摘要
目的 分析应用静脉滤器结合溶栓和抗凝治疗在深静脉血栓患者治疗及预防肺动脉栓塞的长期随访结果。方法 2 4例急性或亚急性深静脉血栓患者 ,其中男 13例 ,女 11例 ;年龄 14～ 86岁 ,平均 5 2 4岁。 2 4例患者经皮经股静脉植入静脉滤器。 2例在术中辅以深静脉导管尿激酶溶栓治疗 ,2 0例在术后进行尿激酶静脉溶栓治疗。同时皮下注射低分子肝素 10d ,口服华法林 6个月。结果 全部病例介入操作成功。对全部病例临床平均随访 15个月 ( 10～ 4 8个月 )。术后一周内 18例患者的下肢水肿及疼痛迅速消失 ,其余 6例患侧肢体肿胀、无力症状均有不同程度减轻。本组没有发生滤器移位及腔静脉血栓阻塞和肺栓塞病例 ,也没有发生出血性并发症。结论 静脉滤器植入结合溶栓和抗凝是治疗急性或亚急性下肢深静脉血栓形成的一种安全、有效的方法 。
Objective To analyze retrospectively long term follow up of inferior vena cava filters in conjunction with thrombolysis and anti coagulant therapy in prevention and treatment of pulmonary embolism (PE) in 24 patients with deep vein thrombosis (DVT) Methods This study included 13 males and 11 females with an average age of 52 4 years (14-86 years) Percutaneous implantation of inferior vena cava filters was performed via a femoral vein in 24 patients with acute or subacute DVT, of whom two were given conjunctive catheter based urokinase thrombolysis After the procedure, 20 patients underwent intravenous urokinase thrombolysis with subcutaneous low weight molecular heparin for 10 days and subsequent oral warfarin for six months Results All patients underwent a successful interventional procedure with an average 15 month (10-48 months) follow up One week after the procedure, relief of symptoms related to DVT was achieved in all the 24 patients Neither filter migration and thrombolic occlusion of filter nor PE and major hemorrhage were observed in this series Conclusion The use of inferior vena cava filters in conjunction with thrombolysis and anti coagulant therapy is a safe and effective treatment modality in patients with DVT, which can be used to prevent subsequent PE
出处
《中国介入心脏病学杂志》
2004年第2期71-73,共3页
Chinese Journal of Interventional Cardiology
