摘要
本文报道用自力霉素和5-氟尿嘧啶从不同途径治疗Ⅱ期原发性肝癌84例的结果。其中非手术者30例和姑息性肝癌切除者16例均为静脉给药,余38例为肝动脉结扎和/或肝动脉灌注,门静脉灌注给药。治疗结果表明:完全缓解(CR)2例(2.4％),部份缓解(PR)13例(15.5％),有效率(CR+PR)为17.9％;AFP下降10例(11.9％);治疗后1年生存率为22.6％,治疗后生存8.04±6.45月(2～43月),插管组的治疗效果优于静脉给药者。提示MF方案对原发性肝癌治疗右一定效果。
From Jan. 1978 to Dec. 1989. 84 patients of Primary Liver Cancer (PLC) in Ⅱ stage were treated with MITOMYCIN(M) and 5-FLUOROURACIL(F) chemotherapy. Results of treatment CR rate was 2.4%, PR rate was 15.5%,total response rate (CR+PR) was 17.9%; AFP decrease rate was 11.9%; the one-year survival rate was22.6%; the mean survival were 8. 04±6. 45 months (2-43 months). Therapeutic effec-acy by hepatic artery ligation and/or infusion, and portal vein infusion was better than intravenous infusion treated for PLC with MF regimen. The result of this study suggested that MF chemotherapy may be effective in the treatment of Ⅱ stage PLC.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1993年第6期527-529,共3页
Chinese Journal of Cancer
关键词
癌
肝肿瘤
药物疗法
Primary Liver Cancer Chemotherapy
