Based on the preferential continuation method proposed by Pawlowski （1995）, we propose a method and procedure for gravity anomaly separation with the preferential upward continuation operator in the case that the va...Based on the preferential continuation method proposed by Pawlowski （1995）, we propose a method and procedure for gravity anomaly separation with the preferential upward continuation operator in the case that the various sources are uncorrelated with one another and the continuation height is enough large. We also present a method for estimating optimum upward-continuation height, based on analyzing the characteristics of the preferential upward continuation operators of a synthesized gravity anomaly varying with different continuation heights. The method is tested on the raw Bouguer gravity data over an iron deposit. The result shows that the method separates the data into regional anomaly and residual anomaly efficiently and clearly.展开更多
目的探讨辅助性T细胞17(helper T cell 17,Th17)/调节性T细胞(regulatory T cell,Treg)水平在肾移植患者中的表达及其对肺部感染发生的预测价值。方法回顾性分析2020年1月至2022年12月新疆维吾尔自治区人民医院74例肾移植患者的临床资...目的探讨辅助性T细胞17(helper T cell 17,Th17)/调节性T细胞(regulatory T cell,Treg)水平在肾移植患者中的表达及其对肺部感染发生的预测价值。方法回顾性分析2020年1月至2022年12月新疆维吾尔自治区人民医院74例肾移植患者的临床资料。患者于术前、术后2个月时检测外周血Th17、Treg细胞比例,计算Th17/Treg水平。患者术后完成1年随访,依据患者术后肺部感染情况分为感染组、非感染组。重点观察Th17/Treg细胞在肾移植患者中的表达,并分析Th17/Treg对肾移植患者术后肺部感染的预测价值。结果有无吸烟史、糖尿病、低蛋白血症、肺部感染史的肾移植患者术前Th17/Treg水平比较,差异有统计学意义(P<0.05)。74例肾移植患者随访期间并发肺部感染21例,发生率为28.38%(21/74)。感染组有吸烟史、糖尿病、低蛋白血症、肺部感染史占比高于非感染组,术后2个月他克莫司血药浓度高于非感染组;术前、术后外周血Treg细胞比例均低于非感染组,Th17细胞比例、Th17/Treg水平均高于非感染组(P<0.05)。绘制操作者工作特征(receiver operating characteristic,ROC)曲线结果显示,术前、术后2个月时Th17、Treg细胞比例、Th17/Treg水平预测肾移植患者术后并发肺部感染的AUC值均≥0.7,均有一定预测价值,其中术前Th17/Treg水平预测价值更理想。结论肾移植患者Th17/Treg水平升高可能参与肾移植患者术后肺部感染发生过程,且高表达者多存在吸烟史、合并糖尿病等发生肺部感染的危险因素,术前检查患者Th17/Treg水平可有效预测术后并发肺部感染风险。展开更多
基金supported jointly by projects of the 863 Program (Grant Nos.2006AA06Z111,2006AA06A201-3,and 20060109A1002-0201-03)
文摘Based on the preferential continuation method proposed by Pawlowski （1995）, we propose a method and procedure for gravity anomaly separation with the preferential upward continuation operator in the case that the various sources are uncorrelated with one another and the continuation height is enough large. We also present a method for estimating optimum upward-continuation height, based on analyzing the characteristics of the preferential upward continuation operators of a synthesized gravity anomaly varying with different continuation heights. The method is tested on the raw Bouguer gravity data over an iron deposit. The result shows that the method separates the data into regional anomaly and residual anomaly efficiently and clearly.
文摘目的探讨辅助性T细胞17(helper T cell 17,Th17)/调节性T细胞(regulatory T cell,Treg)水平在肾移植患者中的表达及其对肺部感染发生的预测价值。方法回顾性分析2020年1月至2022年12月新疆维吾尔自治区人民医院74例肾移植患者的临床资料。患者于术前、术后2个月时检测外周血Th17、Treg细胞比例,计算Th17/Treg水平。患者术后完成1年随访,依据患者术后肺部感染情况分为感染组、非感染组。重点观察Th17/Treg细胞在肾移植患者中的表达,并分析Th17/Treg对肾移植患者术后肺部感染的预测价值。结果有无吸烟史、糖尿病、低蛋白血症、肺部感染史的肾移植患者术前Th17/Treg水平比较,差异有统计学意义(P<0.05)。74例肾移植患者随访期间并发肺部感染21例,发生率为28.38%(21/74)。感染组有吸烟史、糖尿病、低蛋白血症、肺部感染史占比高于非感染组,术后2个月他克莫司血药浓度高于非感染组;术前、术后外周血Treg细胞比例均低于非感染组,Th17细胞比例、Th17/Treg水平均高于非感染组(P<0.05)。绘制操作者工作特征(receiver operating characteristic,ROC)曲线结果显示,术前、术后2个月时Th17、Treg细胞比例、Th17/Treg水平预测肾移植患者术后并发肺部感染的AUC值均≥0.7,均有一定预测价值,其中术前Th17/Treg水平预测价值更理想。结论肾移植患者Th17/Treg水平升高可能参与肾移植患者术后肺部感染发生过程,且高表达者多存在吸烟史、合并糖尿病等发生肺部感染的危险因素,术前检查患者Th17/Treg水平可有效预测术后并发肺部感染风险。
