Mg/MgH_(2) has garnered significant attention primarily due to its abundant availability and high gravimetric density.Nevertheless,its practical implementation hindered by its high thermodynamic stability and sluggish...Mg/MgH_(2) has garnered significant attention primarily due to its abundant availability and high gravimetric density.Nevertheless,its practical implementation hindered by its high thermodynamic stability and sluggish kinetics.Fortunately,the introduction of transition metal single atom(TM SA)catalysts has emerged as an effective method to enhance the hydrogen storage properties of Mg/MgH_(2).Among these catalysts,the synergistic effect of nanoconfinement and TM SAs plays a pivotal role in the hydriding/dehydriding kinetics of Mg/MgH_(2).However,the effects of varying TM SAs interacting with N modified confined materials on H_(2) adsorption and desorption and underlying mechanisms remain enigmatic.Leveraging DFT calculations,we investigated the potential of combining TM SA catalysts with N-modified Carbon nanomaterials(CNT)to enhance the hydrogenation/dehydrogenation of Mg/MgH_(2).TM SA N-CNTs-Mg/MgH_(2) heterojunction systems encompassing ten 3d/4d transition metals were designed and constructed.We systematically investigated the impact of TM SA N-CNTs on the hydrogen absorption and desorption properties of Mg/MgH_(2) by examining parameters such as the electronic localization function(ELF),distorted charge density distributions,adsorption energies,dissociation energies,electronegativity,and the D-band center.Notably,the energy barriers for Mg/MgH_(2) hydrogenation and dehydrogenation were significantly reduced by 0.2-0.7 eV and 1.6-2.2 eV,respectively,through the catalytic promotion of TM SA N-CNTs.Herein,a novel“electronic-ropeway”effect was proposed to elucidate the underlying mechanism responsible for enhancing the hydrogen absorption and desorption kinetics in Mg/MgH_(2).Specifically,the contribution degree of TM SA N-CNTs and system electronegativity emerged as effective descriptors for predicting the reduced hydrogenation/dehydrogenation energy barriers.It is anticipated that elucidating the role of TM SA-N-CNTs will pave the way for developing innovative strategies to enhance the hydrogen absorption and desorption kinetics of Mg/MgH_(2) systems,thereby providing valuable design principles for the construction of novel Mg/MgH_(2) hydrogen storage materials.展开更多
Jinmudan,a new tea variety from Fujian Province has an excellent quality with a unique aroma like magnolia frogrance.To monitor the changes in the tea volatile compounds during the Jinmudan Oolong tea manufacturing(dr...Jinmudan,a new tea variety from Fujian Province has an excellent quality with a unique aroma like magnolia frogrance.To monitor the changes in the tea volatile compounds during the Jinmudan Oolong tea manufacturing(drying) process,the volatiles of tea samples were extracted and analyzed.Characteristic volatile compounds in Jinmudan Oolong tea were nerolidol,α-farnesene,linolenic acid,palmitic acid,indole,phenylacetaldehyde,cisjasmone,β-phenylethanol,etc.The content of nerolidol was the highest in four tested samples.The composition of the volatile compounds in microwave drying sample was simple,but its concentration was high,in which the main volatile compounds were alcohols and esters.The processing with combination of traditional drying craft and modern aroma-improvement technique could obviously improve the tea aroma,especially in level of epoxy linalool and jasmine lactone.展开更多
The Si Tian project,designed to utilize 60 telescopes distributed across multiple sites in China,is a next-generation timedomain survey initiative.As a pathfinder for the Si Tian project,the Mini-Si Tian(MST)has been ...The Si Tian project,designed to utilize 60 telescopes distributed across multiple sites in China,is a next-generation timedomain survey initiative.As a pathfinder for the Si Tian project,the Mini-Si Tian(MST)has been proposed and implemented to test the Si Tian’s brain and data pipeline,and to evaluate the feasibility of its technology and science cases.Mounted at the Xinglong Observatory,the MST project comprises three 30 cm telescopes and has been operated since 2022 November.Each telescope of the MST possesses a large field of view,covering 2°.29×1°.53 FOV,and is equipped withg',r'andi'filters,respectively.Acting as the pioneer of the forthcoming Si Tian project,the MST is dedicated to the discovery of variable stars,transients,and outburst events,and has already obtained some interesting scientific results.In this paper,we will summarize the first-two-year operation of the MST project.展开更多
Background During the transition period,cows are prone to negative energy balance,which can lead to a decline in production performance and health in severe cases.In recent years,it has been discovered that bile acids...Background During the transition period,cows are prone to negative energy balance,which can lead to a decline in production performance and health in severe cases.In recent years,it has been discovered that bile acids(BAs)can act not only as fat emulsifiers but also as signaling molecules to regulate body metabolism.Although BAs have been used to some extent in monogastric and aquatic animals,their role in ruminants,particularly in transition cows,remains unclear.Therefore,this study aimed to determine the effects of BAs on the production performance,milk and plasma fatty acid and BA composition,and fecal microbiota in transition dairy cows.Results Forty-six healthy transition Holstein dairy cows with similar conditions were randomly divided into two groups and supplemented with 0 or 20 g/d of BAs from 21 d before the expected calving to 21 d after calving.The production performance was tracked until 60 d after calving.The results indicated that BA supplementation significantly improved postpartum milk fat content and yields as well as the yields of unsaturated fatty acids,monounsaturated fatty acids,and polyunsaturated fatty acids in milk.There was a significant increase in the concentration of triglyceride and the proportion of C≤16 fatty acids in the plasma of cows supplemented with BAs,while the concentration of β-hydroxybutyrate and the proportion of C>16 fatty acids in the plasma decreased significantly.BA supplementation significantly altered the composition of the fecal bacterial community and increased the relative abundance of bacteria beneficial for BA metabolism and transformation(Romboutsia,Clostridium sensu_stricto_6,and Clostridium sensu_stricto_1).Functional prediction analysis showed that the relative abundance of bile salt hydrolase,7 α-hydroxysteroid dehydrogenase,and BA inducible E as well as the pathways related to BA metabolism also significantly increased in cows supplemented BAs.In addition,BA supplementation significantly altered the composition of plasma and fecal BAs,particularly increasing circulating secondary BA concentration,which might induce the complete oxidation of fatty acids in the liver and further reduce the concentration of β-hydroxybutyrate.Conclusions These findings highlight the potential benefits of BA supplementation in improving milk yields and quality,as well as influencing metabolic pathways in transition dairy cows.Meanwhile,further studies are needed to elucidate the underlying mechanisms and explore the broader implications of these results by using more tissue samples.展开更多
BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step method.The resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degradi...BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step method.The resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degrading Rhodamine B(RhB)unde mechanical vibrations,they exhibit superior activity compared to pure ZnO.The 40wt%ZnO/BiVO_(4)heterojunction composite displayed the highest activity,along with good stability and recyclability.The enhanced piezoelectric catalytic activity can be attributed to the form ation of an I-scheme heterojunction structure,which can effectively inhibit the electron-hole recombination.Furthermore,hole(h+)and superoxide radical(·O_(2)^(-))are proved to be the primary active species.Therefore,ZnO/BiVO_(4)stands as an efficient and stable piezoelectric catalyst with broad potential application in the field of environmental water pollution treatment.展开更多
SPAD(soil-plant analysis and development)计是一种快速、方便、非破坏性的诊断植物叶片相对叶绿素或氮含量的仪器,与传统的氮营养诊断方法相比,此仪器节省时间、劳力和资源。本试验通过未遮荫和遮荫的方法观察水稻冠层叶片SPAD值、...SPAD(soil-plant analysis and development)计是一种快速、方便、非破坏性的诊断植物叶片相对叶绿素或氮含量的仪器,与传统的氮营养诊断方法相比,此仪器节省时间、劳力和资源。本试验通过未遮荫和遮荫的方法观察水稻冠层叶片SPAD值、叶绿素含量、叶绿素荧光、光合参数、叶片厚度和比叶重(叶片干重除以叶片的面积)等生理形态指标的变化,建立SPAD值与光系统II(PSII)最大量子产量(Fv/Fm)之间的回归关系。结果表明,遮荫条件下,甬优9号(YY9)和丙9363(B9363)冠层叶片变薄、SPAD值、叶绿素a/b、比叶重、电子传递速率(ETR)降低,但快速光曲线的初始斜率无明显变化;同时,遮荫导致了叶片的呼吸速率、最大净光合(Pmax)、量子效率、光补偿点和饱和点降低,表明水稻叶片为适应弱光环境,降低光合能力、减少呼吸消耗,以增加对有限光能的利用。不同光照条件下,水稻冠层叶片SPAD值与PSII的Fv/Fm的回归方程呈指数式关系(YY9 R2=0.896;B9363 R2=0.833),表明SPAD计可以快速、无损、有效地评估水稻冠层叶片的光合作用进程,当SPAD值小于35时,其光合过程可能处于受损状态。展开更多
Objective: To explore the effectiveness of applying patient simulators combined with Internet Plus scenario simulation teaching models on intravenous (IV) infusion nursing education, and to provide scientific evidence...Objective: To explore the effectiveness of applying patient simulators combined with Internet Plus scenario simulation teaching models on intravenous (IV) infusion nursing education, and to provide scientific evidence for the implementation of advanced teaching models in future nursing education. Methods: Enrolled 60 nurses who took the IV infusion therapy training program in our hospital from January 2022 to December 2023 for research. 30 nurses who were trained in traditional teaching models from January to December 2022 were selected as the control group, and 30 nurses who were trained with simulation-based teaching models with methods including simulated patients, internet, online meetings which can be replayed and scenario simulation, etc. from January to December 2023 were selected as the experimental group. Evaluated the learning outcomes based on the Competency Inventory for Nursing Students (CINS), Problem-Solving Inventory (PSI), comprehensive learning ability, scientific research ability, and proficiency in the theoretical knowledge and practical skills of IV infusion therapy. Nursing quality, the incidence of IV infusion therapy complications and nurse satisfaction with different teaching models were also measured. Results: The scientific research ability, PSI scores, CINS scores, and comprehensive learning ability of the experimental group were better than those of the control group (P 0.05), and their assessment results of practical skills, nursing quality of IV infusion therapy during training, and satisfaction with teaching models were all better than those of the control group with statistical significance (P < 0.05). The incidence of IV infusion therapy complications in the experimental group was lower than that in the control group, indicating statistical significance (P < 0.05). Conclusions: Teaching models based on patient simulators combined with Internet Plus scenario simulation enable nursing students to learn more directly and practice at any time and in any place, and can improve their proficiency in IV infusion theoretical knowledge and skills (e.g. PICC catheterization), core competencies, problem-solving ability, comprehensive learning ability, scientific research ability and the ability to deal with complicated cases. Also, it helps provide high-quality nursing education, improve the nursing quality of IV therapy, reduce the incidence of related complications, and ensure the safety of patients with IV therapy.展开更多
Dear Editor,For the past few decades,mosquito-borne orthoflaviviruses,such as dengue virus,Zika virus,and West Nile virus(WNV),have posed significant threats to global public health.The Orthoflavivirus genus comprises...Dear Editor,For the past few decades,mosquito-borne orthoflaviviruses,such as dengue virus,Zika virus,and West Nile virus(WNV),have posed significant threats to global public health.The Orthoflavivirus genus comprises more than 70 viruses,many of which are responsible for a wide range of diseases in humans and animals,including febrile illnesses,encephalitis,and hemorrhagic febrile illness.These viruses are associated with approximately 400 million infections and 100 million symptomatic cases worldwide each year(Van Leur et al.,2021).Among them,Usutu virus(USUV)is an emerging pathogen classified alongside WNV within the Japanese encephalitis virus(JEV)serogroup of the Orthoflavivirus genus,the Flaviviridae family.USUV has spread from Africa to Europe since the late 20th century.It primarily causes central nervous system disorders in birds,with several large-scale mortality events recorded in Europe.USUV can also infect humans,it typically leads to neurological complications in rare cases(Roesch et al.,2019).展开更多
The national virology symposium of China,co-hosted biennially by the society and local research institutions,has now entered its 16th iteration.The 16th session,jointly hosted by Chinese Society for Virology-the virol...The national virology symposium of China,co-hosted biennially by the society and local research institutions,has now entered its 16th iteration.The 16th session,jointly hosted by Chinese Society for Virology-the virology division of the Chinese Society for Microbiology and the first hospital of Jilin University,took place in Changchun from August 15 to 17,2025.More than 800 participants attended the event,including renowned experts,scholars,and young scientists from institutions across the country(Fig.1).展开更多
BACKGROUND Older patients often experience thirst after general anesthesia for gastrointestinal surgery,particularly during the post-anesthesia care unit(PACU)phase.Thirst not only compromises patient comfort but also...BACKGROUND Older patients often experience thirst after general anesthesia for gastrointestinal surgery,particularly during the post-anesthesia care unit(PACU)phase.Thirst not only compromises patient comfort but also induces anxiety,which may hinder recovery.Although previous studies have addressed postoperative thirst,research specifically examining thirst experiences and nursing needs in older patients remains limited.AIM To explore thirst experiences and nursing needs of older PACU patients following gastrointestinal surgery,aiming to inform targeted interventions.METHODS This study employed a phenomenological approach within a qualitative research framework.A purposeful sampling method was used to select 12 older patients who underwent gastrointestinal surgery under general anesthesia at a tertiary hospital in Shanghai between November and December 2024.Data were collected through semi-structured interviews and analyzed using Colaizzi’s seven-step method.Themes were extracted from the interview data.RESULTS Analysis of the interview data identified four main themes and eight subthemes:(1)Intense sensations of thirst post-surgery(subjective experience of thirst and duration of thirst);(2)Emotional experiences of thirst-related discomfort(anxiety,irritability,and helplessness);(3)Practical challenges in relieving thirst(limitations of current interventions and nursing response time);and(4)Patient expectations of nursing care(desire for more timely interventions and expectation for more proactive attention from nursing staff).CONCLUSION Older patients frequently experience substantial thirst discomfort after gastrointestinal surgery under general anesthesia.A multidisciplinary perioperative intervention plan is essential to alleviate these symptoms and enhance postoperative comfort.展开更多
This study aims to increase the photoactivity of ZnSnO_(3)by modifying it with zeolitic imidazolate framework-8(ZIF-8).The composite catalyst was prepared by a straightforward hydrothermal method using ZnSnO_(3)as the...This study aims to increase the photoactivity of ZnSnO_(3)by modifying it with zeolitic imidazolate framework-8(ZIF-8).The composite catalyst was prepared by a straightforward hydrothermal method using ZnSnO_(3)as the zinc source.The in-situ generated ZnSnO_(3)/ZIF-8 composite exhibits a strong interaction between ZnSnO_(3)and ZIF-8,which benefits electron transfer.Band structure analysis shows that ZIF-8 has a higher conduction band and a lower valence band than ZnSnO_(3),and cannot form a typical heterojunction.However,defects in ZIF-8 may act as electron traps,accepting electrons from the conduction band of ZnSnO_(3).This atypical heterojunction results in the spatial separation of charge carriers within the composite.The transient photocurrent response,electrochemical impedance spectroscopy,and photoluminescence analysis confirmed this hypothesis.Meanwhile,ZIF-8 also plays a role in adsorbing dyes and concentrating reactants due to its extremely high specific surface area.Therefore,the ZnSnO_(3)/ZIF-8 composite exhibits significantly improved photocatalytic performance in Rhodamine B degradation.The degradation rate of the best sample was 10.4 times that of ZnSnO_(3).Active species capture experiments showed that holes and superoxide radicals were the main active species.Additionally,the ZnSnO_(3)/ZIF-8 composite showed enhanced photocatalytic activity in CO_(2)reduction.This study may show new insights into the design of efficient photocatalytic materials using metal-organic framework materials.展开更多
The occurrence and progression of liver cancer are closely associated with mitochondrial dysfunction.Mitochondria exhibit characteristics,such as decreased oxidative phosphorylation efficiency,abnormal accumulation of...The occurrence and progression of liver cancer are closely associated with mitochondrial dysfunction.Mitochondria exhibit characteristics,such as decreased oxidative phosphorylation efficiency,abnormal accumulation of reactive oxygen species in liver cancer and promoting tumor proliferation and drug resistance through the Warburg effect,as the core of energy metabolism and apoptosis regulation.Mutations in mitochondrial DNA(mtDNA)and dysregulation of mitochondrial autophagy(mitophagy)further enhance the invasive and metastatic capabilities of liver cancer.Current targeted therapeutic strategies focus on modulating the activity of respiratory chain complexes,regulating calcium homeostasis,repairing mtDNA,and activating mitochondrial apoptotic pathways.Although these approaches have shown therapeutic effects,challenges persist,such as tumor heterogeneity,insufficient drug specificity,and drug resistance.Future research needs to integrate the concept of precision medicine by focusing on breakthroughs in the molecular mechanisms underlying mitochondrial dysfunction,development of targeted delivery systems,optimization of combination therapy regimens,and screening of biomarkers to provide new pathways for individualized treatment.With advances in technology,targeting mitochondrial dysfunction is expected to become an important breakthrough for improving the prognosis of liver cancer.展开更多
BACKGROUND The two-way,three-stage psychological intervention for patients with dental pulp disease offers a reference for nursing interventions in such cases.AIM To examine the effects of a three-stage psychological ...BACKGROUND The two-way,three-stage psychological intervention for patients with dental pulp disease offers a reference for nursing interventions in such cases.AIM To examine the effects of a three-stage psychological intervention on psychological resilience and health behaviors.METHODS A total of 114 patients with dental pulp disease treated between December 2022 and December 2023 were allocated into two groups according to the random lottery method,with 57 patients in each group.The control group adopted the teaching method,while the observation group used a three-stage psychological intervention combined with the teaching method.We compared psychological resilience,coping strategies,dental fear,health behavior habits,and stigma between the two groups.RESULTS The intervention group showed significantly improved scores on the psychological resilience scale(Connor-Davidson Resilience Scale)(P<0.05);positive and negative response scores also improved after the intervention(P<0.05);significant differences were observed between the observation and control groups in the Chinese version of the Stouthard Dental Fear Scale(Dental Anxiety Inventory),the Social Impact Scale,and health behavior score(P<0.05).CONCLUSION Combining a three-stage psychological intervention with the back-teaching method effectively reduces dental fear and stigma in patients with dental pulp disease.It also improves psychological resilience,coping strategies,and health behavior habits,achieving significant results.展开更多
Objective To evaluate the impact of endometrial polyps(EP)on postoperative pregnancy outcomes in infertile women with endometriosis(EMs).Methods PubMed,Embase,The Cochrane Library,CNKI,VIP,SinoMed,and WanFang Data dat...Objective To evaluate the impact of endometrial polyps(EP)on postoperative pregnancy outcomes in infertile women with endometriosis(EMs).Methods PubMed,Embase,The Cochrane Library,CNKI,VIP,SinoMed,and WanFang Data databases were searched to include clinical studies on the effect of EP on pregnancy outcomes in patients with EMs,published before August 31,2020.A meta-analysis was performed using Rev Man 5.3 software after two investigators independently screened the literature,extracted information,and evaluated the risk of bias of the included studies.Results The meta-analysis included ten studies(651 and 1,040 in the combined EP and uncomplicated EP groups,respectively).The spontaneous pregnancy rate,clinical pregnancy rate,and live birth rate were significantly lower in the group with combined EPs than in the group without combined EPs[Odd’s ratio(OR)=0.63,95%confidence interval(CI):0.50–0.80,P=0.0001;OR=0.63,95%CI:0.48–0.84,P=0.001;OR=0.63,95%CI:0.42–0.96,P=0.03],and the rate of embryonic abortion was significantly higher than that in the uncomplicated EP group[OR=3.10,95%CI:1.52–6.32,P=0.002].Conclusion EP may adversely affect pregnancy outcomes in patients with infertility and EMs.Even after surgical treatment,EP can still reduce natural pregnancy,clinical pregnancy,and live birth rates in infertile women with EMs and increase the risk of embryo arrest in these women.展开更多
BACKGROUND The theory of planned behavior(TPB)and whole-course nursing are mainly used for patients with cancer,chronic diseases,and other conditions that require longterm rehabilitation.There are few studies on disea...BACKGROUND The theory of planned behavior(TPB)and whole-course nursing are mainly used for patients with cancer,chronic diseases,and other conditions that require longterm rehabilitation.There are few studies on diseases,such as acute abdomen,for which patients urgently need surgery.Owing to the particularity of acute abdomen and limited preoperative preparation,patients and their families may not fully realize the significance of postoperative rehabilitation and the development of good treatment behavior.Therefore,this study used acute appendicitis as an entry point to explore the influence of TPB and the whole-process management of acute abdominal disease.AIM To examine the impact of TPB-based whole-process management on postoperative rehabilitation and complications in patients with acute appendicitis.METHODS A total of 180 patients enrolled between July 2023 and June 2024 were randomly assigned via computer-generated sequence into two groups in a 1:1 ratio,with 90 cases each.In the control group,17 cases withdrew,leaving 73 cases that ultimately received routine care.In the experimental group,6 cases withdrew,leaving 84 cases that ultimately received full-process TPB management.The postoperative rehabilitation and complications were compared between the two groups.RESULTS The first exhaust time,bowel sound recovery time,first defecation time,first postoperative ground movement time,and postoperative hospital stay were shorter in the experimental group than in the control group(P<0.05).The Visual Analog Scale scores of the experimental group were lower than those of the control group at 6 hours,12 hours,24 hours,and 48 hours postoperatively(P<0.05).The total incidence of complications was lower in the experimental group than in the control group(P<0.05).The total satisfaction rate of the experimental group was higher than that of the control group(P<0.05).In both groups,patients 48 hours postoperatively had lower Self-Rating Anxiety Scale scores than those preoperatively.The Self-Rating Anxiety Scale score of the experimental group at 48 hours was lower than that of the control group(P<0.05).CONCLUSION Whole-process management based on the TPB can shorten the postoperative recovery time in patients with acute appendicitis and reduce the incidence of pain and complications.展开更多
基金financed by the National Key Research and Development Program of China [grants number 2023YFB3809101]the National Natural Science Foundation of China [grants number 52471225, 52271212, 52201250]+1 种基金the Natural Science Foundation of Hebei Province [grants number E2018502054]the Fundamental Research Funds for the Central Universities [grants number 2023MS148]
文摘Mg/MgH_(2) has garnered significant attention primarily due to its abundant availability and high gravimetric density.Nevertheless,its practical implementation hindered by its high thermodynamic stability and sluggish kinetics.Fortunately,the introduction of transition metal single atom(TM SA)catalysts has emerged as an effective method to enhance the hydrogen storage properties of Mg/MgH_(2).Among these catalysts,the synergistic effect of nanoconfinement and TM SAs plays a pivotal role in the hydriding/dehydriding kinetics of Mg/MgH_(2).However,the effects of varying TM SAs interacting with N modified confined materials on H_(2) adsorption and desorption and underlying mechanisms remain enigmatic.Leveraging DFT calculations,we investigated the potential of combining TM SA catalysts with N-modified Carbon nanomaterials(CNT)to enhance the hydrogenation/dehydrogenation of Mg/MgH_(2).TM SA N-CNTs-Mg/MgH_(2) heterojunction systems encompassing ten 3d/4d transition metals were designed and constructed.We systematically investigated the impact of TM SA N-CNTs on the hydrogen absorption and desorption properties of Mg/MgH_(2) by examining parameters such as the electronic localization function(ELF),distorted charge density distributions,adsorption energies,dissociation energies,electronegativity,and the D-band center.Notably,the energy barriers for Mg/MgH_(2) hydrogenation and dehydrogenation were significantly reduced by 0.2-0.7 eV and 1.6-2.2 eV,respectively,through the catalytic promotion of TM SA N-CNTs.Herein,a novel“electronic-ropeway”effect was proposed to elucidate the underlying mechanism responsible for enhancing the hydrogen absorption and desorption kinetics in Mg/MgH_(2).Specifically,the contribution degree of TM SA N-CNTs and system electronegativity emerged as effective descriptors for predicting the reduced hydrogenation/dehydrogenation energy barriers.It is anticipated that elucidating the role of TM SA-N-CNTs will pave the way for developing innovative strategies to enhance the hydrogen absorption and desorption kinetics of Mg/MgH_(2) systems,thereby providing valuable design principles for the construction of novel Mg/MgH_(2) hydrogen storage materials.
基金supported by the rural science and technology innovation fund project of technology division from Ningbo city science and technology bureau (No.201001C8002011,201002C1011003)
文摘Jinmudan,a new tea variety from Fujian Province has an excellent quality with a unique aroma like magnolia frogrance.To monitor the changes in the tea volatile compounds during the Jinmudan Oolong tea manufacturing(drying) process,the volatiles of tea samples were extracted and analyzed.Characteristic volatile compounds in Jinmudan Oolong tea were nerolidol,α-farnesene,linolenic acid,palmitic acid,indole,phenylacetaldehyde,cisjasmone,β-phenylethanol,etc.The content of nerolidol was the highest in four tested samples.The composition of the volatile compounds in microwave drying sample was simple,but its concentration was high,in which the main volatile compounds were alcohols and esters.The processing with combination of traditional drying craft and modern aroma-improvement technique could obviously improve the tea aroma,especially in level of epoxy linalool and jasmine lactone.
基金supported by the National Key R&D Program of China(grant No.2023YFA1608304 and No.2023YFA1608300)the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0550100 and XDB0550000)the National Natural Science Foundation of China(NSFC,grant Nos.12090041,12090040,11903054,12422303,and 12261141690)。
文摘The Si Tian project,designed to utilize 60 telescopes distributed across multiple sites in China,is a next-generation timedomain survey initiative.As a pathfinder for the Si Tian project,the Mini-Si Tian(MST)has been proposed and implemented to test the Si Tian’s brain and data pipeline,and to evaluate the feasibility of its technology and science cases.Mounted at the Xinglong Observatory,the MST project comprises three 30 cm telescopes and has been operated since 2022 November.Each telescope of the MST possesses a large field of view,covering 2°.29×1°.53 FOV,and is equipped withg',r'andi'filters,respectively.Acting as the pioneer of the forthcoming Si Tian project,the MST is dedicated to the discovery of variable stars,transients,and outburst events,and has already obtained some interesting scientific results.In this paper,we will summarize the first-two-year operation of the MST project.
基金supported by the National Center of Technology Innovation for Dairy(No.2024-JSGG-021)the National Natural Science Foundation of China(No.32102570)the Key Research and Development Project of Ningxia(No.2024BBF01006).
文摘Background During the transition period,cows are prone to negative energy balance,which can lead to a decline in production performance and health in severe cases.In recent years,it has been discovered that bile acids(BAs)can act not only as fat emulsifiers but also as signaling molecules to regulate body metabolism.Although BAs have been used to some extent in monogastric and aquatic animals,their role in ruminants,particularly in transition cows,remains unclear.Therefore,this study aimed to determine the effects of BAs on the production performance,milk and plasma fatty acid and BA composition,and fecal microbiota in transition dairy cows.Results Forty-six healthy transition Holstein dairy cows with similar conditions were randomly divided into two groups and supplemented with 0 or 20 g/d of BAs from 21 d before the expected calving to 21 d after calving.The production performance was tracked until 60 d after calving.The results indicated that BA supplementation significantly improved postpartum milk fat content and yields as well as the yields of unsaturated fatty acids,monounsaturated fatty acids,and polyunsaturated fatty acids in milk.There was a significant increase in the concentration of triglyceride and the proportion of C≤16 fatty acids in the plasma of cows supplemented with BAs,while the concentration of β-hydroxybutyrate and the proportion of C>16 fatty acids in the plasma decreased significantly.BA supplementation significantly altered the composition of the fecal bacterial community and increased the relative abundance of bacteria beneficial for BA metabolism and transformation(Romboutsia,Clostridium sensu_stricto_6,and Clostridium sensu_stricto_1).Functional prediction analysis showed that the relative abundance of bile salt hydrolase,7 α-hydroxysteroid dehydrogenase,and BA inducible E as well as the pathways related to BA metabolism also significantly increased in cows supplemented BAs.In addition,BA supplementation significantly altered the composition of plasma and fecal BAs,particularly increasing circulating secondary BA concentration,which might induce the complete oxidation of fatty acids in the liver and further reduce the concentration of β-hydroxybutyrate.Conclusions These findings highlight the potential benefits of BA supplementation in improving milk yields and quality,as well as influencing metabolic pathways in transition dairy cows.Meanwhile,further studies are needed to elucidate the underlying mechanisms and explore the broader implications of these results by using more tissue samples.
基金financially supported by the National Natural Science Foundation of China(No.22272151)Public Welfare Technology Application Research Project of Jinhua City,China(No.2023-4-022)。
文摘BiVO_(4)porous spheres modified by ZnO were designed and synthesized using a facile two-step method.The resulting ZnO/BiVO_(4)composite catalysts have shown remarkable efficiency as piezoelectric catalysts for degrading Rhodamine B(RhB)unde mechanical vibrations,they exhibit superior activity compared to pure ZnO.The 40wt%ZnO/BiVO_(4)heterojunction composite displayed the highest activity,along with good stability and recyclability.The enhanced piezoelectric catalytic activity can be attributed to the form ation of an I-scheme heterojunction structure,which can effectively inhibit the electron-hole recombination.Furthermore,hole(h+)and superoxide radical(·O_(2)^(-))are proved to be the primary active species.Therefore,ZnO/BiVO_(4)stands as an efficient and stable piezoelectric catalyst with broad potential application in the field of environmental water pollution treatment.
文摘Objective: To explore the effectiveness of applying patient simulators combined with Internet Plus scenario simulation teaching models on intravenous (IV) infusion nursing education, and to provide scientific evidence for the implementation of advanced teaching models in future nursing education. Methods: Enrolled 60 nurses who took the IV infusion therapy training program in our hospital from January 2022 to December 2023 for research. 30 nurses who were trained in traditional teaching models from January to December 2022 were selected as the control group, and 30 nurses who were trained with simulation-based teaching models with methods including simulated patients, internet, online meetings which can be replayed and scenario simulation, etc. from January to December 2023 were selected as the experimental group. Evaluated the learning outcomes based on the Competency Inventory for Nursing Students (CINS), Problem-Solving Inventory (PSI), comprehensive learning ability, scientific research ability, and proficiency in the theoretical knowledge and practical skills of IV infusion therapy. Nursing quality, the incidence of IV infusion therapy complications and nurse satisfaction with different teaching models were also measured. Results: The scientific research ability, PSI scores, CINS scores, and comprehensive learning ability of the experimental group were better than those of the control group (P 0.05), and their assessment results of practical skills, nursing quality of IV infusion therapy during training, and satisfaction with teaching models were all better than those of the control group with statistical significance (P < 0.05). The incidence of IV infusion therapy complications in the experimental group was lower than that in the control group, indicating statistical significance (P < 0.05). Conclusions: Teaching models based on patient simulators combined with Internet Plus scenario simulation enable nursing students to learn more directly and practice at any time and in any place, and can improve their proficiency in IV infusion theoretical knowledge and skills (e.g. PICC catheterization), core competencies, problem-solving ability, comprehensive learning ability, scientific research ability and the ability to deal with complicated cases. Also, it helps provide high-quality nursing education, improve the nursing quality of IV therapy, reduce the incidence of related complications, and ensure the safety of patients with IV therapy.
基金funded by grants from the National Key Research and Development Program of China(2022YFD1801900)National Natural Science Foundation of China(32272976&32302848)+3 种基金Sichuan Provincial Department of Science and Technology international scientific and technological innovation cooperation(2022YFH0026)the earmarked fund for China Agricultural Research System(CARS-42-17)Program Sichuan Veterinary Medicine and Drug Innovation Group of China Agricultural Research System(SCCXTD-2021-18)the Innovation and Demonstration of Industry and Education Integration in Feed Industrial Chain Transformation and Upgradation,Sichuan Province,China.
文摘Dear Editor,For the past few decades,mosquito-borne orthoflaviviruses,such as dengue virus,Zika virus,and West Nile virus(WNV),have posed significant threats to global public health.The Orthoflavivirus genus comprises more than 70 viruses,many of which are responsible for a wide range of diseases in humans and animals,including febrile illnesses,encephalitis,and hemorrhagic febrile illness.These viruses are associated with approximately 400 million infections and 100 million symptomatic cases worldwide each year(Van Leur et al.,2021).Among them,Usutu virus(USUV)is an emerging pathogen classified alongside WNV within the Japanese encephalitis virus(JEV)serogroup of the Orthoflavivirus genus,the Flaviviridae family.USUV has spread from Africa to Europe since the late 20th century.It primarily causes central nervous system disorders in birds,with several large-scale mortality events recorded in Europe.USUV can also infect humans,it typically leads to neurological complications in rare cases(Roesch et al.,2019).
文摘The national virology symposium of China,co-hosted biennially by the society and local research institutions,has now entered its 16th iteration.The 16th session,jointly hosted by Chinese Society for Virology-the virology division of the Chinese Society for Microbiology and the first hospital of Jilin University,took place in Changchun from August 15 to 17,2025.More than 800 participants attended the event,including renowned experts,scholars,and young scientists from institutions across the country(Fig.1).
文摘BACKGROUND Older patients often experience thirst after general anesthesia for gastrointestinal surgery,particularly during the post-anesthesia care unit(PACU)phase.Thirst not only compromises patient comfort but also induces anxiety,which may hinder recovery.Although previous studies have addressed postoperative thirst,research specifically examining thirst experiences and nursing needs in older patients remains limited.AIM To explore thirst experiences and nursing needs of older PACU patients following gastrointestinal surgery,aiming to inform targeted interventions.METHODS This study employed a phenomenological approach within a qualitative research framework.A purposeful sampling method was used to select 12 older patients who underwent gastrointestinal surgery under general anesthesia at a tertiary hospital in Shanghai between November and December 2024.Data were collected through semi-structured interviews and analyzed using Colaizzi’s seven-step method.Themes were extracted from the interview data.RESULTS Analysis of the interview data identified four main themes and eight subthemes:(1)Intense sensations of thirst post-surgery(subjective experience of thirst and duration of thirst);(2)Emotional experiences of thirst-related discomfort(anxiety,irritability,and helplessness);(3)Practical challenges in relieving thirst(limitations of current interventions and nursing response time);and(4)Patient expectations of nursing care(desire for more timely interventions and expectation for more proactive attention from nursing staff).CONCLUSION Older patients frequently experience substantial thirst discomfort after gastrointestinal surgery under general anesthesia.A multidisciplinary perioperative intervention plan is essential to alleviate these symptoms and enhance postoperative comfort.
基金supported by the National Natural Science Foundation of China(Nos.22172144 and 22272151)the Public Welfare Technology Application Research Project of Jinhua City(No.2023-4-022)the Key Research and Development Program of Zhejiang Province(No.2023C03148).
文摘This study aims to increase the photoactivity of ZnSnO_(3)by modifying it with zeolitic imidazolate framework-8(ZIF-8).The composite catalyst was prepared by a straightforward hydrothermal method using ZnSnO_(3)as the zinc source.The in-situ generated ZnSnO_(3)/ZIF-8 composite exhibits a strong interaction between ZnSnO_(3)and ZIF-8,which benefits electron transfer.Band structure analysis shows that ZIF-8 has a higher conduction band and a lower valence band than ZnSnO_(3),and cannot form a typical heterojunction.However,defects in ZIF-8 may act as electron traps,accepting electrons from the conduction band of ZnSnO_(3).This atypical heterojunction results in the spatial separation of charge carriers within the composite.The transient photocurrent response,electrochemical impedance spectroscopy,and photoluminescence analysis confirmed this hypothesis.Meanwhile,ZIF-8 also plays a role in adsorbing dyes and concentrating reactants due to its extremely high specific surface area.Therefore,the ZnSnO_(3)/ZIF-8 composite exhibits significantly improved photocatalytic performance in Rhodamine B degradation.The degradation rate of the best sample was 10.4 times that of ZnSnO_(3).Active species capture experiments showed that holes and superoxide radicals were the main active species.Additionally,the ZnSnO_(3)/ZIF-8 composite showed enhanced photocatalytic activity in CO_(2)reduction.This study may show new insights into the design of efficient photocatalytic materials using metal-organic framework materials.
基金supported by the National Natural Science Foundation of China(Grant No.81860653)Qiankehe Foundation[Grant No.QN(2025)383].
文摘The occurrence and progression of liver cancer are closely associated with mitochondrial dysfunction.Mitochondria exhibit characteristics,such as decreased oxidative phosphorylation efficiency,abnormal accumulation of reactive oxygen species in liver cancer and promoting tumor proliferation and drug resistance through the Warburg effect,as the core of energy metabolism and apoptosis regulation.Mutations in mitochondrial DNA(mtDNA)and dysregulation of mitochondrial autophagy(mitophagy)further enhance the invasive and metastatic capabilities of liver cancer.Current targeted therapeutic strategies focus on modulating the activity of respiratory chain complexes,regulating calcium homeostasis,repairing mtDNA,and activating mitochondrial apoptotic pathways.Although these approaches have shown therapeutic effects,challenges persist,such as tumor heterogeneity,insufficient drug specificity,and drug resistance.Future research needs to integrate the concept of precision medicine by focusing on breakthroughs in the molecular mechanisms underlying mitochondrial dysfunction,development of targeted delivery systems,optimization of combination therapy regimens,and screening of biomarkers to provide new pathways for individualized treatment.With advances in technology,targeting mitochondrial dysfunction is expected to become an important breakthrough for improving the prognosis of liver cancer.
基金ORCID number:Qing-Feng Wang 0009-0009-4579-7133Ying Wu 0009-0007-2061-739X。
文摘BACKGROUND The two-way,three-stage psychological intervention for patients with dental pulp disease offers a reference for nursing interventions in such cases.AIM To examine the effects of a three-stage psychological intervention on psychological resilience and health behaviors.METHODS A total of 114 patients with dental pulp disease treated between December 2022 and December 2023 were allocated into two groups according to the random lottery method,with 57 patients in each group.The control group adopted the teaching method,while the observation group used a three-stage psychological intervention combined with the teaching method.We compared psychological resilience,coping strategies,dental fear,health behavior habits,and stigma between the two groups.RESULTS The intervention group showed significantly improved scores on the psychological resilience scale(Connor-Davidson Resilience Scale)(P<0.05);positive and negative response scores also improved after the intervention(P<0.05);significant differences were observed between the observation and control groups in the Chinese version of the Stouthard Dental Fear Scale(Dental Anxiety Inventory),the Social Impact Scale,and health behavior score(P<0.05).CONCLUSION Combining a three-stage psychological intervention with the back-teaching method effectively reduces dental fear and stigma in patients with dental pulp disease.It also improves psychological resilience,coping strategies,and health behavior habits,achieving significant results.
文摘Objective To evaluate the impact of endometrial polyps(EP)on postoperative pregnancy outcomes in infertile women with endometriosis(EMs).Methods PubMed,Embase,The Cochrane Library,CNKI,VIP,SinoMed,and WanFang Data databases were searched to include clinical studies on the effect of EP on pregnancy outcomes in patients with EMs,published before August 31,2020.A meta-analysis was performed using Rev Man 5.3 software after two investigators independently screened the literature,extracted information,and evaluated the risk of bias of the included studies.Results The meta-analysis included ten studies(651 and 1,040 in the combined EP and uncomplicated EP groups,respectively).The spontaneous pregnancy rate,clinical pregnancy rate,and live birth rate were significantly lower in the group with combined EPs than in the group without combined EPs[Odd’s ratio(OR)=0.63,95%confidence interval(CI):0.50–0.80,P=0.0001;OR=0.63,95%CI:0.48–0.84,P=0.001;OR=0.63,95%CI:0.42–0.96,P=0.03],and the rate of embryonic abortion was significantly higher than that in the uncomplicated EP group[OR=3.10,95%CI:1.52–6.32,P=0.002].Conclusion EP may adversely affect pregnancy outcomes in patients with infertility and EMs.Even after surgical treatment,EP can still reduce natural pregnancy,clinical pregnancy,and live birth rates in infertile women with EMs and increase the risk of embryo arrest in these women.
文摘BACKGROUND The theory of planned behavior(TPB)and whole-course nursing are mainly used for patients with cancer,chronic diseases,and other conditions that require longterm rehabilitation.There are few studies on diseases,such as acute abdomen,for which patients urgently need surgery.Owing to the particularity of acute abdomen and limited preoperative preparation,patients and their families may not fully realize the significance of postoperative rehabilitation and the development of good treatment behavior.Therefore,this study used acute appendicitis as an entry point to explore the influence of TPB and the whole-process management of acute abdominal disease.AIM To examine the impact of TPB-based whole-process management on postoperative rehabilitation and complications in patients with acute appendicitis.METHODS A total of 180 patients enrolled between July 2023 and June 2024 were randomly assigned via computer-generated sequence into two groups in a 1:1 ratio,with 90 cases each.In the control group,17 cases withdrew,leaving 73 cases that ultimately received routine care.In the experimental group,6 cases withdrew,leaving 84 cases that ultimately received full-process TPB management.The postoperative rehabilitation and complications were compared between the two groups.RESULTS The first exhaust time,bowel sound recovery time,first defecation time,first postoperative ground movement time,and postoperative hospital stay were shorter in the experimental group than in the control group(P<0.05).The Visual Analog Scale scores of the experimental group were lower than those of the control group at 6 hours,12 hours,24 hours,and 48 hours postoperatively(P<0.05).The total incidence of complications was lower in the experimental group than in the control group(P<0.05).The total satisfaction rate of the experimental group was higher than that of the control group(P<0.05).In both groups,patients 48 hours postoperatively had lower Self-Rating Anxiety Scale scores than those preoperatively.The Self-Rating Anxiety Scale score of the experimental group at 48 hours was lower than that of the control group(P<0.05).CONCLUSION Whole-process management based on the TPB can shorten the postoperative recovery time in patients with acute appendicitis and reduce the incidence of pain and complications.
