摘要
对43例标本采用嗜银染色,油镜下观察,进行了银染核仁组成区(AgNOBS)计数,并运用多功能图象分析仪测定其核仁面积及细胞核 DNA 含量。结果表明:正常口腔粘膜 AgNORs 颗粒计数低,分布集中,核仁面积小,多为圆形,鳞癌组 AgNORs 计数明显高于正常组,核仁面积显著增大,形状多为不规则形,白斑组介于二者之间,统计学分析各组间有显著差异。白斑及鳞癌组 DNA 含量较正常组增高,鳞癌组尤其明显,而且 AgNORs 计数高的病例,DNA 含量也较高,并倾向于形成非整倍体。
The argyrophil(AgNORs)technique was applied.Nucleolar area and DNA content weredetermined by Leitz texture analysis system(TAS).The AgNORs counts,nucleolar areaand DNA content increase in grades from nomal epithelium through leukoplakias to car-cinomas.The AgNORs counts in aneuploid cases are higher than that in diploid cases.These correlations are statistically significant.
出处
《华西口腔医学杂志》
CAS
CSCD
北大核心
1992年第1期26-28,T003,共4页
West China Journal of Stomatology
