Nail changes following upper extremity transplantation(UET)cannot be overlooked as they possess diagnostic and prognostic relevance in allotransplantation of upper limbs.This comprehensive review explores nail and nai...Nail changes following upper extremity transplantation(UET)cannot be overlooked as they possess diagnostic and prognostic relevance in allotransplantation of upper limbs.This comprehensive review explores nail and nail bed related changes encountered in UET recipients in the literature.The differential diagnosis of nail abnormalities in UET includes a wide range of systemic,local and iatrogenic conditions other than immune responses to the allograft.It requires interdisciplinary evaluation by primary transplant surgeons,pathologists,dermatologists and immunologists.The possible underlying mechanisms of nail pathology in UET and the management are discussed.It also underscores the importance of onychodystrophy and need for timely intervention and to improve outcomes in UET recipients.展开更多
目的:探讨在对手指旋转撕脱离断伤断指患者采用显微外科再植治疗的效果。方法:纳入2021年3月至2024年3月间我院收治的手指旋转撕脱离断伤断指患者96例,随机分为对照组和研究组(n=48),分别给予常规残端修整术治疗以及显微外科再植手术治...目的:探讨在对手指旋转撕脱离断伤断指患者采用显微外科再植治疗的效果。方法:纳入2021年3月至2024年3月间我院收治的手指旋转撕脱离断伤断指患者96例,随机分为对照组和研究组(n=48),分别给予常规残端修整术治疗以及显微外科再植手术治疗。治疗后6m对比患者治疗效果,治疗后6m测定两点辨别觉、断指指甲长度等,并采用手指关节总主动活动度(Total active movement,TAM)评估指关节功能,术前、术后1m采用日常生活能力(Activity of daily living,ADL)评分评价患者日常生活能力。结果:治疗后半年研究组患者总有效率为91.67%,相较于对照组的66.67%升高(χ^(2)=9.095,P<0.05);研究组患者临床各项指标恢复程度优于对照组(P<0.05);研究组患者关节功能恢复情况优于对照组(χ^(2)=9.466,P<0.05);治疗后1m两组患者日常生活能力评分均相较于治疗前上升,且研究组相较于对照组上升(P<0.05)。结论:采用显微外科再植治疗可有助于手指断面组织生长,并对远端指尖活动度、关节活动度起到改善作用,并提升日常生活能力。展开更多
文摘Nail changes following upper extremity transplantation(UET)cannot be overlooked as they possess diagnostic and prognostic relevance in allotransplantation of upper limbs.This comprehensive review explores nail and nail bed related changes encountered in UET recipients in the literature.The differential diagnosis of nail abnormalities in UET includes a wide range of systemic,local and iatrogenic conditions other than immune responses to the allograft.It requires interdisciplinary evaluation by primary transplant surgeons,pathologists,dermatologists and immunologists.The possible underlying mechanisms of nail pathology in UET and the management are discussed.It also underscores the importance of onychodystrophy and need for timely intervention and to improve outcomes in UET recipients.
文摘目的:探讨在对手指旋转撕脱离断伤断指患者采用显微外科再植治疗的效果。方法:纳入2021年3月至2024年3月间我院收治的手指旋转撕脱离断伤断指患者96例,随机分为对照组和研究组(n=48),分别给予常规残端修整术治疗以及显微外科再植手术治疗。治疗后6m对比患者治疗效果,治疗后6m测定两点辨别觉、断指指甲长度等,并采用手指关节总主动活动度(Total active movement,TAM)评估指关节功能,术前、术后1m采用日常生活能力(Activity of daily living,ADL)评分评价患者日常生活能力。结果:治疗后半年研究组患者总有效率为91.67%,相较于对照组的66.67%升高(χ^(2)=9.095,P<0.05);研究组患者临床各项指标恢复程度优于对照组(P<0.05);研究组患者关节功能恢复情况优于对照组(χ^(2)=9.466,P<0.05);治疗后1m两组患者日常生活能力评分均相较于治疗前上升,且研究组相较于对照组上升(P<0.05)。结论:采用显微外科再植治疗可有助于手指断面组织生长,并对远端指尖活动度、关节活动度起到改善作用,并提升日常生活能力。
