摘要
目的 :分析门诊的糖尿病患者的临床特点及分型情况 ,以期对门诊糖尿病的就诊、教育及随访等提供依据。方法 :对近 1年来 2 1 2 8例门诊糖尿病患者进行资料登记 ,统计其各项临床资料 ,进行临床特征的分析。根据谷氨酸脱羧酶 (GAD)抗体初步分型 ,并分析GAD抗体与年龄、性别、病程等的关系。结果 :新发糖尿病患者 91 8例(4 3.1 4 % ) ;4 0岁以上的患者 1 883例 (88.6 % )。门诊GAD抗体检测 782例 (36 .7% ) ,阳性率为 4 .2 %。临床 1型糖尿病 1 2例 ,阳性率 33.3% ;2型 76 4例 ,阳性率 3.8%。男女不同性别GAD抗体阳性率分别为 5 .1 %和 3.2 % (P >0 .0 5 )。 1 ,5 ,1 0及 1 0年以上不同病程糖尿病患者GAD抗体阳性率分别为 4 .4 % ,4 .8% ,1 .7%和 4 .9% (P >0 .0 5 )。结论 :新发糖尿病常见于 4 0岁以上中老年患者。糖尿病分型仍以 2型为主。GAD抗体阳性率与性别。
Objective To determine the clinical characteristics of diabetic outpatients and their classification,and to provide some suggestions for diagnostics, education and follow up of outpatients.Methods We analyzed the data of 2 128 outpatients recorded in the past year, and studied the clinical characteristics, distribution of types and relation between glutamate decarboxylase antibody(GADA)and age, sex and duration. Results Of all the patients,918(43.1%)were new onset, and 1 883(88.6%) aged 40 or older.Altogether 782(36.7%)of the patients were done with GADA examination and 4.2% of them were GADA positive.Twelve patients were type 1 diabetes and 764 were type 2 diabetes, respectively with 33.3% and 3.8% GADA positive.The prevalence of GADA positive was 5.1% for men and 3.2% for women( P >0.05). The frequencies of GADA positive in patients with different duration (1 year, 5 years, 10 years and more) were 4.4%, 4.8%, 1.7% and 4.9%( P >0.05)respectively.Conclusion The new onset population of the studied patients is dominated by 40 year olds or older. Type 2 diabetes is the main type in the diabetes spectrum. The frequency of GADA positive is irrelevant to sex and duration.
出处
《中南大学学报（医学版）》
CAS
CSCD
北大核心
2004年第2期184-186,共3页
Journal of Central South University ：Medical Science
基金
国家"十五"科技攻关项目 (2 0 0 1BA70 2B0 4 )
