期刊文献+

乳腺癌转移、侵袭相关基因研究

原文传递
导出
摘要 乳腺癌是女性常见的恶性肿瘤。每年约有30 %的乳腺癌患者发生癌细胞转移现象,导致发病率及死亡率上升,成为影响其疗效的主要原因。了解乳腺癌转移、侵袭相关基因对于预防和治疗乳腺癌转移具有重要作用。对近年来发现的乳腺癌转移、侵袭相关基因作一综述。
出处 《肿瘤研究与临床》 CAS 2004年第2期138-140,共3页 Cancer Research and Clinic
  • 相关文献

参考文献27

  • 1Ullrich A, Gray A, Tam A. Insulln-like growth factor I receptor primary structure:comparison with insulin receptor suggests structural determinants that define functional specificity[J]. EMBO J, 1986, 5:2503-2512.
  • 2Arboleda M, Lyons, Kabbinavar. Overexpression of AKT2/protein kinase Bb leads to up-regulation of bl integrins, increased invasion, and metastasis of human breast and ovarian cancer cells [J]. Cancer Res,2003, 63: 196-206.
  • 3Sliva D, Rizzo M T, English Denis. Phosphatidylinositol 3- kinase and NF- к B regulate motility of invasive MDA - MB231 human breast cancer cells by the secretion of urokinase-type plasminogen activator[J]. JBiol Chem, 2002, 277:31150-3157.
  • 4Wells A, Kassis J, Solava J. Growth factorinduced cell motility in tumor invasion [J].Acta Oncol, 2002, 41: 124-130.
  • 5Hazan R B, Phillips G R, Qian R. Exogenous expression of N -eadherin in breast cancer cells induces cell migration, invasion, and metastasis[J]. J Cell Biol, 2000,148: 779-790.
  • 6Christofori G, Semb H. The role of the celladhesion molecule E - cadherin as a tumour-suppressor gene[J]. Trends Biochem Sci, 1999, 24: 73-76.
  • 7Zlotnik A, Yoshie O. Chemolines: a new classification system and their role in immunity[J]. Immunity, 2000, 12:121-127.
  • 8Fernandis A Z, Prasad A, Band H. Regulation of CXCR4 - mediated chmotaxis and chemoinvasion of breast eancer cells [J].Oncogene, 2004, 23: 157-167.
  • 9Muller A, Homey B, Soto H. Involvement of chemokine receptors in breast cancer metastasis[J]. Nature, 2001, 410: 50-56.
  • 10Chen Y, Stamatoyannopoulos G, Song Ch.Down - regulation of CXCR4 by inducible small inteffering RNA inhibits breast cancer cell invasion in vitro [J]. Cancer Res,2003, 63:4801-4804.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部