摘要
多靶点酪氨酸激酶抑制剂的研究已经成为近年来抗肿瘤药物研究的新趋势。本文整合国内外相关文献,综述了近年来各课题组对不同结构的酪氨酸激酶抑制剂及抗肿瘤活性的研究进展,以期为酪氨酸激酶抑制剂的研究与开发提供参考。
The study on multi-targeted tyrosine kinase inhibitors has become a new trend in researches on antitumor drugs in recent years.In order to offer reference to the research and development of tyrosine kinase inhibitors,this review introduced the research results of tyrosine kinase inhibitors with different structures and antitumor activity by summarizing related literature,at home and abroad.
作者
刘丹
李雪
张毅
彭鹏辉
Dan Liu;Xue Li;Yi Zhang;Penghui Peng(College of Pharmaceutical and Biological Engineering,Shenyang University of Chemical Technology,Shenyang Liaoning)
出处
《药物化学》
2016年第4期42-54,共13页
Hans Journal of Medicinal Chemistry
