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亚硝化煤尘提取物的致突变性与煤样中挥发分含量的关系初探 被引量:2

STUDIES ON RELATIONSHIP OF MUTAGENICITY OF NITROSATED COAL DUST EXTRACTS AND CONCENTRATION OF VOLATILE COMPONENT OF COAL DUST SAMPLES
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摘要 本文报道测定采自山西省五煤矿烟煤样品(5种)挥发分含量结果,并将其亚硝化提取物的致穷变性进行比较,结果显示:烟煤A、B、C、E和F挥发分含量(%)分别为16.27、13.14、16.65、26.87和24.56,其中以烟煤E挥发分含量最高。5种煤样亚硝化提取物致突变性检测结果表明:煤样E和F的亚硝化提取物经Ames试验和SOS显色试验,其结果均呈现致突变性,且E煤样致突变性强于F煤样。本研究结果提示:烟煤样品中挥发分含量与其亚硝化提取物的致突变性有一定相关关系。挥发分含量较高的煤样,其亚硝化提取物的致突变性相应也较强。 Concentration of volatile component of five bituminous coal dust samples from Shanxi province was determined and the relationship of concentration of volatile component and mutagenicity of nitrosated coal dust extract from same coal dust sample was studied in this paper. The results showed that concentration of volatile component of bitumionous A,B,C,E and F was 16.27,13.14,16.25,26.87 and 24.56% respectively. Sample E had the highest concentration of volatile component among five coal samples. Nitrosated coal dust extracts from sample E and F were mutagenic in Ames assay and SOS chromotest. The mutagenic potency of the two nitrosated extracts is higher in the bitumi- nous E than in that of the bituminous F. This studies indicated tha level of mutagcnic potency of the nitrosated extracts parallels the concentration of volatile components of the bituminous coal dust sample. The nitrosated extract from the coal dust sample with high concentration of volatile may has great mutagenicity.
出处 《癌变·畸变·突变》 CAS CSCD 1993年第2期39-40,29,共3页 Carcinogenesis,Teratogenesis & Mutagenesis
关键词 挥发分 亚硝化 致突变 煤尘 提取物 volatile component coal dust extracts nitrosation mutation
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