CdS nanoclusters were directly synthesized in aqueous solution by using mercaptoacetic acid as the stabilizer. The results of TEM(Transmission Electron Microscopy) and ED(Electron Diffraction) show that the structures...CdS nanoclusters were directly synthesized in aqueous solution by using mercaptoacetic acid as the stabilizer. The results of TEM(Transmission Electron Microscopy) and ED(Electron Diffraction) show that the structures and aggregations of the resulting CdS nanoclusters can be affected by the molar ratio of mercaptoacetic acid and Cd 2+ ion. When the ratio was high, the resulting nanoclusters were observed as densely packed layer structure on the template. When the ratio was low, the prepared CdS nanoclusters can not form highly aggregated structure. Fluorescence spectra of the CdS nanoclusters show a strong yellow fluorescence.展开更多
目的未用药特发性癫痫(drug-naive idiopathic epilepsy,DNIE)是患者常规磁共振未见异常显示,且未经过抗癫痫药物治疗的一类癫痫。文中利用静息态功能磁共振成像(resting state functional magnetic resonance imaging,rs-f MRI)低频振...目的未用药特发性癫痫(drug-naive idiopathic epilepsy,DNIE)是患者常规磁共振未见异常显示,且未经过抗癫痫药物治疗的一类癫痫。文中利用静息态功能磁共振成像(resting state functional magnetic resonance imaging,rs-f MRI)低频振幅方法(amplitude of low frequency fluctuation,ALFF)研究DNIE脑功能的改变,探讨其与临床变量(病程)的相关性,以提高对特发性癫痫(idiopathic epilepsy,IE)病理生理机制的理解。方法收集合肥医学院附属医院2011年1月至2014年9月门诊及住院的DNIE患者25例,其中男15例、女10例;用药特发性癫痫(drug idiopathic epilepsy,DIE)34例,其中男22例、女12例。同时招募性别、年龄、教育程度及利手与未用药组相匹配的健康志愿者25例作为对照组。采用Siemens 3.0T Trio Tim MR采集静息态数据。对原始图像预处理后进行ALFF分析,对3组数据ALFF统计脑图进行统计,并分析ALFF统计脑图与病程的相关性。结果未用药组、用药组及正常对照组3组间的ALFF统计脑图存在差异。与正常对照组比较,未用药组ALFF增加的脑区位于右颞下回、右舌回及右楔状叶,ALFF降低的脑区位于右岛叶、左海马、右中脑、右额中回、左前扣带回、左扣带回中部及右顶下小叶。与用药组比较,未用药组ALFF增加的脑区位于左枕下回和双枕中回,ALFF降低的脑区位于右额下回、左岛叶、右颞上回及右额中回。未用药组右小脑后叶、左小脑扁桃体、右舌回、左眶回、左枕中回、左胼胝体、左尾状核、左额上回、左额内侧回、右楔前叶及左额中回的ALFF与病程呈正相关,右海马旁回、右颞上回、左颞上回及右中央后回的ALFF与病程呈负相关。结论 DNIE患者存在静息态脑功能变化,且与临床变量(病程)相关,可成为癫痫病理生理机制研究的新依据。展开更多
文摘CdS nanoclusters were directly synthesized in aqueous solution by using mercaptoacetic acid as the stabilizer. The results of TEM(Transmission Electron Microscopy) and ED(Electron Diffraction) show that the structures and aggregations of the resulting CdS nanoclusters can be affected by the molar ratio of mercaptoacetic acid and Cd 2+ ion. When the ratio was high, the resulting nanoclusters were observed as densely packed layer structure on the template. When the ratio was low, the prepared CdS nanoclusters can not form highly aggregated structure. Fluorescence spectra of the CdS nanoclusters show a strong yellow fluorescence.
文摘目的未用药特发性癫痫(drug-naive idiopathic epilepsy,DNIE)是患者常规磁共振未见异常显示,且未经过抗癫痫药物治疗的一类癫痫。文中利用静息态功能磁共振成像(resting state functional magnetic resonance imaging,rs-f MRI)低频振幅方法(amplitude of low frequency fluctuation,ALFF)研究DNIE脑功能的改变,探讨其与临床变量(病程)的相关性,以提高对特发性癫痫(idiopathic epilepsy,IE)病理生理机制的理解。方法收集合肥医学院附属医院2011年1月至2014年9月门诊及住院的DNIE患者25例,其中男15例、女10例;用药特发性癫痫(drug idiopathic epilepsy,DIE)34例,其中男22例、女12例。同时招募性别、年龄、教育程度及利手与未用药组相匹配的健康志愿者25例作为对照组。采用Siemens 3.0T Trio Tim MR采集静息态数据。对原始图像预处理后进行ALFF分析,对3组数据ALFF统计脑图进行统计,并分析ALFF统计脑图与病程的相关性。结果未用药组、用药组及正常对照组3组间的ALFF统计脑图存在差异。与正常对照组比较,未用药组ALFF增加的脑区位于右颞下回、右舌回及右楔状叶,ALFF降低的脑区位于右岛叶、左海马、右中脑、右额中回、左前扣带回、左扣带回中部及右顶下小叶。与用药组比较,未用药组ALFF增加的脑区位于左枕下回和双枕中回,ALFF降低的脑区位于右额下回、左岛叶、右颞上回及右额中回。未用药组右小脑后叶、左小脑扁桃体、右舌回、左眶回、左枕中回、左胼胝体、左尾状核、左额上回、左额内侧回、右楔前叶及左额中回的ALFF与病程呈正相关,右海马旁回、右颞上回、左颞上回及右中央后回的ALFF与病程呈负相关。结论 DNIE患者存在静息态脑功能变化,且与临床变量(病程)相关,可成为癫痫病理生理机制研究的新依据。
