期刊文献+

端粒酶在宫颈癌诊断、治疗中的应用进展 被引量:1

暂未订购
导出
摘要 端粒酶在宫颈重度不典型增生和宫颈癌中的活性表达与在正常宫颈组织中的表达 ,差异显著 ,提示端粒酶在宫颈癌领域有诊断、治疗意义。作为宫颈癌筛查、早期诊断、判断预后的生物指标 ;端粒酶抑制剂可能作为宫颈癌治疗的一种辅助治疗。
出处 《南华大学学报(医学版)》 2004年第2期236-238,共3页 Journal of Nanhua University(Medical Edition)
基金 湖南省教育厅课题 ( 99C2 0 0 )
  • 相关文献

参考文献15

  • 1Couter CM, Avilion AA, LeFeuvre CE,et al. Telomerase shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity[J].The EMBO Journal, 1992,11:1921-1929.
  • 2Dahse R,Fielder W,Ernst G. Telomeres and telomrase : biological and clinical importance[J]. Clin Chemistry,1997,43(5):708-714.
  • 3Kim Nm,Piatyzek MA,Prowse K,et al. Specific association of human telomeres activity with immortal cells and cancer[J]. Science,1994,266:2011-2015.
  • 4Oishi T,Kigawa J,Minagawa Y,et al. Alteration of telomerase activity associated with development and extent of epithelial ovarian cancer[J]. Obstet Gyneocl,1998,91:568-571.
  • 5Nagai N, Oshita T,Murakani J,et al. Semiquantitive analysis of telomerase activity in cervical cancer and precancerous lesions[J]. Oncol Rep,1999,6(2):325-328.
  • 6Jarboe EA, Liaw KL,Thompson LC,et al. Analysis of telomerase as a diagnostic biomarker of cervical dysplasia and carcinoma[J]. Onxogene , 2002,21(4):664-673.
  • 7Takakura M,Kyo S,Kanaya T, et al. Expression of human telomerase subunits and correlation with telomerase activity in cercical cancer[J]. Cancer Res,1998,58(7):1558-1561.
  • 8Nakanko K, Watney E, McDougall JK. Telomerase activity and exression of telomerase RNA component and telomeres catalytic subunit gene in cervical cancer[J]. Am J Pathol, 1998,153(3):857-864.
  • 9ChangChien CC, Lin H, Leung SW, et al. Effect of acetic acid on telomerase activity in cervical intraepithelial neoplasia[J]. Gyneol Oncol, 1998,71(1):99-103.
  • 10Yatabe N, Kyo S, Kndo S,et al. 2-5A antisense therapy directed against human telomerase RNA inhibits telomerase activity and induce apoptosis without telomere impairment in cervical cancer cells[J]. Cancer Gene Ther,2002,9(7):624-630.

同被引文献3

引证文献1

二级引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部