摘要
本文报告OPCA30例。其中有遗传史5例,占16.7%。遗传组平均发病年龄16.3岁,散发组平均发病年龄33.2岁,两组有显著差异。而且遗传组中发病年龄越小,病程进展越快,病情相对较重。24例行头颅CT扫描,11例头颅MRI检查均发现小脑、桥脑萎缩。本文对其临床诊断、分型、遗传等问题进行讨论,脑活素治疗对本病可能有一定疗效。
30 cases of OPCA were reporied and 5 of them had hereditary history (16.7%). The aver age age of onset in group with herdity was 16.3, while in sporadic group was 33.2. There was significant difference between the two (?) ps In hereditary group, the younger the (?) age was, the shorter the course of disease an(?) more the serious condition were. In 24 ca(?) ned by CT and 11 cases examined by MRI (?) phy lesions in cerebellum and pontine wer(?) nd. The clinical manifestation, diagnosis and (?)ping of the disease were discussed and the (?) cerebrolysin may be effective in the treatment
出处
《北京医学》
CAS
北大核心
1993年第1期14-17,共4页
Beijing Medical Journal
