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中风后遗症气虚血瘀大鼠病证模型运动神经传导的研究

The study of motor nerve conduction of the stroke sequela models of rats which are lack of Qi and with blood silted
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摘要 中风后遗症是指中风经过治疗 ,神志清醒后遗留的半身不遂、言语不利、口眼歪斜等症状。中医药防治中风后遗症有其特长和优势。目的 :研究中风后遗症“气虚血瘀”大鼠模型运动神经传导的变化。方法 :建立中风后遗症“气虚血瘀”大鼠模型 ,用肌电图仪记录大鼠坐骨神经传导速度和波幅变化。结果 :刺激组 (SG)毛发相对黯淡无光、卷曲 ,精神萎糜 ,表情惊恐 ,消瘦 ,肢体无力 ,摄食减少 ,饮水减少 ,手术伤口愈合迟缓。SG组符合中医气虚血瘀证候。在传导速度方面和波幅方面 ,NSG组和NG组存在显著差异性。结论 :可以认为非刺激组 (NSG)大鼠的运动神经传导速度和波幅早期出现了异常 ,伴随着脑梗塞进入恢复期的延长 ,其运动神经传导和波幅也有一定的恢复 ,不过恢复速度很慢 ;而刺激组 (SG)则变化较小 。 Objective:Study the change of the motor nerve conduction of the stroke sequela models of rats which are lack of Qi and with blood silted.Methods:Make the stroke sequela models of rats which are lack of Qi and with blood silted.Employ electromyography meter record nerve conduction velocity and amplitude of wave of sciatic nerve of the rats.Results:SG group rats hair relative intensive dark、convoluted,depressed、emotional panic、thinness、ingestion decrease,operatives car healing retardation,coincidence the sign of lack of Qi and with blood silted which belong to the traditional Chinese medicine;Accoring to the motor nerve conduction velocity,Theere is significance difference between SG group and NSG group.Conclusion:We can think there have disorder in motor nerve conduction velocity and wave amplitude in the earlier period of NSG group,when the time elongation after cerebral in farction rats get into convalescent,there ia some discovery in their motor nerve conduction velocity and wave amplitude,but it is slowly,after all,there is little changes in SG group,maybe it is the electric stimulation that facilitate rehabilitation of the motor nerve.
出处 《中医药学刊》 2004年第6期1008-1010,共3页 Study Journal of Traditional Chinese Medicine
基金 国家自然科学基金( 3 9870 93 8)
关键词 中风后遗症 气虚血瘀 动物模型 运动神经传导 中医药防治 stroke sequela lack of Qi and with blood silted model motor nerve conduction
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参考文献3

  • 1[2]Longa EZ, Weinstein PR, Carson S, et al. Reversible middle cerebral artery: occlusion without craniotomy in rats [J].Stroke, 1989, 20: 84
  • 2王键,胡建鹏.缺血性中风气虚血瘀证动物模型的初步研究[J].安徽中医学院学报,1999,18(2):46-49. 被引量:50
  • 3[6]Ochoa J, Fowlerd TJ, Gilliatt R W. Anatomical changes in peripheral nerves compressed by a pneumaric tourniquet [J]. J Anat, 1972, 113:433~455

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