目的 探讨成人重症监护室(intensive care unit,ICU)患者亚谵妄综合征(subsyndromal delirium,SSD)的危险因素,构建风险预测模型并进行验证。方法 纳入2022年6月—2024年1月山东省某三级甲等综合医院的ICU患者380例,将其中70%(n=266)作...目的 探讨成人重症监护室(intensive care unit,ICU)患者亚谵妄综合征(subsyndromal delirium,SSD)的危险因素,构建风险预测模型并进行验证。方法 纳入2022年6月—2024年1月山东省某三级甲等综合医院的ICU患者380例,将其中70%(n=266)作为建模组,30%(n=114)作为验证组,通过比较发生SSD的患者与未发生SSD的患者一般资料、疾病与治疗、实验室检查指标等,筛选出危险因素,并使用Logistic回归构建风险预测模型。结果 构建的风险预测模型包括年龄(OR=1.023)、急性生理与慢性健康状况评分Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)(OR=1.093)、重症监护疼痛观察工具(critical care pain observation tool,CPOT)评分(OR=2.216)、机械通气时间(OR=1.003)、约束(OR=2.615)、脓毒症(OR=2.081)6个风险因素。模型预测效果分析结果显示,Calibration图示校准曲线与理想曲线接近重合;受试者工作特征(receiver operating characteristic,ROC)曲线下面积为0.816,预测临界值85分。模型内部验证结果显示,Calibration图示校准曲线接近理想曲线,ROC曲线下面积0.808。结论 成人ICU患者亚谵妄风险预测模型具有较好的一致性及预测效能,可为临床早期筛查亚谵妄综合征并进行干预提供依据。展开更多
Objective To study the current situation and corresponding characteristics of internet pharmacy services and summarize their core connotations,and to make some suggestions for their future development based on nationa...Objective To study the current situation and corresponding characteristics of internet pharmacy services and summarize their core connotations,and to make some suggestions for their future development based on national policies.Methods The literature of the last 20 years that fully or partially matched the theme of internet pharmacy services in China was studied to summarize the status of research and development of remote pharmacy services by combining the web survey method.Results and Conclusion China’s internet pharmacy services include online consultation,science education,information enquiry,follow-up and intervention,and other functions.The main service providers are medical institutions,Internet enterprises,and online drug sales platforms.Internet pharmacy services can improve patients’compliance with medication and the convenience of medical treatment,which better play the role of pharmacists.However,they also face problems such as the varying service qualities,the small number of users,the difficulty in popularizing services in remote areas,and the lack of supervision and protection of patients’rights.展开更多
Objective To quantitatively analyze the policy of centralized drug procurement centralized drug procurement in order to provide reference for the subsequent policy formulation and improvement.Methods Text mining metho...Objective To quantitatively analyze the policy of centralized drug procurement centralized drug procurement in order to provide reference for the subsequent policy formulation and improvement.Methods Text mining method was used to process 15 centralized drugs procurement policies issued at the national level during 2015-2022,and a PMC index evaluation model of centralized drug procurement policies was established.Then,15 centralized drug procurement policies were quantitatively analyzed from the overall and comparative perspective through an evaluation model.Results and Conclusion The average PMC index of 15 centralized drug procurement policies was 6.95,which was acceptable on the whole.Among them,eight were excellent and seven were acceptable.As to the first-order variables,the centralized drugs procurement policy still lacks incentives and constraints.The comparative results show that there are differences in the content and structure of policies,but they are strongly related to each other.Chinese centralized drug procurement policy has been basically formed,which is closely related to medical insurance and medical policies.However,it is still necessary to pay attention to the structure of the policy to ensure the elaboration of the policy content.展开更多
Objective To study the increasing use of sports and fitness APPs against the background of national fitness and post-epidemic era,and to provide some suggestions for the development of sports and fitness APPs.Methods ...Objective To study the increasing use of sports and fitness APPs against the background of national fitness and post-epidemic era,and to provide some suggestions for the development of sports and fitness APPs.Methods Literature survey and mathematical statistics were used to define the concept of sports and fitness APPs,and their characteristics and advantages were investigated.Then,their problems were pointed out.Results and Conclusion The existing problems include some APPs favoring female users,single function,and slightly backward profit model.Some countermeasures such as enriching course types,taking into account all categories of users,expanding more functions,improving service quality,broadening profit channels,and improving marketing level are put forward.This can provide theoretical basis for the operation of sports and fitness APPs and better popularize the culture of national fitness.展开更多
Objective To study the inheritance and innovation of traditional Chinese medicine,and to offer an insight for the public.Methods Literature review,data retrieval and systematic analysis were used to elaborate and summ...Objective To study the inheritance and innovation of traditional Chinese medicine,and to offer an insight for the public.Methods Literature review,data retrieval and systematic analysis were used to elaborate and summarize the influence of changes in related classification and policy reform of traditional Chinese medicine(TCM)registration on its inheritance and innovation.The study was carried out in the context of the TCM registration related classification and policy reform and evolution on TCM inheritance and innovation.Results and Conclusion TCM registration plays an important role in the inheritance and innovation of TCM,which greatly influences on its inheritance and innovation.The reform of new registration classification respects the law of TCM research and development,reflecting the establishment of the review and approval system in line with the characteristics of TCM inheritance,which promotes the research and development of new drugs.The establishment of the review and approval system also accelerates the marketing transformation of new traditional Chinese medicine.TCM innovation should attach importance to clinical value orientation and improve the scientific connotation of TCM.Meanwhile,the advantage of China’s accession to ICH,PIC/S and other international drug certification organizations should be taken to speed up the construction of international mutual recognition of TCM standardization system,which can provide a broader path for the inheritance and innovation of TCM in the new era.展开更多
Objective To analyze the current situation of drug regulation after introducing the new policy for China’s online pharmacy,and to provide reference for the regulation of online pharmacy based on the international exp...Objective To analyze the current situation of drug regulation after introducing the new policy for China’s online pharmacy,and to provide reference for the regulation of online pharmacy based on the international experience.Methods Through literature research and comparative analysis,the history of policies for online pharmacy in China was investigated,and the current situation and problems of regulation for online pharmacy were explored.Results and Conclusion It is found that the body,basis and behavior of online prescription drug supervision in China should be improved.Combining experience in regulating online prescription drug at home and abroad,we provide some suggestions for the implementation of China’s online prescription drug policy by establishing a government-led multiple regulatory mechanism,standardizing the access qualifications for enterprises with business in online prescription drugs,improving the prescription inquiry and review system,and paying attention to consumer needs.展开更多
文摘目的 探讨成人重症监护室(intensive care unit,ICU)患者亚谵妄综合征(subsyndromal delirium,SSD)的危险因素,构建风险预测模型并进行验证。方法 纳入2022年6月—2024年1月山东省某三级甲等综合医院的ICU患者380例,将其中70%(n=266)作为建模组,30%(n=114)作为验证组,通过比较发生SSD的患者与未发生SSD的患者一般资料、疾病与治疗、实验室检查指标等,筛选出危险因素,并使用Logistic回归构建风险预测模型。结果 构建的风险预测模型包括年龄(OR=1.023)、急性生理与慢性健康状况评分Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)(OR=1.093)、重症监护疼痛观察工具(critical care pain observation tool,CPOT)评分(OR=2.216)、机械通气时间(OR=1.003)、约束(OR=2.615)、脓毒症(OR=2.081)6个风险因素。模型预测效果分析结果显示,Calibration图示校准曲线与理想曲线接近重合;受试者工作特征(receiver operating characteristic,ROC)曲线下面积为0.816,预测临界值85分。模型内部验证结果显示,Calibration图示校准曲线接近理想曲线,ROC曲线下面积0.808。结论 成人ICU患者亚谵妄风险预测模型具有较好的一致性及预测效能,可为临床早期筛查亚谵妄综合征并进行干预提供依据。
基金2021 General Scientific Research Project of Liaoning Provincial Department of Education(No.LJKR0298)Liaoning Provincial Social Science Planning。
文摘Objective To study the current situation and corresponding characteristics of internet pharmacy services and summarize their core connotations,and to make some suggestions for their future development based on national policies.Methods The literature of the last 20 years that fully or partially matched the theme of internet pharmacy services in China was studied to summarize the status of research and development of remote pharmacy services by combining the web survey method.Results and Conclusion China’s internet pharmacy services include online consultation,science education,information enquiry,follow-up and intervention,and other functions.The main service providers are medical institutions,Internet enterprises,and online drug sales platforms.Internet pharmacy services can improve patients’compliance with medication and the convenience of medical treatment,which better play the role of pharmacists.However,they also face problems such as the varying service qualities,the small number of users,the difficulty in popularizing services in remote areas,and the lack of supervision and protection of patients’rights.
文摘Objective To quantitatively analyze the policy of centralized drug procurement centralized drug procurement in order to provide reference for the subsequent policy formulation and improvement.Methods Text mining method was used to process 15 centralized drugs procurement policies issued at the national level during 2015-2022,and a PMC index evaluation model of centralized drug procurement policies was established.Then,15 centralized drug procurement policies were quantitatively analyzed from the overall and comparative perspective through an evaluation model.Results and Conclusion The average PMC index of 15 centralized drug procurement policies was 6.95,which was acceptable on the whole.Among them,eight were excellent and seven were acceptable.As to the first-order variables,the centralized drugs procurement policy still lacks incentives and constraints.The comparative results show that there are differences in the content and structure of policies,but they are strongly related to each other.Chinese centralized drug procurement policy has been basically formed,which is closely related to medical insurance and medical policies.However,it is still necessary to pay attention to the structure of the policy to ensure the elaboration of the policy content.
基金Liaoning Provincial Social Science Planning Fund Office(2019)(L19BGL034).
文摘Objective To study the increasing use of sports and fitness APPs against the background of national fitness and post-epidemic era,and to provide some suggestions for the development of sports and fitness APPs.Methods Literature survey and mathematical statistics were used to define the concept of sports and fitness APPs,and their characteristics and advantages were investigated.Then,their problems were pointed out.Results and Conclusion The existing problems include some APPs favoring female users,single function,and slightly backward profit model.Some countermeasures such as enriching course types,taking into account all categories of users,expanding more functions,improving service quality,broadening profit channels,and improving marketing level are put forward.This can provide theoretical basis for the operation of sports and fitness APPs and better popularize the culture of national fitness.
文摘Objective To study the inheritance and innovation of traditional Chinese medicine,and to offer an insight for the public.Methods Literature review,data retrieval and systematic analysis were used to elaborate and summarize the influence of changes in related classification and policy reform of traditional Chinese medicine(TCM)registration on its inheritance and innovation.The study was carried out in the context of the TCM registration related classification and policy reform and evolution on TCM inheritance and innovation.Results and Conclusion TCM registration plays an important role in the inheritance and innovation of TCM,which greatly influences on its inheritance and innovation.The reform of new registration classification respects the law of TCM research and development,reflecting the establishment of the review and approval system in line with the characteristics of TCM inheritance,which promotes the research and development of new drugs.The establishment of the review and approval system also accelerates the marketing transformation of new traditional Chinese medicine.TCM innovation should attach importance to clinical value orientation and improve the scientific connotation of TCM.Meanwhile,the advantage of China’s accession to ICH,PIC/S and other international drug certification organizations should be taken to speed up the construction of international mutual recognition of TCM standardization system,which can provide a broader path for the inheritance and innovation of TCM in the new era.
文摘Objective To analyze the current situation of drug regulation after introducing the new policy for China’s online pharmacy,and to provide reference for the regulation of online pharmacy based on the international experience.Methods Through literature research and comparative analysis,the history of policies for online pharmacy in China was investigated,and the current situation and problems of regulation for online pharmacy were explored.Results and Conclusion It is found that the body,basis and behavior of online prescription drug supervision in China should be improved.Combining experience in regulating online prescription drug at home and abroad,we provide some suggestions for the implementation of China’s online prescription drug policy by establishing a government-led multiple regulatory mechanism,standardizing the access qualifications for enterprises with business in online prescription drugs,improving the prescription inquiry and review system,and paying attention to consumer needs.
