摘要
本文报告4例肾移植患者服用卡托普利(captopril)后发生的急性肾衰。停用卡托普利后,1例肾功能继续恶化,需维持血透,移植肾摘除后病理确诊为移植肾动脉狭窄;3例(4例)肾功能恢复至服药前水平,其中2例临床考虑移植肾动脉琳影正常。结合本文病例特点和文献,对移植肾动脉狭窄患者应用血管紧张素转换酶抑制剂后出现这类急性肾衰(ARF)的发生机理进行了讨论。
We report four cases of captopril-induced acute renal failure in the renal allogratft recipients with hypertension. Two of them were considered to have transplant renal artery stenosis (TRAS), while, one of them, with oral cyclosporine treatment, was proven no TRAS by renal arteriograghy. Renal function recovered in the three cases after withdrawal of captopril. However The renal function became worse in one case with severe TRAS, and dialysis was required.
出处
《北京医学》
CAS
北大核心
1993年第4期209-211,共3页
Beijing Medical Journal
