摘要
卡博替尼是新型多靶点抗癌药物,现用于转移性甲状腺髓样癌和晚期肾癌的治疗,并对其他的肿瘤具有一定的临床疗效。结合国内外研究进展,本文综述卡博替尼的临床应用现状及应用前景,希望能对卡博替尼的研究及应用提供参考。
Cabozantinib is a novel multitargeted anti-tumor drug,which has been approved by FDA for the treatment of both progressive metastatic medullary thyroid cancer and advanced renal cell carcinoma,and is being investigated for various other malignancies.In this paper,we reviewed the clinical application and clinical research frontier of cabozantinib according to the recent study,wishing to provide the reference to the future research and application of cabozantinib.
作者
陆兆辉
周海嫔
Zhaohui Lu;Haipin Zhou(College of Materials&Chemical Engineering,Chuzhou University,Chuzhou Anhui)
出处
《药物化学》
2018年第3期62-66,共5页
Hans Journal of Medicinal Chemistry
基金
滁州学院科研启动基金资助项目,2015qd16。
关键词
多靶点抗癌药物
卡博替尼
临床应用
应用前景
Multitargeted Anti-Tumor Drugs
Cabozantinib
Clinical Application
Application Prospect
