Cyan-emitting Ca_(9)NaGd_(2/3)(PO_(4))_(7):Eu^(2+)phosphors were synthesized via high temperature solid-state route.X-ray powder diffraction(XRD)and scanning electron microscopy(SEM)were used to verify the phase and m...Cyan-emitting Ca_(9)NaGd_(2/3)(PO_(4))_(7):Eu^(2+)phosphors were synthesized via high temperature solid-state route.X-ray powder diffraction(XRD)and scanning electron microscopy(SEM)were used to verify the phase and morphology of the Ca_(9)NaGd_(2/3)(PO_(4))_(7):Eu^(2+)(CNGP:Eu^(2+))phosphors.The as-obtained phosphor exhibits a broad excitation band of 250-420 nm,which is near the ultraviolet region.An intense asymmetric cyan emission at 496 nm corresponds to the 5 d-4 f transition of Eu^(2+).The multiplesite luminescent properties of Eu^(2+)ions in CNGP benefit from versatile structure ofβ-Ca3(PO4)2 compounds.The effective energy transfer distance is 5.46 nm(through the spectral overlap calculation),validating that the resonant energy migration type is via dipole-dipole interaction mechanism.Compared to the initial one at room temperature,the luminescent intensity of CNGP:Eu^(2+)phosphor can maintain 77%as it is heated up to 420 K.A white light-emitting diode(WLED)with excellent luminesce nt properties was successfully fabricated.Moreover,the CIE chromaticity coordinates of fabricated WLED driven by changing current just change slightly.展开更多
In this work,the effect of a magnetic island on Alfvén waves is studied.A physical model is established wherein Alfvén waves propagate in the presence of a magnetic island in a cylindrical geometry.The struc...In this work,the effect of a magnetic island on Alfvén waves is studied.A physical model is established wherein Alfvén waves propagate in the presence of a magnetic island in a cylindrical geometry.The structure of the Alfvén wave continuum is calculated by considering only the coupling caused by the periodicity in the helical angle of the magnetic island.The results show that the magnetic island can induce an upshift in the Alfvén continuum.Moreover,the coupling between different branches of the continuous spectrum becomes more significant with increasing continuum mode numbers near the boundary of the magnetic island.展开更多
Seismic facies analysis plays important roles in geological research,especially in sedimentary environment identification.Traditional method is mainly based on seismic waveform or attributes of a single seismic gather...Seismic facies analysis plays important roles in geological research,especially in sedimentary environment identification.Traditional method is mainly based on seismic waveform or attributes of a single seismic gather to classify the seismic facies.Ignoring the correlation between adjacent seismic gathers leads to poor lateral continuities in generated facies map,which cannot fit the sedimentary characteristics well.In fact,according to sedimentology theory,the horizontal continuities of the stratum can be utilized as priori information to provide more information for waveform classification.Therefore,we develop an unsupervised method for pre-stack seismic facies analysis,which is constrained by spatial continuity.The proposed method establishes a probabilistic model to characterize the correlation between neighboring reflection elements.Subsequently,this correlation is used as a regularization term to modify the objective function of the clustering algorithm,allowing the mode assignment of reflective elements to be influenced by the labels of their neighbors.Test on synthetic data confirms that,compared with traditional seismic facies analysis methods,the facies maps generated by the proposed method have more continuous and homogeneous textures,and less uncertainty on the boundary.The test on actual seismic data further confirms that the proposed method can describe more details of the distribution of lithological bodies of interest.The proposed method is an effective tool for pre-stack seismic facies analysis.展开更多
Background:Pulmonary blastoma(PB)is a rare subtype of lung cancer.Currently,the underlying pathogenesis mechanisms of PB have not been fully illustrated,and the therapeutic approach for this entity is limited.Methods:...Background:Pulmonary blastoma(PB)is a rare subtype of lung cancer.Currently,the underlying pathogenesis mechanisms of PB have not been fully illustrated,and the therapeutic approach for this entity is limited.Methods:Whole-exome sequencing(WES),RNA sequencing,and DNA methylation profiling are applied to seven PB patients.Multi-omics data of pulmonary sarcomatoid carcinoma(PSC)and pituitary blastoma(PitB)from previous studies are invoked to illuminate the associations among PB and these malignacies.Results:We portray the genomic alteration spectrum of PB and find that DICER1 is with the highest alteration rate(86%).We uncover that DICER1 alterations,Wnt signaling pathway dysregulation and IGF2 imprinting dysregulation are the potential pathogenesis mechanisms of PB.Moreover,we reveal that the integrated molecular features of PB are distinct from PSC,and the molecular characteristics of PB are more similar to PitB than to PSC.Pancancer analysis show that the tumor mutation burden(TMB)and leukocyte fraction(LF)of PB are low,while some cases are positive for PD-L1 or have CD8-positive focal areas,implying the potential applicability of immunotherapy in selected PB patients.Conclusion:This study depicts the integrated molecular characteristics of PB and offers novel insights into the pathogenesis and therapeutic strategies of PB.展开更多
Various investigations have been conducted to analyze the water-coverage area of the Aral Sea and the Aral Sea Basin(ASB). However, the investigations incorporated considerable uncertainty and the used water indices h...Various investigations have been conducted to analyze the water-coverage area of the Aral Sea and the Aral Sea Basin(ASB). However, the investigations incorporated considerable uncertainty and the used water indices had misclassification problem, which made different research groups present different results. Thus we first ascertain the boundaries of the ASB, the Syr and Amu river basins as well as their upper, middle and lower reaches. Then a four-band index for both liquid and solid water(ILSW) is proposed to address the misclassification problems of the classic water indices. ILSW is calculated by using the reflectance values of the green, red, near infrared, and thermal infrared bands, which combines the normalized difference water index(NDWI) and land surface temperature(LST) together. Validation results show that the ILSW water index has the highest accuracy by far in the Aral Sea Basin. Our results indicate that annual average decline of the water-coverage area was 963 km^(2) in the southern Aral Sea, whereas the northern Aral Sea has experienced little change. In the meanwhile, permanent ice and snow in upper reach of ASB has retreated considerably. Annual retreating rates of the permanent ice and snow were respectively 6233and 3841 km^(2) in upper reaches of Amu river basin(UARB) and Syr river basin(USRB). One of major reasons is that climate has become warmer in ASB. The climate change has caused serious water deficit problem. The water deficit had an increasing trend since the 1990s and its increasing rates was 3.778 billion m^(3) yearly on average. The total water deficit was 76.967 billion m^(3) on average in the whole area of ASB in the 2010s. However, up reaches of Syr river basin(USRB), a component area of ASB, had water surplus of 25.461 billion m^(3). These conclusions are useful for setting out a sustainable development strategy in ASB.展开更多
The effects of concentration and sonication on the liquid crystalline phases of collagen were investigated by several methods,especially by the atomic force microscopy(AFM).The X-ray diffraction(XRD)results revealed t...The effects of concentration and sonication on the liquid crystalline phases of collagen were investigated by several methods,especially by the atomic force microscopy(AFM).The X-ray diffraction(XRD)results revealed that the triple-helical structure of the collagen was nearly unchanged after sonication.Moreover,the differential scanning calorimetry(DSC)examinations indicated that the thermal stability of the sonicated collagen was close to that of native collagen.The AFM observations showed that collagen with a concentration of 60 mg/mL had more ordered arrays compared to that of 30 mg/mL when both samples were treated by sonication.Furthermore,the 60 mg/mL collagen solution without sonication could still form pre-cholesteric patterns,while the liquid phase could not be observed for the 30 mg/mL collagen solution under the same conditions.Generally,AFM was an effective tool for the study of the liquid crystalline phases of collagen.展开更多
基金Project supported by Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications(2019XGJSKFJJ01)the Construction Program of the key discipline in Hunan Province+4 种基金the Projects of the Education Department of Hunan Province(18A465)Science and Technology Plan Project of Chenzhou City(jsyf2017014)Natural Science Foundation of Shandong Province(ZR2018LB002)Key Research and Development Project of Shandong Province(2019GGX102081)Key Research and Development Project of Jining(2019ZDGH026)。
文摘Cyan-emitting Ca_(9)NaGd_(2/3)(PO_(4))_(7):Eu^(2+)phosphors were synthesized via high temperature solid-state route.X-ray powder diffraction(XRD)and scanning electron microscopy(SEM)were used to verify the phase and morphology of the Ca_(9)NaGd_(2/3)(PO_(4))_(7):Eu^(2+)(CNGP:Eu^(2+))phosphors.The as-obtained phosphor exhibits a broad excitation band of 250-420 nm,which is near the ultraviolet region.An intense asymmetric cyan emission at 496 nm corresponds to the 5 d-4 f transition of Eu^(2+).The multiplesite luminescent properties of Eu^(2+)ions in CNGP benefit from versatile structure ofβ-Ca3(PO4)2 compounds.The effective energy transfer distance is 5.46 nm(through the spectral overlap calculation),validating that the resonant energy migration type is via dipole-dipole interaction mechanism.Compared to the initial one at room temperature,the luminescent intensity of CNGP:Eu^(2+)phosphor can maintain 77%as it is heated up to 420 K.A white light-emitting diode(WLED)with excellent luminesce nt properties was successfully fabricated.Moreover,the CIE chromaticity coordinates of fabricated WLED driven by changing current just change slightly.
基金supported by the ITER Project of Ministry of Science and Technology(No.2022YFE03080002)National Natural Science Foundation of China(Nos.11605088 and 12005100)+5 种基金the Key Scientific Research Program of Education Department of Hunan Province(Nos.20A417 and 20A439)the National Magnetic Confinement Fusion Science Program of China(No.2015GB110002)the Hunan Provincial Natural Science Foundation of China(No.2017JJ3268)the International Cooperation Base Project of Hunan Province of China(No.2018WK4009)the Key Laboratory of Magnetic Confinement Nuclear Fusion Research in Hengyang(No.2018KJ108)the PhD Start-Up Fund of University of South China(No.2017XQD08)。
文摘In this work,the effect of a magnetic island on Alfvén waves is studied.A physical model is established wherein Alfvén waves propagate in the presence of a magnetic island in a cylindrical geometry.The structure of the Alfvén wave continuum is calculated by considering only the coupling caused by the periodicity in the helical angle of the magnetic island.The results show that the magnetic island can induce an upshift in the Alfvén continuum.Moreover,the coupling between different branches of the continuous spectrum becomes more significant with increasing continuum mode numbers near the boundary of the magnetic island.
文摘Seismic facies analysis plays important roles in geological research,especially in sedimentary environment identification.Traditional method is mainly based on seismic waveform or attributes of a single seismic gather to classify the seismic facies.Ignoring the correlation between adjacent seismic gathers leads to poor lateral continuities in generated facies map,which cannot fit the sedimentary characteristics well.In fact,according to sedimentology theory,the horizontal continuities of the stratum can be utilized as priori information to provide more information for waveform classification.Therefore,we develop an unsupervised method for pre-stack seismic facies analysis,which is constrained by spatial continuity.The proposed method establishes a probabilistic model to characterize the correlation between neighboring reflection elements.Subsequently,this correlation is used as a regularization term to modify the objective function of the clustering algorithm,allowing the mode assignment of reflective elements to be influenced by the labels of their neighbors.Test on synthetic data confirms that,compared with traditional seismic facies analysis methods,the facies maps generated by the proposed method have more continuous and homogeneous textures,and less uncertainty on the boundary.The test on actual seismic data further confirms that the proposed method can describe more details of the distribution of lithological bodies of interest.The proposed method is an effective tool for pre-stack seismic facies analysis.
基金supported by National Natural Sciences Foundation(grant number:82203827).
文摘Background:Pulmonary blastoma(PB)is a rare subtype of lung cancer.Currently,the underlying pathogenesis mechanisms of PB have not been fully illustrated,and the therapeutic approach for this entity is limited.Methods:Whole-exome sequencing(WES),RNA sequencing,and DNA methylation profiling are applied to seven PB patients.Multi-omics data of pulmonary sarcomatoid carcinoma(PSC)and pituitary blastoma(PitB)from previous studies are invoked to illuminate the associations among PB and these malignacies.Results:We portray the genomic alteration spectrum of PB and find that DICER1 is with the highest alteration rate(86%).We uncover that DICER1 alterations,Wnt signaling pathway dysregulation and IGF2 imprinting dysregulation are the potential pathogenesis mechanisms of PB.Moreover,we reveal that the integrated molecular features of PB are distinct from PSC,and the molecular characteristics of PB are more similar to PitB than to PSC.Pancancer analysis show that the tumor mutation burden(TMB)and leukocyte fraction(LF)of PB are low,while some cases are positive for PD-L1 or have CD8-positive focal areas,implying the potential applicability of immunotherapy in selected PB patients.Conclusion:This study depicts the integrated molecular characteristics of PB and offers novel insights into the pathogenesis and therapeutic strategies of PB.
基金supported by the Key Program of National Natural Science Foundation of China(Grant No.42230708)the Strategic Priority Research Program of the Chinese Academy of Sciences,Pan-Third Pole Environment Study for a Green Silk Road(Grant No.XDA20060303)the K.C.Wong Education Foundation(Grant No.GJTD-2020-14)。
文摘Various investigations have been conducted to analyze the water-coverage area of the Aral Sea and the Aral Sea Basin(ASB). However, the investigations incorporated considerable uncertainty and the used water indices had misclassification problem, which made different research groups present different results. Thus we first ascertain the boundaries of the ASB, the Syr and Amu river basins as well as their upper, middle and lower reaches. Then a four-band index for both liquid and solid water(ILSW) is proposed to address the misclassification problems of the classic water indices. ILSW is calculated by using the reflectance values of the green, red, near infrared, and thermal infrared bands, which combines the normalized difference water index(NDWI) and land surface temperature(LST) together. Validation results show that the ILSW water index has the highest accuracy by far in the Aral Sea Basin. Our results indicate that annual average decline of the water-coverage area was 963 km^(2) in the southern Aral Sea, whereas the northern Aral Sea has experienced little change. In the meanwhile, permanent ice and snow in upper reach of ASB has retreated considerably. Annual retreating rates of the permanent ice and snow were respectively 6233and 3841 km^(2) in upper reaches of Amu river basin(UARB) and Syr river basin(USRB). One of major reasons is that climate has become warmer in ASB. The climate change has caused serious water deficit problem. The water deficit had an increasing trend since the 1990s and its increasing rates was 3.778 billion m^(3) yearly on average. The total water deficit was 76.967 billion m^(3) on average in the whole area of ASB in the 2010s. However, up reaches of Syr river basin(USRB), a component area of ASB, had water surplus of 25.461 billion m^(3). These conclusions are useful for setting out a sustainable development strategy in ASB.
基金support from the National Natural Science Foundation of China (Grant No.21306024)the Natural Science Foundation of Fujian Province (Grant No.2016J01208)the Foundation of Distinguished Young Scholars of Fujian Agriculture and Forestry University (Grant No.XJQ201212).
文摘The effects of concentration and sonication on the liquid crystalline phases of collagen were investigated by several methods,especially by the atomic force microscopy(AFM).The X-ray diffraction(XRD)results revealed that the triple-helical structure of the collagen was nearly unchanged after sonication.Moreover,the differential scanning calorimetry(DSC)examinations indicated that the thermal stability of the sonicated collagen was close to that of native collagen.The AFM observations showed that collagen with a concentration of 60 mg/mL had more ordered arrays compared to that of 30 mg/mL when both samples were treated by sonication.Furthermore,the 60 mg/mL collagen solution without sonication could still form pre-cholesteric patterns,while the liquid phase could not be observed for the 30 mg/mL collagen solution under the same conditions.Generally,AFM was an effective tool for the study of the liquid crystalline phases of collagen.
