目的 探讨成人重症监护室(intensive care unit,ICU)患者亚谵妄综合征(subsyndromal delirium,SSD)的危险因素,构建风险预测模型并进行验证。方法 纳入2022年6月—2024年1月山东省某三级甲等综合医院的ICU患者380例,将其中70%(n=266)作...目的 探讨成人重症监护室(intensive care unit,ICU)患者亚谵妄综合征(subsyndromal delirium,SSD)的危险因素,构建风险预测模型并进行验证。方法 纳入2022年6月—2024年1月山东省某三级甲等综合医院的ICU患者380例,将其中70%(n=266)作为建模组,30%(n=114)作为验证组,通过比较发生SSD的患者与未发生SSD的患者一般资料、疾病与治疗、实验室检查指标等,筛选出危险因素,并使用Logistic回归构建风险预测模型。结果 构建的风险预测模型包括年龄(OR=1.023)、急性生理与慢性健康状况评分Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)(OR=1.093)、重症监护疼痛观察工具(critical care pain observation tool,CPOT)评分(OR=2.216)、机械通气时间(OR=1.003)、约束(OR=2.615)、脓毒症(OR=2.081)6个风险因素。模型预测效果分析结果显示,Calibration图示校准曲线与理想曲线接近重合;受试者工作特征(receiver operating characteristic,ROC)曲线下面积为0.816,预测临界值85分。模型内部验证结果显示,Calibration图示校准曲线接近理想曲线,ROC曲线下面积0.808。结论 成人ICU患者亚谵妄风险预测模型具有较好的一致性及预测效能,可为临床早期筛查亚谵妄综合征并进行干预提供依据。展开更多
Objective To study the current situation and corresponding characteristics of internet pharmacy services and summarize their core connotations,and to make some suggestions for their future development based on nationa...Objective To study the current situation and corresponding characteristics of internet pharmacy services and summarize their core connotations,and to make some suggestions for their future development based on national policies.Methods The literature of the last 20 years that fully or partially matched the theme of internet pharmacy services in China was studied to summarize the status of research and development of remote pharmacy services by combining the web survey method.Results and Conclusion China’s internet pharmacy services include online consultation,science education,information enquiry,follow-up and intervention,and other functions.The main service providers are medical institutions,Internet enterprises,and online drug sales platforms.Internet pharmacy services can improve patients’compliance with medication and the convenience of medical treatment,which better play the role of pharmacists.However,they also face problems such as the varying service qualities,the small number of users,the difficulty in popularizing services in remote areas,and the lack of supervision and protection of patients’rights.展开更多
文摘目的 探讨成人重症监护室(intensive care unit,ICU)患者亚谵妄综合征(subsyndromal delirium,SSD)的危险因素,构建风险预测模型并进行验证。方法 纳入2022年6月—2024年1月山东省某三级甲等综合医院的ICU患者380例,将其中70%(n=266)作为建模组,30%(n=114)作为验证组,通过比较发生SSD的患者与未发生SSD的患者一般资料、疾病与治疗、实验室检查指标等,筛选出危险因素,并使用Logistic回归构建风险预测模型。结果 构建的风险预测模型包括年龄(OR=1.023)、急性生理与慢性健康状况评分Ⅱ(acute physiology and chronic health evaluationⅡ,APACHEⅡ)(OR=1.093)、重症监护疼痛观察工具(critical care pain observation tool,CPOT)评分(OR=2.216)、机械通气时间(OR=1.003)、约束(OR=2.615)、脓毒症(OR=2.081)6个风险因素。模型预测效果分析结果显示,Calibration图示校准曲线与理想曲线接近重合;受试者工作特征(receiver operating characteristic,ROC)曲线下面积为0.816,预测临界值85分。模型内部验证结果显示,Calibration图示校准曲线接近理想曲线,ROC曲线下面积0.808。结论 成人ICU患者亚谵妄风险预测模型具有较好的一致性及预测效能,可为临床早期筛查亚谵妄综合征并进行干预提供依据。
基金2021 General Scientific Research Project of Liaoning Provincial Department of Education(No.LJKR0298)Liaoning Provincial Social Science Planning。
文摘Objective To study the current situation and corresponding characteristics of internet pharmacy services and summarize their core connotations,and to make some suggestions for their future development based on national policies.Methods The literature of the last 20 years that fully or partially matched the theme of internet pharmacy services in China was studied to summarize the status of research and development of remote pharmacy services by combining the web survey method.Results and Conclusion China’s internet pharmacy services include online consultation,science education,information enquiry,follow-up and intervention,and other functions.The main service providers are medical institutions,Internet enterprises,and online drug sales platforms.Internet pharmacy services can improve patients’compliance with medication and the convenience of medical treatment,which better play the role of pharmacists.However,they also face problems such as the varying service qualities,the small number of users,the difficulty in popularizing services in remote areas,and the lack of supervision and protection of patients’rights.
