摘要
目的 :考核各种H pylori感染诊断方法 ,试图证明分离培养仍是细菌性感染诊断的最可靠方法。方法 :315例胃十二指肠疾病患者同时进行胃活检组织分离培养 ,病理切片找菌 ,快速脲酶试验 ,14 CO2呼气试验检查 ,比较它们之间的检出率差异。结果 :四种方法各自的总检出率差异无显著性。以分离培养为金标准 ,其他方法的误诊误治率可达 12 0 6 %～ 2 2 2 2 %。各种诊断方法对H pylori感染的实际检出率差异存在着显著性。结论 :本研究提示 ,分离培养应为H pylori感染临床诊断的金标准。
Objective:Various methods for the diagnosis of Helicobacter pylori infection were studied to confirm that culture was still the most trustworthy one.Methods:315 patients with gastric and duodenal diseases were examined to determine Helicobacter pylori infection by gastric mucosal biopsy culturing,pathological examination,rapid urease test and 14CO 2 breath test.Differences of positive rate between these methods are compared.Results:No Significant difference exists between four methods.If culture was employed as the gold standard,rate of misdiagnosis and wrong therapy are 12.06%～22.22%.Conclusion:This research suggests that culture should be the gold standard for diagnosis of H.pylori infection.
出处
《中国微生态学杂志》
CAS
CSCD
2004年第2期80-82,共3页
Chinese Journal of Microecology
