摘要
目的 探讨广东省社区人群肠易激综合征 (IBS)的患病率及危险因素。方法 用整群、分层、随机抽样的方法在广东省内对广州市、惠州市及惠阳县马安镇 (代表农村 )三地的常住人口中 18～ 80岁的居民进行面访式问卷调查作为初查 ,了解按Manning标准加以补充 (含便秘症状 )及罗马Ⅱ(RomeⅡ )标准的IBS的患病率和危险因素。结果 (1)共调查 4 178人 ,其中男 190 7人 ,女 2 2 71人 ,平均年龄 (43± 14 )岁 ,应答率为 98% ;(2 )广东省有症状符合RomeⅡ标准的IBS的标化患病率为5 6 7% ,符合Manning标准的IBS的标化患病率为 11 5 0 % ,患病率无城乡和年龄差别 ,男女患病率之比分别为 1∶1 2 5 (按RomeⅡ标准 )和 1∶1 34(按Manning标准 ) ;(3)经单因素和多因素回归分析 ,服非甾体类抗炎药 (NSAID) (OR =3 83)、食物过敏史 (OR =2 6 8)、心理障碍性疾病 (OR =2 18)、生活事件(OR =1 89)、肠炎或痢疾史 (OR =1 6 3)及消极应对方式 (OR =1 2 8)等为最可能的危险因素。结论 IBS是广东省的常见病 ,应引起重视 ;食物过敏史等为最可能的危险因素 ,值得进一步研究。
Objective To explore the prevalence of irritable bowel syndrome (IBS) and its risk factors in Guangdong province. Methods A questionnaire was used to screen IBS by face-to-face interviews according to Manning (modified including symptoms of constipation) and Rome Ⅱ criteria .Random clustered sampling involving permanent inhabitants aged 18-80 years was carried out under stratification of urban and suburban areas. Potential risk factors were explored by comparing the frequencies among IBS group and non-IBS group using χ 2 and logistic analysis of multivariate adjusted for age and gender. Results A total of 4178 residents (male 1907,female 2271) were investigated . Mean age among the responders was (43±14) years. The response rate was 98%.The adjusted prevalence of IBS in Guangdong province is 5.67% according to the modified RomeⅡ criteria ,and is 11.50% according to Manning criteria. There is no difference between urban and suburban areas .The female was predominant in IBS, and the ratio of male to female was 1∶1.25(Rome Ⅱ) and 1∶1.34 (Manning). The age was poorly correlated with the prevalence. Events including history of analgesic use such as NSAID ( OR =3.83), history of food allergies ( OR =2.68), psychological distress ( OR =2.18), life events ( OR =1.89), history of dysentery ( OR =1.63) and negative coping style ( OR =1.28) are highly associated with IBS ( P <0.05). Conclusion IBS is a common disorder in Guangdong Province which deserves greater care and further investigation.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2004年第4期278-281,共4页
National Medical Journal of China
