Modafinil, a new central stimulant, was synthesized from diphenylmethanol and 2-mercaptoacetic acid by a four-step reaction: condensation, chlorination, amination and then oxidation, in an overall yield of 58%.
文摘Modafinil, a new central stimulant, was synthesized from diphenylmethanol and 2-mercaptoacetic acid by a four-step reaction: condensation, chlorination, amination and then oxidation, in an overall yield of 58%.
