AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing techn...AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing technique during a 1-year follow-up period.METHODS:This study included 74 eyes from 37 patients,comprising 17 males and 20 females,with a mean age of 51.74±7.80 years.Using a coin toss method,one eye per patient was randomly selected for improved anterior capsular polishing,while the other eye received standard irrigation/aspiration(I/A)polishing.The polishing group consisted of 37 eyes,including 21 right and 16 left eyes,while the control group comprised the contralateral fellow eyes of the same individuals in the polishing group.Visual acuity and quality of the patients were evaluated before surgery and at 1 wk,1,6,and 12 mo after surgery.The OPD-Scan III was utilized to assess high-order aberrations,while the optical quality analysis system(OQAS)was employed to evaluate modulation transfer function(MTF cutoff),Strehl ratio(SR),and objective scatter index(OSI)for the purpose of visual quality assessment.Paired t-tests and repeated measures analysis of variance(ANOVA)were utilized to compare the results,and the SNK-q post hoc test was applied to identify significant differences.RESULTS:The polishing group’s uncorrected distant visual acuity(UDVA)and uncorrected near visual acuity(UNVA)significantly improved 1-week post-surgery(all P<0.05).At 12-months,UDVA,UNVA,and corrected distant visual acuity(CDVA)were better than the control group(P<0.05).The MTF cutoff,SR,OSI,and high-order aberrations in the polishing group also showed significant improvements compared to the control group at 12 mo(P<0.05).CONCLUSION:The improved capsular polishing method has been demonstrated to effectively maintain visual acuity and visual quality in patients with MIOL after FLACS within 1 a.展开更多
Carbon fibers(CFs)with notable comprehensive properties,such as light weight,high specific strength,and stiffness,have garnered considerable interest in both academic and industrial fields due to their diverse and adv...Carbon fibers(CFs)with notable comprehensive properties,such as light weight,high specific strength,and stiffness,have garnered considerable interest in both academic and industrial fields due to their diverse and advanced applications.However,the commonly utilized precursors,such as polyacrylonitrile and pitch,exhibit a lack of environmental sustainability,and their costs are heavily reliant on fluctuating petroleum prices.To meet the substantial market demand for CFs,significant efforts have been made to develop cost-effective and sustainable CFs derived from biomass.Lignin,the most abundant polyphenolic compound in nature,is emerging as a promising precursor which is well-suited for the production of CFs due to its renewable nature,low cost,high carbon content,and aromatic structures.Nevertheless,the majority of lignin raw materials are currently derived from pulping and biorefining industrial by-products,which are diverse and heterogeneous in nature,restricting the industrialization of lignin-derived CFs.This review classifies fossil-derived and biomass-derived CFs,starting from the sources and chemical structures of raw lignin,and outlines the preparation methods linked to the performance of lignin-derived CFs.A comprehensive discussion is presented on the relationship between the structural characteristics of lignin,spinning preparation,and structure-morphology-property of ligninderived CFs.Additionally,the potential applications of these materials in various domains,including energy,catalysis,composites,and other advanced products,are also described with the objective of spotlighting the unique merits of lignin.Finally,the current challenges faced and future prospects for the advancement of lignin-derived CFs are proposed.展开更多
Five cadmium naphthalene-diphosphonates,formulated as[Cd_(1.5)(1,4-ndpaH_(2))2(4,4'-bpyH)(4,4'-bpy)0.5(H_(2)O)_(2)]2(1),[Cd(1,4-ndpaH_(2))(1,4-bib)0.5(H_(2)O)](2),[Cd(1,4-ndpaH3)2(1,2-dpe)(H_(2)O)]·(1,2-d...Five cadmium naphthalene-diphosphonates,formulated as[Cd_(1.5)(1,4-ndpaH_(2))2(4,4'-bpyH)(4,4'-bpy)0.5(H_(2)O)_(2)]2(1),[Cd(1,4-ndpaH_(2))(1,4-bib)0.5(H_(2)O)](2),[Cd(1,4-ndpaH3)2(1,2-dpe)(H_(2)O)]·(1,2-dpe)·7H_(2)O(3),(1,2-bixH)[Cd3(1,4-ndpaH)(1,4-ndpaH_(2))2(H_(2)O)_(2)](4),and[Cd(1,4-ndpaH_(2))(H_(2)O)]·H_(2)O(5),have been synthesized from the selfassembly reactions of 1,4-naphthalenediphosphonic acid(1,4-ndpaH4)with Cd(NO3)2·4H_(2)O by introducing auxiliary ligands with variation of rigidity,such as 4,4'-bipyridine(4,4'-bpy),1,4-bis(1-imidazolyl)benzene(1,4-bib),1,2-di(4-pyridyl)ethylene(1,2-dpe),1,3-di(4-pyridyl)propane(1,3-dpp),and bis(imidazol-1-ylmethyl)benzene(1,2-bix),respectively.Structure resolution by single-crystal X-ray diffraction reveals that compound 1 possesses a layered framework,in which the{Cd3(PO2)2}trimers made up of corner-sharing two{CdO4N2}and one{CdO6}octahedra are connected by phosphonate groups,forming a ribbon,which are cross-linked by 4,4'-bipy ligands,forming a 2D layer.Compound 2 shows a 3D open-framework structure,where chains of corner-sharing{CdO4N}trigonal bipyramids and{PO3C}tetrahedra are cross-linked by 1,4-bib and/or phosphonate groups.A 1D ladder-like chain structure is found in compound 3,where the ladder-like chains made up of corner-sharing{CdO5N}octahedra and{PO3C}tetra hedra are connected by 1,4-ndpaH_(2)^(2-).Both compounds 4 and 5 obtained by the introduction of flexible ligands during the synthesis show a 2D layered structure,which is formed by ligand crosslinking double metal chains.Interestingly,In 4,flexible 1,2-bix was singly protonated,as vip molecules,filled between layer and layer,while flexible ligand 1,3-dpp is absent in 5.Photophysical measurements indicate that compounds 1-5 show ligand-centered emissions.展开更多
In order to address the current inability of screen printing to monitor printing pressure online,an online printing pressure monitoring system applied to screen printing machines was designed in this study.In this stu...In order to address the current inability of screen printing to monitor printing pressure online,an online printing pressure monitoring system applied to screen printing machines was designed in this study.In this study,the consistency of printed electrodes was measured by using a confocal microscope and the pressure distribution detected by online pressure monitoring system was compared to investigate the relationship.The results demonstrated the relationship between printing pressure and the consistency of printed electrodes.As printing pressure increases,the ink layer at the corresponding position becomes thicker and that higher printing pressure enhances the consistency of the printed electrodes.The experiment confirms the feasibility of the online pressure monitoring system,which aids in predicting and controlling the consistency of printed electrodes,thereby improving their performance.展开更多
The solidification and corrosion behavior of the Ti/B added Zn-Al-Mg alloys were experimentally investigated by means of microstructure characterization and electrochemical test.The basic calculations were carried out...The solidification and corrosion behavior of the Ti/B added Zn-Al-Mg alloys were experimentally investigated by means of microstructure characterization and electrochemical test.The basic calculations were carried out to predict the characteristics of the Ti-added Zn-Al-Mg alloys.The Zn-Al-Mg ingots with minor doping of Ti/B were prepared and solidified under different cooling rate,including air cooling,water quenching and furnace cooling.The scanning electron microscopy(SEM)and the X-ray diffraction method(XRD)were used to determine the microstructures and phase types of the alloy samples.It could be discovered that trace TiAl3 particles were dispersed in the Ti/B added alloy samples which provide the heterogeneous nucleation sites to refine the size of the dendrites and the eutectic microstructures.More fined microstructures with the addition of both Ti and B were obtained compared with those with the merely addition of Ti,and the water cooled alloys presented the finest microstructures due to the fastest cooling rate.It could also be noticed that with the increasing solidification rate,the percentage of the MgZn_(2) phase turned out to be higher because of the Mg_(2)Zn_(11)↔MgZn_(2) transition,which is in consistent with the results in the actual hot-dip galvanizing process.Electrochemical experiments in the previous work included methods the of the Tafel polarization test and the electrochemical impedance spectroscopy test(EIS).Results show that the quenched Zn-Al-Mg alloy with the addition of both Ti and B takes on best corrosion resistance.Consequently,the addition of certain amount of Ti/B elements and the appropriate elevation of the cooling rate will be the practicable approaches to optimize the microstructure and the corrosion resistance of the Zn-Al-Mg coatings in the actual galvanizing process.展开更多
This paper presents a photonic crystal(PhC)line-defect slow-light waveguide modified by resonant rings.We introduce resonant rings into the line defect,constructing a slow-light waveguide with high normalized delay ba...This paper presents a photonic crystal(PhC)line-defect slow-light waveguide modified by resonant rings.We introduce resonant rings into the line defect,constructing a slow-light waveguide with high normalized delay bandwidth product(NDBP)and low group velocity dispersion(GVD).We simulate,analyze,and optimize the structural parameters of this slow-light waveguide using the finite difference time domain(FDTD)method,theoretically achieving a maximum group index of 3.7,maximum bandwidth of 15.6 nm,and maximum NDBP of 0.4416 for slow-light effect.The resonant ring-modified PhC slow-light waveguide designed in this paper exhibits GVD lower than the order of 10^(−20)s^(2)/m over a normalized frequency range from 0.3554 to 0.4175.This study is expected to provide theoretical references for the study of slow-light buffering devices based on PhCs with high NDBP values.展开更多
OBJECTIVE:To evaluate the effect of Yiqi Liangxue Shengji prescription(益气凉血生肌方,YQLXSJ)on cardiac function and outcomes in acute myocardial infarction(AMI)patients with myocardial ischemiareperfusion injury(MIRI...OBJECTIVE:To evaluate the effect of Yiqi Liangxue Shengji prescription(益气凉血生肌方,YQLXSJ)on cardiac function and outcomes in acute myocardial infarction(AMI)patients with myocardial ischemiareperfusion injury(MIRI)and to determine its clinical efficacy.METHODS:This prospective,randomized,double-blind,placebo-controlled trial enrolled hospitalized patients with AMI who underwent percutaneous coronary intervention and experienced MIRI either intraoperatively or postoperatively.Participants were randomly allocated to the treatment group,which received YQLXSJ,or the control group,which received a placebo,concurrent with standard Western Medicine therapy.The intervention period lasted 8 weeks.The primary outcome measure was left ventricular ejection fraction(LVEF),determined by echocardiography.Secondary outcomes included Nterminal pro brain natriuretic peptide(NT-pro BNP)and cardiac troponin I(cTnI)levels,left ventricular internal diameter,major adverse cardiovascular events(MACE),angina pectoris scores,and Chinese medicine evidence scores.RESULTS:Following 8 weeks of intervention,the treatment group demonstrated a significant increase in LVEF and a marked reduction in NT-pro BNP when compared to the control group.There was also a significant decrease in peak cTnI levels,Chinese medicine evidence scores,and angina pectoris scores.The control group's left ventricular end-systolic diameter(LVESD)significantly increased compared to baseline after 8 weeks(P<0.05),whereas the treatment group's LVESD showed no significant change from baseline(P>0.05).Although the treatment group showed a downward trend in MACE incidence compared to the control group,this difference was not statistically significant(P>0.05).CONCLUSIONS:This study demonstrated that the addition of YQLXSJ to standard therapy can improve cardiac function and alleviate clinical symptoms in AMI patients with MIRI,and also showed a potential to mitigate the incidence of MACE.Furthermore,YQLXSJ displayed a favorable safety profile in clinical application.展开更多
The March 11,2011,MW9.0 Tohoku-Oki earthquake,in Japan,caused rapid strain release near the epicenter,while the Boso Peninsula,located farther away,experienced stress redistribution,leading to changes in the recurrenc...The March 11,2011,MW9.0 Tohoku-Oki earthquake,in Japan,caused rapid strain release near the epicenter,while the Boso Peninsula,located farther away,experienced stress redistribution,leading to changes in the recurrence interval of slow slip events(SSEs)and regional strain.This study focuses on three detected post-2011 Boso SSEs,utilizing a segmented model displacement time series measured by Global Navigation Satellite System(GNSS)to calculate velocity and strain rate fields for eight periods before,during,and after the SSEs.Results show that the 2011 earthquake and the three SSEs significantly alter the velocity field in the Boso region,with SSE velocities predominantly oriented southeast,reaching maximum values of 26.9 cm/a,10.6 cm/a,and 38.5 cm/adnearly opposite to non-SSE periods.After the third SSE,the velocity field nearly returns to its pre-earthquake state,with a maximum of 1.8 cm/a.The maximum shear strain rates during the three SSEs are 25.88×10^(-7) a^(-1),11.38×10^(-7) a^(-1),and 29.02×10^(-7) a^(-1)(i.e.,per annum),significantly higher than those during non-slow slip periods,with principal strain rates following a similar pattern.The spatial distribution of strain rates during the SSEs indicates greater deformation compared to the non-slip periods,dominated by northwest-southeast extension and southwest-northeast compression.Spatiotemporal analysis reveals a strong correlation between seismic frequency and strain rate during the SSEs,with time correlation coefficients of 0.85,0.88,and 0.9.Although larger accumulated strain results in stronger strain release during the latter two SSEs,not all strain is fully released,suggesting that earthquake swarms accompanying the SSEs may contribute to the partial release of unreleased strain.This study,through the analysis of GNSS data,evaluates the spatiotemporal distribution of strain fields during periodic SSEs,contributing to further research on strain accumulation and release,and aiding in the analysis of this regional seismic activity.展开更多
文摘AIM:To assess the visual acuity and visual quality of cataract patients who received femtosecond laser-assisted cataract surgery(FLACS)and multifocal intraocular lens(MIOL)implantation with an improved polishing technique during a 1-year follow-up period.METHODS:This study included 74 eyes from 37 patients,comprising 17 males and 20 females,with a mean age of 51.74±7.80 years.Using a coin toss method,one eye per patient was randomly selected for improved anterior capsular polishing,while the other eye received standard irrigation/aspiration(I/A)polishing.The polishing group consisted of 37 eyes,including 21 right and 16 left eyes,while the control group comprised the contralateral fellow eyes of the same individuals in the polishing group.Visual acuity and quality of the patients were evaluated before surgery and at 1 wk,1,6,and 12 mo after surgery.The OPD-Scan III was utilized to assess high-order aberrations,while the optical quality analysis system(OQAS)was employed to evaluate modulation transfer function(MTF cutoff),Strehl ratio(SR),and objective scatter index(OSI)for the purpose of visual quality assessment.Paired t-tests and repeated measures analysis of variance(ANOVA)were utilized to compare the results,and the SNK-q post hoc test was applied to identify significant differences.RESULTS:The polishing group’s uncorrected distant visual acuity(UDVA)and uncorrected near visual acuity(UNVA)significantly improved 1-week post-surgery(all P<0.05).At 12-months,UDVA,UNVA,and corrected distant visual acuity(CDVA)were better than the control group(P<0.05).The MTF cutoff,SR,OSI,and high-order aberrations in the polishing group also showed significant improvements compared to the control group at 12 mo(P<0.05).CONCLUSION:The improved capsular polishing method has been demonstrated to effectively maintain visual acuity and visual quality in patients with MIOL after FLACS within 1 a.
基金National Natural Science Foundation of China,Grant/Award Numbers:32171717,32271814Natural Science Foundation of Tianjin Municipality,Grant/Award Numbers:24JCJQJC00030,22JCYBJC01560,23JCZDJC00630China Postdoctoral Science Foundation,Grant/Award Number:2023M740562。
文摘Carbon fibers(CFs)with notable comprehensive properties,such as light weight,high specific strength,and stiffness,have garnered considerable interest in both academic and industrial fields due to their diverse and advanced applications.However,the commonly utilized precursors,such as polyacrylonitrile and pitch,exhibit a lack of environmental sustainability,and their costs are heavily reliant on fluctuating petroleum prices.To meet the substantial market demand for CFs,significant efforts have been made to develop cost-effective and sustainable CFs derived from biomass.Lignin,the most abundant polyphenolic compound in nature,is emerging as a promising precursor which is well-suited for the production of CFs due to its renewable nature,low cost,high carbon content,and aromatic structures.Nevertheless,the majority of lignin raw materials are currently derived from pulping and biorefining industrial by-products,which are diverse and heterogeneous in nature,restricting the industrialization of lignin-derived CFs.This review classifies fossil-derived and biomass-derived CFs,starting from the sources and chemical structures of raw lignin,and outlines the preparation methods linked to the performance of lignin-derived CFs.A comprehensive discussion is presented on the relationship between the structural characteristics of lignin,spinning preparation,and structure-morphology-property of ligninderived CFs.Additionally,the potential applications of these materials in various domains,including energy,catalysis,composites,and other advanced products,are also described with the objective of spotlighting the unique merits of lignin.Finally,the current challenges faced and future prospects for the advancement of lignin-derived CFs are proposed.
文摘Five cadmium naphthalene-diphosphonates,formulated as[Cd_(1.5)(1,4-ndpaH_(2))2(4,4'-bpyH)(4,4'-bpy)0.5(H_(2)O)_(2)]2(1),[Cd(1,4-ndpaH_(2))(1,4-bib)0.5(H_(2)O)](2),[Cd(1,4-ndpaH3)2(1,2-dpe)(H_(2)O)]·(1,2-dpe)·7H_(2)O(3),(1,2-bixH)[Cd3(1,4-ndpaH)(1,4-ndpaH_(2))2(H_(2)O)_(2)](4),and[Cd(1,4-ndpaH_(2))(H_(2)O)]·H_(2)O(5),have been synthesized from the selfassembly reactions of 1,4-naphthalenediphosphonic acid(1,4-ndpaH4)with Cd(NO3)2·4H_(2)O by introducing auxiliary ligands with variation of rigidity,such as 4,4'-bipyridine(4,4'-bpy),1,4-bis(1-imidazolyl)benzene(1,4-bib),1,2-di(4-pyridyl)ethylene(1,2-dpe),1,3-di(4-pyridyl)propane(1,3-dpp),and bis(imidazol-1-ylmethyl)benzene(1,2-bix),respectively.Structure resolution by single-crystal X-ray diffraction reveals that compound 1 possesses a layered framework,in which the{Cd3(PO2)2}trimers made up of corner-sharing two{CdO4N2}and one{CdO6}octahedra are connected by phosphonate groups,forming a ribbon,which are cross-linked by 4,4'-bipy ligands,forming a 2D layer.Compound 2 shows a 3D open-framework structure,where chains of corner-sharing{CdO4N}trigonal bipyramids and{PO3C}tetrahedra are cross-linked by 1,4-bib and/or phosphonate groups.A 1D ladder-like chain structure is found in compound 3,where the ladder-like chains made up of corner-sharing{CdO5N}octahedra and{PO3C}tetra hedra are connected by 1,4-ndpaH_(2)^(2-).Both compounds 4 and 5 obtained by the introduction of flexible ligands during the synthesis show a 2D layered structure,which is formed by ligand crosslinking double metal chains.Interestingly,In 4,flexible 1,2-bix was singly protonated,as vip molecules,filled between layer and layer,while flexible ligand 1,3-dpp is absent in 5.Photophysical measurements indicate that compounds 1-5 show ligand-centered emissions.
文摘In order to address the current inability of screen printing to monitor printing pressure online,an online printing pressure monitoring system applied to screen printing machines was designed in this study.In this study,the consistency of printed electrodes was measured by using a confocal microscope and the pressure distribution detected by online pressure monitoring system was compared to investigate the relationship.The results demonstrated the relationship between printing pressure and the consistency of printed electrodes.As printing pressure increases,the ink layer at the corresponding position becomes thicker and that higher printing pressure enhances the consistency of the printed electrodes.The experiment confirms the feasibility of the online pressure monitoring system,which aids in predicting and controlling the consistency of printed electrodes,thereby improving their performance.
基金Funded by the Provincial Key Research and Development Program of Hebei(No.20311004D)the Foundation of Shougang Research Institute of Technology(No.2020RZ06-031)。
文摘The solidification and corrosion behavior of the Ti/B added Zn-Al-Mg alloys were experimentally investigated by means of microstructure characterization and electrochemical test.The basic calculations were carried out to predict the characteristics of the Ti-added Zn-Al-Mg alloys.The Zn-Al-Mg ingots with minor doping of Ti/B were prepared and solidified under different cooling rate,including air cooling,water quenching and furnace cooling.The scanning electron microscopy(SEM)and the X-ray diffraction method(XRD)were used to determine the microstructures and phase types of the alloy samples.It could be discovered that trace TiAl3 particles were dispersed in the Ti/B added alloy samples which provide the heterogeneous nucleation sites to refine the size of the dendrites and the eutectic microstructures.More fined microstructures with the addition of both Ti and B were obtained compared with those with the merely addition of Ti,and the water cooled alloys presented the finest microstructures due to the fastest cooling rate.It could also be noticed that with the increasing solidification rate,the percentage of the MgZn_(2) phase turned out to be higher because of the Mg_(2)Zn_(11)↔MgZn_(2) transition,which is in consistent with the results in the actual hot-dip galvanizing process.Electrochemical experiments in the previous work included methods the of the Tafel polarization test and the electrochemical impedance spectroscopy test(EIS).Results show that the quenched Zn-Al-Mg alloy with the addition of both Ti and B takes on best corrosion resistance.Consequently,the addition of certain amount of Ti/B elements and the appropriate elevation of the cooling rate will be the practicable approaches to optimize the microstructure and the corrosion resistance of the Zn-Al-Mg coatings in the actual galvanizing process.
基金supported by the Graduate Student Innovation Fund of Xi’an Shiyou University(No.YCS21211087).
文摘This paper presents a photonic crystal(PhC)line-defect slow-light waveguide modified by resonant rings.We introduce resonant rings into the line defect,constructing a slow-light waveguide with high normalized delay bandwidth product(NDBP)and low group velocity dispersion(GVD).We simulate,analyze,and optimize the structural parameters of this slow-light waveguide using the finite difference time domain(FDTD)method,theoretically achieving a maximum group index of 3.7,maximum bandwidth of 15.6 nm,and maximum NDBP of 0.4416 for slow-light effect.The resonant ring-modified PhC slow-light waveguide designed in this paper exhibits GVD lower than the order of 10^(−20)s^(2)/m over a normalized frequency range from 0.3554 to 0.4175.This study is expected to provide theoretical references for the study of slow-light buffering devices based on PhCs with high NDBP values.
基金Supported by the Capital’s Funds for Health Improvement and Research:Clinical Study on Yiqi Liangxue Shengji Prescription for Improving Cardiac Function after Myocardial Ischemia Reperfusion Injury in Patients with Acute Myocardial Infarction(CFH 2020-4-4204)Beijing University of Traditional Chinese Medicine Qihuang Yingcai·Excellent Young Science and Technology Talent Cultivation Program(K2023A03)Beijing University of Traditional Chinese Medicine Dongfang Hospital High-level Capacity Building Project"Zhuoyuan"Project National Talent Precision Cultivation Program(DFRCZY-2024GJRC012)。
文摘OBJECTIVE:To evaluate the effect of Yiqi Liangxue Shengji prescription(益气凉血生肌方,YQLXSJ)on cardiac function and outcomes in acute myocardial infarction(AMI)patients with myocardial ischemiareperfusion injury(MIRI)and to determine its clinical efficacy.METHODS:This prospective,randomized,double-blind,placebo-controlled trial enrolled hospitalized patients with AMI who underwent percutaneous coronary intervention and experienced MIRI either intraoperatively or postoperatively.Participants were randomly allocated to the treatment group,which received YQLXSJ,or the control group,which received a placebo,concurrent with standard Western Medicine therapy.The intervention period lasted 8 weeks.The primary outcome measure was left ventricular ejection fraction(LVEF),determined by echocardiography.Secondary outcomes included Nterminal pro brain natriuretic peptide(NT-pro BNP)and cardiac troponin I(cTnI)levels,left ventricular internal diameter,major adverse cardiovascular events(MACE),angina pectoris scores,and Chinese medicine evidence scores.RESULTS:Following 8 weeks of intervention,the treatment group demonstrated a significant increase in LVEF and a marked reduction in NT-pro BNP when compared to the control group.There was also a significant decrease in peak cTnI levels,Chinese medicine evidence scores,and angina pectoris scores.The control group's left ventricular end-systolic diameter(LVESD)significantly increased compared to baseline after 8 weeks(P<0.05),whereas the treatment group's LVESD showed no significant change from baseline(P>0.05).Although the treatment group showed a downward trend in MACE incidence compared to the control group,this difference was not statistically significant(P>0.05).CONCLUSIONS:This study demonstrated that the addition of YQLXSJ to standard therapy can improve cardiac function and alleviate clinical symptoms in AMI patients with MIRI,and also showed a potential to mitigate the incidence of MACE.Furthermore,YQLXSJ displayed a favorable safety profile in clinical application.
基金funded by the National Natural Science Foundation of China(41704031,42374040)the Natural Science Foundation of Jiangxi Science and Technology Department(20232BAB203073)the Key Laboratory of Mine Environmental Monitoring and Improving around Poyang Lake,Ministry of Natural Resources(MEMI-2021-2022-29).
文摘The March 11,2011,MW9.0 Tohoku-Oki earthquake,in Japan,caused rapid strain release near the epicenter,while the Boso Peninsula,located farther away,experienced stress redistribution,leading to changes in the recurrence interval of slow slip events(SSEs)and regional strain.This study focuses on three detected post-2011 Boso SSEs,utilizing a segmented model displacement time series measured by Global Navigation Satellite System(GNSS)to calculate velocity and strain rate fields for eight periods before,during,and after the SSEs.Results show that the 2011 earthquake and the three SSEs significantly alter the velocity field in the Boso region,with SSE velocities predominantly oriented southeast,reaching maximum values of 26.9 cm/a,10.6 cm/a,and 38.5 cm/adnearly opposite to non-SSE periods.After the third SSE,the velocity field nearly returns to its pre-earthquake state,with a maximum of 1.8 cm/a.The maximum shear strain rates during the three SSEs are 25.88×10^(-7) a^(-1),11.38×10^(-7) a^(-1),and 29.02×10^(-7) a^(-1)(i.e.,per annum),significantly higher than those during non-slow slip periods,with principal strain rates following a similar pattern.The spatial distribution of strain rates during the SSEs indicates greater deformation compared to the non-slip periods,dominated by northwest-southeast extension and southwest-northeast compression.Spatiotemporal analysis reveals a strong correlation between seismic frequency and strain rate during the SSEs,with time correlation coefficients of 0.85,0.88,and 0.9.Although larger accumulated strain results in stronger strain release during the latter two SSEs,not all strain is fully released,suggesting that earthquake swarms accompanying the SSEs may contribute to the partial release of unreleased strain.This study,through the analysis of GNSS data,evaluates the spatiotemporal distribution of strain fields during periodic SSEs,contributing to further research on strain accumulation and release,and aiding in the analysis of this regional seismic activity.