The underground thermal fluid is one of the significant factors controlling the formation and quality of reservoirs.The Huangliu Formation(N_(1)h)in YF1 area of the central depression belt in the Yinggehai Basin,South...The underground thermal fluid is one of the significant factors controlling the formation and quality of reservoirs.The Huangliu Formation(N_(1)h)in YF1 area of the central depression belt in the Yinggehai Basin,South China Sea,is characterized by intense thermal fluid activities related to mud diapir and large-scale shallow-water gravity flow deposits.The multi-episodic invasion of high-temperature and CO_(2)-rich thermal fluid into the formation induces complex water-rock reaction during diagenetic pro-cess,providing a preferable investigation opportunity for revealing how thermal fluid affects reservoir quality.This study characterizes the reservoirs in the formation through core and thin section analyses as well as physical property test.The reservoirs are dominated by fine-grained sandstone characterized by medium porosity(15.2-21.3%)and lower permeability(0.56-15.75mD).Based on an analysis of casting thin section,cathode luminescence(CL),scanning electron microscope(SEM),carbon and oxygen isotope,inclusion test,and electron-probe microanalysis(EPMA),we systematically investigate the diagenetic patterns and pore evolution process for the reservoirs in the formation.The episodic invasion of thermal fluid occurred approximately 0.4 Ma ago plays an important role in controlling reservoir development:The CO_(2)-rich formation water induces massive late-stage dissolution,resulting in a higher proportion of dissolved pores(38.7-46.4%),which improves the porosity of reservoirs at a depth of 2600-3100 m.Nevertheless,the late dissolution together with carbonate cementation occurred in closed diagenetic system blocks most seepage channels.Furthermore,the relatively high level clay mineral transformation in the YF1 area leads to a higher content of authigenic illite(44-62%)in the formation.Massive authigenic illite severely blocks the pore throats in fine sandstone,reducing permeability.This study offers an insight to the understanding of mud diapir-derived thermal fluid affecting and controlling the quality of reservoirs in some areas of the Yinggehai Basin.展开更多
The conventional Kibble–Zurek mechanism,describing driven dynamics across critical points based on the adiabatic-impulse scenario(AIS),has attracted broad attention.However,the driven dynamics at the tricritical poin...The conventional Kibble–Zurek mechanism,describing driven dynamics across critical points based on the adiabatic-impulse scenario(AIS),has attracted broad attention.However,the driven dynamics at the tricritical point with two independent relevant directions have not been adequately studied.Here,we employ the time-dependent variational principle to study the driven critical dynamics at a one-dimensional supersymmetric Ising tricritical point.For the relevant direction along the Ising critical line,the AIS apparently breaks down.Nevertheless,we find that the critical dynamics can still be described by finite-time scaling in which the driving rate has a dimension of r_(μ)=z+1/v_(μ)with z and v_(μ)being the dynamic exponent and correlation length exponent in this direction,respectively.For driven dynamics along another direction,the driving rate has a dimension of r_(p)=z+1/v_(p)with v_(p)being another correlation length exponent.Our work brings a new fundamental perspective into nonequilibrium critical dynamics near the tricritical point,which could be realized in programmable quantum processors in Rydberg atomic systems.展开更多
Satellite observations are widely used to estimate the concentrations of surface air pollutants,but the temporal coverage of these datasets is relatively short.To overcome this limitation,we propose a wide-deep ensemb...Satellite observations are widely used to estimate the concentrations of surface air pollutants,but the temporal coverage of these datasets is relatively short.To overcome this limitation,we propose a wide-deep ensemble machine learning framework to reconstruct the fine particulate matter(particulate matter lower than 2.5 lm(PM_(2.5)))dataset of East Asia(EA)over the past four decades(1981-2020).The results indicate that the framework effectively leveraged the advantages of satellite observations(higher accuracy)and model-based estimations(longer temporal coverage)of surface air pollutants.The reconstructed PM_(2.5) concentrations agreed well with the ground measurements,with coefficient of determination(R^(2))and root-mean-square error(RMSE)values of 0.99 and 1.38 lg m^(3),respectively,which outperformed the satellite-based PM_(2.5) estimates.As more ground measurements were incorporated into the model for training,the average RMSE in Japan and the Korean Peninsula decreased to 0.83 and 1.50 lg m^(3),respectively.Simultaneously,on the basis of the reconstructed datasets,we investigated the exposure level to PM_(2.5) in EA from 1981 to 2020.Since 2000,the increase in anthropogenic emissions has substantially worsened the air quality in EA,and nearly 50% of the population resided in areas where the annual average PM_(2.5) concentrations exceeded 50 lg m^(3) from 2009 to 2010.Despite the implementation of various mitigation strategies by local authorities to lower the ambient PM_(2.5) concentrations,the entire exposure level in EA is still implausible to meet the World Health Organization(WHO)air quality guidelines.In addition,population aging and climate change have the potential to increase PM_(2.5) exposure risk in the future.For policy-makers in EA,it is essential to consider the effects of these factors and develop more effective mitigation strategies that aim to lessen the health impact associated with PM_(2.5) exposure.展开更多
The third member of Shahejie Formation(also referred to as Sha 3 Member)in Dongpu Depression,China,a volatile,low-permeability oil reservoir with complex fluid compositions,is subjected to high temperature and high pr...The third member of Shahejie Formation(also referred to as Sha 3 Member)in Dongpu Depression,China,a volatile,low-permeability oil reservoir with complex fluid compositions,is subjected to high temperature and high pressure(HPHT),which poses significant challenges to conventional water injection.To elucidate flow mechanisms and optimize development strategies,this study integrates constant-rate mercury injection(CRMI),nuclear magnetic resonance(NMR),and HPHT three-phase oil/gas/water relative permeability experiments to analyze pore-throat structures,movable fluid characteristics,and relative permeability.The CRMI results indicate that the reservoir exhibits low porosity and low permeability,with dominant throat radius ranging from 0.6 to 5.0μm,and mean pore-throat radius ratio ranging from 40.303 to 278.320,demonstrating significant microscopic heterogeneity.The NMR results reveal that water-alternating-gas(WAG)injection enhances oil recovery by 16.28%(Sample W1)and 13.52%(Sample W2)compared to conventional water injection,primarily due to the gas phase's low viscosity and high mobility,enabling access to micropores unreachable by water phases.The HPHT three-phase relative permeability tests demonstrate positive correlations between saturation and relative permeability,with oil permeability significantly influenced by three-phase saturation and rock wettability.These findings establish a microscopic seepage model for optimizing enhanced oil recovery(EOR)strategies in volatile reservoirs.展开更多
The reduction of global carbon emissions and the achievement of carbon neutrality have become the focus of addressing climate change and global warming.Electrochemical CO_(2) reduction(CO_(2)RR),as a technology that c...The reduction of global carbon emissions and the achievement of carbon neutrality have become the focus of addressing climate change and global warming.Electrochemical CO_(2) reduction(CO_(2)RR),as a technology that can efficiently convert CO_(2) into value-added products,is receiving widespread attention.This article reviews the current research status of Cu/metal oxide heterostructures in the field of electrochemical reduction of CO_(2).The review first introduces the importance of electrochemical reduction of CO_(2) and the application potential of Cu/metal oxide heterostructures in this field.Subsequently,a comprehensive discussion is presented on the exploration of various Cu/metal oxide heterostructures and their corresponding structure-performance relationship,with particular emphasis on the catalysts'activity,selectivity,stability and the nature of active sites.Lastly,the review provides an overview of the current research challenges and future development trends in this field.展开更多
Driven critical dynamics in quantum phase transitions holds significant theoretical importance,and also has practical applications in fast-developing quantum devices.While scaling corrections have been shown to play i...Driven critical dynamics in quantum phase transitions holds significant theoretical importance,and also has practical applications in fast-developing quantum devices.While scaling corrections have been shown to play important roles in fully characterizing equilibrium quantum criticality,their impact on nonequilibrium critical dynamics has not been extensively explored.In this work,we investigate the driven critical dynamics in a two-dimensional quantum Heisenberg model.We find that in this model the scaling corrections arising from both finite system size and finite driving rate must be incorporated into the finite-time scaling form in order to properly describe the nonequilibrium scaling behaviors.In addition,improved scaling relations are obtained from the expansion of the full scaling form.We numerically verify these scaling forms and improved scaling relations for different starting states using the nonequilibrium quantum Monte Carlo algorithm.展开更多
Acupuncture is widely used to treat functional dyspepsia with satisfactory outcomes. Combination of the He and Mu acupoints is commonly used and has a synergistic effect on functional dyspepsia; however, its underlyin...Acupuncture is widely used to treat functional dyspepsia with satisfactory outcomes. Combination of the He and Mu acupoints is commonly used and has a synergistic effect on functional dyspepsia; however, its underlying mechanisms remain unclear. Therefore, a randomized controlled parallel clinical trial is currently underway at Chengdu University of Traditional Chinese Medicine, China. This trial is designed to explore the efficacy of and central responses to the He-Mu point combination in patients with functional dyspepsia using functional magnetic resonance imaging. A total of 105 patients with functional dyspepsia will be allocated into 3 groups： the low-He point group（puncturing at Zusanli（ST36））, Mu point group（puncturing at Zhongwan（CV12））, and He-Mu point combination group（puncturing at ST36 and CV12）. Every participant will receive 20 sessions of manual acupuncture for 4 weeks. The needles will be inserted perpendicularly to a depth of 1 to 2 cun. The angle of rotation and twisting will range from 90 to 180 degrees, while lifting and thrusting will range from 0.3 to 0.5 cm. The various manipulations will be performed 60 to 90 times per minute. The needles will remain in place for 30 minutes, during which manipulation will be applied every 10 minutes. Magnetic resonance imaging will be performed before and after 20 sessions of acupuncture. The primary outcome is symptom improvement according to the Chinese version of the Nepean Dyspepsia Index. Secondary outcomes include the Leeds dyspepsia questionnaire, Self-Rating Anxiety Scale, Self-Rating Depression Scale, Beck Anxiety Inventory, Beck Depression Inventory, and visual analogue scale scores before and after 10 and 20 sessions of acupuncture. Needle sensation and adverse events will be used to assess the therapeutic effects. This study will promote more widespread awareness of the benefits of acupoint combination in the clinical setting and provide a further explanation of the neuromechanism by which acupuncture at the He-Mu point combination for functional dyspepsia. Registration： Chinese Clinical Trial Registry, Chi CTR-IOR-15006402.展开更多
Objective:To clarify altered whole brain functional connectivity of the anterior cingulate cortex(ACC)in functional dyspepsia(FD)patients,and then to explore cerebral influence of acupuncture with deqi treating for FD...Objective:To clarify altered whole brain functional connectivity of the anterior cingulate cortex(ACC)in functional dyspepsia(FD)patients,and then to explore cerebral influence of acupuncture with deqi treating for FD.Methods:Thirty-two FD patients and 35 healthy subjects(HS)were firstly scanned by the resting-state blood oxygenation level-dependent functional magnetic resonance imaging(BOLD-fMRI)to compare differences of ACC-based functional connectivity(FC).Then 32 FD patients were randomized to receive 20 sessions’acupuncture treatment with(n=16)and without deqi(n=16),as well as underwent functional magnetic resonance imaging(fMRI)scans after treatment.After group re-division according to deqi response,changes of ACC subregions-based resting-state FC(rsFC)were compared between the actual with and without deqi group.Two seeds with bilateral of each were selected as regions of interest(ROIs)of the ACC,including two from the dorsal ACC:S2(BA24)(x=±5,y=2,z=46,r=3.5 mm)and two from the pregenual ACC:17(BA24)(x=±5,y=38,z=6,r=3.5 mm).The clinical changes of the Nepean Dyspepsia Index(NDI)that measuring symptoms and quality of life(QOL)were also used to further assess the correlation with ACC subregions rsFC in FD patients.Results:Compared to HS,FD patients showed significantly increased ACC subregions rsFC with left fusiform gyrus,temporal cortex,hippocampus(HIPP)/amygdala,temporal pole,and right INS,superior occipital gyrus,and bilateral precuneus,superior parietal lobule(SPL),and decreased rsFC with left postcentral/precentral gyrus(PoG/PrG),supplementary motor area(SMA)and right cerebellum.32 FD patients which were then re-divided into the actual deqi group(n=16)and actual without deqi group(n=16).The decrease of the NDI symptom score(pre-pos)in the actual deqi group was significantly greater than that in the actual without deqi group(P<0.05).Among the two groups,the actual deqi group showed increased ACC subregions rsFC with right SMA and bilateral PrG/PoG,and decreased rsFC with right precuneus,middle occipital gyrus,bilateral posterior cingulate cortex(PCC),HIPP/paraHIPP,angular gyrus and SPL after treatment.In addition,the changed NDI QOL scores(pre-post)of the actual deqi group was significantly positively correlated with their Fisher’s transformed Z value of the altered ACC subregion(left I7)rsFC with right SPL(r=-0.597,P=0.04<0.05,FDR corrected P>0.05).Conclusion:The results tested the hypothesis that the advantage of deqi on efficacy is related to affecting the ACC subregions rsFC.It suggested that deqi might participate in the adaptive modulation of disrupted relationship between the ACC subregions and the default mode network(DMN).展开更多
Background: The benefit of adjuvant chemotherapy for resectable cholangiocarcinoma remains unclear due to the lack of randomized control studies. This study aimed to investigate the possible benefit of postoperative a...Background: The benefit of adjuvant chemotherapy for resectable cholangiocarcinoma remains unclear due to the lack of randomized control studies. This study aimed to investigate the possible benefit of postoperative adjuvant chemotherapy for resectable cholangiocarcinoma. Data sources: Relevant research articles published before 1 st March 2018 in Pub Med, Embase and the Cochrane library databases were retrieved. Published data were extracted and analyzed by RevMan 5.3, and the results were presented as hazard ratios(HRs) [95% confidence intervals(CI)] and forest plots. Results: One prospective and eighteen retrospective studies were included, with a total number of 11,458 patients, 4696 of whom received postoperative chemotherapy. There was a significant improvement of the overall survival(OS) for patients who underwent operation + adjuvant chemotherapy compared to those who underwent operation alone(HR = 0.61; P < 0.001). Subgroup analyses show that the postoperative chemotherapy group compared with operation alone group are indicated as follows: hilar cholangiocarcinoma group(HR = 0.60; P < 0.001), intrahepatic cholangiocarcinoma group(HR = 0.60; P < 0.001), R1 resection group(HR = 0.71; P = 0.04), LN-positive diagnosis group(HR = 0.58; P < 0.001), gemcitabine-based chemotherapy group(HR = 0.42; P < 0.001), distal cholangiocarcinoma group(HR = 0.48; P = 0.17), R0 resection group(HR = 0.69; P = 0.43), and 5-flurouracil-based chemotherapy group(HR = 0.90; P = 0.66), respectively. Conclusions: Postoperative adjuvant chemotherapy can improve the OS in intrahepatic and hilar cholangiocarcinoma patients. However, distal cholangiocarcinoma patients gain no benefit from postoperative adjuvant chemotherapy. Prospective randomized trials are warranted in order to define the standard chemotherapy regimen.展开更多
In 2012,a lacquer figure was unearthed from the Han dynasty tomb(188 BC-87 BC) at Chengdu Laoguanshan.The lines intaglioed on the Laoguan mountain lacquer figure were similar to the meridians.Objective:To investigate ...In 2012,a lacquer figure was unearthed from the Han dynasty tomb(188 BC-87 BC) at Chengdu Laoguanshan.The lines intaglioed on the Laoguan mountain lacquer figure were similar to the meridians.Objective:To investigate the relationship between the lines on this Laoguanshan lacquer figure and the regular meridians so as to explore the development of meridian system in ancient China.Methods:Based on collecting the photos of the Laoguan mountain lacquer figure and the representative acupuncture classics,the double evidence method(combining the unearthed relics/literature and extant literature) was performed to investigate the relationship between the lines on this Laoguanshan lacquer figure and the regular meridians.Furthermore,the development of regular meridians theory was analyzed from the number,distribution,direction and branches.Results:The routes of the 28 longitudinal white lines on the Laoguan mountain lacquer figure are similar to the regular meridians in the ancient literature including Huángdì Nèijīng 《黄帝内经》 Yellow Emperor’s Inner Classic).The number,distribution and branches of the meridians intaglioed on the Laoguanshan lacquer figure suggested the evolution of the regular-meridian system from the eleven-meridian system to the twelve-meridian system.Conclusions:The meridian system of Laoguanshan lacquer figure was a link connecting the preceding and the following.The Laoguanshan lacquer figure played an important role in the development of the early meridian theory.展开更多
[Objective] The study aimed at evaluating the ability to save energy and reduce CO2 emission in China＇s cement industry. [Method] Based on long-term energy alternative planning system software （LEAP）, ＂LEAP of Ch...[Objective] The study aimed at evaluating the ability to save energy and reduce CO2 emission in China＇s cement industry. [Method] Based on long-term energy alternative planning system software （LEAP）, ＂LEAP of China＇s cement industry＂ model was established to simulate energy conservation and emission reduction in China＇s cement industry from 2010 to 2040 in different technologic situations. E ResultJ To save ener- gy and reduce CO2 emissions, new dry process kiln has priority over other technologies or measures, followed by equipment enlargement, mechani- cal shaft kiln, power generation system based on waste heat, as well as high-efficiency and energy-saving grinding technology, and new prepara- tion technology. If all the advanced technologies and measures are adopted, energy consumption and C02 emissions can be reduced by about 40.76% and 42.97% respectively. [ Condusion] LEAP of model is suitable for analyzing energy saving and emission reducing in China＇s cement industry and other industrial fields.展开更多
文摘The underground thermal fluid is one of the significant factors controlling the formation and quality of reservoirs.The Huangliu Formation(N_(1)h)in YF1 area of the central depression belt in the Yinggehai Basin,South China Sea,is characterized by intense thermal fluid activities related to mud diapir and large-scale shallow-water gravity flow deposits.The multi-episodic invasion of high-temperature and CO_(2)-rich thermal fluid into the formation induces complex water-rock reaction during diagenetic pro-cess,providing a preferable investigation opportunity for revealing how thermal fluid affects reservoir quality.This study characterizes the reservoirs in the formation through core and thin section analyses as well as physical property test.The reservoirs are dominated by fine-grained sandstone characterized by medium porosity(15.2-21.3%)and lower permeability(0.56-15.75mD).Based on an analysis of casting thin section,cathode luminescence(CL),scanning electron microscope(SEM),carbon and oxygen isotope,inclusion test,and electron-probe microanalysis(EPMA),we systematically investigate the diagenetic patterns and pore evolution process for the reservoirs in the formation.The episodic invasion of thermal fluid occurred approximately 0.4 Ma ago plays an important role in controlling reservoir development:The CO_(2)-rich formation water induces massive late-stage dissolution,resulting in a higher proportion of dissolved pores(38.7-46.4%),which improves the porosity of reservoirs at a depth of 2600-3100 m.Nevertheless,the late dissolution together with carbonate cementation occurred in closed diagenetic system blocks most seepage channels.Furthermore,the relatively high level clay mineral transformation in the YF1 area leads to a higher content of authigenic illite(44-62%)in the formation.Massive authigenic illite severely blocks the pore throats in fine sandstone,reducing permeability.This study offers an insight to the understanding of mud diapir-derived thermal fluid affecting and controlling the quality of reservoirs in some areas of the Yinggehai Basin.
基金supported by the National Natural Science Foundation of China(Grant Nos.12222515,12075324 for S.Yin,and 12347107,1257-4160 for Y.F.Jiang)the National Key R&D Program of China(Grant No.2022YFA1402703 for Y.F.Jiang)+1 种基金the Science and Technology Projects in Guangdong Province(Grant No.2021QN02X561 for S.Yin)the Science and Technology Projects in Guangzhou City(Grant No.2025A04J5408 for S.Yin)。
文摘The conventional Kibble–Zurek mechanism,describing driven dynamics across critical points based on the adiabatic-impulse scenario(AIS),has attracted broad attention.However,the driven dynamics at the tricritical point with two independent relevant directions have not been adequately studied.Here,we employ the time-dependent variational principle to study the driven critical dynamics at a one-dimensional supersymmetric Ising tricritical point.For the relevant direction along the Ising critical line,the AIS apparently breaks down.Nevertheless,we find that the critical dynamics can still be described by finite-time scaling in which the driving rate has a dimension of r_(μ)=z+1/v_(μ)with z and v_(μ)being the dynamic exponent and correlation length exponent in this direction,respectively.For driven dynamics along another direction,the driving rate has a dimension of r_(p)=z+1/v_(p)with v_(p)being another correlation length exponent.Our work brings a new fundamental perspective into nonequilibrium critical dynamics near the tricritical point,which could be realized in programmable quantum processors in Rydberg atomic systems.
基金supported by the Third Xinjiang Scientific Expedition Program(2022xjkk0903)the National Natural Science Foundation of China(42275145).
文摘Satellite observations are widely used to estimate the concentrations of surface air pollutants,but the temporal coverage of these datasets is relatively short.To overcome this limitation,we propose a wide-deep ensemble machine learning framework to reconstruct the fine particulate matter(particulate matter lower than 2.5 lm(PM_(2.5)))dataset of East Asia(EA)over the past four decades(1981-2020).The results indicate that the framework effectively leveraged the advantages of satellite observations(higher accuracy)and model-based estimations(longer temporal coverage)of surface air pollutants.The reconstructed PM_(2.5) concentrations agreed well with the ground measurements,with coefficient of determination(R^(2))and root-mean-square error(RMSE)values of 0.99 and 1.38 lg m^(3),respectively,which outperformed the satellite-based PM_(2.5) estimates.As more ground measurements were incorporated into the model for training,the average RMSE in Japan and the Korean Peninsula decreased to 0.83 and 1.50 lg m^(3),respectively.Simultaneously,on the basis of the reconstructed datasets,we investigated the exposure level to PM_(2.5) in EA from 1981 to 2020.Since 2000,the increase in anthropogenic emissions has substantially worsened the air quality in EA,and nearly 50% of the population resided in areas where the annual average PM_(2.5) concentrations exceeded 50 lg m^(3) from 2009 to 2010.Despite the implementation of various mitigation strategies by local authorities to lower the ambient PM_(2.5) concentrations,the entire exposure level in EA is still implausible to meet the World Health Organization(WHO)air quality guidelines.In addition,population aging and climate change have the potential to increase PM_(2.5) exposure risk in the future.For policy-makers in EA,it is essential to consider the effects of these factors and develop more effective mitigation strategies that aim to lessen the health impact associated with PM_(2.5) exposure.
基金supported by the Key R&D Plan of Shaanxi Province[key industrial innovation chain(Group)](No.2022ZDLSF07-04).
文摘The third member of Shahejie Formation(also referred to as Sha 3 Member)in Dongpu Depression,China,a volatile,low-permeability oil reservoir with complex fluid compositions,is subjected to high temperature and high pressure(HPHT),which poses significant challenges to conventional water injection.To elucidate flow mechanisms and optimize development strategies,this study integrates constant-rate mercury injection(CRMI),nuclear magnetic resonance(NMR),and HPHT three-phase oil/gas/water relative permeability experiments to analyze pore-throat structures,movable fluid characteristics,and relative permeability.The CRMI results indicate that the reservoir exhibits low porosity and low permeability,with dominant throat radius ranging from 0.6 to 5.0μm,and mean pore-throat radius ratio ranging from 40.303 to 278.320,demonstrating significant microscopic heterogeneity.The NMR results reveal that water-alternating-gas(WAG)injection enhances oil recovery by 16.28%(Sample W1)and 13.52%(Sample W2)compared to conventional water injection,primarily due to the gas phase's low viscosity and high mobility,enabling access to micropores unreachable by water phases.The HPHT three-phase relative permeability tests demonstrate positive correlations between saturation and relative permeability,with oil permeability significantly influenced by three-phase saturation and rock wettability.These findings establish a microscopic seepage model for optimizing enhanced oil recovery(EOR)strategies in volatile reservoirs.
基金supported by the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.SJCX23_0120)the National Natural Science Foundation of China(Nos.22275088 and 52101260)+3 种基金the Project of Shuangchuang Scholar of Jiangsu Province(No.JSSCBS20210212)the Fundamental Research Funds for the Central Universities(No.30921011203)the Start-Up Grant(No.AE89991/340)from Nanjing University of Science and Technology,the Foundation of Jiangsu Educational Committee(No.22KJB310008)the Senior Talent Program of Jiangsu University(No.20JDG073).
文摘The reduction of global carbon emissions and the achievement of carbon neutrality have become the focus of addressing climate change and global warming.Electrochemical CO_(2) reduction(CO_(2)RR),as a technology that can efficiently convert CO_(2) into value-added products,is receiving widespread attention.This article reviews the current research status of Cu/metal oxide heterostructures in the field of electrochemical reduction of CO_(2).The review first introduces the importance of electrochemical reduction of CO_(2) and the application potential of Cu/metal oxide heterostructures in this field.Subsequently,a comprehensive discussion is presented on the exploration of various Cu/metal oxide heterostructures and their corresponding structure-performance relationship,with particular emphasis on the catalysts'activity,selectivity,stability and the nature of active sites.Lastly,the review provides an overview of the current research challenges and future development trends in this field.
基金supported by the National Natural Science Foundation of China(Grant Nos.12104109,12222515,and 12075324)the Science and Technology Projects in Guangzhou(Grant No.2024A04J2092)the Science and Technology Projects in Guangdong Province(Grant No.211193863020).
文摘Driven critical dynamics in quantum phase transitions holds significant theoretical importance,and also has practical applications in fast-developing quantum devices.While scaling corrections have been shown to play important roles in fully characterizing equilibrium quantum criticality,their impact on nonequilibrium critical dynamics has not been extensively explored.In this work,we investigate the driven critical dynamics in a two-dimensional quantum Heisenberg model.We find that in this model the scaling corrections arising from both finite system size and finite driving rate must be incorporated into the finite-time scaling form in order to properly describe the nonequilibrium scaling behaviors.In addition,improved scaling relations are obtained from the expansion of the full scaling form.We numerically verify these scaling forms and improved scaling relations for different starting states using the nonequilibrium quantum Monte Carlo algorithm.
基金supported by the National Scientific Foundation Committee in China,No.81473602the Education Ministry’s New Century Excellent Talents Supporting Plan in China+3 种基金the Foundation for the Author of National Excellent Doctoral Dissertation of China,No.201486the Youth Foundation of Science and Technology Department of Sichuan Province in China,No.15QNJJ0008the National Natural Science Foundation-Excellent Youth Foundation in China,No.81622052the 2011 Co-Innovation Center of Sichuan Province named Acupoint Effects of Acupuncture Co-Innovation Center
文摘Acupuncture is widely used to treat functional dyspepsia with satisfactory outcomes. Combination of the He and Mu acupoints is commonly used and has a synergistic effect on functional dyspepsia; however, its underlying mechanisms remain unclear. Therefore, a randomized controlled parallel clinical trial is currently underway at Chengdu University of Traditional Chinese Medicine, China. This trial is designed to explore the efficacy of and central responses to the He-Mu point combination in patients with functional dyspepsia using functional magnetic resonance imaging. A total of 105 patients with functional dyspepsia will be allocated into 3 groups： the low-He point group（puncturing at Zusanli（ST36））, Mu point group（puncturing at Zhongwan（CV12））, and He-Mu point combination group（puncturing at ST36 and CV12）. Every participant will receive 20 sessions of manual acupuncture for 4 weeks. The needles will be inserted perpendicularly to a depth of 1 to 2 cun. The angle of rotation and twisting will range from 90 to 180 degrees, while lifting and thrusting will range from 0.3 to 0.5 cm. The various manipulations will be performed 60 to 90 times per minute. The needles will remain in place for 30 minutes, during which manipulation will be applied every 10 minutes. Magnetic resonance imaging will be performed before and after 20 sessions of acupuncture. The primary outcome is symptom improvement according to the Chinese version of the Nepean Dyspepsia Index. Secondary outcomes include the Leeds dyspepsia questionnaire, Self-Rating Anxiety Scale, Self-Rating Depression Scale, Beck Anxiety Inventory, Beck Depression Inventory, and visual analogue scale scores before and after 10 and 20 sessions of acupuncture. Needle sensation and adverse events will be used to assess the therapeutic effects. This study will promote more widespread awareness of the benefits of acupoint combination in the clinical setting and provide a further explanation of the neuromechanism by which acupuncture at the He-Mu point combination for functional dyspepsia. Registration： Chinese Clinical Trial Registry, Chi CTR-IOR-15006402.
基金grants from the National Natural Science Foundation of Outstanding Youth Fund in China:81622052National Natural Science Foundation of China:81473602+2 种基金the major program of the National Natural Science Foundation of China:81590950the Ten Thousand Talent Program:W02020595Youth Science and Technology Innovative Team of Sichuan Province:2019JDTD0011。
文摘Objective:To clarify altered whole brain functional connectivity of the anterior cingulate cortex(ACC)in functional dyspepsia(FD)patients,and then to explore cerebral influence of acupuncture with deqi treating for FD.Methods:Thirty-two FD patients and 35 healthy subjects(HS)were firstly scanned by the resting-state blood oxygenation level-dependent functional magnetic resonance imaging(BOLD-fMRI)to compare differences of ACC-based functional connectivity(FC).Then 32 FD patients were randomized to receive 20 sessions’acupuncture treatment with(n=16)and without deqi(n=16),as well as underwent functional magnetic resonance imaging(fMRI)scans after treatment.After group re-division according to deqi response,changes of ACC subregions-based resting-state FC(rsFC)were compared between the actual with and without deqi group.Two seeds with bilateral of each were selected as regions of interest(ROIs)of the ACC,including two from the dorsal ACC:S2(BA24)(x=±5,y=2,z=46,r=3.5 mm)and two from the pregenual ACC:17(BA24)(x=±5,y=38,z=6,r=3.5 mm).The clinical changes of the Nepean Dyspepsia Index(NDI)that measuring symptoms and quality of life(QOL)were also used to further assess the correlation with ACC subregions rsFC in FD patients.Results:Compared to HS,FD patients showed significantly increased ACC subregions rsFC with left fusiform gyrus,temporal cortex,hippocampus(HIPP)/amygdala,temporal pole,and right INS,superior occipital gyrus,and bilateral precuneus,superior parietal lobule(SPL),and decreased rsFC with left postcentral/precentral gyrus(PoG/PrG),supplementary motor area(SMA)and right cerebellum.32 FD patients which were then re-divided into the actual deqi group(n=16)and actual without deqi group(n=16).The decrease of the NDI symptom score(pre-pos)in the actual deqi group was significantly greater than that in the actual without deqi group(P<0.05).Among the two groups,the actual deqi group showed increased ACC subregions rsFC with right SMA and bilateral PrG/PoG,and decreased rsFC with right precuneus,middle occipital gyrus,bilateral posterior cingulate cortex(PCC),HIPP/paraHIPP,angular gyrus and SPL after treatment.In addition,the changed NDI QOL scores(pre-post)of the actual deqi group was significantly positively correlated with their Fisher’s transformed Z value of the altered ACC subregion(left I7)rsFC with right SPL(r=-0.597,P=0.04<0.05,FDR corrected P>0.05).Conclusion:The results tested the hypothesis that the advantage of deqi on efficacy is related to affecting the ACC subregions rsFC.It suggested that deqi might participate in the adaptive modulation of disrupted relationship between the ACC subregions and the default mode network(DMN).
基金supported by a grant from the Natural Science Foundation of Anhui Province,China(1408085MKL70)
文摘Background: The benefit of adjuvant chemotherapy for resectable cholangiocarcinoma remains unclear due to the lack of randomized control studies. This study aimed to investigate the possible benefit of postoperative adjuvant chemotherapy for resectable cholangiocarcinoma. Data sources: Relevant research articles published before 1 st March 2018 in Pub Med, Embase and the Cochrane library databases were retrieved. Published data were extracted and analyzed by RevMan 5.3, and the results were presented as hazard ratios(HRs) [95% confidence intervals(CI)] and forest plots. Results: One prospective and eighteen retrospective studies were included, with a total number of 11,458 patients, 4696 of whom received postoperative chemotherapy. There was a significant improvement of the overall survival(OS) for patients who underwent operation + adjuvant chemotherapy compared to those who underwent operation alone(HR = 0.61; P < 0.001). Subgroup analyses show that the postoperative chemotherapy group compared with operation alone group are indicated as follows: hilar cholangiocarcinoma group(HR = 0.60; P < 0.001), intrahepatic cholangiocarcinoma group(HR = 0.60; P < 0.001), R1 resection group(HR = 0.71; P = 0.04), LN-positive diagnosis group(HR = 0.58; P < 0.001), gemcitabine-based chemotherapy group(HR = 0.42; P < 0.001), distal cholangiocarcinoma group(HR = 0.48; P = 0.17), R0 resection group(HR = 0.69; P = 0.43), and 5-flurouracil-based chemotherapy group(HR = 0.90; P = 0.66), respectively. Conclusions: Postoperative adjuvant chemotherapy can improve the OS in intrahepatic and hilar cholangiocarcinoma patients. However, distal cholangiocarcinoma patients gain no benefit from postoperative adjuvant chemotherapy. Prospective randomized trials are warranted in order to define the standard chemotherapy regimen.
基金Supported by the Youth Project of National Social Science Fund of China:14CKG008the Project of Chengdu Science and Technology:2014-RK00-00078-ZFthe Project of Sichuan Provincial Administration of Traditional Chinese Medicine:2014K091。
文摘In 2012,a lacquer figure was unearthed from the Han dynasty tomb(188 BC-87 BC) at Chengdu Laoguanshan.The lines intaglioed on the Laoguan mountain lacquer figure were similar to the meridians.Objective:To investigate the relationship between the lines on this Laoguanshan lacquer figure and the regular meridians so as to explore the development of meridian system in ancient China.Methods:Based on collecting the photos of the Laoguan mountain lacquer figure and the representative acupuncture classics,the double evidence method(combining the unearthed relics/literature and extant literature) was performed to investigate the relationship between the lines on this Laoguanshan lacquer figure and the regular meridians.Furthermore,the development of regular meridians theory was analyzed from the number,distribution,direction and branches.Results:The routes of the 28 longitudinal white lines on the Laoguan mountain lacquer figure are similar to the regular meridians in the ancient literature including Huángdì Nèijīng 《黄帝内经》 Yellow Emperor’s Inner Classic).The number,distribution and branches of the meridians intaglioed on the Laoguanshan lacquer figure suggested the evolution of the regular-meridian system from the eleven-meridian system to the twelve-meridian system.Conclusions:The meridian system of Laoguanshan lacquer figure was a link connecting the preceding and the following.The Laoguanshan lacquer figure played an important role in the development of the early meridian theory.
基金Supported by Special Project for Developing National Major Scientific Instruments and Equipments (2011YQ060111)Scientific Research Project of Environmental Protection in Commonweal Industry(201009032)
文摘[Objective] The study aimed at evaluating the ability to save energy and reduce CO2 emission in China＇s cement industry. [Method] Based on long-term energy alternative planning system software （LEAP）, ＂LEAP of China＇s cement industry＂ model was established to simulate energy conservation and emission reduction in China＇s cement industry from 2010 to 2040 in different technologic situations. E ResultJ To save ener- gy and reduce CO2 emissions, new dry process kiln has priority over other technologies or measures, followed by equipment enlargement, mechani- cal shaft kiln, power generation system based on waste heat, as well as high-efficiency and energy-saving grinding technology, and new prepara- tion technology. If all the advanced technologies and measures are adopted, energy consumption and C02 emissions can be reduced by about 40.76% and 42.97% respectively. [ Condusion] LEAP of model is suitable for analyzing energy saving and emission reducing in China＇s cement industry and other industrial fields.
