摘要
本研究应用PCR技术对女性生殖道尖锐湿疣、可疑湿疣、假性湿疣、宫颈息肉、宫颈糜烂、慢性阴道炎等良性病变以及正常阴道组织进行HPV—DNA检测,结果HPV—DNA阳性检出率分别为 98.2％(56/57)、71.4％(15/21)、40.4％(19/47)、76.2％(16/21)、77.3％(17/22)、16％(4/25)和 10.7％(3/28),HPV6和 11型感染率分别占 85.7％(48/56)、80.0％(12/15)、26、3％(5/19)、50％(8/16)、17.6％(3/17)、25％(1/4)、0。提示,在对临床病变典型的病例进行HPV—DNA检测的同时,更应重视临床表现不典型甚至正常组织中 HPV—DNA的亚临床感染,这对生殖道恶性肿瘤的早期发现和预防有着重要意义。
This paper reported the results of HPV-DNA examination of condyloma acuminata (CA) and some other benign lesions in the female genital tract. The investigation showed that HPV-DNA positive rates were 98. 2% (56/57) in CA, 71. 4% (15/21) in suspected CA, 40. 4% (19/47) in pseudocondyloma, 76. 2% (16/21) in cervical polyp, 77. 3% (17/22) in chronic cervicitis, 16. 0% (4/25) in chronic vaginitis and 10. 7% (3/28) in normal vaginal tissues, respectively. Among these, the infective rate of HPV 6 and 11 was found to be 85. 7% (48/56), 80. 0% (12/15), 26. 3% (5/ 19) ,50.0% (8/16), 17. 6 (3/17), respectively in the former five diseases. HPV 6 and 11 were detected in only one case of chronic vaginitis, but not found in the normal tissues. This study indicated that at the present time while HPV infection is increasing, we should pay more attention to the atypical cases, even subclinical infection of normal tissues in the same time when typical cases are investigated. This is also very important to detect malignant diseases or to prevent them more earlier.
出处
《白求恩医科大学学报》
CSCD
1993年第5期457-459,共3页
Journal of Norman Bethune University of Medical Science
关键词
尖锐湿疣
诊断
乳头状瘤病毒
分析
Papillomavirusse/AN
acuminata/DI
condylomata cervicitis/DI
polymerase chain reaction /MT
