天疱疮是一种自身免疫性疾病,天疱疮发病率低,病情严重,如果未能得到及时有效的治疗,患者容易发生感染性休克死亡。因此对于深入理解天疱疮的发病机制而言,是至关重要的。然而目前对于天疱疮的病因机制还没有完全揭示出来。本研究从自...天疱疮是一种自身免疫性疾病,天疱疮发病率低,病情严重,如果未能得到及时有效的治疗,患者容易发生感染性休克死亡。因此对于深入理解天疱疮的发病机制而言,是至关重要的。然而目前对于天疱疮的病因机制还没有完全揭示出来。本研究从自身免疫、病毒、药物和饮食、细胞凋亡溶解等多个角度,探讨了这些因素在天疱疮的发病过程中的作用。Pemphigus is an autoimmune disease with a low incidence rate and severe condition. If not treated promptly and effectively, patients are prone to die from septic shock. Therefore, it is crucial to have a deep understanding of the pathogenesis of pemphigus. However, the etiology and mechanism of pemphigus have not been fully revealed yet. This study explores the roles of various factors such as autoimmunity, viruses, drugs and diet, and apoptosis and lysis in the pathogenesis of pemphigus from multiple perspectives.展开更多
文摘天疱疮是一种自身免疫性疾病,天疱疮发病率低,病情严重,如果未能得到及时有效的治疗,患者容易发生感染性休克死亡。因此对于深入理解天疱疮的发病机制而言,是至关重要的。然而目前对于天疱疮的病因机制还没有完全揭示出来。本研究从自身免疫、病毒、药物和饮食、细胞凋亡溶解等多个角度,探讨了这些因素在天疱疮的发病过程中的作用。Pemphigus is an autoimmune disease with a low incidence rate and severe condition. If not treated promptly and effectively, patients are prone to die from septic shock. Therefore, it is crucial to have a deep understanding of the pathogenesis of pemphigus. However, the etiology and mechanism of pemphigus have not been fully revealed yet. This study explores the roles of various factors such as autoimmunity, viruses, drugs and diet, and apoptosis and lysis in the pathogenesis of pemphigus from multiple perspectives.