Synucleinopathies are neurodegenerative diseases char-acterized by accumulation of misfoldedα-synuclein(α-syn)inclusions in neuronal and/or glial cells.Despite differences in the underlying pathophysiology,synucle-i...Synucleinopathies are neurodegenerative diseases char-acterized by accumulation of misfoldedα-synuclein(α-syn)inclusions in neuronal and/or glial cells.Despite differences in the underlying pathophysiology,synucle-inopathies often are misdiagnosed,especially in early stages,due to the overlapping clinical symptoms[1].展开更多
基金supported by grants from the MSA Coalition 2017-10-007(GB)California Department of Public Health 18-10926(GB)+5 种基金The Alzheimer’s Association,The Michael J.Fox Foundation,Weston Brain Institute,and Alzheimer’s Research UK Biomarkers Across Neurodegenerative Diseases(BAND 3)17990(GB)CurePSP 665-2019-07(GB)The Michael J.Fox Foundation 18303(GB)The National Ataxia Foundation 20201551(GB and BLF),Cure Sanfilippo Foundation 20215318(GB)NIH/NIEHS ES10544(BR)generous gifts from the Karen Toffler Charitable Trust and the Binder Foundation。
文摘Synucleinopathies are neurodegenerative diseases char-acterized by accumulation of misfoldedα-synuclein(α-syn)inclusions in neuronal and/or glial cells.Despite differences in the underlying pathophysiology,synucle-inopathies often are misdiagnosed,especially in early stages,due to the overlapping clinical symptoms[1].
