摘要
目的 :探讨太空微重力对鸡胚前庭神经元形态发育的影响。方法 :随机选取太空发育鸡胚和地面发育鸡胚各 2只 ,利用计算机显微测量技术测量前庭神经元切面的面积、周长、形态系数 ,每只鸡胚测量 2 0 0个神经元。结果 :2只太空发育鸡胚的前庭神经元切面面积的中位数分别是 2 30 .5 5 1 μm2 和 2 0 2 .81 9μm2 ,均高于 2只地面发育鸡胚的 1 6 2 .6 5 9μm2 和 1 2 3.1 38μm2 ;周长的中位数分别是 5 8.836 μm和 5 5 .36 5 μm ,高于地面鸡胚的 4 9.35 7μm和4 3.4 81 μm ;形态系数的中位数分别是 0 .86 2和 0 .86 4 ,与地面鸡胚的 0 .85 4和 0 .86 1比较 ,差异无统计学意义 (P >0 .1 )。结论 :太空发育鸡胚的前庭神经元体积大于地面发育鸡胚前庭神经元体积 ,而形状无差异 。
Aim: To study whether the space microgravity affect the morphological development of vestibular neurons of chicken embryos. Methods: Two embryos hatched in the space shuttle and two embryos hatched on the ground were chosen for this study randomly. The area, perimeter, and morphological coefficient of the neuron section were measured by using the computer micro measuring technique. A total of 200 neurons were examined for every chicken embryo. Results: For the two embryos hatched in the space, the median of the section area, perimeter, and the morphological coefficient for the vestibular neurons were 230.551 μm 2 and 202.819 μm 2, 58.836 μm and 55.365 μm, and 0.862 and 0.864, respectively,and those for the two embryos hatched on the ground were 162.659 μm 2 and 123.138 μm 2, 49.357 μm and 43.481 μm, and 0.854 and 0.861, respectively.There was significant difference in section area and perimeter( P <0.000 1),but no difference in morphological coefficient ( P >0.1) between the two groups. Conclusion: The volume of vestibular neurons of chicken embryo hatched in the space is bigger than that on the ground but the shapes of them has no discrepancy. Microgravity might affect the morphological development of vestibular neurons of chicken embryo.
出处
《郑州大学学报（医学版）》
CAS
北大核心
2004年第3期452-455,共4页
Journal of Zhengzhou University(Medical Sciences)
关键词
航天飞机
鸡胚
前庭神经节
微重力
发育
space shuttle
chicken embryo
vestibular ganglion
microgravity
development
