountain coupling site based on the hybrid method
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作者 Liu Zhongxian Tang Kang +2 位作者 Li Chengcheng Yuan Xiaoming Zhang Hai 《Earthquake Engineering and Engineering Vibration》 2026年第1期87-110,共24页
This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SE... This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SEM),which is used to simulate low-frequency ground motion(f<1 Hz)by incorporating an innovative efficient discontinuous Galerkin(DG)method for grid division to accurately model basin sedimentary layers at reduced costs.It also introduces a comprehensive hybrid source model for high-frequency random scattering and a nonlinear analysis module for basin sedimentary layers.Deterministic outcomes are combined with modified three-dimensional stochastic finite fault method(3D-EXSIM)simulations of high-frequency ground motion(f>1 Hz).A fourth-order Butterworth filter with zero phase shift is employed for time-domain filtering of low-and high-frequency time series at a crossover frequency of 1 Hz,merging the low and high-frequency ground motions into a broadband time series.Taking an Ms 6.8 Luding earthquake,as an example,this hybrid method was used for a rapid and efficient simulation analysis of broadband ground motion in the region.The accuracy and efficiency of this hybrid method were verified through comparisons with actually observed station data and empirical attenuation curves.Deterministic method simulation results revealed the effects of mountainous topography,basin effects,nonlinear effects within the basin’s sedimentary layers,and a coupling interaction between the basin and the mountains.The findings are consistent with similar studies,showing that near-fault sedimentary basins significantly focus and amplify strong ground motion,and the soil’s nonlinear behavior in the basin influences ground motion to varying extents at different distances from the fault.The mountainous topography impacts the basin’s response to ground motion,leading to barrier effects.This research provides a scientific foundation for seismic zoning,urban planning,and seismic design in nearfault mountain basin regions. 展开更多
关键词 hybrid ground motion simulation method spectral element method three-dimensional stochastic finite fault method near-fault basin-mountain coupling effect basin effect nonlinear effect
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Establishment of a Determination Method for Fruit Texture in Chieh-qua Using Texture Analyzer
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作者 Ying WANG Xuan DU Na LIU 《Agricultural Biotechnology》 2026年第1期54-59,共6页
[Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and pun... [Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and puncture,the index data of the fruit were obtained by setting different trigger forces,deformation levels,test speeds,as well as puncture speeds and puncture depths.The data included TPA hardness,adhesiveness,springiness,cohesiveness,gumminess,chewiness,resilience,as well as skin hardness,skin toughness,flesh hardness,fracturability,and compactness.[Results]Different deformation levels had a significant impact on all parameters.Hardness,adhesiveness,gumminess and chewiness showed a trend of first increasing and then decreasing with the deformation level increasing.When the deformation level was 30%,the adhesiveness,gumminess and chewiness reached their maximum values.When the deformation level was 50%,TPA hardness reached its maximum.When the compression speed was 3 mm/s,the measured values of TPA hardness,adhesiveness,chewiness,and resilience were at their maximums.The skin hardness varied significantly under different trigger forces.When the trigger force was 15 g,the skin hardness reached a maximum value of 944.63 g,and the skin toughness,flesh hardness,fracturability,and compactness also reach their maximum values respectively.When the puncture depth was 12 mm,the flesh hardness and skin toughness reached their maximums of 682.51 g and 1.82 mm,respectively.In the TPA mode,the flesh hardness of chieh-qua showed an extremely significant negative correlation with springiness,cohesiveness,and resilience(P<0.01).The fruit fracturability detected by puncture had an extremely significant positive correlation with compactness(P<0.01).[Conclusions]The evaluation method for measuring chieh-qua texture by combining TPA and the puncture mode could accurately and quantitatively reflect the differences in the flesh texture quality of chieh-qua.The optimal parameters for texture measurement of chieh-qua fruit were determined as a 15 g trigger force with 50%deformation and a 3 mm/s compression speed in TPA mode,and a 15 g trigger force with a 12 mm puncture depth in puncture mode.Puncture speed was found to have no significant effect on the texture indices of chieh-qua. 展开更多
关键词 CHIEH-QUA Texture analyzer Texture quality Determination method
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A novel scaling method for the elastic ring supporting structure of an aero-engine rotor system: analytical and experimental investigations
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作者 Lei LI Tianyue MA +4 位作者 Zhong LUO Dongwu GAO Xiangdong GE Hui MA Shibin WANG 《Applied Mathematics and Mechanics(English Edition)》 2026年第1期1-18,共18页
The testing of large structures is limited by high costs and long cycles, making scaling methods an attractive solution. However, the scaling process of elastic rings introduces complexities in multi-parameter geometr... The testing of large structures is limited by high costs and long cycles, making scaling methods an attractive solution. However, the scaling process of elastic rings introduces complexities in multi-parameter geometric distortions, leading to a diminution in the predictive accuracy of the distorted similitude. To address this challenge, this study formulates a novel set of scaling laws, tailored to account for the intricate geometric distortions associated with elastic rings. The proposed scaling laws are formulated based on the intrinsic deformation characteristics of elastic rings, rather than the traditional systemic governing equations. Numerical and experimental cases are conducted to assess the efficacy and precision of the proposed scaling laws, and the obtained results are compared with those achieved by traditional methods. The outcomes demonstrate that the scaling laws put forth by this study significantly enhance the predictive capabilities for deformations of elastic rings. 展开更多
关键词 rotor system AERO-ENGINE elastic ring scaling method supporting structure
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Multiphysics Implicit Coupling Method for Fluid,Particles,and Large-Deformation Structures
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作者 Xiangxiang Wang Hualong Xie +3 位作者 Yue Yu Min Li Yubin Wang Fei Xing 《Computer Modeling in Engineering & Sciences》 2026年第2期367-401,共35页
This study presents an implicit multiphysics coupling method integrating Computational Fluid Dynamics(CFD),the Multiphase Particle-in-Cell(MPPIC)model,and the Finite Element Method(FEM),implemented with OpenFOAM,Calcu... This study presents an implicit multiphysics coupling method integrating Computational Fluid Dynamics(CFD),the Multiphase Particle-in-Cell(MPPIC)model,and the Finite Element Method(FEM),implemented with OpenFOAM,CalculiX,and preCICE to simulate fluid-particle-structure interactions with large deformations.Mesh motion in the fluid field is handled using the radial basis function(RBF)method.The particle phase is modeled by MPPIC,where fluid-particle interaction is described through momentum exchange,and inter-particle collisions are characterized by collision stress.The structural field is solved by nonlinear FEM to capture large deformations induced by geometric nonlinearity.Coupling among fields is realized through a partitioned,parallel,and non-intrusive iterative strategy,ensuring stable transfer and convergence of interface forces and displacements.Notably,the influence of particles on the structure is not direct but mediated by the fluid,while structural motion directly affects particle dynamics.The results demonstrate that the proposed approach effectively captures multiphysics interaction processes and provides a valuable reference for numerical modeling of coupled fluid-particle-structure systems. 展开更多
关键词 Fluid-particle-structure interaction large deformation partitioned method non-intrusive coupling
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Healthcare professionals’perspectives on disclosure of diagnosis and related issues in childhood cancer:A mixed methods systematic review
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作者 Run Xie Xiaoyan Huang +4 位作者 Yiran Du Ying Gu Qiongfang Kang Hongsheng Wang Daqian Zhu 《International Journal of Nursing Sciences》 2026年第1期96-104,I0006,共10页
Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of... Objectives This review aimed to systematically synthesize the available research on the disclosure of diagnosis and related issues in childhood cancer from the perspectives of healthcare professionals,with the goal of informing the optimization of disclosure processes and meeting the communication needs of affected families.Methods In accordance with the Joanna Briggs Institute(JBI)methodology for mixed methods systematic reviews,the convergent segregated approach was used in this review.Articles were retrieved from 11 databases,including PubMed,Web of Science,CINAHL,CENTRAL,Embase,Ovid/Medline,PsycINFO,PsycArticles,Scopus,ERIC,and China National Knowledge Infrastructure(CNKI).The quality of the selected articles was assessed using the Mixed Method Appraisal Tool(MMAT).The review protocol was registered on PROSPERO(CRD42024542746).Results A total of 21 studies from 10 countries were included.Their methodological quality was generally medium to high,with MMAT scores ranging from 60%to 100%.The synthesis yielded three core themes:1)the spectrum of professional and societal attitudes toward disclosure;2)the dynamic practices of navigating disclosure amid uncertainty,including timing and environment,stakeholders,and content of disclosure;and 3)factors influencing disclosure,including children’s,parental,healthcare professionals’,and socio-cultural factors.Conclusions This review synthesized the perspectives and experiences of healthcare professionals regarding disclosure in childhood cancer,highlighting the complexity and multidimensional nature of this process in clinical practice.Future research should further investigate the experiences and needs of children and their parents,explore cultural variations in disclosure practices,develop context-appropriate assessment tools,and construct multidimensional intervention strategies to enhance the humanistic care and professional effectiveness of the disclosure process. 展开更多
关键词 Communication CANCER DISCLOSURE Healthcare professionals Mixed methods PEDIATRIC Systematic review
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Investigation of equivalent strength parameters of soil-rock mixture using numerical manifold method
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作者 Junfeng Li Yongtao Yang +2 位作者 Yang Xia Hong Zheng Shuilin Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期637-650,共14页
As binary geological media,soil-rock mixtures(SRMs)exhibit a distinct gradational composition,leading to their unique mechanical behaviors.To appraise the stability of SRM slopes,it is essential to determine equivalen... As binary geological media,soil-rock mixtures(SRMs)exhibit a distinct gradational composition,leading to their unique mechanical behaviors.To appraise the stability of SRM slopes,it is essential to determine equivalent parameters of SRMs,which are typically obtained through experimental and numerical methods.In contrasted to other numerical methods,the numerical manifold method(NMM)is more effective in addressing SRM problems.This is because the high-precision regular mathematical meshes in NMM can be used without aligning with the soil-rock interfaces and boundaries of SRMs.In the current research,the equivalent strength parameters of SRMs,i.e.the equivalent cohesion ce and internal friction angleϕ_(e),are determined using NMM.Initially,an NMM triaxial numerical model is established and validated based on triaxial experiments.Subsequently,the soil and rock parameters are derived through parameter inversion.Moreover,the impacts of rock content,size,shape and rock blocks'major-axis orientation on ce andϕ_(e) of SRMs are thoroughly examined using the NMM triaxial numerical model.Additionally,a fitting function is proposed to linkϕ_(e) to the rock content and size of SRMs.When other influencing factors are fixed,the above fitting model leads to the following conclusions:(1)the predictedϕ_(e) of SRMs increase with the increase of rock content;and(2)SRM samples with smaller rocks display a higher predictedϕ_(e). 展开更多
关键词 Soil-rock mixtures Equivalent strength parameters Numerical manifold method
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Subtitle Translation Methods of The Good Wife From Functional Equivalence Perspective
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作者 WANG Ya-kun BAO De-wang 《Journal of Literature and Art Studies》 2026年第1期26-30,共5页
The Good Wife is an American TV series that focuses on women’s independence,politics,and law.The drama has been remade in China,Japan,and South Korea.This research aims to use Nida’s Functional Equivalence Theory to... The Good Wife is an American TV series that focuses on women’s independence,politics,and law.The drama has been remade in China,Japan,and South Korea.This research aims to use Nida’s Functional Equivalence Theory to analyze the methods of its English-to-Chinese subtitle translation by considering social,cultural,and historic backgrounds between China and America.After data collection and case analysis,the study found that:(1)Five major translation methods are adopted in the subtitle translation of The Good Wife.They are free translation,variation,literal translation,addition,and omission.Among them,free translation is the most frequently used,while omission is used least.(2)The subtitle translation of films and TV series is limited by time and space restrictions,social-cultural differences,and other factors.When translating,translators should try to use humorous words,euphemism,intonation,and other ways,and combine different methods such as literal translation,free translation,variation,addition,omission,and other methods to seek equivalence both in the meaning and function of subtitles under the guidance of Functional Equivalence Theory. 展开更多
关键词 subtitle translation Functional Equivalence Theory The Good Wife translation methods
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