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手术方式对肛管直肠恶性黑色素瘤预后的影响 被引量:20

Effects of different surgical procedures on the prognosis of anorectal malignant melanoma
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摘要 目的比较经腹直肠肛门切除术(abdominoperinealresection,APR)与经肛局部扩大切除术(widelocalexcision,WLE)对肛管直肠恶性黑色素瘤(anorectalmalignantmelanoma,AMM)预后的影响。方法回顾分析1980年至2002年经手术治疗的42例AMM患者的临床资料。结果局部复发WLE术后62%、APR术后61%;平均生存时间WLE术后24.3个月,APR术后20.0个月;两组生存期比较,χ2=0.728,P>0.05,差异无显著性意义。结论AMM患者的预后与外科手术方式无关,应根据患者的综合因素来选择手术方式。 Objective To compare the effects of different surgical procedures on the prognosis of anorectal malignant melanoma(AMM). Methods The data of 42 cases with AMM from 1980 to 2002 in onr hospital were reviewed. Twenty nine patients underwent abdominoperineal resection(APR)including 23 radical resections, while 13 patients underwent wide local excision(WLE). Survival analysis was performed to compare the effects of these two different surgical procedures. Results The local recurrence rates in radical APR and WLE groups were 62%and 61%respectively. The mean survival time was 20.0 months in radical APR group and 24.3 months in WLE group(χ2=0.728,P >0.05). Conclusions Radical APR offers no survival advantage. The prognosis of AMM is not related to the surgical procedures, and surgical procedures should be selected on the basis of the comprenensive factors of the patients with AMM.
出处 《中华胃肠外科杂志》 CAS 2004年第3期211-213,共3页 Chinese Journal of Gastrointestinal Surgery
关键词 手术方式 肛管直肠恶性黑色素瘤 预后 外科治疗 复发 Malignant melanoma Anal canal Rectum Operation
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