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急性高容量血液稀释对腰麻下剖宫产术中低血压的防治 被引量:22

Acute hypervolume hemodilution for prevention of spinal hypotension during cesarean section
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摘要 目的 :观察 70 6代血浆联合复方氯化钠行高容血液稀释 (AHH)对剖宫产术腰麻后低血压的防治效果 .方法 :ASA Ⅰ~Ⅱ级拟行剖宫产术的健康初产妇 5 2例 ,随机分入Ⅰ组 (n =2 0 ) ,Ⅱ组 (n =32 ) .两组患者分别于腰麻前 2 0min内静脉输注复方氯化钠 2 0 0mL ,复方氯化钠及 70 6代血浆各 5 0 0mL .均采用 1 0mg 5g/L布比卡因重比重液实施腰麻 ,腰麻后低血压持续超过 2min者 ,静注麻黄素 1 0mg .比较两组腰麻后低血压、恶心、呕吐等的发生率及麻黄素应用率 .同时比较两组新生儿Apgar评分 .结果 :Ⅱ组腰麻后低血压发生率较低 (P <0 .0 1 ) ,恶心、呕吐并发症少 (P <0 .0 1 ) ,麻黄素使用率低 (P <0 .0 1 ) ,同Ⅰ组相比有显著的统计学差异 .两组新生儿Apgar评分相仿 ,均较好 .结论 :以复方氯化钠联合 70 AIM: To determine whether acute hypervolume hemodilution (AHH) with low molecule 6% hetastarch and Ringer’s solution lowers the incidence of spinal hypotension during cesarean section (CS). METHODS: 52 ASAⅠ-Ⅱ healthy parturients to have CS were randomly divided into two groups. Within 20 min pre spinal anesthesia, those in groupⅠ( n =20) received 200 mL of Ringer’s solution combined 500 mL of 6% low molecule hetasearch, and those in groupⅡ ( n =32) 500 mL of Ringer’s solution. Spinal anesthesia was performed with 10 mg of 5 g/L bupivacaine hyperbaric soloution in all parturients. Hypotension lasting ≥2 min was treated with IV bolous of ephedrine 10 mg and the neonatal Apgars scores were recorded. The incidences of spinal hypotension, nausea and vomiting and the use of ephedrine were compared between the two groups. RESULTS: The incidences of spinal hypotension, nausea and vomiting and event such as the administration of ephedrine in groupⅡwere significantly lower than those in groupⅠ ( P >0.01). The neonatal Apgar scores were high and similar in both groups ( P >0.05). CONCLUSION: The AHH with 6% low molecule hetastarch and Ringer’s solution can effectively prevent spinal hypotension during CS.
出处 《第四军医大学学报》 北大核心 2004年第7期663-665,共3页 Journal of the Fourth Military Medical University
基金 第四军医大学"金桥工程"(0 1 0 1 5)
关键词 706代血浆 复方氯化钠 血液稀释 麻醉 脊髓 低血压 剖宫产术 hetastarch, low molecule Ringer’s solution hemodilution anesthesia, spinal hypotension cesarean section
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