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临床应用重组SARS病毒双抗原夹心诊断试剂盒的检测效果评价 被引量：1

Evaluation of the Clinical Detection Results Using Recombinant SARS Antigen-Capturing ELISA Diagnostic Kit
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摘要 It is necessary to establish a rapid and accurate diagnostic method for controlling the epidemic of severe acute respiratory syndrome (SARS). Cooperating with Henan Bioengineering Research Center, we developed a new diagnostic kit for antibodies to SARS virus based on antigen-capturing ELISA. Here we report the clinical detection results obtained from several hospitals which used this diagnostic kit for SARS diagnosing. Comparing with other detection kits now used, the antigen-capturing ELISA has stronger specificity and higher sensitivity, and more fits for rapid confirming and diagnosing of SARS cases, SARS epidemiological investigation and SARS epidemic source research. It is necessary to establish a rapid and accurate diagnostic method for controlling the epidemic of severe acute respiratory syndrome (SARS). Cooperating with Henan Bioengineering Research Center, we developed a new diagnostic kit for antibodies to SARS virus based on antigen-capturing ELISA. Here we report the clinical detection results obtained from several hospitals which used this diagnostic kit for SARS diagnosing. Comparing with other detection kits now used, the antigen-capturing ELISA has stronger specificity and higher sensitivity, and more fits for rapid confirming and diagnosing of SARS cases, SARS epidemiological investigation and SARS epidemic source research.
作者 刘萱 李平 石玉玲 易艳萍 任冽 匡铁吉 段昭辉 王云龙 马清钧 曹诚
机构地区 军事医学科学院生物工程研究所 广州军区广州总医院 中国人民解放军第 中山大学附属第二医院 河南省生物工程技术研究中心
出处 《病毒学报》 CAS CSCD 北大核心 2004年第2期172-174,共3页 Chinese Journal of Virology
关键词 严重急性呼吸综合征 SARS 病毒 双抗原夹心法 诊断试剂盒 血清标本 severe acute respiratory syndrome(SARS) antigen-capturing ELISA
分类号 R373.9 [医药卫生—病原生物学] R446.61 [医药卫生—诊断学]
  • 相关文献

参考文献5

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二级参考文献8

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共引文献10

同被引文献9

  • 1Marra MA, Jones SJ, Astell CR,et al. The genome sequence of the SARS-associated coronavirus.Science,2003,300:1399-1404.
  • 2Rota PA,Oberste MS,Monroe SS,et al.Characterization of a novel coronavirus assocaited with severe acute respiratory syndrome. Science,2003, 300: 1394-1399.
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  • 5Poutanen SM,Low DE,Henry B,et al. Identification of severe acute respiratory syndrome in Canada. N Engl J Med,2003,348:1995-2005.
  • 6Tan YJ, Goh PY, Fielding BC, et al.Profile of antibody responses against severe acute respiratory syndrome coronavirus recombinant proteins and their potential use as diagnostic markers.Clin Diagn Lab Immunol,2004,11:362-371.
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  • 9洪涛,王健伟,孙异临,段淑敏,陈良标,屈建国,倪安平,梁国栋,任丽丽,杨仁全,郭岚,周为民,陈杰,李德新,许文波,徐红,郭元吉,戴淑玲,毕胜利,董小平,阮力.电镜观察从非典型肺炎患者尸检标本中发现衣原体样和冠状病毒样颗粒[J].中华医学杂志,2003,83(8):632-636. 被引量：65

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二级引证文献3

病毒学报
2004年 第2期

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