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结膜松弛症的组织病理学观察 被引量:69

The analysis of histopathology of conjunctivochalasis
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摘要 目的 观察结膜松弛症组织病理学的改变。方法 对病变组 17例结膜松弛症患者松弛结膜组织和对照组 15例单纯白内障患者球结膜组织 ,采用苏木精 伊红染色、Verhoeff弹力纤维染色、Masson三色染色和Mallory磷钨苏木素染色方法。对照观察两组组织病理改变。结果 结膜松弛症患者结膜组织表现为结膜鳞状上皮增生 ,角化不全 ,基底细胞疏密不等的色素沉着 ,固有层间质出血 ,弹力纤维减少。结论 结膜松弛症患者的松弛结膜组织发生了结膜上皮增生 ,弹力纤维减少及慢性炎性病变等病理改变。弹力纤维的减少可能是本病的主要发病原因之一。 (中华眼科杂志 ,2 0 0 4,40 :3 7 3 9) Objective To observe the his topathological change of conjunctivochalasis Methods Conjunctival tissue was collected from 17 patients with conjunctivochalasis and 15 simple cataract patients. By HE/Verhoeff elastic fiber staining, the histopathological changes of conjunctival tissues in the patients were compared with those of simple cataract patients. Results The pathologic changes in conjunctivochalasis patients were characterized with hyperplasia of squamous epithelium with parakeratosis, pigmentation with different level in basal cell, hemorrhage, edema of stroma, infiltration of lymphocyte and plasmocyte. The elastic fiber layer was decreased. Conclusion There was hyperplasia of conjunctival epithelium, decrease of elastic fiber and chronic inflammation in patients with conjunctivochalasis. The decrease of elastic fiber should be considered as major cause of the changes of conjunctiva. (Chin J Ophthalmol, 2004,40: 37-39)
出处 《中华眼科杂志》 CAS CSCD 北大核心 2004年第1期37-39,共3页 Chinese Journal of Ophthalmology
关键词 结膜松弛症 组织病理学 发病机制 手术方法 Conjunctival diseases Epithelium Hyperpl asia
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  • 1张兴儒 梁丽琼 等.结膜松弛致溢泪临床疗效观察[J].中华眼科杂志,1999,35(1):57-57.
  • 2童绎.核素泪道检查进展(综述)[J].国外医学:眼科学分册,1982,6(4):228-231.
  • 3Don Liu, M. D: Conjunctivochalasis: A cause of tearing and its management. Ophthalmic plastic and Reconstructive Surge 1986 2 (1): 25~28
  • 4张兴儒.结膜松弛与泪溢关系的临床研究[J].眼科,2001,10(4):224-226. 被引量:28
  • 5张兴儒,李青松,许琰,刘晔翔.眼结膜松弛的临床分级探讨[J].眼科,2001,10(6):361-361. 被引量:72

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