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基于AHP-CRITIC混合加权法结合Box-Behnken响应面法优化桂附颗粒成型工艺
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作者 张庆莲 许曾 +2 位作者 皮凤娟 朱光林 黄娟 《中国药业》 2026年第6期66-71,共6页
目的优选桂附颗粒的成型工艺。方法在单因素试验基础上结合Box-Behnken响应面法,以辅药比、润湿剂(乙醇)体积分数、液料比为考察因素,以成型率、休止角、吸湿率的综合评分为评价指标,采用层次分析法(AHP)-基于指标相关性的权重确定方法(... 目的优选桂附颗粒的成型工艺。方法在单因素试验基础上结合Box-Behnken响应面法,以辅药比、润湿剂(乙醇)体积分数、液料比为考察因素,以成型率、休止角、吸湿率的综合评分为评价指标,采用层次分析法(AHP)-基于指标相关性的权重确定方法(CRITIC)混合加权法确定评价指标权重系数,优选最佳工艺并验证。结果成型率、休止角、吸湿率的权重系数分别为0.5453,0.2931,0.1616。优选的成型工艺为干浸膏适量,选择糊精为辅料,采用湿法制粒,在80℃下干燥3 h,辅药比为1.5∶1(m/m),乙醇体积分数为80%,液料比为20%;乙醇体积分数和液料比对综合评分有显著影响(P<0.05)。按最佳工艺制备3批样品,平均综合评分为82.66分,RSD为1.58%,与预测值(84.25分)的偏差为1.89%。结论优选的成型工艺合理可行,可为桂附颗粒产业化生产及应用提供参考。 展开更多
关键词 AHP-CRITIC混合加权法 box-behnken响应面法 桂附颗粒 成型工艺
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AHP-熵权法结合Box-Behnken设计-响应面法优选建昌帮酒润蜜糠炒白芍炮制工艺
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作者 叶喜德 卜俊文 +4 位作者 邵明国 黄艺 钟凌云 梁冬梅 彭玲珍 《药学前沿》 2026年第2期201-210,共10页
目的基于白芍的主要成分,结合层次分析法-熵权法复合评价,优选建昌帮酒润蜜糠炒白芍炮制工艺。方法以芍药苷、芍药内酯苷、羟基芍药苷、水溶性浸出物及醇溶性浸出物含量的综合评分为指标,采用单因素试验和Box-Behnken响应面法,考察黄酒... 目的基于白芍的主要成分,结合层次分析法-熵权法复合评价,优选建昌帮酒润蜜糠炒白芍炮制工艺。方法以芍药苷、芍药内酯苷、羟基芍药苷、水溶性浸出物及醇溶性浸出物含量的综合评分为指标,采用单因素试验和Box-Behnken响应面法,考察黄酒用量、炒制时间、炒制温度、蜜糠用量对白芍炮制工艺的影响,筛选出最佳工艺参数。结果酒润蜜糠炒白芍最佳炮制工艺为:黄酒用量15%、炒制时间10 min、炒制温度170℃、蜜糠用量40%,验证结果与预测结果吻合。结论优选的白芍炮制工艺稳定可行,可为白芍炮制及相关研究提供参考依据。 展开更多
关键词 酒润蜜糠炒白芍 工艺优化 层次分析法 熵权法 box-behnken响应面法 芍药苷 芍药内酯苷 羟基芍药苷
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基于层次分析法结合Box-Behnken设计响应面法优选滋阴止眩方的提取工艺研究
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作者 王璟 赵学龙 +5 位作者 代瑞雪 单鸣秋 赵峰 虞鹤鸣 包贝华 张丽 《时珍国医国药》 北大核心 2026年第1期84-91,共8页
目的依据传统煎煮法优选滋阴止眩方的最佳提取工艺。方法采用HPLC法和紫外-可见分光光度法,以出膏率、天麻素和总糖含量为指标,利用层次分析法确定各指标的权重系数,确定综合评分方法,以提取时间、加水倍数和提取次数为考察因素,在单因... 目的依据传统煎煮法优选滋阴止眩方的最佳提取工艺。方法采用HPLC法和紫外-可见分光光度法,以出膏率、天麻素和总糖含量为指标,利用层次分析法确定各指标的权重系数,确定综合评分方法,以提取时间、加水倍数和提取次数为考察因素,在单因素考察基础上结合Box-Behnken设计-响应面法优选滋阴止眩方最佳提取工艺参数。结果根据层次分析确定出膏率、天麻素、总糖的权重系数分别为0.5390、0.2972、0.1638,滋阴止眩方的最佳提取工艺为加18倍量水,提取1.5 h,提取3次,验证结果与模型预测值之间的RSD为0.23%,说明本模型具有良好的预测性。结论采用响应面法优选的滋阴止眩方提取工艺方法可行,为滋阴止眩合剂后续的工艺开发和的质量控制提供参考。 展开更多
关键词 滋阴止眩方 box-behnken响应面法 层次分析法 提取工艺 天麻素
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Box-Behnken设计-效应面法优化黄芩汤自组装纳米粒与特比萘芬共载药纳米粒的处方工艺研究
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作者 何沂灿 陈家乐 +2 位作者 邬子妍 袁海龙 沈成英 《中草药》 北大核心 2026年第2期474-484,共11页
目的 优化黄芩汤自组装纳米粒(self-assembled nanoparticles of Huangqin Decoction,HQD-SAN)与特比萘芬(terbinafine,TBF)共载药纳米粒(TBF-HQD-SAN NPs)的处方工艺。方法 采用高速离心结合透析法拆分得到HQD-SAN,进一步包载TBF制备为... 目的 优化黄芩汤自组装纳米粒(self-assembled nanoparticles of Huangqin Decoction,HQD-SAN)与特比萘芬(terbinafine,TBF)共载药纳米粒(TBF-HQD-SAN NPs)的处方工艺。方法 采用高速离心结合透析法拆分得到HQD-SAN,进一步包载TBF制备为TBF-HQD-SAN NPs。在单因素考察的基础上,以HQD-SAN质量浓度、磁力搅拌速度和搅拌时间为考察因素,以TBF载药量、黄芩苷包封率及载药量为考察指标,采用3因素3水平Box-Behnken设计(Box-Behnken design,BBD)-效应面法(response surface methodology,RSM)优化TBF-HQD-SAN NPs的处方和工艺。对最优处方和工艺制备的TBF-HQD-SAN NPs进行形貌、粒径分布、ζ电位及载药能力、溶解度进行表征,并考察其对红色毛癣菌Trichophyton rubrum、须癣毛癣菌T. mentagrophytes、犬小孢子菌Microsporum canis的抗菌活性。结果 工艺优化分析表明,所建2次回归模型拟合度优异(R2均>0.99),HQD-SAN质量浓度、搅拌速度、搅拌时间及部分交互项对指标影响显著(P<0.05)。效应面分析显示,TBF载药量随HQD-SAN质量浓度升高而降低,随磁力搅拌速度、磁力搅拌时间先增后降;黄芩苷包封率、载药量随HQD-SAN质量浓度升高而增加,随磁力搅拌速度、磁力搅拌时间延长而降低。模型优选最优工艺为HQD-SAN质量浓度5.6mg/mL,TBF 5 mg,蒸馏水4 mL,超声(50 W、40 kHz)30 min,760 r/min磁力搅拌1.5 h,0.8μm滤膜滤过,即得;验证实验中各指标实测值与预测值接近(RSD<5%)。所得TBF-HQD-SAN NPs的粒径为(185.10±1.73)nm,多分散指数(polydispersity index,PDI)为0.22±0.01,ζ电位为(-15.17±1.40)m V;TBF包封率为(99.81±0.33)%,载药量为(3.32±0.09)%;黄芩苷包封率为(58.59±1.42)%、载药量为(6.71±0.15)%;TBF、TBF-HQD-SAN物理混合物(physical mixture,PM)、TBF-HQD-SAN NPs的平衡溶解度分别为(2.27±0.09)、(15.70±1.66)、(78.20±2.22)μg/mL。抗菌实验结果显示,TBF-HQD-SAN NPs的抗菌活性(MIC值为0.15~0.31μg/mL,以TBF计为4.98~10.13 ng/mL)显著优于HQD-SAN(MIC值为1.56~3.13 mg/mL)、TBF(MIC值为0.06~0.50μg/mL)(P<0.05)。结论 BBD成功优化了TBF-HQD-SAN NPs处方和工艺,该制剂粒径均一、载药性能优异,且抗菌效果显著提升,为其后续研究奠定了基础。 展开更多
关键词 黄芩汤 自组装纳米粒 特比萘芬 共载药纳米粒 黄芩苷 box-behnken设计-效应面法 抗皮肤癣菌
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基于单因素结合Box-Behnken法的钨酸铵蒸发结晶提纯
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作者 肖来荣 李绍豪 +6 位作者 赵小军 王馨悦 王子豪 蔡圳阳 陆乐康 刘赛男 李庆奎 《稀有金属材料与工程》 北大核心 2026年第3期722-729,共8页
采用单因素+Box-Behnken响应曲面法对钨酸铵溶液蒸发结晶法除杂工艺进行优化,以制备更高纯度的仲钨酸铵(APT)。首先,以降低APT中4种杂质(Na、K、S、Mo元素)总含量为出发点,利用单因素法初步确定结晶温度、搅拌线速度、钨酸铵溶液初始浓... 采用单因素+Box-Behnken响应曲面法对钨酸铵溶液蒸发结晶法除杂工艺进行优化,以制备更高纯度的仲钨酸铵(APT)。首先,以降低APT中4种杂质(Na、K、S、Mo元素)总含量为出发点,利用单因素法初步确定结晶温度、搅拌线速度、钨酸铵溶液初始浓度的优选范围。其次,通过Box-Behnken响应曲面法对APT的蒸发结晶除杂工艺进一步优化,研究3种因素对APT中4种杂质总量的相互影响规律。结果表明,3种因素对4种杂质总量的影响顺序为:钨酸铵溶液初始浓度>蒸发温度>搅拌线速度;较佳工艺条件为蒸发温度94℃,搅拌线速度1.25 m/s,钨酸铵溶液初始浓度73 g/L。该实验条件下,制备所得APT 4种杂质总含量降低至39.351 mg/L,与响应曲面法模型的最优预测值的相对误差仅为4.110%,APT纯度达到4N;生成的APT晶体为伴生有少量碎晶的柱状长方体形貌,层状结构明显,粒径分布均匀,晶粒细化明显。 展开更多
关键词 蒸发结晶 APT 钨酸铵溶液 响应曲面法 杂质含量
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AHP-熵权法结合Box-Behnken响应面法优化蒲公英多成分提取工艺
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作者 廖香莲 吴新 +5 位作者 陈志元 张帆 吴涛 杨烨辉 杨强 胡力飞 《药物评价研究》 北大核心 2026年第1期191-201,共11页
目的 建立蒲公英超高效液相色谱(UPLC)多成分定量分析方法,优化其多成分提取工艺,为蒲公英质量控制提供参考。方法 采用Shim-pack Scepter C_(18)-120(100 mm×2.1 mm,1.9μm)色谱柱,流动相为乙腈(A)-0.1%磷酸水溶液(B)梯度洗脱,体... 目的 建立蒲公英超高效液相色谱(UPLC)多成分定量分析方法,优化其多成分提取工艺,为蒲公英质量控制提供参考。方法 采用Shim-pack Scepter C_(18)-120(100 mm×2.1 mm,1.9μm)色谱柱,流动相为乙腈(A)-0.1%磷酸水溶液(B)梯度洗脱,体积流量0.3 mL·min^(-1),检测波长327 nm(0~35 min)、210 nm(35~50 min),进样量1μL,柱温30℃,建立蒲公英6个酚类成分(单咖啡酰酒石酸、绿原酸、咖啡酸、菊苣酸、异绿原酸A、木犀草素)和3个三萜类成分(羽扇豆醇、蒲公英甾醇、蒲公英萜醇)的同步定量分析方法;以乙醇体积分数、溶剂倍数、提取时间、提取次数为考察因素,各成分质量分数的综合评分为评价指标,结合化学计量学分析确定层次分析法(AHP)的判断矩阵,通过AHP-熵权法计算各成分质量分数的综合权重系数,最终运用Box-Behnken设计-响应面法(BBD-RSM)优选蒲公英多成分提取工艺。结果 建立的UPLC分析方法可实现9种目标成分的快速、准确同步定量;最优提取工艺下,单咖啡酰酒石酸、绿原酸、咖啡酸、菊苣酸、异绿原酸A、木犀草素、羽扇豆醇、蒲公英甾醇、蒲公英萜醇的平均质量分数分别为3.51、0.60、0.56、6.37、0.26、0.20、0.42、0.62、0.56 mg·g^(-1);乙醇体积分数对2类成分质量分数的影响与成分的极性有关,其中对高极性酚类成分质量分数影响更为显著,对低极性三萜类成分影响呈现不同规律;AHP-熵权法计算得出的样本提取综合评分受各考察因素的协同作用影响,BBD-RSM建立的模型显著,最优提取条件为20倍70%乙醇提取3次,每次100 min。结论 建立的蒲公英UPLC多成分定量分析方法稳定,AHP-熵权法结合Box-Behnken设计-响应面法的研究策略可有效实现蒲公英多成分提取工艺的综合评价与高效提取,为蒲公英的质量研究及应用提供参考。 展开更多
关键词 碱地蒲公英 超高效液相色谱(UPLC) 层次分析法 熵权法 box-behnken设计-响应面法 单咖啡酰酒石酸 绿原酸 咖啡酸 菊苣酸 异绿原酸A 木犀草素 羽扇豆醇 蒲公英甾醇 蒲公英萜醇
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层次分析-熵权复合权重法结合Box-Behnken响应面优化疏筋解毒方的提取工艺
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作者 邓庆庆 王小平 王亚丽 《华西药学杂志》 北大核心 2026年第1期55-61,共7页
目的优化疏筋解毒方的提取工艺。方法以CaCO_(3)含量为指标确定矿物药先煎时间;以天麻素、芍药苷、落新妇苷含量及出膏率的综合评分(采用层次分析法-熵权法复合权重法计算)为评价指标,通过单因素试验筛选煎煮次数、时间、加水量及浸泡... 目的优化疏筋解毒方的提取工艺。方法以CaCO_(3)含量为指标确定矿物药先煎时间;以天麻素、芍药苷、落新妇苷含量及出膏率的综合评分(采用层次分析法-熵权法复合权重法计算)为评价指标,通过单因素试验筛选煎煮次数、时间、加水量及浸泡时间参数,结合Box-Behnken响应面法优化工艺。结果最佳提取工艺为:生龙骨等矿物药先煎30 min,随后加入天麻、白芍、土茯苓、地黄等药材,用14、12倍水煎煮2次,每次100 min,并于第2次煎煮结束前15 min加入钩藤。结论优化的提取工艺稳定可行,可为疏筋解毒方的制剂成型及后续开发提供参考。 展开更多
关键词 疏筋解毒方 box-behnken响应面法 层次分析法 熵权法 提取工艺 天麻素 高效液相色谱法 白芍苷
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Box-Behnken响应面法优选贯叶金丝桃中总酚和总黄酮提取工艺
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作者 周坤 马良 +2 位作者 刘春芳 郭岳瀚 陈慧 《中国药业》 2026年第3期54-59,共6页
目的优选贯叶金丝桃中总酚和总黄酮的提取工艺。方法分别采用亚硝酸钠-硝酸铝-氢氧化钠[NaNO2-Al(NO3)3-NaOH]法和福林酚(Folin-Ciocalte)试剂法显色,采用紫外-分光光度法分别于760 nm和510 nm波长处测定总酚、总黄酮的含量。以液料比... 目的优选贯叶金丝桃中总酚和总黄酮的提取工艺。方法分别采用亚硝酸钠-硝酸铝-氢氧化钠[NaNO2-Al(NO3)3-NaOH]法和福林酚(Folin-Ciocalte)试剂法显色,采用紫外-分光光度法分别于760 nm和510 nm波长处测定总酚、总黄酮的含量。以液料比、提取温度、乙醇体积分数、提取时间为考察因素,以总酚、总黄酮提取率的综合评分为评价指标,采用Box-Behnken响应面法优选最佳提取工艺,并进行验证试验。结果最佳提取工艺为液料比23倍,提取温度46℃,乙醇体积分数60%,提取时间50 min,提取2次。此工艺条件下,总酚、总黄酮提取率分别为10.08%和8.28%,RSD分别为1.27%和1.42%(n=3),综合评分为98.62。结论该提取工艺稳定、可行,可用于贯叶金丝桃中总酚和总黄酮的提取。 展开更多
关键词 box-behnken响应面法 贯叶金丝桃 总酚 总黄酮 提取工艺
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层次分析-熵权法结合Box-Behnken响应面法优选清肺化痰汤提取工艺
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作者 刘信秋 胡传春 +3 位作者 李艳玲 周萌萌 王纪伟 左亚锋 《中国药业》 2026年第3期40-44,共5页
目的优选清肺化痰汤的提取工艺。方法以加水量、煎煮时间、煎煮次数为考察因素,以提取液中总黄酮含量、总三萜含量及干膏得率的综合评分为评价指标,采用层次分析-熵权法确定各指标权重系数,采用单因素试验结合Box-Behnken响应面法优选... 目的优选清肺化痰汤的提取工艺。方法以加水量、煎煮时间、煎煮次数为考察因素,以提取液中总黄酮含量、总三萜含量及干膏得率的综合评分为评价指标,采用层次分析-熵权法确定各指标权重系数,采用单因素试验结合Box-Behnken响应面法优选提取工艺,并进行验证。结果干膏得率、总黄酮含量、总三萜含量的权重系数分别为0.07,0.60,0.33。最佳提取工艺为加10倍量水,煎煮2次,每次75 min。此工艺条件下,提取液中总黄酮和总三萜的含量分别为0.32%和0.41%(n=3),干膏得率为36.91%,综合评分为99.06。结论优选工艺稳定、可行,重复性和可操作性好,可为后期清肺化痰汤的开发和临床应用提供参考。 展开更多
关键词 清肺化痰汤 层次分析-熵权法 box-behnken响应面法 提取工艺
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Study on the effect of preparation method on denitration performance of Co-modified Ce/TiO_(2) catalyst
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作者 YU Chao ZHANG Boya +2 位作者 SHEN Kai HAN Yuxuan ZHANG Yaping 《燃料化学学报(中英文)》 北大核心 2026年第3期79-91,共13页
This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s... This study systematically conducted preparation optimization and performance investigations on Co-modified Ce/TiO_(2) catalysts,with a focus on examining how preparation methods and Co loading regulate the catalyst’s low-temperature denitrification activity.After identifying optimal preparation parameters via condition screening,multiple characterization techniques-including BET,XRD,XPS,H_(2)-TPR and in situ DRIFTS-were employed to deeply analyze the catalyst’s physicochemical properties and reaction mechanism.Results demonstrated that compared to the impregnation and co-precipitation methods,the Ce-Co_(0.025)/TiO_(2)-SG catalyst(prepared by the sol-gel method with a Co/Ti mass ratio of 0.025)exhibited significantly superior denitrification activity:NO conversion remained stably above 95%in the 225−350℃ temperature range,and it displayed high N_(2) selectivity.Characterization analysis revealed that abundant surface oxygen vacancies,a high proportion of Ce^(3+) species,and prominent acidic sites collectively contributed to enhancing its low-temperature denitrification performance.This work provides reference value for the development of highly efficient low-temperature denitrification catalysts. 展开更多
关键词 preparation method Co Ce/TiO_(2) low-temperature denitration NH3-SCR
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A New Inversion-free Iterative Method for Solving the Nonlinear Matrix Equation and Its Application in Optimal Control
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作者 GAO Xiangyu XIE Weiwei ZHANG Lina 《应用数学》 北大核心 2026年第1期143-150,共8页
In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to ... In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method. 展开更多
关键词 Nonlinear matrix equation Maximal positive definite solution Inversion-free iterative method Optimal control
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Broadband ground motion simulation and analysis of a near-fault 3D basin-mountain coupling site based on the hybrid method
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作者 Liu Zhongxian Tang Kang +2 位作者 Li Chengcheng Yuan Xiaoming Zhang Hai 《Earthquake Engineering and Engineering Vibration》 2026年第1期87-110,共24页
This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SE... This study presents an effective hybrid simulation approach for simulating broadband ground motion in complex near-fault locations.The approach utilizes a deterministic approach based on the spectral element method(SEM),which is used to simulate low-frequency ground motion(f<1 Hz)by incorporating an innovative efficient discontinuous Galerkin(DG)method for grid division to accurately model basin sedimentary layers at reduced costs.It also introduces a comprehensive hybrid source model for high-frequency random scattering and a nonlinear analysis module for basin sedimentary layers.Deterministic outcomes are combined with modified three-dimensional stochastic finite fault method(3D-EXSIM)simulations of high-frequency ground motion(f>1 Hz).A fourth-order Butterworth filter with zero phase shift is employed for time-domain filtering of low-and high-frequency time series at a crossover frequency of 1 Hz,merging the low and high-frequency ground motions into a broadband time series.Taking an Ms 6.8 Luding earthquake,as an example,this hybrid method was used for a rapid and efficient simulation analysis of broadband ground motion in the region.The accuracy and efficiency of this hybrid method were verified through comparisons with actually observed station data and empirical attenuation curves.Deterministic method simulation results revealed the effects of mountainous topography,basin effects,nonlinear effects within the basin’s sedimentary layers,and a coupling interaction between the basin and the mountains.The findings are consistent with similar studies,showing that near-fault sedimentary basins significantly focus and amplify strong ground motion,and the soil’s nonlinear behavior in the basin influences ground motion to varying extents at different distances from the fault.The mountainous topography impacts the basin’s response to ground motion,leading to barrier effects.This research provides a scientific foundation for seismic zoning,urban planning,and seismic design in nearfault mountain basin regions. 展开更多
关键词 hybrid ground motion simulation method spectral element method three-dimensional stochastic finite fault method near-fault basin-mountain coupling effect basin effect nonlinear effect
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基于Box-Behnken响应面法结合正交试验的达原饮提取工艺优化
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作者 刘菊 金云隆 +3 位作者 孔祥才 高晓洁 张红伟 白明学 《中国现代中药》 2026年第1期158-165,共8页
目的:优化达原饮的提取工艺和灭菌工艺。方法:以加水量、提取时间、提取次数为考察因素,以达原饮中10个有效成分的总含量、浸膏得率为评价指标,通过Box-Behnken响应面法建立模型,优选达原饮的最佳提取工艺并进行验证实验。采用正交试验... 目的:优化达原饮的提取工艺和灭菌工艺。方法:以加水量、提取时间、提取次数为考察因素,以达原饮中10个有效成分的总含量、浸膏得率为评价指标,通过Box-Behnken响应面法建立模型,优选达原饮的最佳提取工艺并进行验证实验。采用正交试验,以灭菌温度、灭菌压力、灭菌时间为考察因素,以灭菌后达原饮中微生物测定结果和10个有效成分的总含量为评价指标,优选达原饮的最佳灭菌工艺。结果:达原饮的最佳提取工艺为加水量10倍、提取时间1.5 h,提取2次;最佳灭菌工艺为灭菌温度100℃、灭菌压力60 kPa、灭菌时间45 min。结论:优选的达原饮提取工艺和灭菌工艺简便易行、稳定性好,为达原饮的产业化生产提供参考。 展开更多
关键词 达原饮 box-behnken响应面法 正交试验 浸膏得率 有效含量
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Establishment of a Determination Method for Fruit Texture in Chieh-qua Using Texture Analyzer
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作者 Ying WANG Xuan DU Na LIU 《Agricultural Biotechnology》 2026年第1期54-59,共6页
[Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and pun... [Objectives]This study was conducted to establish a quantitative assessment method for the textural quality of chieh-qua fruit.[Methods]Using two modes of a texture analyzer,namely TPA(texture profile analysis)and puncture,the index data of the fruit were obtained by setting different trigger forces,deformation levels,test speeds,as well as puncture speeds and puncture depths.The data included TPA hardness,adhesiveness,springiness,cohesiveness,gumminess,chewiness,resilience,as well as skin hardness,skin toughness,flesh hardness,fracturability,and compactness.[Results]Different deformation levels had a significant impact on all parameters.Hardness,adhesiveness,gumminess and chewiness showed a trend of first increasing and then decreasing with the deformation level increasing.When the deformation level was 30%,the adhesiveness,gumminess and chewiness reached their maximum values.When the deformation level was 50%,TPA hardness reached its maximum.When the compression speed was 3 mm/s,the measured values of TPA hardness,adhesiveness,chewiness,and resilience were at their maximums.The skin hardness varied significantly under different trigger forces.When the trigger force was 15 g,the skin hardness reached a maximum value of 944.63 g,and the skin toughness,flesh hardness,fracturability,and compactness also reach their maximum values respectively.When the puncture depth was 12 mm,the flesh hardness and skin toughness reached their maximums of 682.51 g and 1.82 mm,respectively.In the TPA mode,the flesh hardness of chieh-qua showed an extremely significant negative correlation with springiness,cohesiveness,and resilience(P<0.01).The fruit fracturability detected by puncture had an extremely significant positive correlation with compactness(P<0.01).[Conclusions]The evaluation method for measuring chieh-qua texture by combining TPA and the puncture mode could accurately and quantitatively reflect the differences in the flesh texture quality of chieh-qua.The optimal parameters for texture measurement of chieh-qua fruit were determined as a 15 g trigger force with 50%deformation and a 3 mm/s compression speed in TPA mode,and a 15 g trigger force with a 12 mm puncture depth in puncture mode.Puncture speed was found to have no significant effect on the texture indices of chieh-qua. 展开更多
关键词 CHIEH-QUA Texture analyzer Texture quality Determination method
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A novel scaling method for the elastic ring supporting structure of an aero-engine rotor system: analytical and experimental investigations
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作者 Lei LI Tianyue MA +4 位作者 Zhong LUO Dongwu GAO Xiangdong GE Hui MA Shibin WANG 《Applied Mathematics and Mechanics(English Edition)》 2026年第1期1-18,共18页
The testing of large structures is limited by high costs and long cycles, making scaling methods an attractive solution. However, the scaling process of elastic rings introduces complexities in multi-parameter geometr... The testing of large structures is limited by high costs and long cycles, making scaling methods an attractive solution. However, the scaling process of elastic rings introduces complexities in multi-parameter geometric distortions, leading to a diminution in the predictive accuracy of the distorted similitude. To address this challenge, this study formulates a novel set of scaling laws, tailored to account for the intricate geometric distortions associated with elastic rings. The proposed scaling laws are formulated based on the intrinsic deformation characteristics of elastic rings, rather than the traditional systemic governing equations. Numerical and experimental cases are conducted to assess the efficacy and precision of the proposed scaling laws, and the obtained results are compared with those achieved by traditional methods. The outcomes demonstrate that the scaling laws put forth by this study significantly enhance the predictive capabilities for deformations of elastic rings. 展开更多
关键词 rotor system AERO-ENGINE elastic ring scaling method supporting structure
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Multiphysics Implicit Coupling Method for Fluid,Particles,and Large-Deformation Structures
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作者 Xiangxiang Wang Hualong Xie +3 位作者 Yue Yu Min Li Yubin Wang Fei Xing 《Computer Modeling in Engineering & Sciences》 2026年第2期367-401,共35页
This study presents an implicit multiphysics coupling method integrating Computational Fluid Dynamics(CFD),the Multiphase Particle-in-Cell(MPPIC)model,and the Finite Element Method(FEM),implemented with OpenFOAM,Calcu... This study presents an implicit multiphysics coupling method integrating Computational Fluid Dynamics(CFD),the Multiphase Particle-in-Cell(MPPIC)model,and the Finite Element Method(FEM),implemented with OpenFOAM,CalculiX,and preCICE to simulate fluid-particle-structure interactions with large deformations.Mesh motion in the fluid field is handled using the radial basis function(RBF)method.The particle phase is modeled by MPPIC,where fluid-particle interaction is described through momentum exchange,and inter-particle collisions are characterized by collision stress.The structural field is solved by nonlinear FEM to capture large deformations induced by geometric nonlinearity.Coupling among fields is realized through a partitioned,parallel,and non-intrusive iterative strategy,ensuring stable transfer and convergence of interface forces and displacements.Notably,the influence of particles on the structure is not direct but mediated by the fluid,while structural motion directly affects particle dynamics.The results demonstrate that the proposed approach effectively captures multiphysics interaction processes and provides a valuable reference for numerical modeling of coupled fluid-particle-structure systems. 展开更多
关键词 Fluid-particle-structure interaction large deformation partitioned method non-intrusive coupling
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A Cost-Effective Approach to Precisely Estimate Singlet-Triplet Energy Gaps in MR-TADF Molecules:Combining Delta Self-Consistent Field and Time-Dependent Density Functional Theory Methods
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作者 Qian Jina Dong Wang 《Chinese Journal of Chemical Physics》 2026年第1期41-50,I0021-I0032,I0042,共23页
As a novel class of purely organic fluores-cent materials,multiple resonance thermal-ly activated delayed fluorescence(MR-TADF)compounds hold significant promise for next-generation display technologies.The efficiency... As a novel class of purely organic fluores-cent materials,multiple resonance thermal-ly activated delayed fluorescence(MR-TADF)compounds hold significant promise for next-generation display technologies.The efficiency of exciton utilization and the overall performance of organic light-emit-ting devices are closely linked to the singlet-triplet energy gap(ΔE_(ST))of MR-TADF emitters.Identifying an economic and accu-rate theoretical approach to predictΔE_(ST)would be beneficial for high-throughput screening and facilitate the inverse design of MR-TADF molecules.In this study,we evaluated the S_(1)state energy(E(S_(1))),T_(1)state ener-gy(E(T_(1))),andΔE_(ST)using three different physical interpretations:adiabatic excitation ener-gy,vertical absorption energy,and vertical emission energy.We employed the time-depen-dent density functional theory(TDDFT)and delta self-consistent field(ΔSCF)methods to calculate E(S_(1)),E(T_(1)),andΔE_(ST)for 20 MR-TADF molecules reported in the literature.We compared these calculated values with experimental data obtained from fluorescence spec-troscopy at room-temperature(or 77 K)and phosphorescence spectroscopy conducted at 77 K.Our findings indicate that the vertical absorption energy at the S0 state minimum,deter-mined by theΔSCF method,accurately predicts the S_(1)state energy.Similarly,the vertical absorption energy at the S0 state minimum,calculated using the TDDFT method,effectively predicts the T_(1)state energy.TheΔE_(ST)derived from the difference between these two excita-tion energies exhibited the smallest mean absolute error of only 0.039 eV compared to the ex-perimental values.This combination represents the most accurate and cost-effective method reported to date for predicting theΔE_(ST)of MR-TADF molecules,and can be integrated into AI-driven inverse design workflows for new emitters. 展开更多
关键词 Organic light-emitting diode Multiple resonance thermally activated delayed fluorescence emitter Single-triplet energy gap Delta self-consistent field method Time-de-pendent density functional theory method
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Investigation of equivalent strength parameters of soil-rock mixture using numerical manifold method
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作者 Junfeng Li Yongtao Yang +2 位作者 Yang Xia Hong Zheng Shuilin Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期637-650,共14页
As binary geological media,soil-rock mixtures(SRMs)exhibit a distinct gradational composition,leading to their unique mechanical behaviors.To appraise the stability of SRM slopes,it is essential to determine equivalen... As binary geological media,soil-rock mixtures(SRMs)exhibit a distinct gradational composition,leading to their unique mechanical behaviors.To appraise the stability of SRM slopes,it is essential to determine equivalent parameters of SRMs,which are typically obtained through experimental and numerical methods.In contrasted to other numerical methods,the numerical manifold method(NMM)is more effective in addressing SRM problems.This is because the high-precision regular mathematical meshes in NMM can be used without aligning with the soil-rock interfaces and boundaries of SRMs.In the current research,the equivalent strength parameters of SRMs,i.e.the equivalent cohesion ce and internal friction angleϕ_(e),are determined using NMM.Initially,an NMM triaxial numerical model is established and validated based on triaxial experiments.Subsequently,the soil and rock parameters are derived through parameter inversion.Moreover,the impacts of rock content,size,shape and rock blocks'major-axis orientation on ce andϕ_(e) of SRMs are thoroughly examined using the NMM triaxial numerical model.Additionally,a fitting function is proposed to linkϕ_(e) to the rock content and size of SRMs.When other influencing factors are fixed,the above fitting model leads to the following conclusions:(1)the predictedϕ_(e) of SRMs increase with the increase of rock content;and(2)SRM samples with smaller rocks display a higher predictedϕ_(e). 展开更多
关键词 Soil-rock mixtures Equivalent strength parameters Numerical manifold method
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Subtitle Translation Methods of The Good Wife From Functional Equivalence Perspective
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作者 WANG Ya-kun BAO De-wang 《Journal of Literature and Art Studies》 2026年第1期26-30,共5页
The Good Wife is an American TV series that focuses on women’s independence,politics,and law.The drama has been remade in China,Japan,and South Korea.This research aims to use Nida’s Functional Equivalence Theory to... The Good Wife is an American TV series that focuses on women’s independence,politics,and law.The drama has been remade in China,Japan,and South Korea.This research aims to use Nida’s Functional Equivalence Theory to analyze the methods of its English-to-Chinese subtitle translation by considering social,cultural,and historic backgrounds between China and America.After data collection and case analysis,the study found that:(1)Five major translation methods are adopted in the subtitle translation of The Good Wife.They are free translation,variation,literal translation,addition,and omission.Among them,free translation is the most frequently used,while omission is used least.(2)The subtitle translation of films and TV series is limited by time and space restrictions,social-cultural differences,and other factors.When translating,translators should try to use humorous words,euphemism,intonation,and other ways,and combine different methods such as literal translation,free translation,variation,addition,omission,and other methods to seek equivalence both in the meaning and function of subtitles under the guidance of Functional Equivalence Theory. 展开更多
关键词 subtitle translation Functional Equivalence Theory The Good Wife translation methods
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Pile installation effects in natural soft clays:A semi-analytical solution using strain path method
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作者 Liang Li Pan Zhou +3 位作者 Jingpei Li Seyedmohsen Miraei Peng Feng Mingdong Wei 《Journal of Rock Mechanics and Geotechnical Engineering》 2026年第1期728-744,共17页
This paper develops a semi-analytical solution for pile penetration in natural soft clays using the strain path method(SPM).The stress-strain behavior of soils is characterized by the S-CLAY1S model,which can capture ... This paper develops a semi-analytical solution for pile penetration in natural soft clays using the strain path method(SPM).The stress-strain behavior of soils is characterized by the S-CLAY1S model,which can capture the anisotropic evolution and destructuring nature of soft clays.By integrating the S-CLAY1S model into the theoretical framework of the SPM,a set of ordinary differential equations is formulated with respect to the vertical coordinate of soil particles.The distribution of excess pore water pressure(EPWP)following pile installation is approximated through one-dimensional(1D)radial integration around the pile shaft.The distribution of stresses and EPWP,along with the evolution of fabric anisotropy within the soil surrounding the pile,is presented to illustrate the response of pile penetration in natural soft clays.The proposed solution is validated against existing theoretical solutions using the SPM and cavity expansion method(CEM),along with experimental data.The findings demonstrate that the SPM reveals lower radial effective stresses and EPWP at the pile shaft than that of CEM.Pile penetration alters the soil's anisotropic properties,inducing rotational hardening and affecting post-installation stress distribution.Soil destructuration eliminates bonding among particles near the pile,resulting in a complete disruption of soil structure at the pile surface,which is particularly pronounced for higher initial soil structure ratios.Minimal variation was observed in the three principal stresses and shear stress on the cone side surface as the angle increased from 18°to 60°,except for a slight reduction in EPWP. 展开更多
关键词 Pile penetration Strain path method Natural soft clays Anisotropy evolution Destructuration
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