BACKGROUND Low anterior resection syndrome(LARS)is a prevalent and debilitating complication following sphincter-preserving surgery for rectal cancer.Evidence-based interventions for the concurrent psychological burde...BACKGROUND Low anterior resection syndrome(LARS)is a prevalent and debilitating complication following sphincter-preserving surgery for rectal cancer.Evidence-based interventions for the concurrent psychological burden are limited.Electroacupuncture has been proposed as a potential adjunctive therapy,but its psychological benefits remain inadequately studied.AIM To investigate the therapeutic effect of electroacupuncture on emotional recovery and gastrointestinal function in patients with moderate to severe LARS,and to explore its potential advantages in psychologically vulnerable subgroups.METHODS We conducted a retrospective,controlled study involving 100 patients with moderate to severe LARS(LARS score≥21)treated at two tertiary hospitals in China between January 2022 and December 2024.Patients received either standard postoperative care alone(n=50)or in combination with a standardized 4-week electroacupuncture protocol(n=50).Psychological and functional outcomes were assessed using validated instruments including Hospital Anxiety and Depression Scale(HADS),Body Image Scale(BIS),General Self-Efficacy Scale,Perceived Social Support Scale(PSSS),LARS score,and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 at four time points.The primary endpoint was emotional remission,defined as a≥3-point reduction in HADS-Anxiety subscale(HADS-A).Analyses included repeated-measures comparisons,Kaplan-Meier survival curves,Cox regression models,and subgroup-interaction testing.RESULTS At baseline,demographic,surgical,and psychosocial characteristics were comparable among groups.By week 4,patients receiving electroacupuncture demonstrated significantly greater reductions in anxiety(HADS-A:4.8±2.6 vs 7.3±3.0;P<0.001),depression,and body-image disturbance(BIS:8.7±3.6 vs 11.9±4.2;P<0.001),alongside enhanced coping capacity(Brief Coping Orientation to Problems Experienced),perceived social support(PSSS),and bowel function(LARS score).Emotional remission-defined as a≥3-point HADS-A reduction-was achieved more rapidly in the electroacupuncture group,as confirmed by Kaplan-Meier analysis(log-rank P<0.001;odds ratio=4.7).Multivariate Cox regression identified higher baseline LARS and BIS scores as independent predictors of delayed emotional recovery.Subgroup analyses revealed significantly amplified treatment benefits in patients with high baseline anxiety(HADS-A≥8),elevated body-image disturbance(BIS≥12),or low perceived social support(PSSS<60),with consistent interaction effects(P for interaction<0.05 across subgroups).CONCLUSION Electroacupuncture may accelerate emotional recovery and improve functional and psychosocial outcomes in patients with LARS.Its integration into postoperative care may offer particular benefits for psychologically vulnerable subgroups.展开更多
目的 观察针灸联合五行音乐对肺癌化疗患者癌因性疲乏和睡眠质量的影响。方法 将160例肺癌化疗患者用随机数字表法分为研究组和对照组,每组80例。对照组接受五行音乐治疗,研究组在对照组治疗基础上联合调益三焦针灸治疗。观察两组治疗...目的 观察针灸联合五行音乐对肺癌化疗患者癌因性疲乏和睡眠质量的影响。方法 将160例肺癌化疗患者用随机数字表法分为研究组和对照组,每组80例。对照组接受五行音乐治疗,研究组在对照组治疗基础上联合调益三焦针灸治疗。观察两组治疗前后改良Piper疲乏量表(Piper fatigue scale,PFS)评分、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)、欧洲癌症研究治疗组织生命质量评估问卷(European Organization for Research and Treatment of Cancerquality of life question naire 30-item core instrument, EORTC QLQ-C30)评分和睡眠时长的变化,比较两组住院时间。结果 治疗后,两组改良PFS各单项评分和PSQI明显降低(P<0.05),而睡眠时长和EORTC QLQ-C30评分明显升高(P<0.05)。研究组治疗后改良PFS各单项评分和PSQI低于对照组(P<0.05),睡眠时长和EORTC QLQ-C30评分高于对照组(P<0.05)。研究组住院时间短于对照组(P<0.05)。结论 针灸联合五行音乐更能缓解肺癌化疗患者的癌因性疲乏,改善睡眠质量,延长睡眠时间,提高生活质量,疗效优于单一五行音乐治疗。展开更多
文摘BACKGROUND Low anterior resection syndrome(LARS)is a prevalent and debilitating complication following sphincter-preserving surgery for rectal cancer.Evidence-based interventions for the concurrent psychological burden are limited.Electroacupuncture has been proposed as a potential adjunctive therapy,but its psychological benefits remain inadequately studied.AIM To investigate the therapeutic effect of electroacupuncture on emotional recovery and gastrointestinal function in patients with moderate to severe LARS,and to explore its potential advantages in psychologically vulnerable subgroups.METHODS We conducted a retrospective,controlled study involving 100 patients with moderate to severe LARS(LARS score≥21)treated at two tertiary hospitals in China between January 2022 and December 2024.Patients received either standard postoperative care alone(n=50)or in combination with a standardized 4-week electroacupuncture protocol(n=50).Psychological and functional outcomes were assessed using validated instruments including Hospital Anxiety and Depression Scale(HADS),Body Image Scale(BIS),General Self-Efficacy Scale,Perceived Social Support Scale(PSSS),LARS score,and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 at four time points.The primary endpoint was emotional remission,defined as a≥3-point reduction in HADS-Anxiety subscale(HADS-A).Analyses included repeated-measures comparisons,Kaplan-Meier survival curves,Cox regression models,and subgroup-interaction testing.RESULTS At baseline,demographic,surgical,and psychosocial characteristics were comparable among groups.By week 4,patients receiving electroacupuncture demonstrated significantly greater reductions in anxiety(HADS-A:4.8±2.6 vs 7.3±3.0;P<0.001),depression,and body-image disturbance(BIS:8.7±3.6 vs 11.9±4.2;P<0.001),alongside enhanced coping capacity(Brief Coping Orientation to Problems Experienced),perceived social support(PSSS),and bowel function(LARS score).Emotional remission-defined as a≥3-point HADS-A reduction-was achieved more rapidly in the electroacupuncture group,as confirmed by Kaplan-Meier analysis(log-rank P<0.001;odds ratio=4.7).Multivariate Cox regression identified higher baseline LARS and BIS scores as independent predictors of delayed emotional recovery.Subgroup analyses revealed significantly amplified treatment benefits in patients with high baseline anxiety(HADS-A≥8),elevated body-image disturbance(BIS≥12),or low perceived social support(PSSS<60),with consistent interaction effects(P for interaction<0.05 across subgroups).CONCLUSION Electroacupuncture may accelerate emotional recovery and improve functional and psychosocial outcomes in patients with LARS.Its integration into postoperative care may offer particular benefits for psychologically vulnerable subgroups.
文摘目的 观察针灸联合五行音乐对肺癌化疗患者癌因性疲乏和睡眠质量的影响。方法 将160例肺癌化疗患者用随机数字表法分为研究组和对照组,每组80例。对照组接受五行音乐治疗,研究组在对照组治疗基础上联合调益三焦针灸治疗。观察两组治疗前后改良Piper疲乏量表(Piper fatigue scale,PFS)评分、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)、欧洲癌症研究治疗组织生命质量评估问卷(European Organization for Research and Treatment of Cancerquality of life question naire 30-item core instrument, EORTC QLQ-C30)评分和睡眠时长的变化,比较两组住院时间。结果 治疗后,两组改良PFS各单项评分和PSQI明显降低(P<0.05),而睡眠时长和EORTC QLQ-C30评分明显升高(P<0.05)。研究组治疗后改良PFS各单项评分和PSQI低于对照组(P<0.05),睡眠时长和EORTC QLQ-C30评分高于对照组(P<0.05)。研究组住院时间短于对照组(P<0.05)。结论 针灸联合五行音乐更能缓解肺癌化疗患者的癌因性疲乏,改善睡眠质量,延长睡眠时间,提高生活质量,疗效优于单一五行音乐治疗。
