摘要
目的 了解我院口腔科病房感染的病原体及细菌的耐药情况 ,为临床治疗提供依据。方法 对我院 1995～ 2 0 0 2年口腔科所有分离的细菌、真菌及药敏进行回顾性分析。结果 感染的病原体以革兰阳性球菌为主6 0 .6 % ,革兰阴性杆菌 31.3%、真菌 8.0 % ;在细菌感染中革兰阳性球菌占 6 5 .9% ,革兰阴性杆菌 34.1% ;革兰阳性球菌以金黄色葡萄球菌为主 5 2 .9% ,耐甲氧西林金黄色葡萄球菌 (MRSA) 6 5 % ,凝固酶阴性葡萄球菌中耐甲氧西林凝固酶阴性葡萄球菌 (MRCNS)占 78% ;革兰阴性杆菌以铜绿假单胞菌为主 ,占 33.6 % ,真菌以白色念珠菌为主 6 5 .6 % ;细菌的耐药性除万古霉素无变化外 ,其他抗生素的耐药性均有不同程度的升高 (P<0 .0 1)。结论口腔科病房感染的病原体虽以革兰阳性球菌为主 ,但革兰阴性杆菌和真菌已逐渐成为重要致病菌 ,抗生素的耐药率逐渐升高 ,应及时作细菌学检测 ,合理使用抗生素。
OBJECTIVE To search for the prevalence of nosocomial infection and the drug resistance in a comprehensive oral department. METHODS The bacterial and fungal isolates from oral department and their drug resistance were retrospectively analyzed during 1995-2003. RESULTS The most prevalent isolates of pathogens of nosocomial infection were still Gram-positive bacteria (60.6%),then Gram-negative ones (31.3%) and fungi (8.0%). Among bacteria,Gram-positive and Gram-negative bacteria were 65.9% and 34.11% ,respectively. In Gram-negative bacteria Pseudomonas aeruginosa was the major one (33.6%) and in Gram-positive bacteria Staphylococcus aureus (69.2%) was the most prominent and among the isolated strains MRSA and MRCNS were 65% and 78%,respectively. Candida albicans (65.6%) was the main type among all the isolated fungi,the percentage of resistant strains to antimicrobials was increased,except to vancomycin and imipenem. CONCLUSIONS Understanding the epidemiologic data and the changes in bacterial resistance profile is the prerequisite to use antibiotics properly,but it is difficult.
出处
《中华医院感染学杂志》
CAS
CSCD
2004年第5期595-597,共3页
Chinese Journal of Nosocomiology
关键词
病原体
抗生素
口腔科
药物敏感试验
Pathogens
Oral Department
Antibiotic
Susceptible testing
