摘要
目的:优化石榴皮总黄酮提取的超声辅助浸提工艺。方法:以总黄酮提取率为评价指标,在单因素试验的基础上,以颗粒筛目大小、提取溶剂百分数、料液比、浸提时间为影响因素考察对象,通过正交实验设计对石榴皮总黄酮提取的影响因素进行优化。结果:石榴皮总黄酮超声辅助浸提最佳工艺为颗粒大小100目、60%乙醇为提取溶剂、料液比为1:60、浸提60分钟。在此提取条件下,石榴皮总黄酮提取率为119.5 mg/g,其主要影响因素程度为料液比】浸提时间】乙醇浓度】筛目。结论:该方法简单、可靠,稳定性强,为石榴皮总黄酮的开发利用提供了实验依据。
Objective: The condition of ultrasonic assisted extraction process of total flavonoids from pome-granate peel was optimized. Methods: Considering the extraction rate of total flavonoids for the evaluation index, the size of particle screen, extraction solvent, extraction solvent percentage, solid-liquid ratio and extraction time were selected as the influencing factors based on the single factor experiment. Results: The optimal conditions are as follows: 100 mesh particle size, 60% ethanol as extraction solvent, 1:60 ratio of material to liquid, 60 minutes of extraction, and 30 minutes of ultrasonic extraction. Under this optimal extraction condition, the extraction rate of total flavonoids from pomegranate peel was 119.5 mg/g, and the degree of its main influencing factors was solid-liquid ratio >extracting time >ethanol concentration >mesh. Conclusions: The simple, reliable, and stable method would provide an experimental basis for the development and utilization of total flavonoids in pomegranate peel.
出处
《药物化学》
2020年第2期21-28,共8页
Hans Journal of Medicinal Chemistry
