摘要
目的 建立双氯芬酸钠肠溶片释放度测定方法。方法 采用UV法测定双氯芬酸钠肠溶片释放度 ,测定波长为 2 76nm。结果 双氯芬酸钠线性范围为 6 .0～ 2 0 .0 μg/ml,r =0 .9998;平均回收率为 99.8% ,RSD =0 .3% (n =9)。 结论 本法简便、准确 ,可作为双氯芬酸钠肠溶片释放度测定方法。
Objective To establish a method for determination of dissolution of diclofenac sodium enteric-coated tablets. Methods Determination of dissolution of diclofenac sodium enteric-coated tablets by UV method.Results The linear range was 6.0～20.0 μg/ml,r = 0.9998;the average recoveries was 99.8%, RSD=0.3% (n=9) .Conclusion The method is simple, accurate ,which may be a suitable method for determination of dissolution of diclofenac sodium enteric-coated tablets.
出处
《广东药学》
2004年第2期18-20,共3页
Guangdong Pharmaceutical Journal
关键词
双氯芬酸钠肠溶片
释放度
紫外分光光度法
diclofenac sodium enteric-coated tablets
dissolution
ultraviolet-spectrophotometric method.
