With the continuous advancement of the New Engineering Education initiative,universities are raising the standards for cultivating engineering talents.C Programming Language,as a core course for computer science and r...With the continuous advancement of the New Engineering Education initiative,universities are raising the standards for cultivating engineering talents.C Programming Language,as a core course for computer science and related majors,plays a fundamental role in developing logical thinking,programming skills,and engineering practice.However,problems such as outdated content,weak practical connections,and single assessment methods still exist in current teaching,which affects both learning outcomes and students’skill development.Based on the outcome-based education(OBE)approach and supported by AI-assisted teaching tools,this paper proposes a reform plan focusing on teaching content,instructional methods,and evaluation systems.The goal is to enhance students’overall abilities and practical innovation skills,and to align the course more closely with modern industry needs.展开更多
Beryllium(^(9)Be)serves as a crucial neutron multiplier and reflection material,being extensively employed in the nuclear industry.The evaluated nuclear data are utilized in the design of the nuclear devices.Following...Beryllium(^(9)Be)serves as a crucial neutron multiplier and reflection material,being extensively employed in the nuclear industry.The evaluated nuclear data are utilized in the design of the nuclear devices.Following the interaction between neutrons and^(9)Be,all neutrons generated stem from the^(9)Be(n,2n)^(8)Be reaction channel,except for the elastic scattering reaction channel.Nevertheless,the data of the outgoing neutron double differential cross section of the reaction channel provided by the latest internationally evaluated libraries still exhibit considerable discrepancies.A shielding integral experiment based on slab^(9)Be samples with measurements of neutron spectra leaked from different angles is an effective approach to verify the double differential cross-section data.Hence,in this study,a shielding integral experiment of^(9)Be samples of different thicknesses was conducted using a nanosecond pulsed deuterium-tritium neutron source established by the China Institute of Atomic Energy.The neutron time-of-flight spectra of three thicknesses(4.4 cm,8.8 cm,and 13.2 cm)and six angles(47°,58°,73°,107°,122°,and 133°)were measured by the neutron time-of-flight method,and 18 sets of experimental data were obtained.Additionally,the MCNP-4C program was used to obtain the simulated results of the leakage neutron spectra using the evaluated nuclear data of^(9)Be from the CENDL-3.2,ENDF/B-Ⅷ.0,JENDL-5,and JEFF-3.3 libraries.The simulated results of the leakage neutron spectra were compared with the experimental results,and the results showed that in the elastic scattering energy region,the simulated results from the CENDL-3.2,ENDF/B-Ⅷ.0,and JENDL-5 libraries were slightly higher at small angles and slightly lower at large angles.In the(n,2n)energy region,the simulated results from the CENDL-3.2 library were significantly different from the experimental results in terms of spectral shape,and the simulated results from the ENDF/B-Ⅷ.0 and the JENDL-5 libraries were in good agreement with the experimental results at small angles but low at large angles.The simulated results from the JEFF-3.3 library showed serious underestimation at all angles.展开更多
Chronic hepatitis C virus(HCV) infection is a public health issue that often progresses to life-threatening complications, including liver cirrhosis, fibrosis, and hepatocellular carcinoma. Impaired immune responses t...Chronic hepatitis C virus(HCV) infection is a public health issue that often progresses to life-threatening complications, including liver cirrhosis, fibrosis, and hepatocellular carcinoma. Impaired immune responses to HCV are key features of chronic HCV infection. Therefore, intervention strategies usually involve enhancing the immune responses against HCV. Cytotoxic CD8+ T lymphocytes(CTLs) play a critical role in the control of HCV infection. However, their cytolytic function can be impaired by the expression of co-inhibitory molecules. Programmed death-1(PD-1) receptor and its ligand PD-L1 function in a T cell co-inhibitory pathway, which either blocks the function of CTLs or the differentiation of CD8+ T cells. During chronic HCV infection, the immune inhibitory receptor PD-1 is upregulated on dysfunctional HCV-specific CD8+ T cells. As such, blockade of the PD-1/PD-L1 pathway in these CD8+ T cells might restore their functional capabilities. Indeed, clinical trials using therapies to block this pathway have shown promise in the fostering of anti-HCV immunity. Understanding how chronic HCV infection induces upregulation of PD-1 on HCV specific T cells and how the PD-1/PD-L1 interaction develops HCV specific T cell dysfunction will accelerate the development of an efficacious prophylactic and therapeutic vaccination against chronic HCV infections, which will significantly improve HCV treatments and patient survival. In this review, we discuss the relationship between PD-1 expression and clinical responses and the potential use of PD-1 blockade for anti-HCV therapy.展开更多
In the capital city of Baghdad, The surface water suffering from effect of conservative pollutants. Baghdad city has two rivers, the main river Tigris River and Diyala River in boundary of Baghdad city (Jassir Diyala)...In the capital city of Baghdad, The surface water suffering from effect of conservative pollutants. Baghdad city has two rivers, the main river Tigris River and Diyala River in boundary of Baghdad city (Jassir Diyala) eastern of Baghdad. The present study deals with the evaluation of water quality of Tigris River within Baghdad. In the case of Tigris River the concentrations of TH, TDS, PO4 and SO4 were found to lie outside the acceptable range of WHO standards by using WQI analysis and C++ program.展开更多
Matlab has a high performance at engineering calculation.C# is good at interface development.Combining their advantages together,hybrid programming with Matlab and C # will help to improve the reliability analysis sof...Matlab has a high performance at engineering calculation.C# is good at interface development.Combining their advantages together,hybrid programming with Matlab and C # will help to improve the reliability analysis software efficiency and accuracy significantly.Procedures of hybrid programming with Matlab and C# in reliability analysis software are introduced in this paper.Finally a mathematical problem is tested to verify the feasibility of this programming method.展开更多
Fast-growing and High-yielding Forests Base Construction Program is the only industrialization program of six key forestry programs. The main construction content is to plant 13.33 million hm fast-growing and high-yie...Fast-growing and High-yielding Forests Base Construction Program is the only industrialization program of six key forestry programs. The main construction content is to plant 13.33 million hm fast-growing and high-yielding plantation in 18 provinces in China. According to the program planning and growth of different tree species, the biomass of this program is evaluated and the C sequestration is assessed in this paper. In the program period, the biomass of the program will reach 3.703 6×109 t, and the C storage will get 1.851 8×109 t. The program will have a great effect on raising the C pool function of forest vegetation.展开更多
基金funded by Xinjiang Natural Science Foundation of China(2023D01C52)University Key Project(2023YSZD004).
文摘With the continuous advancement of the New Engineering Education initiative,universities are raising the standards for cultivating engineering talents.C Programming Language,as a core course for computer science and related majors,plays a fundamental role in developing logical thinking,programming skills,and engineering practice.However,problems such as outdated content,weak practical connections,and single assessment methods still exist in current teaching,which affects both learning outcomes and students’skill development.Based on the outcome-based education(OBE)approach and supported by AI-assisted teaching tools,this paper proposes a reform plan focusing on teaching content,instructional methods,and evaluation systems.The goal is to enhance students’overall abilities and practical innovation skills,and to align the course more closely with modern industry needs.
基金supported by the National Natural Science Foundation of China(Nos.11775311,U2167203,U2067205 and 12075105)Research and development project of China National Nuclear Corporation(FD010241222552)+2 种基金Continuous-Support Basic Scientific Research Project(BJ010261223282)Major Science and Technology Projects of Gansu Province(22ZD6GB020)Fundamental Research Funds for the Central Universities(lzujbky-2024-jdzx10)。
文摘Beryllium(^(9)Be)serves as a crucial neutron multiplier and reflection material,being extensively employed in the nuclear industry.The evaluated nuclear data are utilized in the design of the nuclear devices.Following the interaction between neutrons and^(9)Be,all neutrons generated stem from the^(9)Be(n,2n)^(8)Be reaction channel,except for the elastic scattering reaction channel.Nevertheless,the data of the outgoing neutron double differential cross section of the reaction channel provided by the latest internationally evaluated libraries still exhibit considerable discrepancies.A shielding integral experiment based on slab^(9)Be samples with measurements of neutron spectra leaked from different angles is an effective approach to verify the double differential cross-section data.Hence,in this study,a shielding integral experiment of^(9)Be samples of different thicknesses was conducted using a nanosecond pulsed deuterium-tritium neutron source established by the China Institute of Atomic Energy.The neutron time-of-flight spectra of three thicknesses(4.4 cm,8.8 cm,and 13.2 cm)and six angles(47°,58°,73°,107°,122°,and 133°)were measured by the neutron time-of-flight method,and 18 sets of experimental data were obtained.Additionally,the MCNP-4C program was used to obtain the simulated results of the leakage neutron spectra using the evaluated nuclear data of^(9)Be from the CENDL-3.2,ENDF/B-Ⅷ.0,JENDL-5,and JEFF-3.3 libraries.The simulated results of the leakage neutron spectra were compared with the experimental results,and the results showed that in the elastic scattering energy region,the simulated results from the CENDL-3.2,ENDF/B-Ⅷ.0,and JENDL-5 libraries were slightly higher at small angles and slightly lower at large angles.In the(n,2n)energy region,the simulated results from the CENDL-3.2 library were significantly different from the experimental results in terms of spectral shape,and the simulated results from the ENDF/B-Ⅷ.0 and the JENDL-5 libraries were in good agreement with the experimental results at small angles but low at large angles.The simulated results from the JEFF-3.3 library showed serious underestimation at all angles.
基金Supported by Science and Technology Development Fund(STDFgrants No.1469 and No.5245)Tanta University Fund,Egypt to Mohamed L Salem,the Principal investigator of these projects
文摘Chronic hepatitis C virus(HCV) infection is a public health issue that often progresses to life-threatening complications, including liver cirrhosis, fibrosis, and hepatocellular carcinoma. Impaired immune responses to HCV are key features of chronic HCV infection. Therefore, intervention strategies usually involve enhancing the immune responses against HCV. Cytotoxic CD8+ T lymphocytes(CTLs) play a critical role in the control of HCV infection. However, their cytolytic function can be impaired by the expression of co-inhibitory molecules. Programmed death-1(PD-1) receptor and its ligand PD-L1 function in a T cell co-inhibitory pathway, which either blocks the function of CTLs or the differentiation of CD8+ T cells. During chronic HCV infection, the immune inhibitory receptor PD-1 is upregulated on dysfunctional HCV-specific CD8+ T cells. As such, blockade of the PD-1/PD-L1 pathway in these CD8+ T cells might restore their functional capabilities. Indeed, clinical trials using therapies to block this pathway have shown promise in the fostering of anti-HCV immunity. Understanding how chronic HCV infection induces upregulation of PD-1 on HCV specific T cells and how the PD-1/PD-L1 interaction develops HCV specific T cell dysfunction will accelerate the development of an efficacious prophylactic and therapeutic vaccination against chronic HCV infections, which will significantly improve HCV treatments and patient survival. In this review, we discuss the relationship between PD-1 expression and clinical responses and the potential use of PD-1 blockade for anti-HCV therapy.
文摘In the capital city of Baghdad, The surface water suffering from effect of conservative pollutants. Baghdad city has two rivers, the main river Tigris River and Diyala River in boundary of Baghdad city (Jassir Diyala) eastern of Baghdad. The present study deals with the evaluation of water quality of Tigris River within Baghdad. In the case of Tigris River the concentrations of TH, TDS, PO4 and SO4 were found to lie outside the acceptable range of WHO standards by using WQI analysis and C++ program.
文摘Matlab has a high performance at engineering calculation.C# is good at interface development.Combining their advantages together,hybrid programming with Matlab and C # will help to improve the reliability analysis software efficiency and accuracy significantly.Procedures of hybrid programming with Matlab and C# in reliability analysis software are introduced in this paper.Finally a mathematical problem is tested to verify the feasibility of this programming method.
文摘Fast-growing and High-yielding Forests Base Construction Program is the only industrialization program of six key forestry programs. The main construction content is to plant 13.33 million hm fast-growing and high-yielding plantation in 18 provinces in China. According to the program planning and growth of different tree species, the biomass of this program is evaluated and the C sequestration is assessed in this paper. In the program period, the biomass of the program will reach 3.703 6×109 t, and the C storage will get 1.851 8×109 t. The program will have a great effect on raising the C pool function of forest vegetation.
