摘要
目的 评估连续腰穿治疗新生儿脑室内出血的疗效。方法 观察 15例脑室内出血 (IVH)患儿 ,其中8例患儿进行连续腰穿 (LP)治疗 ,7例口服乙酰唑胺治疗。治疗时间不少于 10天 ,观察时间不少于 2 0天。结果 连续LP组脑脊液 (CSF)蛋白含量及细胞计数下降程度与乙酰唑胺组比较有统计学意义 (P<0 .0 1)。连续LP组神经系统症状缓解时间较乙酰唑胺组缩短有统计学意义 (P <0 .0 5 )。未观察到局部或中枢神经系统感染征象。结论 连续LP治疗新生儿脑室内出血能安全有效地降低CSF蛋白含量及细胞数 ,并能迅速缓解神经系统症状。
Objective To evaluate the effects of serial lumbar puncture(LP) on intraventricular hemorrhage(IVI) in neonates. Methods 8 neonates with intraventricular hemorrhage (IVH) were treated by serial lumbar punctures (LP) (groupⅠ),At the same time another 7 neonates suffering the same disease were administered diamox (groupⅡ). The durations of treatment were not less than 10 days, and the durations of observation were not less than 20 days.Results The decrease of protein concentration and cells count in cerebrospinal fluids (CSF) in group Ⅰ was greater than that in group Ⅱ (P<0.01). And the relief of nerve system symptoms in group Ⅰ was rapider than that in group Ⅱ (P<0.05). No additional infection was observed in group Ⅰ.Conclusion For neonates IVH, serial LP can not only decrease the protein concentration and cells amount in CSF effectively and safely, but also relieve the symptoms of nerve system rapidly.
出处
《宁夏医学杂志》
CAS
2004年第6期350-352,共3页
Ningxia Medical Journal
关键词
新生儿
脑室内出血
腰穿
Neonate
Intraventricular hemorrhage
Lumbar puncture
