为探究鳞杯伞子实体多糖(Clitocybe squamulosa fruiting body polysaccharide,CSFP)对玉米淀粉理化及结构特性影响,分别向玉米淀粉中加入基于干基质0、2%、4%、6%、8%的CSFP,研究其糊化特性、流变性能、微观结构、红外光谱和质构特性...为探究鳞杯伞子实体多糖(Clitocybe squamulosa fruiting body polysaccharide,CSFP)对玉米淀粉理化及结构特性影响,分别向玉米淀粉中加入基于干基质0、2%、4%、6%、8%的CSFP,研究其糊化特性、流变性能、微观结构、红外光谱和质构特性。结果表明:CSFP能够延缓玉米淀粉的糊化,具体表现为随着CSFP添加量的增加,玉米淀粉糊化的峰值黏度、最低黏度、最终黏度、崩解黏度、回生黏度均下降,而糊化温度有所升高。静态流变结果显示玉米淀粉糊和复配体系均呈现剪切稀释的假塑性流体,且流体指数(n)和稠度系数(K)分别出现随CSFP添加量的增加而上升和下降的趋势;动态流变结果显示玉米淀粉糊和复配体系呈弱凝胶行为。通过扫描电镜对样品的微观结构进行观察,发现CSFP的加入使得样品内部结构逐渐松散,空隙变大。红外光谱扫描结果表明,形成的复配体系中未形成新的基团,添加CSFP后,淀粉结构的短程有序程度上升。研究结果表明,CSFP使得玉米淀粉糊的硬度、弹性、内聚性、咀嚼性和胶黏性均有所下降,以期为当前易吞咽食品的开发提供参考。展开更多
Agricultural drought,a prolonged disaster with widespread impacts,exerts tremendous pressure on farm household activities,agricultural production,and economic development.The western region of Jilin Province,China,loc...Agricultural drought,a prolonged disaster with widespread impacts,exerts tremendous pressure on farm household activities,agricultural production,and economic development.The western region of Jilin Province,China,located in a semi-arid zone,where persistents drought exacerbates ecological fragility.With a larger proportion of its population living in rural areas,the life and production activities of households are particularly susceptible to drought-related challenges.This study focuses on the western part of Jilin Province,utilizing remote sensing data to calculate the temperature vegetation dryness index(TVDI)as a soil moisture monitoring indicator for drought assessment.The livelihood vulnerability index(LVI)and the improved LVI-Intergovernmental Panel on Climate Change(IPCC)index are employed to comprehensively assess the livelihood vulnerability of communes in the region and the impact of drought conditions on farmers'livelihood vulnerability.The results reveal a spatial trend of increasing drought severity from northeast to southwest,with temporally minor fluctuations observed in drought levels from 2005 to 2022.Livelihood vulnerability results indicate significant spatial and temporal variations,with education,health,food,and water playing key roles.Correlation analysis indicates a strong relationship between TVDI and LVI,highlighting the detrimental impact of drought on farmers'livelihoods.The study aims to provide a scientific foundation for managing livelihood vulnerability in the western part of Jilin Province and similar arid areas.Additionally,it seeks to offer strategic recommendations for policymakers to mitigate the adverse effects of drought,thereby reducing farmers'vulnerability and fostering sustainable socio-economic development.展开更多
在神经性毒剂的识别中,相似性谱图搜索是公认的可靠谱图注释方法,然而该方法受限于参考标准谱图库,无法实现库外谱图注释,因而对库外未知化合物的鉴定耗时长且人工判定误差大。本文提出了一种基于深度卷积神经网络的神经性毒剂及其相关...在神经性毒剂的识别中,相似性谱图搜索是公认的可靠谱图注释方法,然而该方法受限于参考标准谱图库,无法实现库外谱图注释,因而对库外未知化合物的鉴定耗时长且人工判定误差大。本文提出了一种基于深度卷积神经网络的神经性毒剂及其相关化合物的特征基团结构分类模型,并在中央分析数据库(Official Central Analytical Database,OCAD)数据集上完成了模型的训练和测试。构建平衡训练数据集后,模型在测试集上的精确率、召回率和F1分数分别为96.89%、96.88%和96.88%。测试结果表明,其在OCAD数据集上精确率为98.78%,在美国国家标准与技术研究院(National Institute of Standards and Technology,NIST)数据集上精确率为95.73%。该方法在预测神经性毒剂特征基团结构时不依赖于标准谱图库,不借助预先建立的规则、程序或峰值匹配,可为实验人员提供辅助决策。展开更多
目的研究基因重组人生长激素治疗特发性矮小症患儿的效果及对IGF-1水平、糖脂代谢的影响。方法选取2021年1月至2024年1月本院收治的120例特发性矮小症患儿作为研究对象,将其随机分为对照组和观察组,各60例。对照组采用常规治疗,观察组...目的研究基因重组人生长激素治疗特发性矮小症患儿的效果及对IGF-1水平、糖脂代谢的影响。方法选取2021年1月至2024年1月本院收治的120例特发性矮小症患儿作为研究对象,将其随机分为对照组和观察组,各60例。对照组采用常规治疗,观察组在对照组基础上增加基因重组人生长激素治疗。比较两组的临床疗效、生长指标、胰岛素样生长因子-1(IGF-1)、胰岛素样生长因子结合蛋白3(IGFBP-3)水平、糖脂代谢指标及不良反应发生情况。结果观察组的治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组的身高、生长速度均高于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组的IGF-1、IGFBP-3水平高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的空腹血糖(FBG)、餐后2 h血糖(2 h PG)、总胆固醇(TC)及低密度脂蛋白胆固醇(LDL-C)水平比较,差异无统计学意义(P>0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论基因重组人生长激素治疗特发性矮小症患儿的效果显著,可促进身高生长,提高IGF-1水平,不影响糖脂代谢过程,且治疗安全性良好。展开更多
文摘为探究鳞杯伞子实体多糖(Clitocybe squamulosa fruiting body polysaccharide,CSFP)对玉米淀粉理化及结构特性影响,分别向玉米淀粉中加入基于干基质0、2%、4%、6%、8%的CSFP,研究其糊化特性、流变性能、微观结构、红外光谱和质构特性。结果表明:CSFP能够延缓玉米淀粉的糊化,具体表现为随着CSFP添加量的增加,玉米淀粉糊化的峰值黏度、最低黏度、最终黏度、崩解黏度、回生黏度均下降,而糊化温度有所升高。静态流变结果显示玉米淀粉糊和复配体系均呈现剪切稀释的假塑性流体,且流体指数(n)和稠度系数(K)分别出现随CSFP添加量的增加而上升和下降的趋势;动态流变结果显示玉米淀粉糊和复配体系呈弱凝胶行为。通过扫描电镜对样品的微观结构进行观察,发现CSFP的加入使得样品内部结构逐渐松散,空隙变大。红外光谱扫描结果表明,形成的复配体系中未形成新的基团,添加CSFP后,淀粉结构的短程有序程度上升。研究结果表明,CSFP使得玉米淀粉糊的硬度、弹性、内聚性、咀嚼性和胶黏性均有所下降,以期为当前易吞咽食品的开发提供参考。
基金Under the auspices of Basic Construction Funds of Jilin Province in 2024 and 2023(No.2024C021-3,2023C030-1)Foundation of the Education Department of Jilin Province(No.JJKH20250317KJ)National Natural Science Foundation of China(No.42071223,42471223)。
文摘Agricultural drought,a prolonged disaster with widespread impacts,exerts tremendous pressure on farm household activities,agricultural production,and economic development.The western region of Jilin Province,China,located in a semi-arid zone,where persistents drought exacerbates ecological fragility.With a larger proportion of its population living in rural areas,the life and production activities of households are particularly susceptible to drought-related challenges.This study focuses on the western part of Jilin Province,utilizing remote sensing data to calculate the temperature vegetation dryness index(TVDI)as a soil moisture monitoring indicator for drought assessment.The livelihood vulnerability index(LVI)and the improved LVI-Intergovernmental Panel on Climate Change(IPCC)index are employed to comprehensively assess the livelihood vulnerability of communes in the region and the impact of drought conditions on farmers'livelihood vulnerability.The results reveal a spatial trend of increasing drought severity from northeast to southwest,with temporally minor fluctuations observed in drought levels from 2005 to 2022.Livelihood vulnerability results indicate significant spatial and temporal variations,with education,health,food,and water playing key roles.Correlation analysis indicates a strong relationship between TVDI and LVI,highlighting the detrimental impact of drought on farmers'livelihoods.The study aims to provide a scientific foundation for managing livelihood vulnerability in the western part of Jilin Province and similar arid areas.Additionally,it seeks to offer strategic recommendations for policymakers to mitigate the adverse effects of drought,thereby reducing farmers'vulnerability and fostering sustainable socio-economic development.
文摘在神经性毒剂的识别中,相似性谱图搜索是公认的可靠谱图注释方法,然而该方法受限于参考标准谱图库,无法实现库外谱图注释,因而对库外未知化合物的鉴定耗时长且人工判定误差大。本文提出了一种基于深度卷积神经网络的神经性毒剂及其相关化合物的特征基团结构分类模型,并在中央分析数据库(Official Central Analytical Database,OCAD)数据集上完成了模型的训练和测试。构建平衡训练数据集后,模型在测试集上的精确率、召回率和F1分数分别为96.89%、96.88%和96.88%。测试结果表明,其在OCAD数据集上精确率为98.78%,在美国国家标准与技术研究院(National Institute of Standards and Technology,NIST)数据集上精确率为95.73%。该方法在预测神经性毒剂特征基团结构时不依赖于标准谱图库,不借助预先建立的规则、程序或峰值匹配,可为实验人员提供辅助决策。
文摘目的研究基因重组人生长激素治疗特发性矮小症患儿的效果及对IGF-1水平、糖脂代谢的影响。方法选取2021年1月至2024年1月本院收治的120例特发性矮小症患儿作为研究对象,将其随机分为对照组和观察组,各60例。对照组采用常规治疗,观察组在对照组基础上增加基因重组人生长激素治疗。比较两组的临床疗效、生长指标、胰岛素样生长因子-1(IGF-1)、胰岛素样生长因子结合蛋白3(IGFBP-3)水平、糖脂代谢指标及不良反应发生情况。结果观察组的治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组的身高、生长速度均高于对照组,差异具有统计学意义(P<0.05)。治疗后,观察组的IGF-1、IGFBP-3水平高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组的空腹血糖(FBG)、餐后2 h血糖(2 h PG)、总胆固醇(TC)及低密度脂蛋白胆固醇(LDL-C)水平比较,差异无统计学意义(P>0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论基因重组人生长激素治疗特发性矮小症患儿的效果显著,可促进身高生长,提高IGF-1水平,不影响糖脂代谢过程,且治疗安全性良好。
