摘要
目的探讨非对称回波的最小二乘估算法迭代水脂分离技术(IDEAL-IQ)定量骨髓脂肪含量及铁含量在鉴别诊断再生障碍性贫血(AA)及骨髓增生异常综合征(MDS)中的应用价值。方法纳入AA患者44例(AA组)、MDS患者25例(MDS组)、健康对照组志愿者28例(对照组),定量测定右侧髂骨骨髓脂肪含量及铁含量,通过计算组间相关系数(ICC)对3位数据检测者进行一致性分析,非参数检验比较AA组、MDS组及对照组之间骨髓脂肪含量及R2*值的差异。结果AA组骨髓脂肪含量高于MDS组及对照组,MDS组脂肪含量低于对照组,差异有统计学意义(P<0.05);AA组、MDS组及对照组骨髓铁含量差异无统计学意义(P>0.05)。结论磁共振成像IDEAL-IQ技术可根据骨髓脂肪含量的变化从影像学角度无创性的对初步鉴别诊断再障及骨髓增生异常综合征提供有效的技术支持,通过评估骨髓脂肪含量,辅助临床进行治疗方案的选择。
Objective To evaluate the application value of IDEAL-IQ quantitative assessment of bone marrow fat content and iron content in differentiating between aplastic anemia(AA)and myelodysplastic syndrome(MDS).Methods A total of 44 patients with AA(AA group),25 patients with MDS(MDS group),and 28 healthy volunteers(control group)were included.We quantitatively measured the bone marrow fat content and iron content of the right iliac bone.Consistency among three data assessors was analyzed using the interclass correlation coefficient(ICC).Non-parametric tests were employed to compare differences in bone marrow fat content and R2*values among the AA,MDS,and control groups,P<0.05 considered statistically significant.Results The AA group exhibited a significantly higher bone marrow fat content compared to the MDS group and the control group,with significant differences(P<0.05).No statistically significant differences were found in bone marrow iron content among the AA group,MDS group,and control group(P>0.05).Conclusion The IDEAL-IQ technique of magnetic resonance imaging can provide effective technical support for the preliminary differential diagnosis of aplastic disorder and myelodysplastic syndrome from the imaging perspective according to the changes of bone marrow fat content.By evaluating bone marrow fat content,it can assist the clinical selection of treatment.
作者
田燕
许亚萍
崔运福
王丹
曹新山
TIAN Yan;XU Yaping;CUI Yunfu;WANG Dan;CAO Xinshan(Department of Radiology,Binzhou Medical University Hospital,Binzhou 256600,China)
出处
《分子影像学杂志》
2025年第2期223-228,共6页
Journal of Molecular Imaging
基金
山东省科技发展计划(2010GSF10265)
滨州医学院附属医院科技计划项目(BY2021KJ36)。
