摘要
目的了解大黄加硫糖铝混悬液预防呼吸衰竭并发应激性溃疡出血的疗效。方法将55例需机械通气的呼吸衰竭患者随机分为两组,治疗组经鼻胃管给生大黄粉加硫糖铝混悬液,对照组予雷尼替丁入液静滴;观察两种方法对应激性溃疡出血、早发性呼吸机相关肺炎(VAP)、晚发性VAP和总VAP发病率的影响。结果两组应激性溃疡出血发生率、早发性VAP发病率和总VAP发病率近似,治疗组晚发性VAP发病率低于对照组。结论两组所用方法预防应激性溃疡出血疗效相似,但应用大黄加硫糖铝混悬液可降低呼吸衰竭机械通气患者晚发性VAP发病率。
To evaluate the prophylactic effect of rhubarb and sucralfate suspension for respiratory failure occurring with gastrointestinal bleeding induced by stress ulcer. Methods:55 patients were divided randomly into the treatment group and the controlled group. Patients in the treatment groups receiving rhubarb and sucralfate suspension through stomach tube,while those in the controlled group received ranitidine through intravenous drip. The influence of the two methods on gastrointestinal bleeding induced by stress ulcer,morbidity of early ventilator associated pneumonia (VAP),later VAP and total VAP were observed. Results:There was no significant difference in morbidity of gastrointestinal bleeding induced by stress ulcer,early VAP and total VAP between the two groups. The morbidity of later VAP of patients in the treatment group was significantly lower than that in the controlled group. Conclusion:The prophylactic effect of the two methods on gastrointestinal bleeding induced by stress ulcer is similar,but rhubarb and sucralfate suspension can dicrease the morbidity of later VAP in respiratory faliure patients who require mechanical vertilation.
出处
《中国中医急症》
2004年第6期358-359,共2页
Journal of Emergency in Traditional Chinese Medicine
