Global coral reef ecosystems have been severely degraded due to the combined effects of climate change and human activities.Changes in the seawater carbonate system of coral reef ecosystems can reflect their status an...Global coral reef ecosystems have been severely degraded due to the combined effects of climate change and human activities.Changes in the seawater carbonate system of coral reef ecosystems can reflect their status and their responses to the impacts of climate change and human activities.Winter and summer surveys in 2019 found that the ecological community of the Luhuitou coral reef flat was dominated by macroalgae and corals,respectively,contrasting with the conditions 10 years ago.The Luhuitou fringing reefs were sources of atmospheric CO_(2) in both seasons.In winter,the daily variation range of dissolved inorganic carbon(DIC)in Luhuitou coral reefs was up to 450μmol/kg,while that of total alkalinity(TA)was only 68μmol/kg.This indicated that the organic production was significantly higher than the calcification process during this period.The TA/DIC was approximately 0.15,which was less than half of that in healthy coral reefs;hence,photosynthesis-respiration processes were the most important factors controlling daily changes in the seawater carbonate system.The net community production(NCP)of the Luhuitou coral reef ecosystem in winter was as high as 47.65 mmol C/(m^(2)·h).While the net community calcification(NCC)was approximately 3.35 and-4.15 mmol CaCO_(3)/(m^(2)·h)during the daytime and nighttime respectively.Therefore,the NCC for the entire day was-21.9 mmol CaCO_(3)/(m^(2)·d),indicating a net autotrophic dissolved state.In summer,the acidification was enhanced by thunderstorms and heavy rain with the highest seawater partial pressure of CO_(2)(p CO_(2))and lowest pH T.Over the past 10 years,the increase rate of seawater p CO_(2) in Luhuitou reef was approximately 13.3μatm/a***,six times that of the open ocean,while the decrease rate of pH was approximately 0.0083/a,being five times that of the global ocean.These findings underscore the importance of protecting and restoring Luhuitou fringing reef,as well as similar reefs worldwide.展开更多
In order to address environmental pollution and resource depletion caused by traditional power generation,this paper proposes an adaptive iterative dynamic-balance optimization algorithm that integrates the Improved D...In order to address environmental pollution and resource depletion caused by traditional power generation,this paper proposes an adaptive iterative dynamic-balance optimization algorithm that integrates the Improved Dung Beetle Optimizer(IDBO)with VariationalMode Decomposition(VMD).The IDBO-VMD method is designed to enhance the accuracy and efficiency of wind-speed time-series decomposition and to effectively smooth photovoltaic power fluctuations.This study innovatively improves the traditional variational mode decomposition(VMD)algorithm,and significantly improves the accuracy and adaptive ability of signal decomposition by IDBO selfoptimization of key parameters K and a.On this basis,Fourier transform technology is used to define the boundary point between high frequency and low frequency signals,and a targeted energy distribution strategy is proposed:high frequency fluctuations are allocated to supercapacitors to quickly respond to transient power fluctuations;Lowfrequency components are distributed to lead-carbon batteries,optimizing long-term energy storage and scheduling efficiency.This strategy effectively improves the response speed and stability of the energy storage system.The experimental results demonstrate that the IDBO-VMD algorithm markedly outperforms traditional methods in both decomposition accuracy and computational efficiency.Specifically,it effectively reduces the charge–discharge frequency of the battery,prolongs battery life,and optimizes the operating ranges of the state-of-charge(SOC)for both leadcarbon batteries and supercapacitors.In addition,the energy management strategy based on the algorithm not only improves the overall energy utilization efficiency of the system,but also shows excellent performance in the dynamic management and intelligent scheduling of renewable energy generation.展开更多
Diabetes mellitus represents a major global health issue,driving the need for noninvasive alternatives to traditional blood glucose monitoring methods.Recent advancements in wearable technology have introduced skin-in...Diabetes mellitus represents a major global health issue,driving the need for noninvasive alternatives to traditional blood glucose monitoring methods.Recent advancements in wearable technology have introduced skin-interfaced biosensors capable of analyzing sweat and skin biomarkers,providing innovative solutions for diabetes diagnosis and monitoring.This review comprehensively discusses the current developments in noninvasive wearable biosensors,emphasizing simultaneous detection of biochemical biomarkers(such as glucose,cortisol,lactate,branched-chain amino acids,and cytokines)and physiological signals(including heart rate,blood pressure,and sweat rate)for accurate,personalized diabetes management.We explore innovations in multimodal sensor design,materials science,biorecognition elements,and integration techniques,highlighting the importance of advanced data analytics,artificial intelligence-driven predictive algorithms,and closed-loop therapeutic systems.Additionally,the review addresses ongoing challenges in biomarker validation,sensor stability,user compliance,data privacy,and regulatory considerations.A holistic,multimodal approach enabled by these next-generation wearable biosensors holds significant potential for improving patient outcomes and facilitating proactive healthcare interventions in diabetes management.展开更多
Background:To preliminary the feasibility and the potential mechanism of classic ancient prescription of Chinese medicine Danggui Longhui pill in the treatment of COVID-19 based on network pharmacology.Methods:The act...Background:To preliminary the feasibility and the potential mechanism of classic ancient prescription of Chinese medicine Danggui Longhui pill in the treatment of COVID-19 based on network pharmacology.Methods:The active constituents and acting targets of classic ancient prescription of Chinese medicine Danggui Longhui pill were collected and screen out by Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platformand Genecard databases.Cytoscape-v3.7.2 software and Search Tool for the Retrieval of Interacting Genes databases were used to construct and analyze networks and protein-protein interaction network.The R programming language software combined with Bioconductor were used to analyze gene function(the gene oncology)and gene pathway(Kyoto Encyclopedia of Genes and Genomes)enrichment of the targets.Results:Seventy-three active constituents of classic ancient prescription of Chinese medicine classic ancient prescription of Chinese medicine Danggui Longhui pill played its effect on 48 targets through 83 signal pathway were effected,including advanced glycation end products/receptor for advanced glycation end products,interleukin-17,tumorecrosis factor,NOD-like receptor and cytokine-cytokine receptor interaction.Conclusion:Classic ancient prescription of Chinese medicine Danggui Longhui pill has certain feasibility in the treatment of COVID-19.To predict the potential mechanism of classic ancient prescription of Chinese medicine Danggui Longhui pill in the treatment of COVID-19 may be related to the regulate inflammation and immune system.展开更多
在描述气泡聚并的碰撞筒(Collision Tube)理论中,气泡沿碰撞方向的横截面积及其所携带的湍动能是决定碰撞速率的两个关键点。在气液鼓泡流动中,随着气泡体积增大,气泡形状由球形向椭球形、球帽形转变,其相应的投影面积也发生变化。由于...在描述气泡聚并的碰撞筒(Collision Tube)理论中,气泡沿碰撞方向的横截面积及其所携带的湍动能是决定碰撞速率的两个关键点。在气液鼓泡流动中,随着气泡体积增大,气泡形状由球形向椭球形、球帽形转变,其相应的投影面积也发生变化。由于气泡对液相的强烈作用,液相湍流中剪切湍流和由气泡尾涡诱导的湍流涡漩二者共存,并且在不同的时空范围内对即将发生碰撞的气泡所携带的湍动能产生影响。针对Prince and Blanch聚并模型中的球形气泡假定和剪切湍流作用,本研究建立了考虑气泡形状和气泡诱导湍流的气泡聚并过程动力学模型,并基于群体平衡模型进行了模拟。研究结果表明,在气泡聚并模型中考虑气泡形状变化、气泡诱导湍流和剪切湍流的共同作用,能够准确捕捉气液鼓泡流动中气泡的尺寸分布特征,并且能够进一步影响气液两相的动力学特性预测结果。展开更多
Phantom limb pain(PLP)is not only a physical pain experience but also poses a significant challenge to mental health and quality of life.Currently,the mechanism of PLP treatment is still unclear,and there are many met...Phantom limb pain(PLP)is not only a physical pain experience but also poses a significant challenge to mental health and quality of life.Currently,the mechanism of PLP treatment is still unclear,and there are many methods with varying effects.This article starts with the application research of extended reality technology in PLP treatment,through describing the application of its branch technologies(virtual reality,augmented reality,and mixed reality technology),to lay the foundation for subsequent research,in the hope of finding advanced and effective treatment methods,and providing a basis for future product transformation.展开更多
This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment z...This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment zone.An experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was proposed.The composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab specimens.Two methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel beams.The experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal support.In contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading process.As the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan section.When the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span section.Since GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span section.All test specimens experienced compressive failure of concrete at the mid-span section.Calculation results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support section.The proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.展开更多
Objective: The purpose of this study is to evaluate the clinicopathologic characteristics and treatment outcomes of Papillary Thyroid Carcinomas (PTC) of the isthmus and to establish an appropriate surgical strategy. ...Objective: The purpose of this study is to evaluate the clinicopathologic characteristics and treatment outcomes of Papillary Thyroid Carcinomas (PTC) of the isthmus and to establish an appropriate surgical strategy. Methods: Thirty-four patients with PTC in isthmus are managed by surgery in National Cancer Center/Cancer Hospital of Chinese Academy of Medical Sciences, Peking Union Medical College from 1985-2008. Demographic data, surgical procedures, pathological features, stages and outcomes are analyzed. Results: Seven patients were men and 27 were women. The median age was 41 years (range, 20 - 71). Twenty-five patients were treated with thyroid isthmusectomy or wide field isthmusectomy, five with hemithyroidectomy (lobectomy and isthmusectomy) and four with hemithyroidectomy and partial resection of the contralateral lobe. Twenty-eight patients had a pathologically T1 lesion (pT1);two patients had a pT2 lesion and four had a pT3 lesion. Five patients (14.7%) had papillary carcinoma detected in one of the pretracheal lymph nodes. Thirty-two patients had a solitary lesion confined to the thyroid isthmus. One patient had two lesions in the thyroid isthmus and another one had two lesions located in the thyroid isthmus and right lobe respectively. With a median follow-up of 94 months (range, 12 - 274), two patients had a recurrence and both survived after a re-operation. There was no regional lymph node or distant organ recurrences. No deaths occurred. Conclusions: Isthmusectomy or wide field isthmusectomy could be a sufficient treatment for PTC confined to the thyroid isthmus. We also recommend that pretracheal lymph node dissection be considered.展开更多
Objective and Background Early and accurate diagnosis of spinal infections,including spinal tuberculosis,is pivotal for effective treatment but remains challenging.This study aims to assess the diagnostic yield of met...Objective and Background Early and accurate diagnosis of spinal infections,including spinal tuberculosis,is pivotal for effective treatment but remains challenging.This study aims to assess the diagnostic yield of metagenomic next-generation sequencing(mNGS)compared with that of conventional microbiological tests(CMTs)in identifying pathogens associated with spinal pathologies,with a special focus on infections leading to surgical interventions.Methods We enrolled 85 patients who underwent spinal surgery,comprising 63 patients with clinically diagnosed spinal infections,including patients with spinal tuberculosis,and 22 patients with noninfectious spinal conditions.The procedures involved irrigation and debridement for persistent wound drainage,with subsequent DNA extraction from plasma and joint fluid for mNGS and CMT analysis.Results Significantly increased C-reactive protein(CRP)levels were observed in patients with infections.The mNGS approach showed greater diagnostic sensitivity(92.06%)for detecting pathogens,including Mycobacterium tuberculosis,than did CMTs(36.51%).Despite its low specificity,mNGS had considerable negative predictive value(70.59%),underscoring its utility in ruling out infections.Conclusions The mNGS offers superior sensitivity over CMTs in the diagnosis of a variety of spinal infections,notably spinal tuberculosis.This study highlights the potential of mNGS in enhancing the diagnosis of complex spinal infections,thereby informing targeted treatment strategies.展开更多
White matter hyperintensities(WMH)are very widespread in older adults and are imaging features of both cerebral small-vessel disease and white matter microstructural impairments.Recent studies have demonstrated a clos...White matter hyperintensities(WMH)are very widespread in older adults and are imaging features of both cerebral small-vessel disease and white matter microstructural impairments.Recent studies have demonstrated a close association between WMH and some common diseases in older adults,including Alzheimer's disease and hypertension.Thus,studies of WMH are important for avoiding the occurrence of these diseases and improving the health status of older adults.This review summarizes the literature relating to WMH in terms of epidemiology,clinical presentation,pathogenesis,imaging features,and therapy.It also analyzes the limitations of present studies and provides perspectives on future directions.展开更多
The corrosion resistance and mechanical properties of peak-aged AlZnMgCu alloys containing Si and Er elements were investigated with hardness test,tensile test,intergranular corrosion test,exfoliation corrosion test a...The corrosion resistance and mechanical properties of peak-aged AlZnMgCu alloys containing Si and Er elements were investigated with hardness test,tensile test,intergranular corrosion test,exfoliation corrosion test and transmission electron microscopy.The results indicate that peak-aged AlZnMgCuSiEr alloy is strengthened by co-precipitation of η′phases and nano-sized GPB-Ⅱ zones.The yield strength of the AlZnMgCu alloy is increased by 38.5 MPa and the elongation is increased by 4.5%.At the same time,the corrosion resistance of the AlZnMgCuSiEr alloy is enhanced due to the synergistic effect of Er and Si.The maximum intergranular corrosion(IGC)depth decreases from 264.2 to 9.9μm.The fundamental reason is that the co-addition of Si and Er regulates the evolution of precipitated phases in grains and at grain boundaries.展开更多
Aqueous sodium-ion batteries(ASIBs)have garnered significant attention as promising candidates for large-scale energy storage applications.This interest is primarily due to their abundant resource availability,environ...Aqueous sodium-ion batteries(ASIBs)have garnered significant attention as promising candidates for large-scale energy storage applications.This interest is primarily due to their abundant resource availability,environmental friendliness,cost-effectiveness,and high safety.However,their electrochemical performance is limited by the thermodynamic properties of water molecules,resulting in inadequate cycling stability and insufficient specific energy density.To address these challenges,this study developed a hydrogen-bond enhanced urea-glycerol eutectic electrolyte(UGE)to expand the electrochemical stability window(ESW)of the electrolyte and suppress corresponding side reactions.The eutectic component disrupts the original hydrogen bonding network in water,creating a new,enhanced network that reduces the activity of free water and forms a uniform,dense passivation layer on the anode.As a result,the optimized composition of UGE exhibits a broad ESW of up to 3 V(-1.44 to 1.6 V vs.Ag/AgCl).The Prussian blue(PB)/UGE/NaTi_(2)(PO_(4))_(3)@C full cell exhibits an exceptionally long lifespan of 10,000 cycles at 10 C.This study introduces a low-cost,ultra-long-life ASIB system,utilizing a green and economical eutectic electrolyte,which expands the use of eutectic electrolytes in aqueous batteries and opens a new research horizon for constructing efficient electrochemical energy storage and conversion.展开更多
Coupling with high-voltage oxide cathode is the key to achieve high-energy density sulfide-based all-solid-state lithium batteries.However,the complex interfacial issues including the space charge layer effect and und...Coupling with high-voltage oxide cathode is the key to achieve high-energy density sulfide-based all-solid-state lithium batteries.However,the complex interfacial issues including the space charge layer effect and undesirable side reaction between sulfide solid-state electrolytes and oxide cathode materials are the main constraints on the development of high-performance allsolid-state lithium batteries,which lead to the continuous decay of electrochemical performance.Herein,different from the complicated coating procedure,a LiPO_(2)F_(2)additive engineering was proposed to achieve high-performance all-solid-state lithium batteries.With the introduction of LiPO_(2)F_(2)additive,a protective cathode-electrolyte interphase consisting of LiPxOyFz,LiF,and Li_(3)PO_(4)could be in situ formed to improve the interfacial stability between LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)and Li_(5.5)PS_(4.5)Cl_(1.5)(LPSC).Benefiting from this,the NCM811/LPSC/Li all-solid-state lithium battery exhibited impressive cyclic stability with a capacity retention of 85.5%after 600 cycles(at 0.5 C).Diverse and comprehensive characterization,combined with finite element simulation and density functional theory calculation fully demonstrated the effective component,interfacial stabilization function and enhanced kinetic of LiPO_(2)F_(2)-derived cathode-electrolyte interphase.This work provides not only a feasible and effective method to stabilize the cathodic interface but also worthy insight into interfacial design for high-performance all-solid-state lithium batteries.展开更多
The effects of the synergistic addition of Er and Sc on the aging and interfacial segregation behaviors of alloys were systematically studied using transmission electron microscopy(TEM)and high-angle annular dark fiel...The effects of the synergistic addition of Er and Sc on the aging and interfacial segregation behaviors of alloys were systematically studied using transmission electron microscopy(TEM)and high-angle annular dark field(HAADF)imaging.The TEM results show that Al3(Sc,Zr)with a core-shell structure can act as nucleation particles forθ′to promote uniform and fine precipitation.The STEM results show that Er solute atoms were preferentially enriched inside theθ′precipitate during thermal exposure at 225℃for 150 h.However,Sc and Mn solute atoms segregated at theθ′/α-Al matrix interface were observed at 300℃.Due to the early enrichment of Er in theθ′precipitate,the slowly diffusing Sc and Mn were segregated to the interface of theθ′precipitate before the severe coarsening of theθ′precipitate,thus further stabilizing theθ′precipitate at higher temperatures.展开更多
Lithium(Li) metal anodes(LMAs) that employ three-dimensional lithiophilic frameworks are among the most promising options for constructing high-energy-density rechargeable batteries.Herein,hollow ZnS nanosheets with t...Lithium(Li) metal anodes(LMAs) that employ three-dimensional lithiophilic frameworks are among the most promising options for constructing high-energy-density rechargeable batteries.Herein,hollow ZnS nanosheets with the coating of N-doped carbon are modified on the surface of carbon cloth(NCHZS@CC) to serve as the host material for Li metal.It is revealed that the high surface area of NCHZS@CC can significantly reduce local current density and mitigate volume change during cycling.More importantly,the lithiated product of ZnS,confined within the carbon cage,facilitates the uniform deposition of Li metal on carbon fibers and promotes the formation of a stable solid electrolyte interphase enriched with Li_(2)S,thereby improving long-term performance as the cycling progresses.Consequently,the LMAs based on NCHZS@CC demonstrate an impressive cycle life beyond560 h with an ultralow overpotential of 38 mV at a current density of 5 mA cm^(-2)with a capacity of 1 mAh cm^(-2)in the symmetric cell.In addition,when matched with a high mass loading cathode of LiFePO_(4)(11.5 mg cm^(-2)),the assembled full cell displays outstanding performance,achieving 900 cycles at a rate of 2C.展开更多
This paper presents a solution for energy storage system capacity configuration and renewable energy integration in smart grids using a multi-disciplinary optimization method.The solution involves a hybrid prediction ...This paper presents a solution for energy storage system capacity configuration and renewable energy integration in smart grids using a multi-disciplinary optimization method.The solution involves a hybrid prediction framework based on an improved grey regression neural network(IGRNN),which combines grey prediction,an improved BP neural network,and multiple linear regression with a dynamic weight allocation mechanism to enhance prediction accuracy.Additionally,an improved cuckoo search(ICS)algorithm is designed to empower the neural network model,incorporating a gamma distribution disturbance factor and adaptive inertia weight to balance global exploration and local exploitation,achieving a 40%faster convergence rate.A multi-objective snake optimization algorithm is also developed to optimize economic cost,grid stability,and energy utilization efficiency using energy storage capacity as the decision variable.The experimental results,based on a 937-day load dataset from a chemical park in Jiangsu Province,show that the IGRNN model has better prediction accuracy than traditional models,with an RMSE of 11.1361,an MAE of 8.264,and an R^(2) of 96.90%.The optimized energy storage system stabilizes the daily load curve at 800 kW,reduces the peak-valley difference by 62%,and decreases grid regulation pressure by 58.3%.This research provides theoretical and practical support for energy storage planning in high renewable energy proportion grids.Future work will focus on integrating weather data and dynamic optimization strategies under policy constraints to improve system applicability in real-world scenarios.展开更多
基金Supported by the National Key Research and Development Program of China(Nos.2021YFC3100500,2022YFC3103602,2021YFF0502800)the National Natural Science Foundation of China(No.U23A2035)+3 种基金the Science and Technology Planning Project of Guangdong Province,China(No.2023B1212060047)the State Key Laboratory of Tropical Oceanography,South China Sea Institute of Oceanology,Chinese Academy of Sciences(No.LTO1919)the Visiting Fellowship Program of the State Key Laboratory of Marine Environmental Science,Xiamen University(No.MELRS1914)the Hainan Province Key R&D Program(No.ZDYF2023SHFZ131)。
文摘Global coral reef ecosystems have been severely degraded due to the combined effects of climate change and human activities.Changes in the seawater carbonate system of coral reef ecosystems can reflect their status and their responses to the impacts of climate change and human activities.Winter and summer surveys in 2019 found that the ecological community of the Luhuitou coral reef flat was dominated by macroalgae and corals,respectively,contrasting with the conditions 10 years ago.The Luhuitou fringing reefs were sources of atmospheric CO_(2) in both seasons.In winter,the daily variation range of dissolved inorganic carbon(DIC)in Luhuitou coral reefs was up to 450μmol/kg,while that of total alkalinity(TA)was only 68μmol/kg.This indicated that the organic production was significantly higher than the calcification process during this period.The TA/DIC was approximately 0.15,which was less than half of that in healthy coral reefs;hence,photosynthesis-respiration processes were the most important factors controlling daily changes in the seawater carbonate system.The net community production(NCP)of the Luhuitou coral reef ecosystem in winter was as high as 47.65 mmol C/(m^(2)·h).While the net community calcification(NCC)was approximately 3.35 and-4.15 mmol CaCO_(3)/(m^(2)·h)during the daytime and nighttime respectively.Therefore,the NCC for the entire day was-21.9 mmol CaCO_(3)/(m^(2)·d),indicating a net autotrophic dissolved state.In summer,the acidification was enhanced by thunderstorms and heavy rain with the highest seawater partial pressure of CO_(2)(p CO_(2))and lowest pH T.Over the past 10 years,the increase rate of seawater p CO_(2) in Luhuitou reef was approximately 13.3μatm/a***,six times that of the open ocean,while the decrease rate of pH was approximately 0.0083/a,being five times that of the global ocean.These findings underscore the importance of protecting and restoring Luhuitou fringing reef,as well as similar reefs worldwide.
基金funded by the Institute of Smart Energy,Huaiyin Institute of Technology,under Grant No.HIT-ISE-2024-07.
文摘In order to address environmental pollution and resource depletion caused by traditional power generation,this paper proposes an adaptive iterative dynamic-balance optimization algorithm that integrates the Improved Dung Beetle Optimizer(IDBO)with VariationalMode Decomposition(VMD).The IDBO-VMD method is designed to enhance the accuracy and efficiency of wind-speed time-series decomposition and to effectively smooth photovoltaic power fluctuations.This study innovatively improves the traditional variational mode decomposition(VMD)algorithm,and significantly improves the accuracy and adaptive ability of signal decomposition by IDBO selfoptimization of key parameters K and a.On this basis,Fourier transform technology is used to define the boundary point between high frequency and low frequency signals,and a targeted energy distribution strategy is proposed:high frequency fluctuations are allocated to supercapacitors to quickly respond to transient power fluctuations;Lowfrequency components are distributed to lead-carbon batteries,optimizing long-term energy storage and scheduling efficiency.This strategy effectively improves the response speed and stability of the energy storage system.The experimental results demonstrate that the IDBO-VMD algorithm markedly outperforms traditional methods in both decomposition accuracy and computational efficiency.Specifically,it effectively reduces the charge–discharge frequency of the battery,prolongs battery life,and optimizes the operating ranges of the state-of-charge(SOC)for both leadcarbon batteries and supercapacitors.In addition,the energy management strategy based on the algorithm not only improves the overall energy utilization efficiency of the system,but also shows excellent performance in the dynamic management and intelligent scheduling of renewable energy generation.
文摘Diabetes mellitus represents a major global health issue,driving the need for noninvasive alternatives to traditional blood glucose monitoring methods.Recent advancements in wearable technology have introduced skin-interfaced biosensors capable of analyzing sweat and skin biomarkers,providing innovative solutions for diabetes diagnosis and monitoring.This review comprehensively discusses the current developments in noninvasive wearable biosensors,emphasizing simultaneous detection of biochemical biomarkers(such as glucose,cortisol,lactate,branched-chain amino acids,and cytokines)and physiological signals(including heart rate,blood pressure,and sweat rate)for accurate,personalized diabetes management.We explore innovations in multimodal sensor design,materials science,biorecognition elements,and integration techniques,highlighting the importance of advanced data analytics,artificial intelligence-driven predictive algorithms,and closed-loop therapeutic systems.Additionally,the review addresses ongoing challenges in biomarker validation,sensor stability,user compliance,data privacy,and regulatory considerations.A holistic,multimodal approach enabled by these next-generation wearable biosensors holds significant potential for improving patient outcomes and facilitating proactive healthcare interventions in diabetes management.
基金supported by Scientific Research Youth Fund of Health Department of Fujian Province(2018-1-90)Educational and Scientific Research Fund for Young and Middle-aged Teachers of Fujian Province(JAT191299)Ministry of Education Key Laboratory for Analytical Science of Food Safety and Biology,Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety(FS1809).
文摘Background:To preliminary the feasibility and the potential mechanism of classic ancient prescription of Chinese medicine Danggui Longhui pill in the treatment of COVID-19 based on network pharmacology.Methods:The active constituents and acting targets of classic ancient prescription of Chinese medicine Danggui Longhui pill were collected and screen out by Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platformand Genecard databases.Cytoscape-v3.7.2 software and Search Tool for the Retrieval of Interacting Genes databases were used to construct and analyze networks and protein-protein interaction network.The R programming language software combined with Bioconductor were used to analyze gene function(the gene oncology)and gene pathway(Kyoto Encyclopedia of Genes and Genomes)enrichment of the targets.Results:Seventy-three active constituents of classic ancient prescription of Chinese medicine classic ancient prescription of Chinese medicine Danggui Longhui pill played its effect on 48 targets through 83 signal pathway were effected,including advanced glycation end products/receptor for advanced glycation end products,interleukin-17,tumorecrosis factor,NOD-like receptor and cytokine-cytokine receptor interaction.Conclusion:Classic ancient prescription of Chinese medicine Danggui Longhui pill has certain feasibility in the treatment of COVID-19.To predict the potential mechanism of classic ancient prescription of Chinese medicine Danggui Longhui pill in the treatment of COVID-19 may be related to the regulate inflammation and immune system.
文摘在描述气泡聚并的碰撞筒(Collision Tube)理论中,气泡沿碰撞方向的横截面积及其所携带的湍动能是决定碰撞速率的两个关键点。在气液鼓泡流动中,随着气泡体积增大,气泡形状由球形向椭球形、球帽形转变,其相应的投影面积也发生变化。由于气泡对液相的强烈作用,液相湍流中剪切湍流和由气泡尾涡诱导的湍流涡漩二者共存,并且在不同的时空范围内对即将发生碰撞的气泡所携带的湍动能产生影响。针对Prince and Blanch聚并模型中的球形气泡假定和剪切湍流作用,本研究建立了考虑气泡形状和气泡诱导湍流的气泡聚并过程动力学模型,并基于群体平衡模型进行了模拟。研究结果表明,在气泡聚并模型中考虑气泡形状变化、气泡诱导湍流和剪切湍流的共同作用,能够准确捕捉气液鼓泡流动中气泡的尺寸分布特征,并且能够进一步影响气液两相的动力学特性预测结果。
文摘Phantom limb pain(PLP)is not only a physical pain experience but also poses a significant challenge to mental health and quality of life.Currently,the mechanism of PLP treatment is still unclear,and there are many methods with varying effects.This article starts with the application research of extended reality technology in PLP treatment,through describing the application of its branch technologies(virtual reality,augmented reality,and mixed reality technology),to lay the foundation for subsequent research,in the hope of finding advanced and effective treatment methods,and providing a basis for future product transformation.
基金supported by National Natural Science Foundation of China(Project No.51878156,received by Wen-Wei Wang) and EPC Innovation Consulting Project for Longkou Nanshan LNG Phase I Receiving Terminal(Z2000LGENT0399,received by Wen-Wei Wang and ZhaoJun Zhang).
文摘This study aimed to investigate the moment redistribution in continuous glass fiber reinforced polymer(GFRP)-concrete composite slabs caused by concrete cracking and steel bar yielding in the negative bending moment zone.An experimental bending moment redistribution test was conducted on continuous GFRP-concrete composite slabs,and a calculation method based on the conjugate beam method was proposed.The composite slabs were formed by combining GFRP profiles with a concrete layer and supported on steel beams to create two-span continuous composite slab specimens.Two methods,epoxy resin bonding,and stud connection,were used to connect the composite slabs with the steel beams.The experimental findings showed that the specimen connected with epoxy resin exhibited two moments redistribution phenomena during the loading process:concrete cracking and steel bar yielding at the internal support.In contrast,the composite slab connected with steel beams by studs exhibited only one-moment redistribution phenomenon throughout the loading process.As the concrete at the internal support cracked,the bending moment decreased in the internal support section and increased in the midspan section.When the steel bars yielded,the bending moment further decreased in the internal support section and increased in the mid-span section.Since GFRP profiles do not experience cracking,there was no significant decrease in the bending moment of the mid-span section.All test specimens experienced compressive failure of concrete at the mid-span section.Calculation results showed good agreement between the calculated and experimental values of bending moments in the mid-span section and internal support section.The proposed model can effectively predict the moment redistribution behavior of continuous GFRP-concrete composite slabs.
文摘Objective: The purpose of this study is to evaluate the clinicopathologic characteristics and treatment outcomes of Papillary Thyroid Carcinomas (PTC) of the isthmus and to establish an appropriate surgical strategy. Methods: Thirty-four patients with PTC in isthmus are managed by surgery in National Cancer Center/Cancer Hospital of Chinese Academy of Medical Sciences, Peking Union Medical College from 1985-2008. Demographic data, surgical procedures, pathological features, stages and outcomes are analyzed. Results: Seven patients were men and 27 were women. The median age was 41 years (range, 20 - 71). Twenty-five patients were treated with thyroid isthmusectomy or wide field isthmusectomy, five with hemithyroidectomy (lobectomy and isthmusectomy) and four with hemithyroidectomy and partial resection of the contralateral lobe. Twenty-eight patients had a pathologically T1 lesion (pT1);two patients had a pT2 lesion and four had a pT3 lesion. Five patients (14.7%) had papillary carcinoma detected in one of the pretracheal lymph nodes. Thirty-two patients had a solitary lesion confined to the thyroid isthmus. One patient had two lesions in the thyroid isthmus and another one had two lesions located in the thyroid isthmus and right lobe respectively. With a median follow-up of 94 months (range, 12 - 274), two patients had a recurrence and both survived after a re-operation. There was no regional lymph node or distant organ recurrences. No deaths occurred. Conclusions: Isthmusectomy or wide field isthmusectomy could be a sufficient treatment for PTC confined to the thyroid isthmus. We also recommend that pretracheal lymph node dissection be considered.
基金supported by the Hubei Provincial Natural Science Foundation of China(No.2023AFB646)Knowledge Innovation Program of Wuhan(No.2023020201010155)Educational Research Program of Huazhong University of Science and Technology(No.2022135).
文摘Objective and Background Early and accurate diagnosis of spinal infections,including spinal tuberculosis,is pivotal for effective treatment but remains challenging.This study aims to assess the diagnostic yield of metagenomic next-generation sequencing(mNGS)compared with that of conventional microbiological tests(CMTs)in identifying pathogens associated with spinal pathologies,with a special focus on infections leading to surgical interventions.Methods We enrolled 85 patients who underwent spinal surgery,comprising 63 patients with clinically diagnosed spinal infections,including patients with spinal tuberculosis,and 22 patients with noninfectious spinal conditions.The procedures involved irrigation and debridement for persistent wound drainage,with subsequent DNA extraction from plasma and joint fluid for mNGS and CMT analysis.Results Significantly increased C-reactive protein(CRP)levels were observed in patients with infections.The mNGS approach showed greater diagnostic sensitivity(92.06%)for detecting pathogens,including Mycobacterium tuberculosis,than did CMTs(36.51%).Despite its low specificity,mNGS had considerable negative predictive value(70.59%),underscoring its utility in ruling out infections.Conclusions The mNGS offers superior sensitivity over CMTs in the diagnosis of a variety of spinal infections,notably spinal tuberculosis.This study highlights the potential of mNGS in enhancing the diagnosis of complex spinal infections,thereby informing targeted treatment strategies.
基金supported by a grant from the Natural Science Foundation of Shandong Provincial,China(No.ZR2020MH328).
文摘White matter hyperintensities(WMH)are very widespread in older adults and are imaging features of both cerebral small-vessel disease and white matter microstructural impairments.Recent studies have demonstrated a close association between WMH and some common diseases in older adults,including Alzheimer's disease and hypertension.Thus,studies of WMH are important for avoiding the occurrence of these diseases and improving the health status of older adults.This review summarizes the literature relating to WMH in terms of epidemiology,clinical presentation,pathogenesis,imaging features,and therapy.It also analyzes the limitations of present studies and provides perspectives on future directions.
基金funded by the National Key Research and Development Program of China(Nos.2021YFB3700902,2021YFB3704204,and 2021YFB3704205)the Beijing Lab Project for Modern Transportation Metallic Materials and Processing Technology,China,the Jiangsu Key Laboratory for Clad Materials,China(No.BM2014006)+4 种基金the Doctor Funds of Taiyuan University of Science and Technology,China(No.20222063)the Fundamental Research Program of Shanxi Province,China(No.202303021212216)the Award Fund for Outstanding Doctors in Shanxi Province,China(No.20232045)the Scientific and Technological Innovation Programs of Higher Education Institutions in Shanxi Province,China(Nos.2022L289,and 2022L280)the Special Project for Transformation of Scientific Achievements,China(No.202204021301025)。
文摘The corrosion resistance and mechanical properties of peak-aged AlZnMgCu alloys containing Si and Er elements were investigated with hardness test,tensile test,intergranular corrosion test,exfoliation corrosion test and transmission electron microscopy.The results indicate that peak-aged AlZnMgCuSiEr alloy is strengthened by co-precipitation of η′phases and nano-sized GPB-Ⅱ zones.The yield strength of the AlZnMgCu alloy is increased by 38.5 MPa and the elongation is increased by 4.5%.At the same time,the corrosion resistance of the AlZnMgCuSiEr alloy is enhanced due to the synergistic effect of Er and Si.The maximum intergranular corrosion(IGC)depth decreases from 264.2 to 9.9μm.The fundamental reason is that the co-addition of Si and Er regulates the evolution of precipitated phases in grains and at grain boundaries.
基金support by the Department of Science&Technology of Zhejiang Province under grant No.2024C01095the Fundamental Research Funds for the Provincial Universities of Zhejiang under grant No.RF-C2022008the National Natural Science Foundation of China(NSFC)under grant Nos.U20A20253,52372235,and 22279116。
文摘Aqueous sodium-ion batteries(ASIBs)have garnered significant attention as promising candidates for large-scale energy storage applications.This interest is primarily due to their abundant resource availability,environmental friendliness,cost-effectiveness,and high safety.However,their electrochemical performance is limited by the thermodynamic properties of water molecules,resulting in inadequate cycling stability and insufficient specific energy density.To address these challenges,this study developed a hydrogen-bond enhanced urea-glycerol eutectic electrolyte(UGE)to expand the electrochemical stability window(ESW)of the electrolyte and suppress corresponding side reactions.The eutectic component disrupts the original hydrogen bonding network in water,creating a new,enhanced network that reduces the activity of free water and forms a uniform,dense passivation layer on the anode.As a result,the optimized composition of UGE exhibits a broad ESW of up to 3 V(-1.44 to 1.6 V vs.Ag/AgCl).The Prussian blue(PB)/UGE/NaTi_(2)(PO_(4))_(3)@C full cell exhibits an exceptionally long lifespan of 10,000 cycles at 10 C.This study introduces a low-cost,ultra-long-life ASIB system,utilizing a green and economical eutectic electrolyte,which expands the use of eutectic electrolytes in aqueous batteries and opens a new research horizon for constructing efficient electrochemical energy storage and conversion.
基金support by the Department of Science&Technology of Zhejiang Province under grant no.2024C01095Zhejiang Provincial Natural Science Foundation of China under grant nos.LD22E020006 and LBMHD24E020001the National Natural Science Foundation of China(NSFC)under grant nos.21972127,U20A20253,and 22279116.
文摘Coupling with high-voltage oxide cathode is the key to achieve high-energy density sulfide-based all-solid-state lithium batteries.However,the complex interfacial issues including the space charge layer effect and undesirable side reaction between sulfide solid-state electrolytes and oxide cathode materials are the main constraints on the development of high-performance allsolid-state lithium batteries,which lead to the continuous decay of electrochemical performance.Herein,different from the complicated coating procedure,a LiPO_(2)F_(2)additive engineering was proposed to achieve high-performance all-solid-state lithium batteries.With the introduction of LiPO_(2)F_(2)additive,a protective cathode-electrolyte interphase consisting of LiPxOyFz,LiF,and Li_(3)PO_(4)could be in situ formed to improve the interfacial stability between LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)and Li_(5.5)PS_(4.5)Cl_(1.5)(LPSC).Benefiting from this,the NCM811/LPSC/Li all-solid-state lithium battery exhibited impressive cyclic stability with a capacity retention of 85.5%after 600 cycles(at 0.5 C).Diverse and comprehensive characterization,combined with finite element simulation and density functional theory calculation fully demonstrated the effective component,interfacial stabilization function and enhanced kinetic of LiPO_(2)F_(2)-derived cathode-electrolyte interphase.This work provides not only a feasible and effective method to stabilize the cathodic interface but also worthy insight into interfacial design for high-performance all-solid-state lithium batteries.
基金supported by the National Key Research and Development Program of China(Nos.2021YFB3700902,2021YFB3704204,2021YFB3704205)Innovative Research Group Project of the National Natural Science Foundation of China(No.51621003)+3 种基金Beijing Natural Science Foundation,China(No.2202009)Basic Research Program of Jiangsu Province,China(No.BK20191148)Beijing Lab Project for Modern Transportation Metallic Materials and Processing Technology,ChinaJiangsu Key Laboratory for Clad Materials,China(No.BM2014006)。
文摘The effects of the synergistic addition of Er and Sc on the aging and interfacial segregation behaviors of alloys were systematically studied using transmission electron microscopy(TEM)and high-angle annular dark field(HAADF)imaging.The TEM results show that Al3(Sc,Zr)with a core-shell structure can act as nucleation particles forθ′to promote uniform and fine precipitation.The STEM results show that Er solute atoms were preferentially enriched inside theθ′precipitate during thermal exposure at 225℃for 150 h.However,Sc and Mn solute atoms segregated at theθ′/α-Al matrix interface were observed at 300℃.Due to the early enrichment of Er in theθ′precipitate,the slowly diffusing Sc and Mn were segregated to the interface of theθ′precipitate before the severe coarsening of theθ′precipitate,thus further stabilizing theθ′precipitate at higher temperatures.
基金financial supports from the National Natural Science Foundation of China(Nos.22279116 and U20A20253)the Natural Science Foundation of Zhejiang Province(Nos.LQ24E020012 and LD22E020006)Jianbing Science and Technology Project of Zhejiang Province(No.2023C01127)
文摘Lithium(Li) metal anodes(LMAs) that employ three-dimensional lithiophilic frameworks are among the most promising options for constructing high-energy-density rechargeable batteries.Herein,hollow ZnS nanosheets with the coating of N-doped carbon are modified on the surface of carbon cloth(NCHZS@CC) to serve as the host material for Li metal.It is revealed that the high surface area of NCHZS@CC can significantly reduce local current density and mitigate volume change during cycling.More importantly,the lithiated product of ZnS,confined within the carbon cage,facilitates the uniform deposition of Li metal on carbon fibers and promotes the formation of a stable solid electrolyte interphase enriched with Li_(2)S,thereby improving long-term performance as the cycling progresses.Consequently,the LMAs based on NCHZS@CC demonstrate an impressive cycle life beyond560 h with an ultralow overpotential of 38 mV at a current density of 5 mA cm^(-2)with a capacity of 1 mAh cm^(-2)in the symmetric cell.In addition,when matched with a high mass loading cathode of LiFePO_(4)(11.5 mg cm^(-2)),the assembled full cell displays outstanding performance,achieving 900 cycles at a rate of 2C.
基金funded by Huaian Hongeng Group Co.,Ltd.Relying on theproject“Researchon Key Technologies of Integrated Photovoltaic and Energy Storage Electric Vehicle Charging Stations”(Project Number:SGTYHT/23-JS-001).
文摘This paper presents a solution for energy storage system capacity configuration and renewable energy integration in smart grids using a multi-disciplinary optimization method.The solution involves a hybrid prediction framework based on an improved grey regression neural network(IGRNN),which combines grey prediction,an improved BP neural network,and multiple linear regression with a dynamic weight allocation mechanism to enhance prediction accuracy.Additionally,an improved cuckoo search(ICS)algorithm is designed to empower the neural network model,incorporating a gamma distribution disturbance factor and adaptive inertia weight to balance global exploration and local exploitation,achieving a 40%faster convergence rate.A multi-objective snake optimization algorithm is also developed to optimize economic cost,grid stability,and energy utilization efficiency using energy storage capacity as the decision variable.The experimental results,based on a 937-day load dataset from a chemical park in Jiangsu Province,show that the IGRNN model has better prediction accuracy than traditional models,with an RMSE of 11.1361,an MAE of 8.264,and an R^(2) of 96.90%.The optimized energy storage system stabilizes the daily load curve at 800 kW,reduces the peak-valley difference by 62%,and decreases grid regulation pressure by 58.3%.This research provides theoretical and practical support for energy storage planning in high renewable energy proportion grids.Future work will focus on integrating weather data and dynamic optimization strategies under policy constraints to improve system applicability in real-world scenarios.
