Hepatitis C virus(HCV)and hepatitis B virus(HBV)infections are increasingly recognized as significant etiological factors in the pathogenesis of B-cell non-Hodgkin’s lymphomas(B-NHLs).Epidemiological and molecular st...Hepatitis C virus(HCV)and hepatitis B virus(HBV)infections are increasingly recognized as significant etiological factors in the pathogenesis of B-cell non-Hodgkin’s lymphomas(B-NHLs).Epidemiological and molecular studies have demonstrated a consistent association between chronic viral infection and B-NHLs.Multiple pathogenic mechanisms have been implicated in lymphomagenesis,both direct and indirect,including chronic antigenic stimulation,direct infection of B cells,and viral protein-mediated oncogenic signaling,It is likely that a combination of several pathogenic conditions is required to eventually lead to the development of lymphoma.The prevalence of B-cell lymphomas among individuals with chronic HCV or HBV infection presents a complex pathogenetic scenario,given the tumor heterogeneity and variable clinical behavior,and poses therapeutic challenges,due to the partial efficacy of current treatment options.The advent of direct-acting antivirals(DAAs)for HCV and high-genetic barrier nucleos(t)ide analogues(NAs)for HBV has improved patient outcomes.In indolent HCV-associated B-NHLs,antiviral therapy with DAAs alone often achieves sustained virologic response and may lead to lymphoma regression.Conversely,aggressive subtypes like diffuse large B-cell lymphomas require combination treatment with immunochemotherapy.In the setting of HBV-associated lymphomas,antiviral prophylaxis with potent NAs(e.g.,entecavir or tenofovir)is essential to prevent HBV reactivation during rituximab-containing chemotherapy regimen.The integration of antiviral and anticancer therapies has been shown to enhance survival outcomes while mitigating hepatic toxicity.A comprehensive understanding of the biological interplay between chronic viral infection and B-cell transformation is critical for optimizing diagnostic and therapeutic strategies.Aim of this viewpoint is to provide evidence that early viral detection and prompt management remain the most effective strategies to improve survival rates and to reduce treatment-related morbidity in these patients.展开更多
Objective:To study the effect of transcranial magnetic stimulation(TMS)on improving motor symptoms in patients with Parkinson’s disease(PD).Methods:60 PD patients who visited the hospital from September 2023 to Augus...Objective:To study the effect of transcranial magnetic stimulation(TMS)on improving motor symptoms in patients with Parkinson’s disease(PD).Methods:60 PD patients who visited the hospital from September 2023 to August 2024 were selected as samples and randomly divided into two groups.Group A received conventional medication plus TMS treatment,while Group B received medication only.The efficacy of motor function improvement,neurological symptoms,mental state,sleep quality,quality of life,and adverse reactions was compared between the two groups.Results:The efficacy of Group A was higher than that of Group B(P<0.05).The scores of the Scales for Outcomes in Parkinson’s Disease-Autonomic(SCOPA-AUT),Mini-Mental State Examination(MMSE),and Pittsburgh Sleep Quality Index(PSQI)in Group A were lower than those in Group B(P<0.05).The quality of life scale(SF-36)score in Group A was higher than that in Group B(P<0.05).The adverse reaction rate in Group A was lower than that in Group B(P<0.05).Conclusion:TMS used in the treatment of PD patients can improve patients’mental state and motor function,optimize sleep quality and quality of life,and is safe and efficient.展开更多
Based on field survey located by GPS, it is obtained landslides' location and distribution information by the method of remote sensing in this paper. The vector data of environmental factors that breed and induce lan...Based on field survey located by GPS, it is obtained landslides' location and distribution information by the method of remote sensing in this paper. The vector data of environmental factors that breed and induce landslides such as the elevation, the slope, the vegetation cover, the lithology, the rainfall and so on are gained using GIS(geographical information system) techniques of spatial analysis. All the data obtained are managed through building landslide management system. At the same time, the system is made the platform to appraise the relationship between the distribution of landslides and the environmental factors. The results indicate: landslides take place relatively easily in the slope range between 10° and 25°; most landslides are in the mixed area of bush and grass with a coverage degree of from 20° to 65°; the distribution of landslides has a positive relationship with the distribution of annual rainfall. The risk degree of Panxi Area is zoned and mapped by the model of liner stack using GIS technique, and the result indicates: the place of high risk degree is the belt of Panzhihua-Miyi-Dechang-Mugu and southeast of Huili county and Huidong county,and area is about 512 707 hm^2.展开更多
According to the objective reality in Yunnan Province,such as great difference of weather,a great proportion of minorities,technological backwardness of agricultural production,low conversion rate of research accompli...According to the objective reality in Yunnan Province,such as great difference of weather,a great proportion of minorities,technological backwardness of agricultural production,low conversion rate of research accomplishments,and a limited number of agricultural technical personnel,ASP.NET technique and SQL Server 2005 database technique are adopted.Database platform of county agricultural production technology in Yunnan Province is established by using B/S structure.This platform includes presentation layer,application layer,and data layer,involving regional information,technology column information,technology classification information,technology content and other databases.It has six functional modules,namely information browse,system management,regional maintenance,technical section maintenance,category maintenance and technical information release,integrating crop cultivation,livestock breeding,economic forest management,plant protection,agricultural products processing,agricultural machinery use and other agricultural technical information.This platform can exchange information dynamically with the client,perform the query request from users,and send the result to users.This database platform has friendly interface,profuse information,high pertinency and so on,which offers rich and reliable information resources to farmers,agricultural technical personnel,and government.At present,this platform has been popularized in some areas of Yunnan Province and has obtained good results.展开更多
A fully automated approach for detecting land use/cover change using remote sensing data,GIS data,GPS data is presented.The integrating raster with vector methods of updating the basic land use/land cover map based on...A fully automated approach for detecting land use/cover change using remote sensing data,GIS data,GPS data is presented.The integrating raster with vector methods of updating the basic land use/land cover map based on 3S technology is becoming one of the most important developing directions in 3S application fields,land-use and cover change fields over the world.It has been successful applied in two tasks of the Ministry of Land and Resources of China,and takes some benefit.展开更多
The intensive care unit(ICU)is a complex setting by nature,and some have described it as bizarre due to its numerous sirens that sound when anything is dangerous,constant activity,equipment,bright lights,and high fata...The intensive care unit(ICU)is a complex setting by nature,and some have described it as bizarre due to its numerous sirens that sound when anything is dangerous,constant activity,equipment,bright lights,and high fatality rate.The demands placed on nurses to care for critically ill patients in this environment frequently prevent nurses and other health‑care professionals from acknowledging the feelings of patient’s relatives or family caregivers,resulting in a hostile environment from the patient’s relative’s perspective.When a patient’s family enters the ICU,they feel that hospital administrators do little to nothing to alleviate their discomfort and fear.Despite research demonstrating the importance of providing a homely environment for patients’families,In Nigeria ICU is still far behind how a conventional ICU environment should be structured to accommodate patient’s relations in the unit.The goal of this study was to look at the patient’s relative’s perspective on providing care for a critically ill patient in an ICU,with a focus on the unit’s complexity and overall experience.Based on the findings of this study,we recommend that hospital administrators ensure that the environment of the upcoming ICU is designed to meet the needs of patient’s relatives by addressing identified environmental concerns,like caring neglect,by providing a friendly and stress‑free environment.展开更多
The causes and the problems of integration of scientific & technical innovation (ISTI) and inevitability are proposed. The status of domestic scientific & technical innovation is analysed. A series of emergent man...The causes and the problems of integration of scientific & technical innovation (ISTI) and inevitability are proposed. The status of domestic scientific & technical innovation is analysed. A series of emergent managerial problems caused by the system ISTI (SISTI) are pointed out. Because of Hall three dimensions structure's enlightenment, a three dimensional logical net diagram in which the system integration of innovation based on problem in real world but not on disciplinary logic is drawn. The intelligent group' s need span is greater under the conditions of relatively low material level than common groups who have lower degree of education. The SISTI is composed by multi-rule and intelligent multi-agent behavior. It is concluded that the logical relationships of integrated technology which based on the author's experience and observation must be considerded for a valid management of SISTI.展开更多
Remote sensing,geographic information system and GPS(3S)technology have been well recognized as comprehensive,accurate and up-to-date information collection methods,which are increasingly adopted in biodiversity conse...Remote sensing,geographic information system and GPS(3S)technology have been well recognized as comprehensive,accurate and up-to-date information collection methods,which are increasingly adopted in biodiversity conservation.This review summarizes the application of object-oriented classification methods on biodiversity monitoring projects based on high-resolution remote sensing imagines in China.Biodiversity conservation research based on GIS technology in China is also discussed,with emphasis on the advantages of GIS analysis and modeling function.展开更多
The North-East China is nation commercial grain base of China.It provides important grain supply for other areas of the country every year.The nation and modern farmers are looking for advanced technological solutions...The North-East China is nation commercial grain base of China.It provides important grain supply for other areas of the country every year.The nation and modern farmers are looking for advanced technological solutions to increase production and preserve environment.Considering of this aim,this paper introduce a new planning that using 3S technology to develop precision farming,explaining its technology frame,operation steps and advantages.On the other hand,this paper also introduce the concept of precision farming and discusses the role of 3S technology as a data collection,management and analysis tool.展开更多
This article expounds the economic characteristics of circular agricultural technology.Since the circular agricultural technology has characteristics and externality of public goods,the government participation is nec...This article expounds the economic characteristics of circular agricultural technology.Since the circular agricultural technology has characteristics and externality of public goods,the government participation is necessary in building the technology system of circular agriculture,in order to avoid "free rider" behavior in the consumption of public goods and internalize externality.We analyze the orientation of government's role in building the technology system of circular agriculture:the government is the leader,designer,organizer and regulator in building the technology system of circular agriculture;the government orientates the four roles precisely in building the technology system of circular agriculture,to ensure that they do not cross the line,but be indispensable all the while.展开更多
[Objective] The study aimed at analyzing the dynamic variation of land-use types of the constructed wetland before and after oil-field water irrigation based on 3S technology. [Method] At semi-arid and arid areas in t...[Objective] The study aimed at analyzing the dynamic variation of land-use types of the constructed wetland before and after oil-field water irrigation based on 3S technology. [Method] At semi-arid and arid areas in the west of Jilin Province, water resource balance between the amount of oil-field water supply and ecological water requirement in the constructed wetland irrigated by oil-field water during 2001-2010 was investigated firstly. Afterwards, based on 3S technology, the partition and dynamic variation of land-use types of the constructed wetland before and after oil-field water irrigation in 2001, 2006, 2008 and 2010 were analyzed. [Result] The annual ecological water requirement of the constructed wetland from 2003 to 2010 varied from 1.62×106 to 2.24×106 m3, and the annual amount of oil-field water supply in the region changed from 2.12×106 to 2.84×106 m3, which showed that the supply amount of oil-field water could meet the basic ecological water requirement of the constructed wetland. Meanwhile, compared with 2001, the areas of water region and paddy field in 2010 increased by 2.3 and 10.0 times, and the areas of forest and marsh rose by 40.15% and 29.5.0% respectively. [Conclusion] Water shortage and ecological environment problem of arid and semi-arid areas had been improved by oil-field water irrigation.展开更多
Softswitch technology integrates the su-periorities of both an intelligence net-work and the Internet, which embodiesits maturity and advancement. With ahierarchical network model, it effectivelysolves problems of evo...Softswitch technology integrates the su-periorities of both an intelligence net-work and the Internet, which embodiesits maturity and advancement. With ahierarchical network model, it effectivelysolves problems of evolution and convergenceof current communication networks. It also fol-展开更多
基金supported by the National Italian Research Council(CNR)“Progetto DSB.AD007.305.001”to Monica Rinaldi。
文摘Hepatitis C virus(HCV)and hepatitis B virus(HBV)infections are increasingly recognized as significant etiological factors in the pathogenesis of B-cell non-Hodgkin’s lymphomas(B-NHLs).Epidemiological and molecular studies have demonstrated a consistent association between chronic viral infection and B-NHLs.Multiple pathogenic mechanisms have been implicated in lymphomagenesis,both direct and indirect,including chronic antigenic stimulation,direct infection of B cells,and viral protein-mediated oncogenic signaling,It is likely that a combination of several pathogenic conditions is required to eventually lead to the development of lymphoma.The prevalence of B-cell lymphomas among individuals with chronic HCV or HBV infection presents a complex pathogenetic scenario,given the tumor heterogeneity and variable clinical behavior,and poses therapeutic challenges,due to the partial efficacy of current treatment options.The advent of direct-acting antivirals(DAAs)for HCV and high-genetic barrier nucleos(t)ide analogues(NAs)for HBV has improved patient outcomes.In indolent HCV-associated B-NHLs,antiviral therapy with DAAs alone often achieves sustained virologic response and may lead to lymphoma regression.Conversely,aggressive subtypes like diffuse large B-cell lymphomas require combination treatment with immunochemotherapy.In the setting of HBV-associated lymphomas,antiviral prophylaxis with potent NAs(e.g.,entecavir or tenofovir)is essential to prevent HBV reactivation during rituximab-containing chemotherapy regimen.The integration of antiviral and anticancer therapies has been shown to enhance survival outcomes while mitigating hepatic toxicity.A comprehensive understanding of the biological interplay between chronic viral infection and B-cell transformation is critical for optimizing diagnostic and therapeutic strategies.Aim of this viewpoint is to provide evidence that early viral detection and prompt management remain the most effective strategies to improve survival rates and to reduce treatment-related morbidity in these patients.
文摘Objective:To study the effect of transcranial magnetic stimulation(TMS)on improving motor symptoms in patients with Parkinson’s disease(PD).Methods:60 PD patients who visited the hospital from September 2023 to August 2024 were selected as samples and randomly divided into two groups.Group A received conventional medication plus TMS treatment,while Group B received medication only.The efficacy of motor function improvement,neurological symptoms,mental state,sleep quality,quality of life,and adverse reactions was compared between the two groups.Results:The efficacy of Group A was higher than that of Group B(P<0.05).The scores of the Scales for Outcomes in Parkinson’s Disease-Autonomic(SCOPA-AUT),Mini-Mental State Examination(MMSE),and Pittsburgh Sleep Quality Index(PSQI)in Group A were lower than those in Group B(P<0.05).The quality of life scale(SF-36)score in Group A was higher than that in Group B(P<0.05).The adverse reaction rate in Group A was lower than that in Group B(P<0.05).Conclusion:TMS used in the treatment of PD patients can improve patients’mental state and motor function,optimize sleep quality and quality of life,and is safe and efficient.
文摘Based on field survey located by GPS, it is obtained landslides' location and distribution information by the method of remote sensing in this paper. The vector data of environmental factors that breed and induce landslides such as the elevation, the slope, the vegetation cover, the lithology, the rainfall and so on are gained using GIS(geographical information system) techniques of spatial analysis. All the data obtained are managed through building landslide management system. At the same time, the system is made the platform to appraise the relationship between the distribution of landslides and the environmental factors. The results indicate: landslides take place relatively easily in the slope range between 10° and 25°; most landslides are in the mixed area of bush and grass with a coverage degree of from 20° to 65°; the distribution of landslides has a positive relationship with the distribution of annual rainfall. The risk degree of Panxi Area is zoned and mapped by the model of liner stack using GIS technique, and the result indicates: the place of high risk degree is the belt of Panzhihua-Miyi-Dechang-Mugu and southeast of Huili county and Huidong county,and area is about 512 707 hm^2.
基金Supported by the National Science & Technology Pillar Program during the Eleventh Five-Year Plan Period(2006BAD10A14)
文摘According to the objective reality in Yunnan Province,such as great difference of weather,a great proportion of minorities,technological backwardness of agricultural production,low conversion rate of research accomplishments,and a limited number of agricultural technical personnel,ASP.NET technique and SQL Server 2005 database technique are adopted.Database platform of county agricultural production technology in Yunnan Province is established by using B/S structure.This platform includes presentation layer,application layer,and data layer,involving regional information,technology column information,technology classification information,technology content and other databases.It has six functional modules,namely information browse,system management,regional maintenance,technical section maintenance,category maintenance and technical information release,integrating crop cultivation,livestock breeding,economic forest management,plant protection,agricultural products processing,agricultural machinery use and other agricultural technical information.This platform can exchange information dynamically with the client,perform the query request from users,and send the result to users.This database platform has friendly interface,profuse information,high pertinency and so on,which offers rich and reliable information resources to farmers,agricultural technical personnel,and government.At present,this platform has been popularized in some areas of Yunnan Province and has obtained good results.
文摘A fully automated approach for detecting land use/cover change using remote sensing data,GIS data,GPS data is presented.The integrating raster with vector methods of updating the basic land use/land cover map based on 3S technology is becoming one of the most important developing directions in 3S application fields,land-use and cover change fields over the world.It has been successful applied in two tasks of the Ministry of Land and Resources of China,and takes some benefit.
文摘The intensive care unit(ICU)is a complex setting by nature,and some have described it as bizarre due to its numerous sirens that sound when anything is dangerous,constant activity,equipment,bright lights,and high fatality rate.The demands placed on nurses to care for critically ill patients in this environment frequently prevent nurses and other health‑care professionals from acknowledging the feelings of patient’s relatives or family caregivers,resulting in a hostile environment from the patient’s relative’s perspective.When a patient’s family enters the ICU,they feel that hospital administrators do little to nothing to alleviate their discomfort and fear.Despite research demonstrating the importance of providing a homely environment for patients’families,In Nigeria ICU is still far behind how a conventional ICU environment should be structured to accommodate patient’s relations in the unit.The goal of this study was to look at the patient’s relative’s perspective on providing care for a critically ill patient in an ICU,with a focus on the unit’s complexity and overall experience.Based on the findings of this study,we recommend that hospital administrators ensure that the environment of the upcoming ICU is designed to meet the needs of patient’s relatives by addressing identified environmental concerns,like caring neglect,by providing a friendly and stress‑free environment.
基金Sponsored bythe National Innovation Basein Management on National Defense Science Technology National Economy Mobilization of the SecondPhase of"985"Project
文摘The causes and the problems of integration of scientific & technical innovation (ISTI) and inevitability are proposed. The status of domestic scientific & technical innovation is analysed. A series of emergent managerial problems caused by the system ISTI (SISTI) are pointed out. Because of Hall three dimensions structure's enlightenment, a three dimensional logical net diagram in which the system integration of innovation based on problem in real world but not on disciplinary logic is drawn. The intelligent group' s need span is greater under the conditions of relatively low material level than common groups who have lower degree of education. The SISTI is composed by multi-rule and intelligent multi-agent behavior. It is concluded that the logical relationships of integrated technology which based on the author's experience and observation must be considerded for a valid management of SISTI.
文摘Remote sensing,geographic information system and GPS(3S)technology have been well recognized as comprehensive,accurate and up-to-date information collection methods,which are increasingly adopted in biodiversity conservation.This review summarizes the application of object-oriented classification methods on biodiversity monitoring projects based on high-resolution remote sensing imagines in China.Biodiversity conservation research based on GIS technology in China is also discussed,with emphasis on the advantages of GIS analysis and modeling function.
文摘The North-East China is nation commercial grain base of China.It provides important grain supply for other areas of the country every year.The nation and modern farmers are looking for advanced technological solutions to increase production and preserve environment.Considering of this aim,this paper introduce a new planning that using 3S technology to develop precision farming,explaining its technology frame,operation steps and advantages.On the other hand,this paper also introduce the concept of precision farming and discusses the role of 3S technology as a data collection,management and analysis tool.
文摘This article expounds the economic characteristics of circular agricultural technology.Since the circular agricultural technology has characteristics and externality of public goods,the government participation is necessary in building the technology system of circular agriculture,in order to avoid "free rider" behavior in the consumption of public goods and internalize externality.We analyze the orientation of government's role in building the technology system of circular agriculture:the government is the leader,designer,organizer and regulator in building the technology system of circular agriculture;the government orientates the four roles precisely in building the technology system of circular agriculture,to ensure that they do not cross the line,but be indispensable all the while.
基金Supported by 2007 Environmental Protection Project of Jilin Provincial Department of Environmental Protection(2007-09)
文摘[Objective] The study aimed at analyzing the dynamic variation of land-use types of the constructed wetland before and after oil-field water irrigation based on 3S technology. [Method] At semi-arid and arid areas in the west of Jilin Province, water resource balance between the amount of oil-field water supply and ecological water requirement in the constructed wetland irrigated by oil-field water during 2001-2010 was investigated firstly. Afterwards, based on 3S technology, the partition and dynamic variation of land-use types of the constructed wetland before and after oil-field water irrigation in 2001, 2006, 2008 and 2010 were analyzed. [Result] The annual ecological water requirement of the constructed wetland from 2003 to 2010 varied from 1.62×106 to 2.24×106 m3, and the annual amount of oil-field water supply in the region changed from 2.12×106 to 2.84×106 m3, which showed that the supply amount of oil-field water could meet the basic ecological water requirement of the constructed wetland. Meanwhile, compared with 2001, the areas of water region and paddy field in 2010 increased by 2.3 and 10.0 times, and the areas of forest and marsh rose by 40.15% and 29.5.0% respectively. [Conclusion] Water shortage and ecological environment problem of arid and semi-arid areas had been improved by oil-field water irrigation.
文摘Softswitch technology integrates the su-periorities of both an intelligence net-work and the Internet, which embodiesits maturity and advancement. With ahierarchical network model, it effectivelysolves problems of evolution and convergenceof current communication networks. It also fol-