This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on ...This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on postoperative quality of life and recovery in Arabic-speaking patients with traumatic foot and ankle injuries.In the context of systemic linguistic exclusion in orthopedic research—where English-language journals dominated most publi-cations and non-English-speaking populations faced dual barriers of trial under-representation and semantic distortions(e.g.,mistranslations of terms like"joint instability"in Arabic)—AlMousa et al's work highlighted the transformative po-tential of culturally adapted methodologies.Their rigorous four-stage adaptation framework validated the Arabic AAOS-FAOQ as a reliable tool,enhancing ecological validity and reducing bias in patient-reported outcomes.However,limitations such as regional specificity(Gulf-centric sampling)and short follow-up periods(4 months)underscored broader challenges in non-English research:Redundant studies,prolonged hospital stays for limited English proficiency patients,and underrepresentation of certain ethnic groups in trials.To dismantle linguistic hegemony,we proposed semantic reconstruction(e.g.,integrating culturally specific indicators like"prayer posture"),dialect-aware neural tran-slation,and World Health Organization led terminology standardization.In line with these proposed solutions,AlMousa et al’s study exemplified how language-sensitive adaptations could bridge equity gaps,while future efforts would need to balance cultural specificity with cross-study comparability through AI-driven multilingual databases and policy mandates for cultural adaptation roadmaps.展开更多
The effects of yam powder(YP)on the functional properties of wheat flour noodles were investigated to improve the nutritional value of noodles and provide a scientific basis for YP application in flour products.Using ...The effects of yam powder(YP)on the functional properties of wheat flour noodles were investigated to improve the nutritional value of noodles and provide a scientific basis for YP application in flour products.Using wheat flour as the main ingredient,the effects of different YP substitution ratios(0,5%,10%,15%,20%,and 25%)on polyphenolic content,2,2-diphenyl-1-picrylhydrazyl(DPPH)free radical scavenging rate,and starch digestibility of the prepared noodles were analyzed in vitro.Additionally,the effects of YP water-soluble extracts,wheat flour noodles,and YP-enriched noodles(hereinafter,YP noodles)on inflammatory factors in vascular smooth muscle cells(VSMCs)treated by H_(2)O_(2)(100μM)were investigated.The results showed that YP had a substantial effect on polyphenolic content and DPPH free radical scavenging rate of wheat flour noodles,significantly increasing both values compared with those of the control group(P<0.05).The polyphenolic content reached a maximum of 2.17 mg/g in noodles with 20%YP substitution,whereas DPPH free radical scavenging rate reached a maximum of 42.10%in noodles with 25%YP substitution.With an increase in YP amount,both starch hydrolysis rate and rapidly digestible starch content of the noodles decreased gradually,whereas resistant starch content increased significantly.Moreover,50,100,and 200μg/mL of water-soluble YP and YP noodle extracts had no significant effect on the viability of VSMCs,and high concentrations of YP and YP noodle extracts resulted in cell death.Both YP and noodle extracts also reduced the secretion levels of inflammatory factors IL-6 and TNF-α in H_(2)O_(2)-treated VSMCs.Overall,YP addition reduced starch digestibility,increased antioxidative activity,and effectively improved functional quality of noodles.This study provides reference for the research and development of health-benefiting anti-inflammatory foods.展开更多
BACKGROUND Bipolar disorder(BD),marked by recurring manic and depressive episodes,often coexists with anxiety disorder(AD),which increases treatment complexity and morbidity.Although quetiapine,an atypical antipsychot...BACKGROUND Bipolar disorder(BD),marked by recurring manic and depressive episodes,often coexists with anxiety disorder(AD),which increases treatment complexity and morbidity.Although quetiapine,an atypical antipsychotic,has demonstrated efficacy in treating BD and AD,further investigation is needed regarding its effectiveness and safety in patients with AD at high-risk factors for BD.AIM To explore the application and efficacy of quetiapine in combination therapy for patients with AD at high-risk factors for BD.METHODS This study included 67 patients,with two excluded,leaving 65 divided into Group A(sertraline treatment)and Group B(combination treatment).All patients received sertraline,with Group B additionally receiving quetiapine.Efficacy was assessed using the Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD),and Bech-Rafaelsen Mania sale(BRMS)throughout the treatment period.Side effects and physiological indicators were also monitored.RESULTS No significant baseline differences existed between the two groups at treatment onset.Over the treatment course,Group B exhibited significantly lower HAMA scores than Group A at the end of weeks 1 and 24.HAMD scores gradually decreased over time,with Group B consistently showing lower scores than Group A.BRMS scores decreased significantly from baseline by week 8.In Group A,27.27%of patients received zolpidem treatment compared to 10.53%in Group B,which was a significant difference.Incidence of adverse reactions did not differ significantly between groups at treatment onset,but most patients experienced relief from adverse reactions within 4 weeks.CONCLUSION Combination of quetiapine and sertraline can more rapidly alleviate anxiety and depressive symptoms in patients with AD at high-risk factors for BD,improving treatment outcomes.展开更多
This editorial critically evaluated Liu et al's recent retrospective analysis of 283 Chinese patients with resectable pancreatic ductal adenocarcinoma(PDAC)that validated a preoperative computed tomography-based r...This editorial critically evaluated Liu et al's recent retrospective analysis of 283 Chinese patients with resectable pancreatic ductal adenocarcinoma(PDAC)that validated a preoperative computed tomography-based risk scoring system origi-nally developed in South Korea.The scoring system incorporated five parame-ters:(1)Tumor size;(2)Portal venous phase density;(3)Necrosis;(4)Peripan-creatic infiltration;and(5)Suspected metastatic lymph nodes.While demonstra-ting satisfactory recurrence prediction capability without requiring complex tech-nologies,thereby supporting clinical utility in Chinese populations,the study exhibited notable limitations.Most analyzed patients lacked neoadjuvant chemo-therapy exposure,resulting in underrepresentation of low-risk subgroups.Addi-tionally,the short follow-up duration potentially compromised long-term progno-stic assessment.Contemporary advances in radiomics coupled with machine learning have enhanced multimodal data integration for PDAC management.However,clinical implementation continues to confront challenges including variability in imaging parameters,incomplete understanding of molecular underpinnings,and confounding treatment effects.Future investigations should prioritize developing multidimensional predictive frameworks that synergize radiographic,molecular,and clinical data.Prospective multicenter validation and artificial intelligence-powered real-time risk stratification systems represent essential steps to overcome current barriers in precision medicine translation,ultimately advancing personalized therapeutic strategies for PDAC.展开更多
Electroplating sludge(ES),a byproduct of the electroplating industry,is a significant environmental concern due to its high content of soluble heavy metals(HMs).The significance of spinel formation from ES lies in its...Electroplating sludge(ES),a byproduct of the electroplating industry,is a significant environmental concern due to its high content of soluble heavy metals(HMs).The significance of spinel formation from ES lies in its potential for HMs enrichment and environmental remediation,offering a sustainable solution for hazardous waste management.The article delves into themultifaceted recycling of HMs-rich spinel fromES,encompassing its synthesis,metal enrichment,and thermodynamic stability.The pyro-metallurgical and hydrometallurgical processes for spinel synthesis were discussed,with a focus on the critical role of thermodynamic data in predicting the stability and formation of spinel structures.The crystallographic and magnetic properties of spinels,with their applications in environmental remediation and energy storage are highlighted.The article provides a comprehensive reviewon the recycling of HMs-rich spinel fromES,offering a means to recycle HMs,mitigate ecological harm,and contribute to a circular economy through the recovery and application of valuable materials.The selective leaching of metals from ES also faces challenges,which was limited by the separation,purification steps and high energy consumption.This high energy consumption is a significant operational cost and also contributes to environmental concerns related to carbon emissions.It is essential to address the challenges through continued research and development,improved technologies,and supportive regulatory frameworks.展开更多
This editorial critically evaluated the recent study by Wang et al,which systematically investigated the efficacy of perioperative disinfection and isolation measures(including preoperative povidone-iodine disinfectio...This editorial critically evaluated the recent study by Wang et al,which systematically investigated the efficacy of perioperative disinfection and isolation measures(including preoperative povidone-iodine disinfection,intraoperative sterile barrier techniques,and postoperative intensive care)in reducing infection rates.The study further incorporated the surgical site infection risk prediction model(constructed via the least absolute shrinkage and selection operator al-gorithm,integrating patients'baseline characteristics,surgical indicators,and regional antibiotic-resistant bacterial data),and proposed a dynamic prevention and control system termed“disinfection protocols-predictive models–real-time monitoring”.The article highlighted that preoperative risk stratification,intraoperative personalized antibiotic selection,and postoperative multidimensional monitoring(encompassing inflammatory biomarkers,imaging,and microbiological testing)enabled the precise identification of high-risk patients and optimized intervention thresholds.Future research is deemed necessary to validate the synergistic effects of disinfection protocols and predictive models through large-scale multicenter studies,combined with advanced intraoperative rapid microbial detection technologies.This approach aims to establish standardized infection control protocols tailored for precision medicine and regional adaptability.Future research should prioritize validating the synergistic effects of disinfection protocols and predictive models via multi-center studies,while incorporating advanced rapid intraoperative microbial detection technologies to develop standardized infection prevention and control procedures.Such efforts will enhance the implementation of precise and regionally adaptive infection control strategies.展开更多
In this study,3,4-Epoxycyclohexylmethyl 3,4-epoxycyclohexanecarboxylate(ECC)and refined Camellia oleifera seed oil(RCOSO)obtained from saponification and acidified hydrolysis has been used as raw materials to perform ...In this study,3,4-Epoxycyclohexylmethyl 3,4-epoxycyclohexanecarboxylate(ECC)and refined Camellia oleifera seed oil(RCOSO)obtained from saponification and acidified hydrolysis has been used as raw materials to perform ring-opening reactions for the preparation of cyclohexyl acrylate derivative(CAR).The structure of the synthesized product was characterized using infrared spectroscopy,Raman spectroscopy,and nuclear magnetic resonance spectroscopy.CAR was employed as a plasticizer to produce modified polyvinyl chloride(PVC)films,dioctyl phthalate plasticizer(DOP)used in reference samples to investigate the influence of different plasticizer molecular structures on the properties of PVC films.Observation suggested that(1)CAR plasticizer was successfully synthesized;(2)CAR can interact with PVC,exhibiting good compatibility;(3)PVC films contain CAR showed improved thermal stability,hydrophilicity,and tensile strength.Therefore,CAR has the potential to replace DOP as a plasticizer for PVC.展开更多
AIM： To provide the expression profile of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 （HAI-1） in normal and malignant tissues of gastrointestinal tract at ...AIM： To provide the expression profile of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 （HAI-1） in normal and malignant tissues of gastrointestinal tract at mRNA level for further study on their correlations with tumor progression and metastasis. METHODS： Total RNAs were prepared from 37 samples of colorectal cancer tissues, 40 samples of gastric cancer tissues, and their adjacent normal tissues. The expression of SNC19/matriptase and HAI-1 in these samples was detected by real-time fluorescent quantitative PCR using glyceraldehyde-3-phosphate dehydrogenase as internal standard, and the clinical significance for the correlation with clinicopathological parameters was evaluated. RESULTS： In gastric cancer tissues the expression of HAI-1 and SNC19/matriptase was significantly lower than that in the corresponding adjacent normal tissues （Z = -3.280, P= 0.006; Z= -4.651, P= 0.000）. HAI-1：SNC19/matriptase ratio showed no difference between normal and malignant tissues （P〉0.05）. Analysis of clinicopathological parameters showed decreased expression of HAI-1 and HAI-1：SNC19/ matriptase ratio associated with stage Ⅲ/Ⅳ gastric tumors as compared to stage Ⅰ/Ⅱ ones （Z= -2.140, P= 0.031; Z = -2.155, P = 0.031）, and with lymph node-positive gastric cancer tissues as compared to lymph node-negative ones （Z = -2.081, P = 0.036; Z= -2.686, P = 0.006）. The expression of SNC19/matriptase had no relationship with stages and lymph node metastasis （P〉0.05）. The expression of HAI-1 and HAI-1：SNC19/matriptase ratio increased in well-differentiated gastric cancer tissues, but there was no statistical significance （P〉0.05）. The difference of SNC19/matriptase expression was not significant in gastric cancer tissues of different histological differentiation status （P〉0.05）. In colorectal cancer tissues, the expression of HAI-1 and SNC19/matriptase was also markedly lower than that in their adjacent normal tissues （Z= -3.100, P = 0.002; Z= -2.731, P = 0.006）, whereas HAI-1：SNC19/matriptase ratio showed no difference. Decreased expression of HAI-1 was associated with increased invasive depth and lymph node metastasis, but there was no statistical significance （P〉0.05）. The difference of SNC19/matriptase expression and HAI-1： SNC19/matriptase ratio was not significant in different stages and different lymph node metastasis status （P〉0.05）. The expression of SNC19/matriptase, HAI-1 or HAI-1： SNC19/matriptase ratio showed no difference in colorectal cancer tissues of different histological differentiation status （P〉0.05）. CONCLUSION： The expressions of SNC19/matriptase and its inhibitor HAI-1 are decreased in gastrointestinal cancer tissues compared to their normal counterparts, and the decreased expression of HAI-1 may correlate with invasion and lymph node metastasis. The possible mechanisms involved need to be further investigated.展开更多
To improve the safety and driving stability of the autonomous heavy truck, it is necessary to consider the differences of driving behavior and drivable trajectories between the heavy trucks and passenger cars. This st...To improve the safety and driving stability of the autonomous heavy truck, it is necessary to consider the differences of driving behavior and drivable trajectories between the heavy trucks and passenger cars. This study proposes a probabilistic decision-making and trajectory planning framework for the autonomous heavy trucks. Firstly, the driving decision process is divided into intention generation and feasibility evaluations, which are realized using the utility theory and risk assessment, respectively. Subsequently the driving decision is made and sent to the trajectory planning module. In order to reflect the greater risks of the truck to other surrounding vehicles, the aggressiveness index(AI) is proposed and quantified to infer the asymmetrical risk level of lane-change maneuver. In the planning stage, the lateral and roll dynamics stability domains are developed as the constraints to exclude the candidate trajectories that would cause vehicle instability. Finally, the simulation results are compared between the proposed model and the artificial potential filed model in the scenarios extracted from the naturalistic driving data. It is shown that the proposed framework can provide the human-like lane-change decisions and truck-friendly trajectories, and performs well in dynamic driving environments.展开更多
At present,investigation about the relationship between the change of groundwater level and vegetation mostly focuses on specific watersheds,i.e.limited in river catchment scale.Understanding the change of groundwater...At present,investigation about the relationship between the change of groundwater level and vegetation mostly focuses on specific watersheds,i.e.limited in river catchment scale.Understanding the change of groundwater level on vegetation in the basin or large scale,be urgently needed.To fill this gap,two typical arid areas in the west of China(Tarim Basin and Qaidam Basin)were chosen the a typical research area.The vegetation status was evaluated via normalization difference vegetation index(NDVI)from 2000 to 2016,sourced from MODN1F dataset.The data used to reflect climate change were download from CMDSC(http://data.cma.cn).Groundwater level data was collected from monitor wells.Then,the relationship of vegetation and climate change was established with univariate linear regression and correlation analysis approach.Results show that:Generally,NDVI value in the study area decreased before 2004 then increased in the research period.Severe degradation was observed in the center of the basin.The area with an NDVI value>0.5 decreased from 12%to 6%between 2000 and 2004.From 2004 to 2014,the vegetation in the study area was gradually restored.The whole coverage of Qaidam Basin was low.And the NDVI around East Taigener salt-lake degraded significantly,from 0.596 to 0.005,2014 and 2016,respectively.The fluctuation of groundwater level is the main reason for the change of surface vegetation coverage during the vegetation degradation in the basin.However,the average annual precipitation in the study area is low,which is not enough to have a significant impact on vegetation growth.The annual average precipitation showed an increase trend during the vegetation restoration in the basin,which alleviates the water shortage of vegetation growth in the region.Meanwhile,the dependence of surface vegetation on groundwater is obviously weakened with the correlation index is−0.248.The research results are of some significance to eco-environment protection in the arid area of western China.展开更多
It is a prospective strategy to produce sustainable energy by photocatalytic overall water splitting(POWS).This work aims to develop a simple method for integrating a donor-acceptor system into polymeric car-bon nitri...It is a prospective strategy to produce sustainable energy by photocatalytic overall water splitting(POWS).This work aims to develop a simple method for integrating a donor-acceptor system into polymeric car-bon nitride(PCN)structure,which could accelerate the charge separation significantly.In the as-prepared photocatalyst(COCNT),carbon and oxygen were successfully incorporated into the framework of PCN,and the chemical environment of C and O was well probed by X-ray absorption near-edge structure(XANES)and X-ray photoelectron spectroscopy(XPS).It showed that the C-containing and O-containing segments of COCNT played the role of a donor,while the heptazine part played the role of an acceptor.In addition,Density-functional-theory(DFT)calculations confirmed the spatial split of the highest occupied molec-ular orbital(HOMO)and lowest unoccupied molecular orbital(LUMO)for promoting charge separation.Impressively,COCNT could efficiently split pure water to generate hydrogen and oxygen.And,the photo-catalytic hydrogen evolution rate over COCNT(1550.9μmol g^(-1)h^(-1))is about 17-fold higher than that of PCN.Finally,we proposed a possible photocatalytic mechanism to explain the above results.展开更多
The random mobility of charge carriers is a main factor causing the low photocatalytic efficiency of gCN.Thus,the controllable migration of charge carriers is a rational strategy to suppress the charge recombination a...The random mobility of charge carriers is a main factor causing the low photocatalytic efficiency of gCN.Thus,the controllable migration of charge carriers is a rational strategy to suppress the charge recombination and facilitate charge separation.Herein,an ethylenediamine modified g-C_(3)N_(4)displays improved photocatalytic activity.The excellent charge separation efficiency is confirmed to be a key factor for the enhancement.The TEM observation after photo-depositing Pt nanoparticles and DFT calculations verify the accumulation of electrons on some areas of g-C_(3)N_(4)surface.The increased-NH_(2)groups significantly tune the electronic structure of g-C_(3)N_(4)after the modification.The generation of midgap states also affects the charge separation.Our reports provide a simple method to manage the migration of charge carriers and enable electrons directional transfer,which suppresses the recombination and improves the photocatalytic activity.展开更多
BACKGROUND Endometriosis is a common benign gynecological disease that causes dysmenorrhea in women of childbearing age.Malignant tumors derived from endometriosis are rarely reported and are found in only 1%of all pa...BACKGROUND Endometriosis is a common benign gynecological disease that causes dysmenorrhea in women of childbearing age.Malignant tumors derived from endometriosis are rarely reported and are found in only 1%of all patients with endometriosis.Here,we report a well-differentiated squamous cell carcinoma(SCC)caused by squamous metaplasia of endometriosis that co-occurred in the uterus and ovaries.CASE SUMMARY A 57-year-old postmenopausal woman had a 6-month history of irregular uterine bleeding.The uterus and adnexa were examined by computed tomography,and there were two solid cystic masses in the pelvis and right adnexa.Histological findings of surgical specimens showed well-differentiated SCC arising from squamous metaplasia of ectopic endometrial glands in the uterus and ovaries.The patient received chemotherapy after surgery and was followed up for 3 mo without metastasis.CONCLUSION The continuity between ectopic endometrial glands and SCC supports that SCC originates from ectopic endometrial glands with metaplasia towards squamous epithelium.展开更多
Circularly polarized luminescence(CPL)materials are essential for advanced optoelectronic applications,yet efficient chiral design strategies remain challenging.Axial chirality has been widely employed in the construc...Circularly polarized luminescence(CPL)materials are essential for advanced optoelectronic applications,yet efficient chiral design strategies remain challenging.Axial chirality has been widely employed in the construction of CPL materials due to its unique rigid structure.However,the focus has been primarily on the derivatives of carbon-carbon axial chirality.We herein propose a strategy for constructing carbon-nitrogen(C─N)axially chiral molecular frameworks to fully exploit the excellent chromophoric properties of nitrogen-containing heterocycles(such as carbazole).A pair of chiral emitters,(S/R)-AI-2TCFC,was designed and synthesized,exhibiting an emission peak at 578 nm both in the toluene solution and in the neat film state.It possessed typical aggregation-induced emission(AIE),thermally activated delayed fluorescence(TADF),and a luminescence dissymmetry factor(glum)of 10^(-3),demonstrating its potential for high-performance device applications.These materials were successfully applied in circularly polarized organic light-emitting diodes(CP-OLEDs),demonstrating promising electroluminescence performance.This innovative strategy not only expands the design toolbox for CPL materials but also paves the way for next-generation high-performance optoelectronic devices.展开更多
Phenolic resin-based porous composites are the promising thermal protection materials for aerospace applications.The high-temperature evolution of microstructure due to the decomposition of the resin also presents gre...Phenolic resin-based porous composites are the promising thermal protection materials for aerospace applications.The high-temperature evolution of microstructure due to the decomposition of the resin also presents great challenges to predict the internal heat and mass transport behaviors.This work investigates the effects of microstructural characteristics such as the number of pores,size distribution,pore-throats size and volume fraction on the permeation behaviors of fluid in the needle-punched short-cut fiber reinforced silicon phenolic resin-based porous composites.The specimens are prepared by the sol-gel method and the atmospheric pressure drying process and the pyrolysis experiment are conducted at 400℃and 800℃.Then,a scanning electron microscope and a Nano-CT computer tomography are applied to obtain the surface morphologies and the interior slice images of the specimens.The AVIZO software is employed to accurately extract and analyze the pore structural model and simulated calculate the absolute permeability.It is found that the small pores develop gradually during pyrolysis due to the resin decomposition and the quartz fibers rearrangement,resulting in an increase in number of large pores.Nonetheless,the equivalent radii of most pores are less than 1μm.Very few pores possess a large radius over 5μm.However,the volume fraction of these large pores exceeds 99%.In addition,with the pore size growing,the connectivity between these pores is enhanced,immediately causing an increase in number and size of the pore-throats.Larger pore and more pore-throats would add the unblocked flow channels for the fluid passing,reducing flow resistance.The seepage simulation also confirms that the absolute permeability gains significant increase after pyrolysis in all directions.For example,the absolute permeability of the pyrolyzed sample is 9.0×10^(-13)m^(2) in X direction,which is an order of magnitude greater than that of the unpyrolyzed sample.This study provides important insights for understanding the high-temperature evolution at of microstructure and the permeation behavior of fluid in porous thermal protection materials.展开更多
Photocatalysis has attracted intense attention due to its potential to solve the energy resource problem and environmental issues.The single metal atom decorated photocatalysts as a rising star become more and more po...Photocatalysis has attracted intense attention due to its potential to solve the energy resource problem and environmental issues.The single metal atom decorated photocatalysts as a rising star become more and more popular because of the unique advantages of superior catalytic activities and ultrahigh atom utilization efficiency.The key function of single metal atom catalysts in photocatalytic reactions is boosting surface redox reactions by utilizing photogenerated charges,and has been verified by various spectroscopic and microscopic techniques.Nevertheless,the activities of the single metal atoms highly depend on the binding environment in the host photocatalyst that affect the adsorption and activation of reactants as well as the reaction energy barrier.Herein,this mini review summarizes recent progress on single metal atom decorated photocatalysts,and discusses the roles of the single metal atom catalysts in different types of host photocatalysts including organic,carbon-based and inorganic materials.The remaining challenges and future perspectives on the stability and activities of single atom catalysts in photocatalytic processes are elaborated in the end.We believe that this mini review will provide valuable overview on synthetic methods of different single atom photocatalysts for researchers towards future development of highly efficient photocatalysts.展开更多
Edge computing nodes undertake an increasing number of tasks with the rise of business density.Therefore,how to efficiently allocate large-scale and dynamic workloads to edge computing resources has become a critical ...Edge computing nodes undertake an increasing number of tasks with the rise of business density.Therefore,how to efficiently allocate large-scale and dynamic workloads to edge computing resources has become a critical challenge.This study proposes an edge task scheduling approach based on an improved Double Deep Q Network(DQN),which is adopted to separate the calculations of target Q values and the selection of the action in two networks.A new reward function is designed,and a control unit is added to the experience replay unit of the agent.The management of experience data are also modified to fully utilize its value and improve learning efficiency.Reinforcement learning agents usually learn from an ignorant state,which is inefficient.As such,this study proposes a novel particle swarm optimization algorithm with an improved fitness function,which can generate optimal solutions for task scheduling.These optimized solutions are provided for the agent to pre-train network parameters to obtain a better cognition level.The proposed algorithm is compared with six other methods in simulation experiments.Results show that the proposed algorithm outperforms other benchmark methods regarding makespan.展开更多
In this study, the SiO2eCaOeP2O5 ternary component of bioactive glass particles were successfullysynthesized by sol-gel method, then the bioactive glass particles were pressed into tablets with drypressing molding tec...In this study, the SiO2eCaOeP2O5 ternary component of bioactive glass particles were successfullysynthesized by sol-gel method, then the bioactive glass particles were pressed into tablets with drypressing molding technology. The physicochemical structure, in-vitro bioactivity and biocompatibility ofBG tablets were characterized by various methods, such as XRD、SEM、FTIR, etc. The results showedthat the sol-gel bioactive glass particle was distinguished with its amorphous structure and micron-size.After being soaked in Tris-Hcl solution for 15 d, the bioactive glass tablets didn't collapse. Also, themineralization assay in vitro showed that the bioactive glass tablets had good capability of inducing theformation of hydroxycarbonate apatite (HCA) after being immersed in simulated body fluid (SBF). Inaddition, the cytotoxicity assay indicated that the osteoblast (MC3T3) grew well on the surface ofbioactive glass tablets. According to the above results, the bioactive glass tablets presented good mechanicalstrength, excellent apatite-forming activity and high biocompatibility, which demonstratedtheir potential applications in the field of bone defect repairing.展开更多
One of the major difficulties in realizing a high-dimensional frequency converter for conventional optical vortex(COV)modes stems from the difference in ring diameter of the COV modes with different topological charge...One of the major difficulties in realizing a high-dimensional frequency converter for conventional optical vortex(COV)modes stems from the difference in ring diameter of the COV modes with different topological charge numbers l.Here,we implement a high-dimensional frequency converter for perfect optical vortex(POV)modes with invariant sizes by way of the four-wave mixing(FWM)process using Bessel–Gaussian beams instead of Laguerre–Gaussian beams.The measured conversion efficiency from 1530 to 795 nm is independent of l at least in subspace l∈{-6,………,6},and the achieved conversion fidelities for two-dimensional(2D)superposed POV states exceed 97%.We further realize the frequency conversion of 3D,5D,and 7D superposition states with fidelities as high as 96.70%,89.16%,and 88.68%,respectively.The proposed scheme is implemented in hot atomic vapor.It is also compatible with the cold atomic system and may find applications in high-capacity and long-distance quantum communication.展开更多
Purpose As a fourth-generation light source,High Energy Photon Source(HEPS)has much more stringent requirements to the beam orbit stability in both horizontal and vertical directions than the previous sources due to t...Purpose As a fourth-generation light source,High Energy Photon Source(HEPS)has much more stringent requirements to the beam orbit stability in both horizontal and vertical directions than the previous sources due to the much smaller beam sizes.Methods A Fast Orbit FeedBack(FOFB)system,with the closed-loop bandwidth around 500 Hz,is needed to meet the critical requirements.The latency of the FOFB system is the key to achieve these requirements.Results Proper design and implementation of the feedback logic to have low latency is illustrated in the paper.Calculation accuracy is kept in the whole operation except for the last-minute data translation into 32-bit floating point number.展开更多
文摘This editorial critically evaluated the recent study by AlMousa et al,which examined the impact of the Arabic version of the American Academy of Or-thopedic Surgeons Foot and Ankle Outcomes Questionnaire(AAOS-FAOQ)on postoperative quality of life and recovery in Arabic-speaking patients with traumatic foot and ankle injuries.In the context of systemic linguistic exclusion in orthopedic research—where English-language journals dominated most publi-cations and non-English-speaking populations faced dual barriers of trial under-representation and semantic distortions(e.g.,mistranslations of terms like"joint instability"in Arabic)—AlMousa et al's work highlighted the transformative po-tential of culturally adapted methodologies.Their rigorous four-stage adaptation framework validated the Arabic AAOS-FAOQ as a reliable tool,enhancing ecological validity and reducing bias in patient-reported outcomes.However,limitations such as regional specificity(Gulf-centric sampling)and short follow-up periods(4 months)underscored broader challenges in non-English research:Redundant studies,prolonged hospital stays for limited English proficiency patients,and underrepresentation of certain ethnic groups in trials.To dismantle linguistic hegemony,we proposed semantic reconstruction(e.g.,integrating culturally specific indicators like"prayer posture"),dialect-aware neural tran-slation,and World Health Organization led terminology standardization.In line with these proposed solutions,AlMousa et al’s study exemplified how language-sensitive adaptations could bridge equity gaps,while future efforts would need to balance cultural specificity with cross-study comparability through AI-driven multilingual databases and policy mandates for cultural adaptation roadmaps.
基金financial support of the Henan Provincial Science and Technology Research Project(Project No.242102310322)Shangqiu Product Quality Inspection and Testing Center(Project No.2024001).
文摘The effects of yam powder(YP)on the functional properties of wheat flour noodles were investigated to improve the nutritional value of noodles and provide a scientific basis for YP application in flour products.Using wheat flour as the main ingredient,the effects of different YP substitution ratios(0,5%,10%,15%,20%,and 25%)on polyphenolic content,2,2-diphenyl-1-picrylhydrazyl(DPPH)free radical scavenging rate,and starch digestibility of the prepared noodles were analyzed in vitro.Additionally,the effects of YP water-soluble extracts,wheat flour noodles,and YP-enriched noodles(hereinafter,YP noodles)on inflammatory factors in vascular smooth muscle cells(VSMCs)treated by H_(2)O_(2)(100μM)were investigated.The results showed that YP had a substantial effect on polyphenolic content and DPPH free radical scavenging rate of wheat flour noodles,significantly increasing both values compared with those of the control group(P<0.05).The polyphenolic content reached a maximum of 2.17 mg/g in noodles with 20%YP substitution,whereas DPPH free radical scavenging rate reached a maximum of 42.10%in noodles with 25%YP substitution.With an increase in YP amount,both starch hydrolysis rate and rapidly digestible starch content of the noodles decreased gradually,whereas resistant starch content increased significantly.Moreover,50,100,and 200μg/mL of water-soluble YP and YP noodle extracts had no significant effect on the viability of VSMCs,and high concentrations of YP and YP noodle extracts resulted in cell death.Both YP and noodle extracts also reduced the secretion levels of inflammatory factors IL-6 and TNF-α in H_(2)O_(2)-treated VSMCs.Overall,YP addition reduced starch digestibility,increased antioxidative activity,and effectively improved functional quality of noodles.This study provides reference for the research and development of health-benefiting anti-inflammatory foods.
基金Supported by Huzhou City Science and Technology Plan Public Welfare Technology Application Research Project[Key Project],No.2020GZ42.
文摘BACKGROUND Bipolar disorder(BD),marked by recurring manic and depressive episodes,often coexists with anxiety disorder(AD),which increases treatment complexity and morbidity.Although quetiapine,an atypical antipsychotic,has demonstrated efficacy in treating BD and AD,further investigation is needed regarding its effectiveness and safety in patients with AD at high-risk factors for BD.AIM To explore the application and efficacy of quetiapine in combination therapy for patients with AD at high-risk factors for BD.METHODS This study included 67 patients,with two excluded,leaving 65 divided into Group A(sertraline treatment)and Group B(combination treatment).All patients received sertraline,with Group B additionally receiving quetiapine.Efficacy was assessed using the Hamilton anxiety scale(HAMA),Hamilton depression scale(HAMD),and Bech-Rafaelsen Mania sale(BRMS)throughout the treatment period.Side effects and physiological indicators were also monitored.RESULTS No significant baseline differences existed between the two groups at treatment onset.Over the treatment course,Group B exhibited significantly lower HAMA scores than Group A at the end of weeks 1 and 24.HAMD scores gradually decreased over time,with Group B consistently showing lower scores than Group A.BRMS scores decreased significantly from baseline by week 8.In Group A,27.27%of patients received zolpidem treatment compared to 10.53%in Group B,which was a significant difference.Incidence of adverse reactions did not differ significantly between groups at treatment onset,but most patients experienced relief from adverse reactions within 4 weeks.CONCLUSION Combination of quetiapine and sertraline can more rapidly alleviate anxiety and depressive symptoms in patients with AD at high-risk factors for BD,improving treatment outcomes.
文摘This editorial critically evaluated Liu et al's recent retrospective analysis of 283 Chinese patients with resectable pancreatic ductal adenocarcinoma(PDAC)that validated a preoperative computed tomography-based risk scoring system origi-nally developed in South Korea.The scoring system incorporated five parame-ters:(1)Tumor size;(2)Portal venous phase density;(3)Necrosis;(4)Peripan-creatic infiltration;and(5)Suspected metastatic lymph nodes.While demonstra-ting satisfactory recurrence prediction capability without requiring complex tech-nologies,thereby supporting clinical utility in Chinese populations,the study exhibited notable limitations.Most analyzed patients lacked neoadjuvant chemo-therapy exposure,resulting in underrepresentation of low-risk subgroups.Addi-tionally,the short follow-up duration potentially compromised long-term progno-stic assessment.Contemporary advances in radiomics coupled with machine learning have enhanced multimodal data integration for PDAC management.However,clinical implementation continues to confront challenges including variability in imaging parameters,incomplete understanding of molecular underpinnings,and confounding treatment effects.Future investigations should prioritize developing multidimensional predictive frameworks that synergize radiographic,molecular,and clinical data.Prospective multicenter validation and artificial intelligence-powered real-time risk stratification systems represent essential steps to overcome current barriers in precision medicine translation,ultimately advancing personalized therapeutic strategies for PDAC.
基金supported by the National Natural Science Foundation of China(Nos.52370158 and 22006053)Guangzhou Science and Technology Plan Project(No.2024A04J0821)Guangdong Provincial Education Science Planning Project(Higher Education Special Project)(No.2023GXJK108).
文摘Electroplating sludge(ES),a byproduct of the electroplating industry,is a significant environmental concern due to its high content of soluble heavy metals(HMs).The significance of spinel formation from ES lies in its potential for HMs enrichment and environmental remediation,offering a sustainable solution for hazardous waste management.The article delves into themultifaceted recycling of HMs-rich spinel fromES,encompassing its synthesis,metal enrichment,and thermodynamic stability.The pyro-metallurgical and hydrometallurgical processes for spinel synthesis were discussed,with a focus on the critical role of thermodynamic data in predicting the stability and formation of spinel structures.The crystallographic and magnetic properties of spinels,with their applications in environmental remediation and energy storage are highlighted.The article provides a comprehensive reviewon the recycling of HMs-rich spinel fromES,offering a means to recycle HMs,mitigate ecological harm,and contribute to a circular economy through the recovery and application of valuable materials.The selective leaching of metals from ES also faces challenges,which was limited by the separation,purification steps and high energy consumption.This high energy consumption is a significant operational cost and also contributes to environmental concerns related to carbon emissions.It is essential to address the challenges through continued research and development,improved technologies,and supportive regulatory frameworks.
文摘This editorial critically evaluated the recent study by Wang et al,which systematically investigated the efficacy of perioperative disinfection and isolation measures(including preoperative povidone-iodine disinfection,intraoperative sterile barrier techniques,and postoperative intensive care)in reducing infection rates.The study further incorporated the surgical site infection risk prediction model(constructed via the least absolute shrinkage and selection operator al-gorithm,integrating patients'baseline characteristics,surgical indicators,and regional antibiotic-resistant bacterial data),and proposed a dynamic prevention and control system termed“disinfection protocols-predictive models–real-time monitoring”.The article highlighted that preoperative risk stratification,intraoperative personalized antibiotic selection,and postoperative multidimensional monitoring(encompassing inflammatory biomarkers,imaging,and microbiological testing)enabled the precise identification of high-risk patients and optimized intervention thresholds.Future research is deemed necessary to validate the synergistic effects of disinfection protocols and predictive models through large-scale multicenter studies,combined with advanced intraoperative rapid microbial detection technologies.This approach aims to establish standardized infection control protocols tailored for precision medicine and regional adaptability.Future research should prioritize validating the synergistic effects of disinfection protocols and predictive models via multi-center studies,while incorporating advanced rapid intraoperative microbial detection technologies to develop standardized infection prevention and control procedures.Such efforts will enhance the implementation of precise and regionally adaptive infection control strategies.
基金support from the Scarce and Quality Economic Forest Engineering Technology Research Center(2022GCZX002)the Key Lab.of Biomass Energy and Material,Jiangsu Province(Grant No.JSBEM-S-202305)the Forestry Scientific Research Monitoring Project of Guangdong Province(2025KJXM01).
文摘In this study,3,4-Epoxycyclohexylmethyl 3,4-epoxycyclohexanecarboxylate(ECC)and refined Camellia oleifera seed oil(RCOSO)obtained from saponification and acidified hydrolysis has been used as raw materials to perform ring-opening reactions for the preparation of cyclohexyl acrylate derivative(CAR).The structure of the synthesized product was characterized using infrared spectroscopy,Raman spectroscopy,and nuclear magnetic resonance spectroscopy.CAR was employed as a plasticizer to produce modified polyvinyl chloride(PVC)films,dioctyl phthalate plasticizer(DOP)used in reference samples to investigate the influence of different plasticizer molecular structures on the properties of PVC films.Observation suggested that(1)CAR plasticizer was successfully synthesized;(2)CAR can interact with PVC,exhibiting good compatibility;(3)PVC films contain CAR showed improved thermal stability,hydrophilicity,and tensile strength.Therefore,CAR has the potential to replace DOP as a plasticizer for PVC.
基金Supported by the National Natural Science Foundation of China,No. 30271450the Natural Science Foundation of Zhejiang Province,No. 300466
文摘AIM： To provide the expression profile of serine protease SNC19/matriptase and its inhibitor hepatocyte growth factor activator inhibitor type 1 （HAI-1） in normal and malignant tissues of gastrointestinal tract at mRNA level for further study on their correlations with tumor progression and metastasis. METHODS： Total RNAs were prepared from 37 samples of colorectal cancer tissues, 40 samples of gastric cancer tissues, and their adjacent normal tissues. The expression of SNC19/matriptase and HAI-1 in these samples was detected by real-time fluorescent quantitative PCR using glyceraldehyde-3-phosphate dehydrogenase as internal standard, and the clinical significance for the correlation with clinicopathological parameters was evaluated. RESULTS： In gastric cancer tissues the expression of HAI-1 and SNC19/matriptase was significantly lower than that in the corresponding adjacent normal tissues （Z = -3.280, P= 0.006; Z= -4.651, P= 0.000）. HAI-1：SNC19/matriptase ratio showed no difference between normal and malignant tissues （P〉0.05）. Analysis of clinicopathological parameters showed decreased expression of HAI-1 and HAI-1：SNC19/ matriptase ratio associated with stage Ⅲ/Ⅳ gastric tumors as compared to stage Ⅰ/Ⅱ ones （Z= -2.140, P= 0.031; Z = -2.155, P = 0.031）, and with lymph node-positive gastric cancer tissues as compared to lymph node-negative ones （Z = -2.081, P = 0.036; Z= -2.686, P = 0.006）. The expression of SNC19/matriptase had no relationship with stages and lymph node metastasis （P〉0.05）. The expression of HAI-1 and HAI-1：SNC19/matriptase ratio increased in well-differentiated gastric cancer tissues, but there was no statistical significance （P〉0.05）. The difference of SNC19/matriptase expression was not significant in gastric cancer tissues of different histological differentiation status （P〉0.05）. In colorectal cancer tissues, the expression of HAI-1 and SNC19/matriptase was also markedly lower than that in their adjacent normal tissues （Z= -3.100, P = 0.002; Z= -2.731, P = 0.006）, whereas HAI-1：SNC19/matriptase ratio showed no difference. Decreased expression of HAI-1 was associated with increased invasive depth and lymph node metastasis, but there was no statistical significance （P〉0.05）. The difference of SNC19/matriptase expression and HAI-1： SNC19/matriptase ratio was not significant in different stages and different lymph node metastasis status （P〉0.05）. The expression of SNC19/matriptase, HAI-1 or HAI-1： SNC19/matriptase ratio showed no difference in colorectal cancer tissues of different histological differentiation status （P〉0.05）. CONCLUSION： The expressions of SNC19/matriptase and its inhibitor HAI-1 are decreased in gastrointestinal cancer tissues compared to their normal counterparts, and the decreased expression of HAI-1 may correlate with invasion and lymph node metastasis. The possible mechanisms involved need to be further investigated.
基金supported by the National Natural Science Foundation of China(5187051675)。
文摘To improve the safety and driving stability of the autonomous heavy truck, it is necessary to consider the differences of driving behavior and drivable trajectories between the heavy trucks and passenger cars. This study proposes a probabilistic decision-making and trajectory planning framework for the autonomous heavy trucks. Firstly, the driving decision process is divided into intention generation and feasibility evaluations, which are realized using the utility theory and risk assessment, respectively. Subsequently the driving decision is made and sent to the trajectory planning module. In order to reflect the greater risks of the truck to other surrounding vehicles, the aggressiveness index(AI) is proposed and quantified to infer the asymmetrical risk level of lane-change maneuver. In the planning stage, the lateral and roll dynamics stability domains are developed as the constraints to exclude the candidate trajectories that would cause vehicle instability. Finally, the simulation results are compared between the proposed model and the artificial potential filed model in the scenarios extracted from the naturalistic driving data. It is shown that the proposed framework can provide the human-like lane-change decisions and truck-friendly trajectories, and performs well in dynamic driving environments.
基金This research was supported by the National Natural Science Foundation of China(41672250,42177076)the Natural Science Foundation of Shaanxi Province(2019JLZ-03)the Key R&D Projects of Shaanxi Province(2021ZDLSF05-09).
文摘At present,investigation about the relationship between the change of groundwater level and vegetation mostly focuses on specific watersheds,i.e.limited in river catchment scale.Understanding the change of groundwater level on vegetation in the basin or large scale,be urgently needed.To fill this gap,two typical arid areas in the west of China(Tarim Basin and Qaidam Basin)were chosen the a typical research area.The vegetation status was evaluated via normalization difference vegetation index(NDVI)from 2000 to 2016,sourced from MODN1F dataset.The data used to reflect climate change were download from CMDSC(http://data.cma.cn).Groundwater level data was collected from monitor wells.Then,the relationship of vegetation and climate change was established with univariate linear regression and correlation analysis approach.Results show that:Generally,NDVI value in the study area decreased before 2004 then increased in the research period.Severe degradation was observed in the center of the basin.The area with an NDVI value>0.5 decreased from 12%to 6%between 2000 and 2004.From 2004 to 2014,the vegetation in the study area was gradually restored.The whole coverage of Qaidam Basin was low.And the NDVI around East Taigener salt-lake degraded significantly,from 0.596 to 0.005,2014 and 2016,respectively.The fluctuation of groundwater level is the main reason for the change of surface vegetation coverage during the vegetation degradation in the basin.However,the average annual precipitation in the study area is low,which is not enough to have a significant impact on vegetation growth.The annual average precipitation showed an increase trend during the vegetation restoration in the basin,which alleviates the water shortage of vegetation growth in the region.Meanwhile,the dependence of surface vegetation on groundwater is obviously weakened with the correlation index is−0.248.The research results are of some significance to eco-environment protection in the arid area of western China.
基金supported by the National Natural Science Foundation of China(Nos.21703097 and 21972172)South-ern University of Science and Technology(SUSTech)start fund through the Shenzhen Peacock Talent program,the Shenzhen Ba-sic Research Fund project(No.JCYJ20150507170334573)the Guangdong Innovative and Entrepreneurial Research Team Program(No.2016ZT06N532).
文摘It is a prospective strategy to produce sustainable energy by photocatalytic overall water splitting(POWS).This work aims to develop a simple method for integrating a donor-acceptor system into polymeric car-bon nitride(PCN)structure,which could accelerate the charge separation significantly.In the as-prepared photocatalyst(COCNT),carbon and oxygen were successfully incorporated into the framework of PCN,and the chemical environment of C and O was well probed by X-ray absorption near-edge structure(XANES)and X-ray photoelectron spectroscopy(XPS).It showed that the C-containing and O-containing segments of COCNT played the role of a donor,while the heptazine part played the role of an acceptor.In addition,Density-functional-theory(DFT)calculations confirmed the spatial split of the highest occupied molec-ular orbital(HOMO)and lowest unoccupied molecular orbital(LUMO)for promoting charge separation.Impressively,COCNT could efficiently split pure water to generate hydrogen and oxygen.And,the photo-catalytic hydrogen evolution rate over COCNT(1550.9μmol g^(-1)h^(-1))is about 17-fold higher than that of PCN.Finally,we proposed a possible photocatalytic mechanism to explain the above results.
基金supported by Shenzhen Key Laboratory of Solid State Batteries(ZDSYS20180208184346531)Guangdong Provincial Key Laboratory of Energy Materials for Electric Power(2018B030322001)+3 种基金Guangdong Provincial Key Laboratory of Catalysis(2020B121201002)Shenzhen Clean Energy Research Institute(CERI-KY-2019-003)the National Natural Science Foundation of China(2017M611446)supported by the Core Research Facilities at SUSTech that receives support from a Presidential fund and the Development and Reform Commission of Shenzhen Municipality。
文摘The random mobility of charge carriers is a main factor causing the low photocatalytic efficiency of gCN.Thus,the controllable migration of charge carriers is a rational strategy to suppress the charge recombination and facilitate charge separation.Herein,an ethylenediamine modified g-C_(3)N_(4)displays improved photocatalytic activity.The excellent charge separation efficiency is confirmed to be a key factor for the enhancement.The TEM observation after photo-depositing Pt nanoparticles and DFT calculations verify the accumulation of electrons on some areas of g-C_(3)N_(4)surface.The increased-NH_(2)groups significantly tune the electronic structure of g-C_(3)N_(4)after the modification.The generation of midgap states also affects the charge separation.Our reports provide a simple method to manage the migration of charge carriers and enable electrons directional transfer,which suppresses the recombination and improves the photocatalytic activity.
文摘BACKGROUND Endometriosis is a common benign gynecological disease that causes dysmenorrhea in women of childbearing age.Malignant tumors derived from endometriosis are rarely reported and are found in only 1%of all patients with endometriosis.Here,we report a well-differentiated squamous cell carcinoma(SCC)caused by squamous metaplasia of endometriosis that co-occurred in the uterus and ovaries.CASE SUMMARY A 57-year-old postmenopausal woman had a 6-month history of irregular uterine bleeding.The uterus and adnexa were examined by computed tomography,and there were two solid cystic masses in the pelvis and right adnexa.Histological findings of surgical specimens showed well-differentiated SCC arising from squamous metaplasia of ectopic endometrial glands in the uterus and ovaries.The patient received chemotherapy after surgery and was followed up for 3 mo without metastasis.CONCLUSION The continuity between ectopic endometrial glands and SCC supports that SCC originates from ectopic endometrial glands with metaplasia towards squamous epithelium.
基金supported by the China Postdoctoral Science Foundation(2023M743353 and 2024T170890)the National Natural Science Foundation of China(22401241,52303382,52273197,52333007,and 22275040)+3 种基金the National Key Research and Development Program of China(2023YFB3810001)Shenzhen Key Laboratory of Functional Aggregate Materials(ZDSYS20211021111400001)the Science,Technology,and Innovation Commission of Shenzhen Municipality(KQTD20210811090142053,GJHZ20210705141810031,JCYJ20220818103007014,JCYJ20220530143805012,and JCYJ20210324134613038)theInnovation and Technology Commission(ITC-CNERC14SC01).
文摘Circularly polarized luminescence(CPL)materials are essential for advanced optoelectronic applications,yet efficient chiral design strategies remain challenging.Axial chirality has been widely employed in the construction of CPL materials due to its unique rigid structure.However,the focus has been primarily on the derivatives of carbon-carbon axial chirality.We herein propose a strategy for constructing carbon-nitrogen(C─N)axially chiral molecular frameworks to fully exploit the excellent chromophoric properties of nitrogen-containing heterocycles(such as carbazole).A pair of chiral emitters,(S/R)-AI-2TCFC,was designed and synthesized,exhibiting an emission peak at 578 nm both in the toluene solution and in the neat film state.It possessed typical aggregation-induced emission(AIE),thermally activated delayed fluorescence(TADF),and a luminescence dissymmetry factor(glum)of 10^(-3),demonstrating its potential for high-performance device applications.These materials were successfully applied in circularly polarized organic light-emitting diodes(CP-OLEDs),demonstrating promising electroluminescence performance.This innovative strategy not only expands the design toolbox for CPL materials but also paves the way for next-generation high-performance optoelectronic devices.
基金supported by the Projection of State Key Laboratory of Environment-friendly Energy Materials,Southwest University of Science and Technology(20FKSY23)。
文摘Phenolic resin-based porous composites are the promising thermal protection materials for aerospace applications.The high-temperature evolution of microstructure due to the decomposition of the resin also presents great challenges to predict the internal heat and mass transport behaviors.This work investigates the effects of microstructural characteristics such as the number of pores,size distribution,pore-throats size and volume fraction on the permeation behaviors of fluid in the needle-punched short-cut fiber reinforced silicon phenolic resin-based porous composites.The specimens are prepared by the sol-gel method and the atmospheric pressure drying process and the pyrolysis experiment are conducted at 400℃and 800℃.Then,a scanning electron microscope and a Nano-CT computer tomography are applied to obtain the surface morphologies and the interior slice images of the specimens.The AVIZO software is employed to accurately extract and analyze the pore structural model and simulated calculate the absolute permeability.It is found that the small pores develop gradually during pyrolysis due to the resin decomposition and the quartz fibers rearrangement,resulting in an increase in number of large pores.Nonetheless,the equivalent radii of most pores are less than 1μm.Very few pores possess a large radius over 5μm.However,the volume fraction of these large pores exceeds 99%.In addition,with the pore size growing,the connectivity between these pores is enhanced,immediately causing an increase in number and size of the pore-throats.Larger pore and more pore-throats would add the unblocked flow channels for the fluid passing,reducing flow resistance.The seepage simulation also confirms that the absolute permeability gains significant increase after pyrolysis in all directions.For example,the absolute permeability of the pyrolyzed sample is 9.0×10^(-13)m^(2) in X direction,which is an order of magnitude greater than that of the unpyrolyzed sample.This study provides important insights for understanding the high-temperature evolution at of microstructure and the permeation behavior of fluid in porous thermal protection materials.
基金the Ministry of Education,Singapore,under AcRF-Tier2(MOE2018-T2-1-017),AcRFTierl(MOE2019-T1-002-012,RG102/19).
文摘Photocatalysis has attracted intense attention due to its potential to solve the energy resource problem and environmental issues.The single metal atom decorated photocatalysts as a rising star become more and more popular because of the unique advantages of superior catalytic activities and ultrahigh atom utilization efficiency.The key function of single metal atom catalysts in photocatalytic reactions is boosting surface redox reactions by utilizing photogenerated charges,and has been verified by various spectroscopic and microscopic techniques.Nevertheless,the activities of the single metal atoms highly depend on the binding environment in the host photocatalyst that affect the adsorption and activation of reactants as well as the reaction energy barrier.Herein,this mini review summarizes recent progress on single metal atom decorated photocatalysts,and discusses the roles of the single metal atom catalysts in different types of host photocatalysts including organic,carbon-based and inorganic materials.The remaining challenges and future perspectives on the stability and activities of single atom catalysts in photocatalytic processes are elaborated in the end.We believe that this mini review will provide valuable overview on synthetic methods of different single atom photocatalysts for researchers towards future development of highly efficient photocatalysts.
基金supported by the National Key Research and Development Program of China(No.2021YFE0116900)National Natural Science Foundation of China(Nos.42275157,62002276,and 41975142)Major Program of the National Social Science Fund of China(No.17ZDA092).
文摘Edge computing nodes undertake an increasing number of tasks with the rise of business density.Therefore,how to efficiently allocate large-scale and dynamic workloads to edge computing resources has become a critical challenge.This study proposes an edge task scheduling approach based on an improved Double Deep Q Network(DQN),which is adopted to separate the calculations of target Q values and the selection of the action in two networks.A new reward function is designed,and a control unit is added to the experience replay unit of the agent.The management of experience data are also modified to fully utilize its value and improve learning efficiency.Reinforcement learning agents usually learn from an ignorant state,which is inefficient.As such,this study proposes a novel particle swarm optimization algorithm with an improved fitness function,which can generate optimal solutions for task scheduling.These optimized solutions are provided for the agent to pre-train network parameters to obtain a better cognition level.The proposed algorithm is compared with six other methods in simulation experiments.Results show that the proposed algorithm outperforms other benchmark methods regarding makespan.
基金This work was supported by the Joint Funds of the National Natural Science Foundation of China(Grant No.U1501245)the Fundamental Research Funds for the Central Universities(2015ZP020)+1 种基金the National Natural Science Foundation of China(Grant No.51672088)the science and technology innovation team project of Foshan(No.2015IT100062).
文摘In this study, the SiO2eCaOeP2O5 ternary component of bioactive glass particles were successfullysynthesized by sol-gel method, then the bioactive glass particles were pressed into tablets with drypressing molding technology. The physicochemical structure, in-vitro bioactivity and biocompatibility ofBG tablets were characterized by various methods, such as XRD、SEM、FTIR, etc. The results showedthat the sol-gel bioactive glass particle was distinguished with its amorphous structure and micron-size.After being soaked in Tris-Hcl solution for 15 d, the bioactive glass tablets didn't collapse. Also, themineralization assay in vitro showed that the bioactive glass tablets had good capability of inducing theformation of hydroxycarbonate apatite (HCA) after being immersed in simulated body fluid (SBF). Inaddition, the cytotoxicity assay indicated that the osteoblast (MC3T3) grew well on the surface ofbioactive glass tablets. According to the above results, the bioactive glass tablets presented good mechanicalstrength, excellent apatite-forming activity and high biocompatibility, which demonstratedtheir potential applications in the field of bone defect repairing.
基金supported by the National Key R&D Program of China(No.2017YFA0304800)the Anhui Initiative in Quantum Information Technologies(No.AHY020200)+3 种基金the National Natural Science Foundation of China(Nos.U20A20218,61722510,11934013,11604322,and 12204461)the Innovation Fund from CAS,Youth Innovation Promotion Association of CAS(No.2018490)the Anhui Provincial Key Research and Development Project(No.2022b13020002)the Anhui Provincial Candidates for Academic and Technical Leaders Foundation(No.2019H208)。
文摘One of the major difficulties in realizing a high-dimensional frequency converter for conventional optical vortex(COV)modes stems from the difference in ring diameter of the COV modes with different topological charge numbers l.Here,we implement a high-dimensional frequency converter for perfect optical vortex(POV)modes with invariant sizes by way of the four-wave mixing(FWM)process using Bessel–Gaussian beams instead of Laguerre–Gaussian beams.The measured conversion efficiency from 1530 to 795 nm is independent of l at least in subspace l∈{-6,………,6},and the achieved conversion fidelities for two-dimensional(2D)superposed POV states exceed 97%.We further realize the frequency conversion of 3D,5D,and 7D superposition states with fidelities as high as 96.70%,89.16%,and 88.68%,respectively.The proposed scheme is implemented in hot atomic vapor.It is also compatible with the cold atomic system and may find applications in high-capacity and long-distance quantum communication.
基金This work is supported by Youth Innovation Promotion Association(Y9291420K2).
文摘Purpose As a fourth-generation light source,High Energy Photon Source(HEPS)has much more stringent requirements to the beam orbit stability in both horizontal and vertical directions than the previous sources due to the much smaller beam sizes.Methods A Fast Orbit FeedBack(FOFB)system,with the closed-loop bandwidth around 500 Hz,is needed to meet the critical requirements.The latency of the FOFB system is the key to achieve these requirements.Results Proper design and implementation of the feedback logic to have low latency is illustrated in the paper.Calculation accuracy is kept in the whole operation except for the last-minute data translation into 32-bit floating point number.
