We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and...We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.展开更多
We study the relation between Type Ia Supernovae （SNe Ia） and properties of their host galaxies using a large sample with low redshift. By examining the Hubble residuals of the entire sample from the best-fit cosmol...We study the relation between Type Ia Supernovae （SNe Ia） and properties of their host galaxies using a large sample with low redshift. By examining the Hubble residuals of the entire sample from the best-fit cosmology, we show that SNe Ia in passive hosts are brighter than those in star-forming hosts after light curve correction at the 2. 1σ confidence level. We find that SNe Ia in high luminosity hosts are brighter after light-curve correction at the 〉 3σ confidence level. We also find that SNe Ia in large galaxies are brighter after light-curve correction at the ≥2σ confidence level. We demonstrate that the residuals depend linearly on host luminosity at a confidence of 4or or host size at a confidence of 3.3σ.展开更多
BACKGROUND Proximal humeral fractures represent the third most common observed osteoporotic fracture;the treatment in three and four-part proximal humeral fractures in patients over 65 years is still controversial.Amo...BACKGROUND Proximal humeral fractures represent the third most common observed osteoporotic fracture;the treatment in three and four-part proximal humeral fractures in patients over 65 years is still controversial.Among the treatments described in literature,open reduction and internal fixation(O.R.I.F)and reverse shoulder arthroplasty(RSA)are gaining an increasing popularity.AIM To investigate the correct treatment for three and four-part proximal humeral fractures according to psychological aspects.METHODS It was conducted a prospective study with a series of 63 patients treated with O.R.I.F.(group A)and with RSA(group B)for three and four-part proximal humeral fractures according to Neer classification system.A conservative treatment group,as control,was finally introduced.One independent observer performed clinical and a psychological evaluation at one(T0),six(T1)and twelve months(T2)postoperatively.The Constant’s score and The Disabilities of the Arm,Shoulder and Hand(DASH score)were used for clinical evaluation,while General Anxiety Disorder-7(GAD-7)and Caregiver Strain Scale(CSS)were used for psychological evaluation.RESULTS At one month follow up in group A the mean values were DASH score 50.8,Constant score 36.1,GAD-7 score 5.4,CSS 5.0.For the group B,the average values at T0 were:DASH score 54.6,Constant score 32.0;GAD-7 score 6.4,CSS 6.2.At six months in group A the average values were DASH score 42.1,Constant score 47.3,GAD-7 score 4.3,CSS 3.9.For the group B,the average values at T1 were:DASH score 39.1,Constant score 43.2,GAD-7 score 5.7,CSS 5.5.At twelve months in the group A,the mean values were DASH score 32.8,Constant score 60.0,GAD-7 score 3.2,CSS 3.1.For the group B shown these mean values:DASH score 33.6,Constant score 52.9,GAD-7 score 4.3,CSS 4.5.We demonstrated a better clinical and psychological outcome at T2 in the group treated with osteosynthesis compared to the group treated with arthroplasty(Constant P=0.049,GAD-7 P=0.012 and CSS P=0.005).A better clinical and psychological outcome emerged in control group at T2 comparing with surgical group(DASH score P=0.014,Constant score P<0.001,GAD-7 P=0.002 and CSS P=0.001).CONCLUSION Both open osteosynthesis and reverse shoulder arthroplasty are valid treatments for proximal humeral fractures.According to the best osteosynthesis results the authors suggested to perform a psychological analysis for each patient in order to choose the appropriate treatment.展开更多
Supernovae of type Ia (SNe Ia) are confirmed to be the best distance indicators to derive the cosmic expansion rate. The dispersion of their peak luminosity at optical bands (BVI) is approximate to 0.13 mag, after ta...Supernovae of type Ia (SNe Ia) are confirmed to be the best distance indicators to derive the cosmic expansion rate. The dispersion of their peak luminosity at optical bands (BVI) is approximate to 0.13 mag, after taking into account the effects of the second parameters (i.e., the Antial decline rate m15(B) and (B - V) color at maximum light). The local calibrations from HST indicate an absolute magnitude of 19.48 ± 0.08mag (in V band) for SNe Ia in spiral galaxies. The current expansion rate, Ho, is found to be 63.6 ± 1.8 (random) ±5.7 (systematic) kms-1 Mpc-1. This Value will decrease by 3% when the metallicity effect on the cepheid distances is considered. In addition, a marginal local outward flow of 4.0 ± 4.5% within the velocity-distance of 7000 km s-1 can be inferred from SNe Ia for the Einstein-de Sitter universe; however, this outward flow is only 2.2 ± 4.4% for an accelerating expansion universe (which is supported by high-z SNe Ia).展开更多
We propose a consistency test for some recent X-ray gas mass fraction （fgas） measurements in galaxy clusters, using the cosmic distance-duality relation, Ttneory = DL（1 ＋ Z）-2/DA, with luminosity distance （DL） ...We propose a consistency test for some recent X-ray gas mass fraction （fgas） measurements in galaxy clusters, using the cosmic distance-duality relation, Ttneory = DL（1 ＋ Z）-2/DA, with luminosity distance （DL） data from the Union2 compilation of type Ia supernovae. We set Z/theory = 1, instead of assigning any red- shift parameterizations to it, and constrain the cosmological information preferred by fga8 data along with supernova observations. We adopt a new binning method in the reduction of the Union2 data, in order to minimize the statistical errors. Four data sets of X-ray gas mass fraction, which are reported by Allen et al. （two samples）, LaRoque et al. and Ettori et al., are analyzed in detail in the context of two theoretical models of fgas. The results from the analysis of Alien et al.＇s samples demonstrate the feasibility of our method. It is found that the preferred cosmology by LaRoque et al.＇s sample is consistent with its reference cosmology within the 1σ confidence level. However, for Ettori et al.＇s fgas sample, the inconsistency can reach more than a 3σ confidence level and this dataset shows special preference to an ΩA = 0 cosmology.展开更多
文摘We investigated the relationship between health-related quality of life (HRQOL) and psychological distress in intensive care unit (ICU) survivors 12 months after ICU discharge. The purpose of this study, conducted and completed before the onset of the COVID-19 pandemic, was to find correlations among psychiatric symptoms detected by a screening tool as the General Health Questionnaire-28 (GHQ-28) and the different domains of HRQOL measured with the SF-36 health survey (SF-36), in order to identify ICU survivors with Post-Intensive Care Syndrome (PICS) who need a specific psychiatric intervention to improve their HRQOL. Among 298 ICU survivors who stayed in the ICU for at least 72 hours, 48 patients were enrolled one year after discharge undergoing a clinical interview to assess their functional impairment (Barthel index), mental health (GHQ-28), and health-related quality of life (SF-36). 19% of those subjects had a GHQ-28 ≥ 5 and were identified as “psychiatric cases”, and they were older and experienced a greater impairment in HRQOL. Anxiety, insomnia, and depressive symptoms seemed to be particularly involved in the impairment of HRQOL. A negative correlation between GHQ-28 total scores and subscales and SF-36 subscales was found. Our findings highlighted that psychological distress in ICU survivors may negatively impact physical health recovery and quality of life;conversely, physical impairment and functional disability may trigger the onset of psychiatric symptoms after discharge. The present study is firstly to investigate the correlations between HRQOL and psychological distress in ICU survivors through the GHQ-28, and then affirms the need to carry out follow-up checks for psychiatric symptoms in ICU survivors.
基金financial support from the National Basic Research Program of China (973 Program 2009CB824800)+2 种基金the National Natural Science Foundation of China (Grant Nos. 11133006 11163006 and 11173054)the Policy Research Program of Chinese Academy of Sciences (KJCX2-YW-T24)
文摘We study the relation between Type Ia Supernovae （SNe Ia） and properties of their host galaxies using a large sample with low redshift. By examining the Hubble residuals of the entire sample from the best-fit cosmology, we show that SNe Ia in passive hosts are brighter than those in star-forming hosts after light curve correction at the 2. 1σ confidence level. We find that SNe Ia in high luminosity hosts are brighter after light-curve correction at the 〉 3σ confidence level. We also find that SNe Ia in large galaxies are brighter after light-curve correction at the ≥2σ confidence level. We demonstrate that the residuals depend linearly on host luminosity at a confidence of 4or or host size at a confidence of 3.3σ.
文摘BACKGROUND Proximal humeral fractures represent the third most common observed osteoporotic fracture;the treatment in three and four-part proximal humeral fractures in patients over 65 years is still controversial.Among the treatments described in literature,open reduction and internal fixation(O.R.I.F)and reverse shoulder arthroplasty(RSA)are gaining an increasing popularity.AIM To investigate the correct treatment for three and four-part proximal humeral fractures according to psychological aspects.METHODS It was conducted a prospective study with a series of 63 patients treated with O.R.I.F.(group A)and with RSA(group B)for three and four-part proximal humeral fractures according to Neer classification system.A conservative treatment group,as control,was finally introduced.One independent observer performed clinical and a psychological evaluation at one(T0),six(T1)and twelve months(T2)postoperatively.The Constant’s score and The Disabilities of the Arm,Shoulder and Hand(DASH score)were used for clinical evaluation,while General Anxiety Disorder-7(GAD-7)and Caregiver Strain Scale(CSS)were used for psychological evaluation.RESULTS At one month follow up in group A the mean values were DASH score 50.8,Constant score 36.1,GAD-7 score 5.4,CSS 5.0.For the group B,the average values at T0 were:DASH score 54.6,Constant score 32.0;GAD-7 score 6.4,CSS 6.2.At six months in group A the average values were DASH score 42.1,Constant score 47.3,GAD-7 score 4.3,CSS 3.9.For the group B,the average values at T1 were:DASH score 39.1,Constant score 43.2,GAD-7 score 5.7,CSS 5.5.At twelve months in the group A,the mean values were DASH score 32.8,Constant score 60.0,GAD-7 score 3.2,CSS 3.1.For the group B shown these mean values:DASH score 33.6,Constant score 52.9,GAD-7 score 4.3,CSS 4.5.We demonstrated a better clinical and psychological outcome at T2 in the group treated with osteosynthesis compared to the group treated with arthroplasty(Constant P=0.049,GAD-7 P=0.012 and CSS P=0.005).A better clinical and psychological outcome emerged in control group at T2 comparing with surgical group(DASH score P=0.014,Constant score P<0.001,GAD-7 P=0.002 and CSS P=0.001).CONCLUSION Both open osteosynthesis and reverse shoulder arthroplasty are valid treatments for proximal humeral fractures.According to the best osteosynthesis results the authors suggested to perform a psychological analysis for each patient in order to choose the appropriate treatment.
基金the National Natural Science Foundation of China(19733002) Project of“973”(G19990750401)
文摘Supernovae of type Ia (SNe Ia) are confirmed to be the best distance indicators to derive the cosmic expansion rate. The dispersion of their peak luminosity at optical bands (BVI) is approximate to 0.13 mag, after taking into account the effects of the second parameters (i.e., the Antial decline rate m15(B) and (B - V) color at maximum light). The local calibrations from HST indicate an absolute magnitude of 19.48 ± 0.08mag (in V band) for SNe Ia in spiral galaxies. The current expansion rate, Ho, is found to be 63.6 ± 1.8 (random) ±5.7 (systematic) kms-1 Mpc-1. This Value will decrease by 3% when the metallicity effect on the cepheid distances is considered. In addition, a marginal local outward flow of 4.0 ± 4.5% within the velocity-distance of 7000 km s-1 can be inferred from SNe Ia for the Einstein-de Sitter universe; however, this outward flow is only 2.2 ± 4.4% for an accelerating expansion universe (which is supported by high-z SNe Ia).
基金supported by the National Basic Research Program of China (973 program Grant Nos. 2009CB824800 and 2012CB821804)+1 种基金the National Natural Science Foundation of China (Grant Nos. 11033002 and 11173006)the Fundamental Research Funds for the Central Universities
文摘We propose a consistency test for some recent X-ray gas mass fraction （fgas） measurements in galaxy clusters, using the cosmic distance-duality relation, Ttneory = DL（1 ＋ Z）-2/DA, with luminosity distance （DL） data from the Union2 compilation of type Ia supernovae. We set Z/theory = 1, instead of assigning any red- shift parameterizations to it, and constrain the cosmological information preferred by fga8 data along with supernova observations. We adopt a new binning method in the reduction of the Union2 data, in order to minimize the statistical errors. Four data sets of X-ray gas mass fraction, which are reported by Allen et al. （two samples）, LaRoque et al. and Ettori et al., are analyzed in detail in the context of two theoretical models of fgas. The results from the analysis of Alien et al.＇s samples demonstrate the feasibility of our method. It is found that the preferred cosmology by LaRoque et al.＇s sample is consistent with its reference cosmology within the 1σ confidence level. However, for Ettori et al.＇s fgas sample, the inconsistency can reach more than a 3σ confidence level and this dataset shows special preference to an ΩA = 0 cosmology.
