摘要
目的观察32℃亚低温对实验性脑出血大鼠24h内病死率和脑组织钙含量的影响。方法将134只大鼠分成两组:①68只大鼠用于病死率观察;②66只大鼠用于脑组织钙含量测定。两组再分成假手术对照组、常温脑出血组及亚低温脑出血组。结果常温组24h内病死率为36.7%,亚低温组为4.6%;脑组织钙含量常温组较对照组和亚低温组为高。结论亚低温治疗能减少脑出血后脑组织钙的增加,减少钙平衡失调,显著减少实验性脑出血大鼠24h内病死率。
Objective To study the effects of moderate hypothermia on the mortality during twenty-four hours and the content of calcium in the brain after experimental cerebral hemorrhage in rats. Methods Of 134 rats were divided into two groups: ①68 rats were used for observing the mortality; ②66 rats were used for determining the content of calcium in the brain. Every group was divided into three subgroups:sham-operated group, nor-morthermic group, hypothermic group. Results During 24 hours after cerebral hemorrhage, the mortality is 36.67% in the normothermic group, and it is 4.55% in the hypothermic group. In the normothermic group, the content of calcium is remarkablely highter than that of the sham-operated group and the hypothermic group. Conclusion Hypothermic therapy can reduce the mortality and the content of calcium in the brain after experimental cerebral hemorrhage in rats.
出处
《中国微侵袭神经外科杂志》
CAS
2004年第5期225-226,共2页
Chinese Journal of Minimally Invasive Neurosurgery
