摘要
随机比较释放左旋18甲基炔诺酮的宫内节育器(LNG-IUD)和皮下埋植 Norplant-2各100例,观察使用36个月共3 100妇女月的避孕效果和可接受性。仅1例使用 LNG-IUD 者妊娠。不规则出血为终止的最常见原因,在使用的第24和36个月,因出血终止率 Norplant-2组分别为每百妇女年17.3％和26.8％,在 LNG-IUD 组均为3.3％,差异极为显著。因闭经和疼痛取器仅发生在 LNG-IUD 组。其闭经的百分率在使用的第二年底最高可达29.3％。使用的36个月中 Norplant-2组有20％～40％经期延长。97％以上的受试者对所使用的方法感到满意。
A randomized comparative study of levonorgest-rel-releasing intrauterine device(LNG-IUD) andNorplant^R-2 implants was carried out in 200 womenfor 36 months.3 100 woman-months of use were ob-served with each device.Only one pregnancy occurredin users of LNG-IUD at the 12th month of use.Thechange in bleeding pattern was the most frequent rea-son of discontinuation.The discontinuationrate for irregular bleeding with Norplant^R - 2 was17.3% and 26.8% at 24 and 36 months,respective-ly,as compared to 3.3% with LNG-IUD both 24 and36 months.The differences were statistically signifi-cant.The removal for amenorrhea and pain only oc-curred in scceptors of LNG-IUD.The percentage ofamenorrhea in LNG-IUD was the highest(29.3%) atthe end of two years use.About 20%～40% of wo-rsen using Norplant^R-2had prolonged bleeding through36 months.More than 97% of subjects reported sat-isfaction to the methods used by themselves.
出处
《生殖医学杂志》
CAS
1992年第2期74-77,共4页
Journal of Reproductive Medicine
关键词
炔诺酮
宫内节育器
植入物
避孕
Norethindrone
Intrauterine devices
Implants
artificial
Contraception
